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The map label for this gene is mshA [H]

Identifier: 158336333

GI number: 158336333

Start: 3233801

End: 3235069

Strand: Reverse

Name: mshA [H]

Synonym: AM1_3195

Alternate gene names: 158336333

Gene position: 3235069-3233801 (Counterclockwise)

Preceding gene: 158336344

Following gene: 158336332

Centisome position: 49.74

GC content: 51.06

Gene sequence:

>1269_bases
ATGAGTCCATTTACTCCAATCTCACCCCATGGACCGCCAACCAAAGTTGCACTGATTTCTGTACATGGTGATCCTGCAGT
TGAGATCGGTGCAGAAGAAGCAGGAGGCCAAAATGTTTACGTCCGCCAAGTGGGTGAAGCGCTAGCTCATCTCGGCTGGC
AGGTAGATATGTTTACCCGCAAGGCTCATCCCCAGCAAGCTGAGCAGGTCCAACATTGTCCCGGTTGTCGCACAATTCGC
CTCACTGCTGGCCCCACTGAATTTGTGAGTCGGGATGAAATCTTCGAGTATTTACCACAATTTGTCAGAGAACTCCTAGG
GTTTCAACAGCAAGAAAGCTGTCAATACCCTTTGGTGCACACGAATTATTGGCTGTCCAGCTGGGTCGGCATGGAACTAA
AACAGCACCAACCTCTAGTTCAAATGCATACTTACCACTCCCTAGGGGCGATCAAGTATGCCAATGTTCCCAATATTCCT
GCCATTGCGACGACTCGGCTCGCGATCGAAAAGCAGTGCTTAGAAGCTGCGGACTGTATTGTGGCCACGAGTCCCCAGGA
AGAAGCCCATATGCGATCGCATCTTTCATCCCGTGGCAATATTCAAGTCATTCCCTGTGGCACCGACATTGGTCGCTATG
GAGCGATGACCCGAGCCGAGGCCCGCCAAAAGTTGGGAATTCCCCTAGACGCTAAAGTCGTCTTCTATATTGGTCGCTTT
GACCCTCGCAAAGGCATTGAAACCCTCGTCCGAGCCGTGGCTCAGTCTAAATTTAGGACAGATGACACCTTACAATTGAT
TATTGGGGGCGGTAGTCGTCCGGGAGAAAAAGATGGTTGGGAACGCGATCGCATCGAAGGTATCGTTCAAGACCTCGATC
TGGCCGACCATACACAATTCCCGGGGCGAATTAGCAATGACGCCTTGCCCTACTACTATGCAGCAGCTGATGTCAGTGTC
GTTCCGAGTCACTATGAACCCTTTGGCCTAGTTGCCATAGAATCAATGGCTAGCCGAACACCCGTGATTGCCAGCGATGT
AGGGGGGCTGCAGTTCACCGTTCTACCCCATGAAACGGGCTTACTCATCCCGGCCAAAGATATTCCTGGATTTTCCCGAG
CCATTGATCAAATTTTGGCAGATCCCTCTCTCAGAGAACAATGGGGACTCGCCGCCCGCAAACGAGTAGAAACAACTTTT
AGCTGGCAAGGTGTAGCCCAGCAGTTGAGCCAACTCTATCAACAGCATATTTTGCAAATGACCGCCTAA

Upstream 100 bases:

>100_bases
AGGGATGGTTGTAGGCTATGCTTTGTATAAATATTTATTGATTTATTTTGCAAATTTTGGAAGTATTCTTGCTAAGTGTT
ACTTAGTTCTGCGCAGGGTC

Downstream 100 bases:

>100_bases
AACGGTTACGCTTCCAGCGATCCACACCCATTTTTTGGCGTCCCCGCCATTGTTATACGAAACTTATACCTATTTTTATT
TGGCAAAAACATGTTTGCAT

Product: glycosyl transferase, group 1 family protein

Products: NA

Alternate protein names: N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase; GlcNAc-Ins-P N-acetylglucosaminyltransferase [H]

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MSPFTPISPHGPPTKVALISVHGDPAVEIGAEEAGGQNVYVRQVGEALAHLGWQVDMFTRKAHPQQAEQVQHCPGCRTIR
LTAGPTEFVSRDEIFEYLPQFVRELLGFQQQESCQYPLVHTNYWLSSWVGMELKQHQPLVQMHTYHSLGAIKYANVPNIP
AIATTRLAIEKQCLEAADCIVATSPQEEAHMRSHLSSRGNIQVIPCGTDIGRYGAMTRAEARQKLGIPLDAKVVFYIGRF
DPRKGIETLVRAVAQSKFRTDDTLQLIIGGGSRPGEKDGWERDRIEGIVQDLDLADHTQFPGRISNDALPYYYAAADVSV
VPSHYEPFGLVAIESMASRTPVIASDVGGLQFTVLPHETGLLIPAKDIPGFSRAIDQILADPSLREQWGLAARKRVETTF
SWQGVAQQLSQLYQQHILQMTA

Sequences:

>Translated_422_residues
MSPFTPISPHGPPTKVALISVHGDPAVEIGAEEAGGQNVYVRQVGEALAHLGWQVDMFTRKAHPQQAEQVQHCPGCRTIR
LTAGPTEFVSRDEIFEYLPQFVRELLGFQQQESCQYPLVHTNYWLSSWVGMELKQHQPLVQMHTYHSLGAIKYANVPNIP
AIATTRLAIEKQCLEAADCIVATSPQEEAHMRSHLSSRGNIQVIPCGTDIGRYGAMTRAEARQKLGIPLDAKVVFYIGRF
DPRKGIETLVRAVAQSKFRTDDTLQLIIGGGSRPGEKDGWERDRIEGIVQDLDLADHTQFPGRISNDALPYYYAAADVSV
VPSHYEPFGLVAIESMASRTPVIASDVGGLQFTVLPHETGLLIPAKDIPGFSRAIDQILADPSLREQWGLAARKRVETTF
SWQGVAQQLSQLYQQHILQMTA
>Mature_421_residues
SPFTPISPHGPPTKVALISVHGDPAVEIGAEEAGGQNVYVRQVGEALAHLGWQVDMFTRKAHPQQAEQVQHCPGCRTIRL
TAGPTEFVSRDEIFEYLPQFVRELLGFQQQESCQYPLVHTNYWLSSWVGMELKQHQPLVQMHTYHSLGAIKYANVPNIPA
IATTRLAIEKQCLEAADCIVATSPQEEAHMRSHLSSRGNIQVIPCGTDIGRYGAMTRAEARQKLGIPLDAKVVFYIGRFD
PRKGIETLVRAVAQSKFRTDDTLQLIIGGGSRPGEKDGWERDRIEGIVQDLDLADHTQFPGRISNDALPYYYAAADVSVV
PSHYEPFGLVAIESMASRTPVIASDVGGLQFTVLPHETGLLIPAKDIPGFSRAIDQILADPSLREQWGLAARKRVETTFS
WQGVAQQLSQLYQQHILQMTA

Specific function: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family. MshA subfamily [H]

Homologues:

Organism=Homo sapiens, GI14861836, Length=250, Percent_Identity=27.2, Blast_Score=70, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR017814 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.250 [H]

Molecular weight: Translated: 46708; Mature: 46576

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPFTPISPHGPPTKVALISVHGDPAVEIGAEEAGGQNVYVRQVGEALAHLGWQVDMFTR
CCCCCCCCCCCCCCEEEEEEECCCCCEEECCCCCCCCEEHHHHHHHHHHHCCCEEEEHHH
KAHPQQAEQVQHCPGCRTIRLTAGPTEFVSRDEIFEYLPQFVRELLGFQQQESCQYPLVH
CCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEE
TNYWLSSWVGMELKQHQPLVQMHTYHSLGAIKYANVPNIPAIATTRLAIEKQCLEAADCI
CCHHHHHHHCCHHHHCCCHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCEE
VATSPQEEAHMRSHLSSRGNIQVIPCGTDIGRYGAMTRAEARQKLGIPLDAKVVFYIGRF
EECCCHHHHHHHHHHCCCCCEEEEECCCCHHHHCCHHHHHHHHHCCCCCCCEEEEEEECC
DPRKGIETLVRAVAQSKFRTDDTLQLIIGGGSRPGEKDGWERDRIEGIVQDLDLADHTQF
CHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
PGRISNDALPYYYAAADVSVVPSHYEPFGLVAIESMASRTPVIASDVGGLQFTVLPHETG
CCCCCCCCCCEEEEECCCEECCCCCCCCHHHHHHHHHCCCCEEEECCCCEEEEEEECCCC
LLIPAKDIPGFSRAIDQILADPSLREQWGLAARKRVETTFSWQGVAQQLSQLYQQHILQM
CEEECCCCCCHHHHHHHHHCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TA
CC
>Mature Secondary Structure 
SPFTPISPHGPPTKVALISVHGDPAVEIGAEEAGGQNVYVRQVGEALAHLGWQVDMFTR
CCCCCCCCCCCCCEEEEEEECCCCCEEECCCCCCCCEEHHHHHHHHHHHCCCEEEEHHH
KAHPQQAEQVQHCPGCRTIRLTAGPTEFVSRDEIFEYLPQFVRELLGFQQQESCQYPLVH
CCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEE
TNYWLSSWVGMELKQHQPLVQMHTYHSLGAIKYANVPNIPAIATTRLAIEKQCLEAADCI
CCHHHHHHHCCHHHHCCCHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCEE
VATSPQEEAHMRSHLSSRGNIQVIPCGTDIGRYGAMTRAEARQKLGIPLDAKVVFYIGRF
EECCCHHHHHHHHHHCCCCCEEEEECCCCHHHHCCHHHHHHHHHCCCCCCCEEEEEEECC
DPRKGIETLVRAVAQSKFRTDDTLQLIIGGGSRPGEKDGWERDRIEGIVQDLDLADHTQF
CHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
PGRISNDALPYYYAAADVSVVPSHYEPFGLVAIESMASRTPVIASDVGGLQFTVLPHETG
CCCCCCCCCCEEEEECCCEECCCCCCCCHHHHHHHHHCCCCEEEECCCCEEEEEEECCCC
LLIPAKDIPGFSRAIDQILADPSLREQWGLAARKRVETTFSWQGVAQQLSQLYQQHILQM
CEEECCCCCCHHHHHHHHHCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA