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The map label for this gene is glmM

Identifier: 158336572

GI number: 158336572

Start: 3464424

End: 3465791

Strand: Reverse

Name: glmM

Synonym: AM1_3435

Alternate gene names: 158336572

Gene position: 3465791-3464424 (Counterclockwise)

Preceding gene: 158336577

Following gene: 158336569

Centisome position: 53.29

GC content: 50.8

Gene sequence:

>1368_bases
GTGGCAGCCGCAAAAGATGTGAACTTATTCGGAACGGATGGAATTCGAGGCCATGTCGGTCAACATCTCACCCCTCAATT
AGCGCTCCAAGTGGGCTTTTGTGCAGGACTTGAGTTGGGACAAGATGCATCTCCTCATCAGCCCTTTATCTTAGGCCAAG
ACTCTCGCAACTCTAGTGATATGTTAGCGATGGCGCTATCGGCAGGTCTGACCGCCGCTGGGCTAGATGTTTGGCATATC
GGATTATGTCCAACCCCCACCGTTGCCTACTTAACCCATCACACCGAAGCAGTAGGTGGCGTGATGGTCTCTGCCAGTCA
TAACCCGCCGGCAGATAATGGCATTAAATTTTTTCAAGCCAACGGTACTAAGCTCCCTCCCACCACTCAAGGGAAAATTG
AACAACGGATTCGAGCCTATAGCCAACAACAGCCCTCAGGCACTTGGGGACATCATTTCCATCGGCCTGAACTGACAAAA
TCTTATACTGATGCAATTCAAACCCCTTTACACGCTCAAGTCGATTTCCAAGGGTTGAAAGTCGTTCTGGATCTCGCTTG
GGGCGCAGCCACTCAGTTAGCGCCTGCTGTCTTTAAAGCCATGGGGGCTGAGGTCATTTGTTTACACGATCAGCCGGATG
GTGATCGTATTAACGTCAATTGCGGCTCTACACATTTAGCCCCCTTGAAAGCAGCCGTTAACTTACATGAGGCTGATGTC
GGCTTTGCCTTTGATGGCGACGCCGATCGCGTGCTCGCGATTGACTGTCAAGGCCGCACCGTGGATGGCGACTATATTCT
CTATCTGTGGGGCAAAGCTTTACAGCAGCAAAATCAGTTGCCCAAAGACCTGATTGTAGCCACGGTCATGTCCAATTTAG
GATTCGAATTGGCTTGGCAGCAGCAAGGCGGCACCCTCTTACGAGCAGCAGTGGGTGATCAAAATGTTCATGCTGAGATG
CTCAATCACGGCTCCATGCTAGGGGGCGAGCAATCTGGCCATATCCTATGTCCACACTATGGTGTCAGTGGCGATGGGTT
GTTAACGGCATTGCATTTGGCAACCATTATTTGTCAAAACAAGACCCGCCTTTCCTGTTTAGTGGATGACAGCTTTCAGA
CTTATCCCCAACTTCTCAAGAATGTGCGCGTCGAAGATCGCGATCGCAGACGCAATTGGCAAGAGTGCCAACCCCTCCAA
ACCCTGATTGATCAAGCTACGGACGATATGGGGGATCAAGGTCGAATTCTAGTGCGGGCTTCCGGCACAGAACCTCTCAT
TCGCGTCATGGTAGAAGCCCGCGATATGAGAATGGTCAACCATTGGACAGACCAATTAGTCCGTGCGGTTGAAACCCATC
TAGCCTAA

Upstream 100 bases:

>100_bases
TGGAGTGTATTGTCCAATGTCTGTTACTTCTCAATCTAAGCAGAAAAGTGTTACCAAAAGCGATCGCACCGTTCAACCTG
CCAAACTAGCGCGCAAAGTC

Downstream 100 bases:

>100_bases
AGCATCACTAGCTCGCCATTCACTTCTAGGCGTTTATAGTTGCTCAGGCATAAATAGCGATCGGCTAGGGTATCGGCATG
GCTGGGTTCTAGCCAGCCTA

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MAAAKDVNLFGTDGIRGHVGQHLTPQLALQVGFCAGLELGQDASPHQPFILGQDSRNSSDMLAMALSAGLTAAGLDVWHI
GLCPTPTVAYLTHHTEAVGGVMVSASHNPPADNGIKFFQANGTKLPPTTQGKIEQRIRAYSQQQPSGTWGHHFHRPELTK
SYTDAIQTPLHAQVDFQGLKVVLDLAWGAATQLAPAVFKAMGAEVICLHDQPDGDRINVNCGSTHLAPLKAAVNLHEADV
GFAFDGDADRVLAIDCQGRTVDGDYILYLWGKALQQQNQLPKDLIVATVMSNLGFELAWQQQGGTLLRAAVGDQNVHAEM
LNHGSMLGGEQSGHILCPHYGVSGDGLLTALHLATIICQNKTRLSCLVDDSFQTYPQLLKNVRVEDRDRRRNWQECQPLQ
TLIDQATDDMGDQGRILVRASGTEPLIRVMVEARDMRMVNHWTDQLVRAVETHLA

Sequences:

>Translated_455_residues
MAAAKDVNLFGTDGIRGHVGQHLTPQLALQVGFCAGLELGQDASPHQPFILGQDSRNSSDMLAMALSAGLTAAGLDVWHI
GLCPTPTVAYLTHHTEAVGGVMVSASHNPPADNGIKFFQANGTKLPPTTQGKIEQRIRAYSQQQPSGTWGHHFHRPELTK
SYTDAIQTPLHAQVDFQGLKVVLDLAWGAATQLAPAVFKAMGAEVICLHDQPDGDRINVNCGSTHLAPLKAAVNLHEADV
GFAFDGDADRVLAIDCQGRTVDGDYILYLWGKALQQQNQLPKDLIVATVMSNLGFELAWQQQGGTLLRAAVGDQNVHAEM
LNHGSMLGGEQSGHILCPHYGVSGDGLLTALHLATIICQNKTRLSCLVDDSFQTYPQLLKNVRVEDRDRRRNWQECQPLQ
TLIDQATDDMGDQGRILVRASGTEPLIRVMVEARDMRMVNHWTDQLVRAVETHLA
>Mature_454_residues
AAAKDVNLFGTDGIRGHVGQHLTPQLALQVGFCAGLELGQDASPHQPFILGQDSRNSSDMLAMALSAGLTAAGLDVWHIG
LCPTPTVAYLTHHTEAVGGVMVSASHNPPADNGIKFFQANGTKLPPTTQGKIEQRIRAYSQQQPSGTWGHHFHRPELTKS
YTDAIQTPLHAQVDFQGLKVVLDLAWGAATQLAPAVFKAMGAEVICLHDQPDGDRINVNCGSTHLAPLKAAVNLHEADVG
FAFDGDADRVLAIDCQGRTVDGDYILYLWGKALQQQNQLPKDLIVATVMSNLGFELAWQQQGGTLLRAAVGDQNVHAEML
NHGSMLGGEQSGHILCPHYGVSGDGLLTALHLATIICQNKTRLSCLVDDSFQTYPQLLKNVRVEDRDRRRNWQECQPLQT
LIDQATDDMGDQGRILVRASGTEPLIRVMVEARDMRMVNHWTDQLVRAVETHLA

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:
GO:0000287: Phosphoglucosamine mutase
GO:0005975: Phosphoglucosamine mutase
GO:0008966: Phosphoglucosamine mutase
GO:0016853: Phosphoglucosamine mutase
GO:0016868: Phosphoglucosamine mutase
GO:0046872: Phosphoglucosamine mutase

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=443, Percent_Identity=38.8261851015801, Blast_Score=273, Evalue=2e-74,
Organism=Escherichia coli, GI1788361, Length=454, Percent_Identity=28.6343612334802, Blast_Score=148, Evalue=9e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_ACAM1 (B0C132)

Other databases:

- EMBL:   CP000828
- RefSeq:   YP_001517746.1
- ProteinModelPortal:   B0C132
- SMR:   B0C132
- GeneID:   5682244
- GenomeReviews:   CP000828_GR
- KEGG:   amr:AM1_3435
- HOGENOM:   HBG644964
- OMA:   VHDRYIE
- ProtClustDB:   PRK14317
- BioCyc:   AMAR329726:AM1_3435-MONOMER
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 49462; Mature: 49330

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 106-106

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAAKDVNLFGTDGIRGHVGQHLTPQLALQVGFCAGLELGQDASPHQPFILGQDSRNSSD
CCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCHH
MLAMALSAGLTAAGLDVWHIGLCPTPTVAYLTHHTEAVGGVMVSASHNPPADNGIKFFQA
HHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEC
NGTKLPPTTQGKIEQRIRAYSQQQPSGTWGHHFHRPELTKSYTDAIQTPLHAQVDFQGLK
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEECHHHHE
VVLDLAWGAATQLAPAVFKAMGAEVICLHDQPDGDRINVNCGSTHLAPLKAAVNLHEADV
EEEEHHCCCHHHHHHHHHHHCCCEEEEEECCCCCCEEEEECCCCCCHHHHHHHEEEECCC
GFAFDGDADRVLAIDCQGRTVDGDYILYLWGKALQQQNQLPKDLIVATVMSNLGFELAWQ
CEEECCCCCCEEEEECCCCEECCCEEEEEEHHHHHHHHCCCHHHHHHHHHHHCCCEEEEE
QQGGTLLRAAVGDQNVHAEMLNHGSMLGGEQSGHILCPHYGVSGDGLLTALHLATIICQN
CCCCEEEEEECCCCCHHHHHHHCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHCC
KTRLSCLVDDSFQTYPQLLKNVRVEDRDRRRNWQECQPLQTLIDQATDDMGDQGRILVRA
CCEEEEEECCCHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEEE
SGTEPLIRVMVEARDMRMVNHWTDQLVRAVETHLA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AAAKDVNLFGTDGIRGHVGQHLTPQLALQVGFCAGLELGQDASPHQPFILGQDSRNSSD
CCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCHH
MLAMALSAGLTAAGLDVWHIGLCPTPTVAYLTHHTEAVGGVMVSASHNPPADNGIKFFQA
HHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEC
NGTKLPPTTQGKIEQRIRAYSQQQPSGTWGHHFHRPELTKSYTDAIQTPLHAQVDFQGLK
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEECHHHHE
VVLDLAWGAATQLAPAVFKAMGAEVICLHDQPDGDRINVNCGSTHLAPLKAAVNLHEADV
EEEEHHCCCHHHHHHHHHHHCCCEEEEEECCCCCCEEEEECCCCCCHHHHHHHEEEECCC
GFAFDGDADRVLAIDCQGRTVDGDYILYLWGKALQQQNQLPKDLIVATVMSNLGFELAWQ
CEEECCCCCCEEEEECCCCEECCCEEEEEEHHHHHHHHCCCHHHHHHHHHHHCCCEEEEE
QQGGTLLRAAVGDQNVHAEMLNHGSMLGGEQSGHILCPHYGVSGDGLLTALHLATIICQN
CCCCEEEEEECCCCCHHHHHHHCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHCC
KTRLSCLVDDSFQTYPQLLKNVRVEDRDRRRNWQECQPLQTLIDQATDDMGDQGRILVRA
CCEEEEEECCCHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEEE
SGTEPLIRVMVEARDMRMVNHWTDQLVRAVETHLA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA