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The map label for this gene is tcrA [H]

Identifier: 158336379

GI number: 158336379

Start: 3278743

End: 3279117

Strand: Direct

Name: tcrA [H]

Synonym: AM1_3241

Alternate gene names: 158336379

Gene position: 3278743-3279117 (Clockwise)

Preceding gene: 158336376

Following gene: 158336380

Centisome position: 50.41

GC content: 48.8

Gene sequence:

>375_bases
ATGCGAATCCTGCTGGTAGAAAATGAAGGAGATTTGGGACAGGCAATTAAACAAGTGCTGGTCGGCGAAAAGTATGTGGT
GGACTGGGTGACTGATGGGGCACAAGCGTGGCACTGTTTAGAAAGCCGGTGGACGGATTACACGGTTGCCATTTTTGATT
GGCTGCTGCCAGAACTCTCGGGTTTAGAGCTATGTCAGCGACTTAGAGACCGCCAAAATCCACTTCCCATTTTGATGTTG
ACTGCTTTGGGGCAACCTGAAAATCGCATTGCTGGCCTGGATGCTGGGGCCGACGATTATTTGATGAAGCCCTTCATCAT
GGAAGAACTGCTAGCAAGACTGCGAGCCTTACATTTCTTGATCTATCAAGGCTAA

Upstream 100 bases:

>100_bases
CTTGAGTTTGGATTCAGTTGGGATTGTGCTGAGTAGATGAAAACCAGATGAAATGACAATAGTCTCAGTAGAATCGGCTT
CATGGTCAGGAGCTGAGACA

Downstream 100 bases:

>100_bases
ACCCATATCTAGCGGTAGTTTGCAAGCTGTGGTTTTTCTGTCAATCGTCTGCAGCGATTTGCTCAAAGAGATTCGGGTGC
TGAACAAGTGCAATTGCTTA

Product: two-component response regulator (CheY)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 124; Mature: 124

Protein sequence:

>124_residues
MRILLVENEGDLGQAIKQVLVGEKYVVDWVTDGAQAWHCLESRWTDYTVAIFDWLLPELSGLELCQRLRDRQNPLPILML
TALGQPENRIAGLDAGADDYLMKPFIMEELLARLRALHFLIYQG

Sequences:

>Translated_124_residues
MRILLVENEGDLGQAIKQVLVGEKYVVDWVTDGAQAWHCLESRWTDYTVAIFDWLLPELSGLELCQRLRDRQNPLPILML
TALGQPENRIAGLDAGADDYLMKPFIMEELLARLRALHFLIYQG
>Mature_124_residues
MRILLVENEGDLGQAIKQVLVGEKYVVDWVTDGAQAWHCLESRWTDYTVAIFDWLLPELSGLELCQRLRDRQNPLPILML
TALGQPENRIAGLDAGADDYLMKPFIMEELLARLRALHFLIYQG

Specific function: Member of the three-protein two-component system HK1/HK2/tcrA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=117, Percent_Identity=41.8803418803419, Blast_Score=97, Evalue=3e-22,
Organism=Escherichia coli, GI1790552, Length=117, Percent_Identity=43.5897435897436, Blast_Score=90, Evalue=5e-20,
Organism=Escherichia coli, GI1789809, Length=116, Percent_Identity=38.7931034482759, Blast_Score=86, Evalue=1e-18,
Organism=Escherichia coli, GI87082012, Length=116, Percent_Identity=39.6551724137931, Blast_Score=81, Evalue=2e-17,
Organism=Escherichia coli, GI1789402, Length=117, Percent_Identity=41.025641025641, Blast_Score=80, Evalue=4e-17,
Organism=Escherichia coli, GI1786599, Length=118, Percent_Identity=36.4406779661017, Blast_Score=77, Evalue=4e-16,
Organism=Escherichia coli, GI1787375, Length=117, Percent_Identity=39.3162393162393, Blast_Score=75, Evalue=1e-15,
Organism=Escherichia coli, GI1788394, Length=116, Percent_Identity=36.2068965517241, Blast_Score=72, Evalue=1e-14,
Organism=Escherichia coli, GI1790860, Length=113, Percent_Identity=37.1681415929204, Blast_Score=68, Evalue=2e-13,
Organism=Escherichia coli, GI2367329, Length=116, Percent_Identity=36.2068965517241, Blast_Score=67, Evalue=5e-13,
Organism=Escherichia coli, GI1790863, Length=115, Percent_Identity=38.2608695652174, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1788713, Length=94, Percent_Identity=38.2978723404255, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1786911, Length=113, Percent_Identity=36.283185840708, Blast_Score=60, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 14198; Mature: 14198

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLVENEGDLGQAIKQVLVGEKYVVDWVTDGAQAWHCLESRWTDYTVAIFDWLLPELS
CEEEEEECCCCHHHHHHHHHCCCHHEEEEHHCCHHHHHHHHHCCCCHHHHHHHHHHHCCC
GLELCQRLRDRQNPLPILMLTALGQPENRIAGLDAGADDYLMKPFIMEELLARLRALHFL
HHHHHHHHHHCCCCCCEEEEEECCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
IYQG
HCCC
>Mature Secondary Structure
MRILLVENEGDLGQAIKQVLVGEKYVVDWVTDGAQAWHCLESRWTDYTVAIFDWLLPELS
CEEEEEECCCCHHHHHHHHHCCCHHEEEEHHCCHHHHHHHHHCCCCHHHHHHHHHHHCCC
GLELCQRLRDRQNPLPILMLTALGQPENRIAGLDAGADDYLMKPFIMEELLARLRALHFL
HHHHHHHHHHCCCCCCEEEEEECCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
IYQG
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]