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The map label for this gene is trxB [H]

Identifier: 158336393

GI number: 158336393

Start: 3288649

End: 3290313

Strand: Reverse

Name: trxB [H]

Synonym: AM1_3255

Alternate gene names: 158336393

Gene position: 3290313-3288649 (Counterclockwise)

Preceding gene: 158336394

Following gene: 158336392

Centisome position: 50.59

GC content: 55.02

Gene sequence:

>1665_bases
ATGGATAAGCCCGTCATTCTAACCATCGACGATGATCCAGCCGTGCTCCAAGCGATCGCCCGTGACCTGCGCAAGCAATA
TGGCGGTCGTTTCCGCATTATGCGGGCTGACTCTGGGACCAGTGCCCTGGATGCGACTCAGAAGCTCAAACTGCGCGGCG
ATACCGTGGCCCTCTTCCTGGCAGATCAGCGGATGCCCAATATGAGCGGAGTGGAATTTCTGGAACAGGCCAGCCCTATT
TTCCCCACTGCGAAGCGAGCGCTGCTGACGGCCTATGCCGATACCGATGCGGCGATATCTGCCATCAATGATGCCAACCT
GGACTACTATTTGCTCAAACCTTGGGATCCGCCAGAAGAGAAGTTGTATCCCGTTCTGGATGACTTAATCGCCGACTGGA
AAGCGAGCTTTAAACCAGAGTTTAAGGGAGTGAAAGTGATTAGCGATCGCTGGTCCCCGGACTCCCATGCCCTGCGCGAT
TTTCTCTCCCGCAACCAAATTCCCTACCGCTGGCTGGATATCGAAAGCGATCCTGAAGCCCAACAGTTGATCAGTCTGTC
CGGTGAAAAAGTGAGCCAGGCCGATCATCCTTGCCTTCCCCTCGTGATCCAAGCAGATGGCTCTAAACTGACGAGCCCCA
GCGTCACAGAACTGGCCCAAGCTCTGGGGCAAACGACCGAAGCGGCGAAGCCGTTCTACGATTTAGTGATTGTGGGGGGT
GGCCCAGCGGGGTTGGCTGCTGCTGTTTATGGTGCCTCTGAGGGACTGCGCACGGTGATGATTGAGCGCGAAGCGCCTGG
CGGCCAAGCAGGCACCAGCTCTCGCATTGAAAACTATTTGGGCTTTCCGGTTGGTTTAAGCGGCAGTGACCTGGCCCGCC
GCGCCGTTACCCAGGCCAAGCGCTTCGGTGTTGAAATTCTCACGCCCCAAGCTGGCCAAAGCCTGCGTACCGAGAACAAT
TACCATTTTTTGACGCTGTCTGATGGTAGCGAAATCAGCAGTCATGCCTTAATCCTGGCCCTGGGGGTCTCCTGGCGTAG
GCTAAACATGCCTGGCATTGAACAGTTTACGGGGGCAGGCGTGTACTACGGCGCAGCCCAAACGGAAGCCGCCGCCTGCA
CAAACGAAGAGGTCTACGTGGTAGGTGGTGCCAACTCAGCGGGCCAAGCAGCTATGTACTTTTCTAAGTTTGCCAAGACA
GTGCGCATATTGGTGCGGGGCGAGTCTCTCACTAAAAGCATGTCCCAATATCTGATTGACCAAATCGATGGCACAGACAA
CATTGAAGTGTTGCCGTTTCATAGTGTGGTGGAAGCTCAGGGGAGCGAGAAGCTGGAGCGGATTCTGGTCAAGGATTCCC
AGACCGATGAGATGAAAACGTTTGAGACCAATTCCCTGTTTATCTTTATCGGAGCAACCCCCAGTACGGATTGGTTAGGT
GACCAGGTATATCGCGATCAACGGGGCTTTATTTGTACGGGGCCAGATGTGGATACATCGTTAGGCTGGCCCCTGGAGCG
CGATCGCTTCTTGTTGGAAACCAACGTACCTGGCATTTTTGCGGTGGGTGATGTGCGCCATAACTCGATCAAACGGGTGG
CCTCTGGCGTGGGTGAAGGCTCTATTTGCGTCCAGTTTGTTCATCGCCATTTAGCCAACCTGTAG

Upstream 100 bases:

>100_bases
CCCTTCATTAGTTTCAGGTTGTACTGAGGTTTTGCACTATGCCTTTGACAAAGACTTTACAGTGGTACGAACTATCACCC
TTCAGTAGGAGTTAATCACA

Downstream 100 bases:

>100_bases
CGTATCCCCAATTTATAGGCAATTAATCCATGCTTTGTCCAGACGCTTTGACCCAGATAGAAGTCTTTCGCACACTGCCT
CCAGAACGCCTGGATTGGAT

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 554; Mature: 554

Protein sequence:

>554_residues
MDKPVILTIDDDPAVLQAIARDLRKQYGGRFRIMRADSGTSALDATQKLKLRGDTVALFLADQRMPNMSGVEFLEQASPI
FPTAKRALLTAYADTDAAISAINDANLDYYLLKPWDPPEEKLYPVLDDLIADWKASFKPEFKGVKVISDRWSPDSHALRD
FLSRNQIPYRWLDIESDPEAQQLISLSGEKVSQADHPCLPLVIQADGSKLTSPSVTELAQALGQTTEAAKPFYDLVIVGG
GPAGLAAAVYGASEGLRTVMIEREAPGGQAGTSSRIENYLGFPVGLSGSDLARRAVTQAKRFGVEILTPQAGQSLRTENN
YHFLTLSDGSEISSHALILALGVSWRRLNMPGIEQFTGAGVYYGAAQTEAAACTNEEVYVVGGANSAGQAAMYFSKFAKT
VRILVRGESLTKSMSQYLIDQIDGTDNIEVLPFHSVVEAQGSEKLERILVKDSQTDEMKTFETNSLFIFIGATPSTDWLG
DQVYRDQRGFICTGPDVDTSLGWPLERDRFLLETNVPGIFAVGDVRHNSIKRVASGVGEGSICVQFVHRHLANL

Sequences:

>Translated_554_residues
MDKPVILTIDDDPAVLQAIARDLRKQYGGRFRIMRADSGTSALDATQKLKLRGDTVALFLADQRMPNMSGVEFLEQASPI
FPTAKRALLTAYADTDAAISAINDANLDYYLLKPWDPPEEKLYPVLDDLIADWKASFKPEFKGVKVISDRWSPDSHALRD
FLSRNQIPYRWLDIESDPEAQQLISLSGEKVSQADHPCLPLVIQADGSKLTSPSVTELAQALGQTTEAAKPFYDLVIVGG
GPAGLAAAVYGASEGLRTVMIEREAPGGQAGTSSRIENYLGFPVGLSGSDLARRAVTQAKRFGVEILTPQAGQSLRTENN
YHFLTLSDGSEISSHALILALGVSWRRLNMPGIEQFTGAGVYYGAAQTEAAACTNEEVYVVGGANSAGQAAMYFSKFAKT
VRILVRGESLTKSMSQYLIDQIDGTDNIEVLPFHSVVEAQGSEKLERILVKDSQTDEMKTFETNSLFIFIGATPSTDWLG
DQVYRDQRGFICTGPDVDTSLGWPLERDRFLLETNVPGIFAVGDVRHNSIKRVASGVGEGSICVQFVHRHLANL
>Mature_554_residues
MDKPVILTIDDDPAVLQAIARDLRKQYGGRFRIMRADSGTSALDATQKLKLRGDTVALFLADQRMPNMSGVEFLEQASPI
FPTAKRALLTAYADTDAAISAINDANLDYYLLKPWDPPEEKLYPVLDDLIADWKASFKPEFKGVKVISDRWSPDSHALRD
FLSRNQIPYRWLDIESDPEAQQLISLSGEKVSQADHPCLPLVIQADGSKLTSPSVTELAQALGQTTEAAKPFYDLVIVGG
GPAGLAAAVYGASEGLRTVMIEREAPGGQAGTSSRIENYLGFPVGLSGSDLARRAVTQAKRFGVEILTPQAGQSLRTENN
YHFLTLSDGSEISSHALILALGVSWRRLNMPGIEQFTGAGVYYGAAQTEAAACTNEEVYVVGGANSAGQAAMYFSKFAKT
VRILVRGESLTKSMSQYLIDQIDGTDNIEVLPFHSVVEAQGSEKLERILVKDSQTDEMKTFETNSLFIFIGATPSTDWLG
DQVYRDQRGFICTGPDVDTSLGWPLERDRFLLETNVPGIFAVGDVRHNSIKRVASGVGEGSICVQFVHRHLANL

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=324, Percent_Identity=29.6296296296296, Blast_Score=122, Evalue=8e-29,
Organism=Escherichia coli, GI87081763, Length=313, Percent_Identity=29.073482428115, Blast_Score=110, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6321898, Length=329, Percent_Identity=31.9148936170213, Blast_Score=146, Evalue=8e-36,
Organism=Saccharomyces cerevisiae, GI6320560, Length=329, Percent_Identity=31.0030395136778, Blast_Score=144, Evalue=3e-35,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 60418; Mature: 60418

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKPVILTIDDDPAVLQAIARDLRKQYGGRFRIMRADSGTSALDATQKLKLRGDTVALFL
CCCCEEEEECCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHEEECCCEEEEEE
ADQRMPNMSGVEFLEQASPIFPTAKRALLTAYADTDAAISAINDANLDYYLLKPWDPPEE
ECCCCCCCHHHHHHHHCCCCCCCHHHHHEEEECCCCHHHHECCCCCCCEEEECCCCCCHH
KLYPVLDDLIADWKASFKPEFKGVKVISDRWSPDSHALRDFLSRNQIPYRWLDIESDPEA
HHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEEECCCCCCH
QQLISLSGEKVSQADHPCLPLVIQADGSKLTSPSVTELAQALGQTTEAAKPFYDLVIVGG
HHHHHCCCCHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCHHHCCCEEEEEEECC
GPAGLAAAVYGASEGLRTVMIEREAPGGQAGTSSRIENYLGFPVGLSGSDLARRAVTQAK
CCHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHH
RFGVEILTPQAGQSLRTENNYHFLTLSDGSEISSHALILALGVSWRRLNMPGIEQFTGAG
HCCEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCEEECCCCCHHHHCCCC
VYYGAAQTEAAACTNEEVYVVGGANSAGQAAMYFSKFAKTVRILVRGESLTKSMSQYLID
EEECCCCCHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHH
QIDGTDNIEVLPFHSVVEAQGSEKLERILVKDSQTDEMKTFETNSLFIFIGATPSTDWLG
HCCCCCCEEEEECHHHHHHCCHHHHHHHHHCCCCCCCCEEEECCEEEEEEECCCCCCCCC
DQVYRDQRGFICTGPDVDTSLGWPLERDRFLLETNVPGIFAVGDVRHNSIKRVASGVGEG
HHHHHCCCCEEEECCCCCCCCCCCCCCCCEEEEECCCCEEEECCCCHHHHHHHHHCCCCC
SICVQFVHRHLANL
HHHHHHHHHHHHCC
>Mature Secondary Structure
MDKPVILTIDDDPAVLQAIARDLRKQYGGRFRIMRADSGTSALDATQKLKLRGDTVALFL
CCCCEEEEECCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHEEECCCEEEEEE
ADQRMPNMSGVEFLEQASPIFPTAKRALLTAYADTDAAISAINDANLDYYLLKPWDPPEE
ECCCCCCCHHHHHHHHCCCCCCCHHHHHEEEECCCCHHHHECCCCCCCEEEECCCCCCHH
KLYPVLDDLIADWKASFKPEFKGVKVISDRWSPDSHALRDFLSRNQIPYRWLDIESDPEA
HHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEEECCCCCCH
QQLISLSGEKVSQADHPCLPLVIQADGSKLTSPSVTELAQALGQTTEAAKPFYDLVIVGG
HHHHHCCCCHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCHHHCCCEEEEEEECC
GPAGLAAAVYGASEGLRTVMIEREAPGGQAGTSSRIENYLGFPVGLSGSDLARRAVTQAK
CCHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHH
RFGVEILTPQAGQSLRTENNYHFLTLSDGSEISSHALILALGVSWRRLNMPGIEQFTGAG
HCCEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCEEECCCCCHHHHCCCC
VYYGAAQTEAAACTNEEVYVVGGANSAGQAAMYFSKFAKTVRILVRGESLTKSMSQYLID
EEECCCCCHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHH
QIDGTDNIEVLPFHSVVEAQGSEKLERILVKDSQTDEMKTFETNSLFIFIGATPSTDWLG
HCCCCCCEEEEECHHHHHHCCHHHHHHHHHCCCCCCCCEEEECCEEEEEEECCCCCCCCC
DQVYRDQRGFICTGPDVDTSLGWPLERDRFLLETNVPGIFAVGDVRHNSIKRVASGVGEG
HHHHHCCCCEEEECCCCCCCCCCCCCCCCEEEEECCCCEEEECCCCHHHHHHHHHCCCCC
SICVQFVHRHLANL
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA