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The map label for this gene is 158336285

Identifier: 158336285

GI number: 158336285

Start: 3176167

End: 3176580

Strand: Reverse

Name: 158336285

Synonym: AM1_3146

Alternate gene names: NA

Gene position: 3176580-3176167 (Counterclockwise)

Preceding gene: 158336286

Following gene: 158336283

Centisome position: 48.84

GC content: 46.62

Gene sequence:

>414_bases
ATGTACACACGTACCGTTCGTCTCCAAGATACTGATGCTGCGGGGGTAGTCTATTTCACCAGCGCCCTTGATATCTGTCA
TGAAGCCTTTGAAGATTCTCTGATGGGAGCGGGGATTGATATTCGTACATTCTTTAGCAACCCAGATACGGCAACGCCAA
TCATCCATGCCGATATTGATTTTCTCAAGCCCAGTTTTTGTGGCGATCAGTTAACCCTTCAACTGAGTACTCACCAACTC
GCTGAAGATGAATTTGAAGTTCGCTACAACATTACAGCGGTGAATAAAGGGGAACGTCTGATTGCCAAGGCGACGATTCG
GCATGTATGTATTAATCCCATTAATCGGCAACGCCAGCCCCTACCAAAAGAATTGGTGACCTGGATTCAGCGATGGAGTC
TAGCCATGAGCTAA

Upstream 100 bases:

>100_bases
GCTAATATCTAAATTCTCTTTCTTTGCCAGAAAATATGCACTGATCAAGAGGGGACCATCTGTGTCTATCCTCTTAATAT
TCAGTTTTATACAGTGGCCC

Downstream 100 bases:

>100_bases
GGGCAGAGAAGTAGAGAGAAGCGCTGCAGGCTGAAAACTCGTCAATACTTCGGGTGTACTGGCTCTATGCTTTGCACCAA
TAGAGGTCTGGTAACAACGC

Product: thioesterase

Products: NA

Alternate protein names: DHNA-CoA hydrolase; DHNA-CoA thioesterase

Number of amino acids: Translated: 137; Mature: 137

Protein sequence:

>137_residues
MYTRTVRLQDTDAAGVVYFTSALDICHEAFEDSLMGAGIDIRTFFSNPDTATPIIHADIDFLKPSFCGDQLTLQLSTHQL
AEDEFEVRYNITAVNKGERLIAKATIRHVCINPINRQRQPLPKELVTWIQRWSLAMS

Sequences:

>Translated_137_residues
MYTRTVRLQDTDAAGVVYFTSALDICHEAFEDSLMGAGIDIRTFFSNPDTATPIIHADIDFLKPSFCGDQLTLQLSTHQL
AEDEFEVRYNITAVNKGERLIAKATIRHVCINPINRQRQPLPKELVTWIQRWSLAMS
>Mature_137_residues
MYTRTVRLQDTDAAGVVYFTSALDICHEAFEDSLMGAGIDIRTFFSNPDTATPIIHADIDFLKPSFCGDQLTLQLSTHQL
AEDEFEVRYNITAVNKGERLIAKATIRHVCINPINRQRQPLPKELVTWIQRWSLAMS

Specific function: Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl- CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis

COG id: COG0824

COG function: function code R; Predicted thioesterase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. DHNA-CoA hydrolase subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DNCH_ACAM1 (B0CEN8)

Other databases:

- EMBL:   CP000828
- RefSeq:   YP_001517459.1
- ProteinModelPortal:   B0CEN8
- SMR:   B0CEN8
- GeneID:   5681955
- GenomeReviews:   CP000828_GR
- KEGG:   amr:AM1_3146
- HOGENOM:   HBG439376
- OMA:   HEAWEES
- BioCyc:   AMAR329726:AM1_3146-MONOMER
- HAMAP:   MF_02101
- InterPro:   IPR022829
- InterPro:   IPR006683

Pfam domain/function: PF03061 4HBT

EC number: =3.1.2.28

Molecular weight: Translated: 15556; Mature: 15556

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS01328 4HBCOA_THIOESTERASE

Important sites: ACT_SITE 12-12

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTRTVRLQDTDAAGVVYFTSALDICHEAFEDSLMGAGIDIRTFFSNPDTATPIIHADID
CCCEEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEECCCC
FLKPSFCGDQLTLQLSTHQLAEDEFEVRYNITAVNKGERLIAKATIRHVCINPINRQRQP
CCCCCCCCCEEEEEECCHHHCCCCEEEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCC
LPKELVTWIQRWSLAMS
CCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYTRTVRLQDTDAAGVVYFTSALDICHEAFEDSLMGAGIDIRTFFSNPDTATPIIHADID
CCCEEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEECCCC
FLKPSFCGDQLTLQLSTHQLAEDEFEVRYNITAVNKGERLIAKATIRHVCINPINRQRQP
CCCCCCCCCEEEEEECCHHHCCCCEEEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCC
LPKELVTWIQRWSLAMS
CCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA