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The map label for this gene is aroE [H]

Identifier: 158336295

GI number: 158336295

Start: 3187183

End: 3188061

Strand: Reverse

Name: aroE [H]

Synonym: AM1_3157

Alternate gene names: 158336295

Gene position: 3188061-3187183 (Counterclockwise)

Preceding gene: 158336296

Following gene: 158336294

Centisome position: 49.02

GC content: 52.9

Gene sequence:

>879_bases
ATGGTTCAGATTACGGGTGCCACAAAGTTGTTGGGCGTCATGGGTCATCCCGTGGAACATTCTTTATCCCCAGTGATGCA
CAATGCCGCCCTCCAAGCGTTAGCGACCCAGCAACACCGTTTTCTGGAGTATGTCTACATCCCTTTGCCGGTGACCGCTC
ATGCCCTCCCTGCTGTGGTCTCCAGCTTAAGGGAGCTGGGATGCTGTGGTTTTAATATCACGATCCCCCACAAGCAAGCG
ATTATGCCTTTGCTGACGGAAACGACCGCCATCGCCAAAGCAGTGGGCGCTGTCAATACCGTTTGGCCCACCGATGACGG
CTGGGCAGGCACTAACACGGATGTGGAAGGATTTTTATCCCCTTTACAGCCCCTCAATCGGGATTGGTCGACCATCACCC
CTTGCATCTTAGGATGTGGTGGCGCTGCCCGAGCGGTGTTAGCCGGCTGTGCTCAGCTCGGTTGTCTCCAGGTTCATATC
ATTGGCCGTCAACCTGCCAAGTTAGAACACCTCAAATCAACTTGCGCCACTACCCTATCCATTGATATTCAAATTCATCT
GTGGGAAGATCTTGCCCCTCTATTACCCCAAGCTGCTTTGCTGATCAATACCACGCCGGTCGGCATGTCTCCTCATATCC
AAGCCTCGCCTCTTTCCGCAGTAGAGATTGATCAGTTGCCCAAAGAGGCCATTGTCTATGATTTGATTTACACTCCCAAT
CCCACGGTATTGCTGAAACAAACCCAAGCCAGTGGCCGCATCGCCATCACTGGGGTAGAGATGCTGGTACAGCAAGGGGC
TGCAGCTTTATCTCTATGGATCGATCAACCCGCTCCTGTGGACATTATGCGAGAGGCACTGCTGGCCTGTTTTACTTAG

Upstream 100 bases:

>100_bases
GCATTCGGACTGGCGAAAAGGATTTTGAAGCCGTCTAGCCTGATAGACGTGCCTTTAATGCACCTGCAAGTCAAAATGCA
AAAGTAGCGATTGCCAAGAC

Downstream 100 bases:

>100_bases
GTTATTGGCAAGCCCAGCACAACCATTTAATTCTCCAAACAGGGTAAAATTAGCTGCATTAGACTTTATTCGCGAAAAAA
TCAGCAAATTCTTTTACTTA

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MVQITGATKLLGVMGHPVEHSLSPVMHNAALQALATQQHRFLEYVYIPLPVTAHALPAVVSSLRELGCCGFNITIPHKQA
IMPLLTETTAIAKAVGAVNTVWPTDDGWAGTNTDVEGFLSPLQPLNRDWSTITPCILGCGGAARAVLAGCAQLGCLQVHI
IGRQPAKLEHLKSTCATTLSIDIQIHLWEDLAPLLPQAALLINTTPVGMSPHIQASPLSAVEIDQLPKEAIVYDLIYTPN
PTVLLKQTQASGRIAITGVEMLVQQGAAALSLWIDQPAPVDIMREALLACFT

Sequences:

>Translated_292_residues
MVQITGATKLLGVMGHPVEHSLSPVMHNAALQALATQQHRFLEYVYIPLPVTAHALPAVVSSLRELGCCGFNITIPHKQA
IMPLLTETTAIAKAVGAVNTVWPTDDGWAGTNTDVEGFLSPLQPLNRDWSTITPCILGCGGAARAVLAGCAQLGCLQVHI
IGRQPAKLEHLKSTCATTLSIDIQIHLWEDLAPLLPQAALLINTTPVGMSPHIQASPLSAVEIDQLPKEAIVYDLIYTPN
PTVLLKQTQASGRIAITGVEMLVQQGAAALSLWIDQPAPVDIMREALLACFT
>Mature_292_residues
MVQITGATKLLGVMGHPVEHSLSPVMHNAALQALATQQHRFLEYVYIPLPVTAHALPAVVSSLRELGCCGFNITIPHKQA
IMPLLTETTAIAKAVGAVNTVWPTDDGWAGTNTDVEGFLSPLQPLNRDWSTITPCILGCGGAARAVLAGCAQLGCLQVHI
IGRQPAKLEHLKSTCATTLSIDIQIHLWEDLAPLLPQAALLINTTPVGMSPHIQASPLSAVEIDQLPKEAIVYDLIYTPN
PTVLLKQTQASGRIAITGVEMLVQQGAAALSLWIDQPAPVDIMREALLACFT

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:
GO:0004764: Shikimate 5-dehydrogenase, putative
GO:0005488: Shikimate 5-dehydrogenase, putative
GO:0005737: Shikimate 5-dehydrogenase, putative
GO:0009073: Shikimate 5-dehydrogenase, putative
GO:0016491: Shikimate 5-dehydrogenase, putative
GO:0055114: Shikimate 5-dehydrogenase, putative

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=296, Percent_Identity=29.3918918918919, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1789675, Length=270, Percent_Identity=32.2222222222222, Blast_Score=89, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6320332, Length=294, Percent_Identity=26.8707482993197, Blast_Score=80, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 31111; Mature: 31111

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQITGATKLLGVMGHPVEHSLSPVMHNAALQALATQQHRFLEYVYIPLPVTAHALPAVV
CEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHH
SSLRELGCCGFNITIPHKQAIMPLLTETTAIAKAVGAVNTVWPTDDGWAGTNTDVEGFLS
HHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHH
PLQPLNRDWSTITPCILGCGGAARAVLAGCAQLGCLQVHIIGRQPAKLEHLKSTCATTLS
HHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHEEEE
IDIQIHLWEDLAPLLPQAALLINTTPVGMSPHIQASPLSAVEIDQLPKEAIVYDLIYTPN
EEEEEEEHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHCCHHHEEEEEEECCC
PTVLLKQTQASGRIAITGVEMLVQQGAAALSLWIDQPAPVDIMREALLACFT
CCEEEEECCCCCCEEEHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MVQITGATKLLGVMGHPVEHSLSPVMHNAALQALATQQHRFLEYVYIPLPVTAHALPAVV
CEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHH
SSLRELGCCGFNITIPHKQAIMPLLTETTAIAKAVGAVNTVWPTDDGWAGTNTDVEGFLS
HHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHH
PLQPLNRDWSTITPCILGCGGAARAVLAGCAQLGCLQVHIIGRQPAKLEHLKSTCATTLS
HHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHEEEE
IDIQIHLWEDLAPLLPQAALLINTTPVGMSPHIQASPLSAVEIDQLPKEAIVYDLIYTPN
EEEEEEEHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHCCHHHEEEEEEECCC
PTVLLKQTQASGRIAITGVEMLVQQGAAALSLWIDQPAPVDIMREALLACFT
CCEEEEECCCCCCEEEHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA