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The map label for this gene is hlyD [H]

Identifier: 158336321

GI number: 158336321

Start: 3213896

End: 3215491

Strand: Direct

Name: hlyD [H]

Synonym: AM1_3183

Alternate gene names: 158336321

Gene position: 3213896-3215491 (Clockwise)

Preceding gene: 158336320

Following gene: 158336328

Centisome position: 49.42

GC content: 46.43

Gene sequence:

>1596_bases
ATGACCAGTACTCAAGATTTCGCTGGCGACCCCACCAAACTGAATGGGACGAATGGAAATAACGGCAATGGATCTGAGCC
AACGGTCCTGTCCCTGACTAAATCAGAGCCCAAAAAAGAAAAACCCTTTGATCGGCCAGTTATTCTGCAGCAATCTCCGT
TTTGGTCTAGAGCCATCATTTATGGAATTGTAGGGGCGGCTGCAGCAGCATTGGCATGGGCCTGCTTGTTTGAAATTGAA
GAAGCTATTCCTGCCACGGGACAGCTCGAACCCAAGGGGGCCGTTAAGGCTGTACAATCCCCTGTGACTGGTGTGGTTAA
AGAGATTAAGGTCGAAGAAGGAGACCTGGTGAAGAAAGGGGACGTTTTAATTGTTCTCAATCGTAAAGCAACGCGATCAG
AGATCAATTCCCTAAAACGCCAGCGTCGTAACCTAGTGCAAGTCAACGAGTATTATCGCCAACAGCTGAAAGGACAAACC
GATACCCCCTTGCCGGATTTAATTGATCCCGAGTTGATTAATTCCACCCGCGATCGCCAATCTTTAGTGGCGGAAAATAA
ATTATTTAGAGCCCAGCTGAATGGTGCTAATAATGCTCAAGCCTTTTCCGCAGAAGAGCGGCAGCGTTTAAATTCAGGTC
TGCTGCAAGGAAAAACAAGCGTGGCGGCTGCCCAAGCCCGAGTCATGCAAGGGGATAAACAGCTTCGCCAAATTGAGGTC
CAGCTAGAACAGACCAAAATTCAGCTGGCGAGTGCCCAACAGACTTTAGCCCTCAACAAAGAAATTGTCGCAGATATTGA
AGATGCCCATAAGAAAGGGGCTATTGCTCGGGTTCAATTCAAGCGCCAAGAAGATGAAGTGCAGTCTGGTGAAGCCGAGG
TCTCTCGCTTACAACAGGAACAGATTCGCCTCTTGCGGCAAATGGAGCAGATTGGACAAGAAAAACTACAGTCTCAAGCC
CAAGCGCTTAATACGGTAGCGACGAATCAGCGAGATTTACTAGACCGAATCGCCGCTAATCAACAGCGTATTACTGAAAT
TGACAGTCAGCTGACCAAGGCCATTGTCGATAATCAGAGAACCATCGCTGATCTTGAAAATCGGCTACAGCAAGCAGAAT
TAACCCTGGATTACCAAGAGCTGAAAGCACCAGTCGCTGGGGTTGTGTTTGATTTGCAGCCCAGTTCACCGGGCTTTGTG
GCAAATGCGAGTGAACCCATTTTAAAAATTGTCCCTGAGGATAATTTGAAAGCCAAAGTTTACATTACCAATAAAGATAT
TGGCTTTATCCAGACTGGTATGCCTGTAGATGTCAGAGTAGATTCCTATAACTTTAGTGAATTTGGTGACATTAAAGGCA
CCATTGAATCCATTGGCTCAGATGCCTTGCCTCCTACAGAAGTGCGACAGTTTTATAGTTTTCCCGCCGTTGTTAAATTA
GATACTCAAACTTTGAAGACCAGGGGCCGCCGTGAATTAGACTTGCAATCTGGAATGTCGGTCAGTGTCAATATCAAAGT
CCGCGATCGACCGATTATTAGCTTGATTACTGATCGCTTTTCCAGAGAAGAGGATGGCATTAAGCATTTGCGCTAA

Upstream 100 bases:

>100_bases
TGATGGATCAGGGCAATCTAGTAGAACAAGGTACCCATGCTGAATTGATGCAGCAAAAAGGTCGATATTACTGGCTATAC
CAGCAACAGGAGATTCAATC

Downstream 100 bases:

>100_bases
GTCATAAAAGTCTCGGCTGAGTAGCCCCTGGTGACGAGATCAGTGAGTCAAATAAAAACCCTAACGAAATACCGTTAGGG
CCAAGAGATCGATATTGGAT

Product: HlyD family secretion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 531; Mature: 530

Protein sequence:

>531_residues
MTSTQDFAGDPTKLNGTNGNNGNGSEPTVLSLTKSEPKKEKPFDRPVILQQSPFWSRAIIYGIVGAAAAALAWACLFEIE
EAIPATGQLEPKGAVKAVQSPVTGVVKEIKVEEGDLVKKGDVLIVLNRKATRSEINSLKRQRRNLVQVNEYYRQQLKGQT
DTPLPDLIDPELINSTRDRQSLVAENKLFRAQLNGANNAQAFSAEERQRLNSGLLQGKTSVAAAQARVMQGDKQLRQIEV
QLEQTKIQLASAQQTLALNKEIVADIEDAHKKGAIARVQFKRQEDEVQSGEAEVSRLQQEQIRLLRQMEQIGQEKLQSQA
QALNTVATNQRDLLDRIAANQQRITEIDSQLTKAIVDNQRTIADLENRLQQAELTLDYQELKAPVAGVVFDLQPSSPGFV
ANASEPILKIVPEDNLKAKVYITNKDIGFIQTGMPVDVRVDSYNFSEFGDIKGTIESIGSDALPPTEVRQFYSFPAVVKL
DTQTLKTRGRRELDLQSGMSVSVNIKVRDRPIISLITDRFSREEDGIKHLR

Sequences:

>Translated_531_residues
MTSTQDFAGDPTKLNGTNGNNGNGSEPTVLSLTKSEPKKEKPFDRPVILQQSPFWSRAIIYGIVGAAAAALAWACLFEIE
EAIPATGQLEPKGAVKAVQSPVTGVVKEIKVEEGDLVKKGDVLIVLNRKATRSEINSLKRQRRNLVQVNEYYRQQLKGQT
DTPLPDLIDPELINSTRDRQSLVAENKLFRAQLNGANNAQAFSAEERQRLNSGLLQGKTSVAAAQARVMQGDKQLRQIEV
QLEQTKIQLASAQQTLALNKEIVADIEDAHKKGAIARVQFKRQEDEVQSGEAEVSRLQQEQIRLLRQMEQIGQEKLQSQA
QALNTVATNQRDLLDRIAANQQRITEIDSQLTKAIVDNQRTIADLENRLQQAELTLDYQELKAPVAGVVFDLQPSSPGFV
ANASEPILKIVPEDNLKAKVYITNKDIGFIQTGMPVDVRVDSYNFSEFGDIKGTIESIGSDALPPTEVRQFYSFPAVVKL
DTQTLKTRGRRELDLQSGMSVSVNIKVRDRPIISLITDRFSREEDGIKHLR
>Mature_530_residues
TSTQDFAGDPTKLNGTNGNNGNGSEPTVLSLTKSEPKKEKPFDRPVILQQSPFWSRAIIYGIVGAAAAALAWACLFEIEE
AIPATGQLEPKGAVKAVQSPVTGVVKEIKVEEGDLVKKGDVLIVLNRKATRSEINSLKRQRRNLVQVNEYYRQQLKGQTD
TPLPDLIDPELINSTRDRQSLVAENKLFRAQLNGANNAQAFSAEERQRLNSGLLQGKTSVAAAQARVMQGDKQLRQIEVQ
LEQTKIQLASAQQTLALNKEIVADIEDAHKKGAIARVQFKRQEDEVQSGEAEVSRLQQEQIRLLRQMEQIGQEKLQSQAQ
ALNTVATNQRDLLDRIAANQQRITEIDSQLTKAIVDNQRTIADLENRLQQAELTLDYQELKAPVAGVVFDLQPSSPGFVA
NASEPILKIVPEDNLKAKVYITNKDIGFIQTGMPVDVRVDSYNFSEFGDIKGTIESIGSDALPPTEVRQFYSFPAVVKLD
TQTLKTRGRRELDLQSGMSVSVNIKVRDRPIISLITDRFSREEDGIKHLR

Specific function: Involved in the transport of hemolysin A [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 58953; Mature: 58821

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSTQDFAGDPTKLNGTNGNNGNGSEPTVLSLTKSEPKKEKPFDRPVILQQSPFWSRAII
CCCCCCCCCCCCEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEECCCCHHHHHH
YGIVGAAAAALAWACLFEIEEAIPATGQLEPKGAVKAVQSPVTGVVKEIKVEEGDLVKKG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECC
DVLIVLNRKATRSEINSLKRQRRNLVQVNEYYRQQLKGQTDTPLPDLIDPELINSTRDRQ
CEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCHHHH
SLVAENKLFRAQLNGANNAQAFSAEERQRLNSGLLQGKTSVAAAQARVMQGDKQLRQIEV
HHHHHHHHHEEECCCCCCCHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
QLEQTKIQLASAQQTLALNKEIVADIEDAHKKGAIARVQFKRQEDEVQSGEAEVSRLQQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHCCHHHHHHHHHH
QIRLLRQMEQIGQEKLQSQAQALNTVATNQRDLLDRIAANQQRITEIDSQLTKAIVDNQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCH
TIADLENRLQQAELTLDYQELKAPVAGVVFDLQPSSPGFVANASEPILKIVPEDNLKAKV
HHHHHHHHHHHHHHEECHHHHCCCCEEEEEEECCCCCCEEECCCCCEEEECCCCCCEEEE
YITNKDIGFIQTGMPVDVRVDSYNFSEFGDIKGTIESIGSDALPPTEVRQFYSFPAVVKL
EEECCCCCEEECCCCEEEEECCCCCCHHCCHHHHHHHCCCCCCCHHHHHHHHCCCCEEEE
DTQTLKTRGRRELDLQSGMSVSVNIKVRDRPIISLITDRFSREEDGIKHLR
CHHHHHHCCCCEEHHHCCCEEEEEEEECCCCHHHHHHHHHCCCCCHHHCCC
>Mature Secondary Structure 
TSTQDFAGDPTKLNGTNGNNGNGSEPTVLSLTKSEPKKEKPFDRPVILQQSPFWSRAII
CCCCCCCCCCCEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEECCCCHHHHHH
YGIVGAAAAALAWACLFEIEEAIPATGQLEPKGAVKAVQSPVTGVVKEIKVEEGDLVKKG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECC
DVLIVLNRKATRSEINSLKRQRRNLVQVNEYYRQQLKGQTDTPLPDLIDPELINSTRDRQ
CEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCHHHH
SLVAENKLFRAQLNGANNAQAFSAEERQRLNSGLLQGKTSVAAAQARVMQGDKQLRQIEV
HHHHHHHHHEEECCCCCCCHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
QLEQTKIQLASAQQTLALNKEIVADIEDAHKKGAIARVQFKRQEDEVQSGEAEVSRLQQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHCCHHHHHHHHHH
QIRLLRQMEQIGQEKLQSQAQALNTVATNQRDLLDRIAANQQRITEIDSQLTKAIVDNQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCH
TIADLENRLQQAELTLDYQELKAPVAGVVFDLQPSSPGFVANASEPILKIVPEDNLKAKV
HHHHHHHHHHHHHHEECHHHHCCCCEEEEEEECCCCCCEEECCCCCEEEECCCCCCEEEE
YITNKDIGFIQTGMPVDVRVDSYNFSEFGDIKGTIESIGSDALPPTEVRQFYSFPAVVKL
EEECCCCCEEECCCCEEEEECCCCCCHHCCHHHHHHHCCCCCCCHHHHHHHHCCCCEEEE
DTQTLKTRGRRELDLQSGMSVSVNIKVRDRPIISLITDRFSREEDGIKHLR
CHHHHHHCCCCEEHHHCCCEEEEEEEECCCCHHHHHHHHHCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3891743; 1495479 [H]