Click here to switch to the map view.

The map label for this gene is lepB [H]

Identifier: 158336279

GI number: 158336279

Start: 3168180

End: 3168788

Strand: Reverse

Name: lepB [H]

Synonym: AM1_3141

Alternate gene names: 158336279

Gene position: 3168788-3168180 (Counterclockwise)

Preceding gene: 158336280

Following gene: 158336278

Centisome position: 48.72

GC content: 46.8

Gene sequence:

>609_bases
ATGCTGAAAAAGTCATTTTTTTTCTCTACAAAAGTGGGATGGCGAGAAGCAACCAAAACGGTGGGACTCAGCTTGTTGTT
GGCATTTGGTATTCGGTCTTTTGTCGCCGAGGCCCGTTTCATCCCTTCAGGGTCGATGGAGCCAACGCTGCAAATTCACG
ATCGCTTGATTATCGATAAAGTCACTTACCAATTTAATTCCCCTCAACGGGGGGATATTATCGTCTTCCGTCCGCCCCAG
GCTTTACGGCAGCATGTCGATCGACAGGACGCTCCACTCTCCATGGACACGATTATTAAACGTGTGATTGGCATCCCGGG
AGATCAATTAGAGCTTAAAGATGGCGCTGTCTATCGCAATCAGGTCAAGATTCGAGAACAATATGTGGCTCATAAGGCCA
AAACATCTGTTCAAGTCTGTCCACCCTCTCTATCTAAATCCTTTCTAGGATTACCCCAAGTGGTACCTGCAGACCACTAT
CTCGTTCTGGGTGATAATCGTCTCAACAGCTACGATGGCCGCTGTTGGGGATTAGTATCTCGTTCAGATTTATTGGGTCG
AGCAGTCTTTCGCTATTGGCCAGTTCACCGAATTGGAAATTTAGAGTAA

Upstream 100 bases:

>100_bases
TCACTGGTGCTTTTCTCAACGGGTGCTGACGTATCTATTCTCATTCCGATAGGGCAAGCACTACACCCCAATACAGCCAA
GATTCACTTTCTTTCCAGCT

Downstream 100 bases:

>100_bases
GACGGCTGTGATCAAGCACAAGCGCTGACCAGACAGGATTGTGTTATAAATCAACTTACTGGGAAAACTGATTTGTAAGA
CGTAACCCATCCCTATCCTT

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MLKKSFFFSTKVGWREATKTVGLSLLLAFGIRSFVAEARFIPSGSMEPTLQIHDRLIIDKVTYQFNSPQRGDIIVFRPPQ
ALRQHVDRQDAPLSMDTIIKRVIGIPGDQLELKDGAVYRNQVKIREQYVAHKAKTSVQVCPPSLSKSFLGLPQVVPADHY
LVLGDNRLNSYDGRCWGLVSRSDLLGRAVFRYWPVHRIGNLE

Sequences:

>Translated_202_residues
MLKKSFFFSTKVGWREATKTVGLSLLLAFGIRSFVAEARFIPSGSMEPTLQIHDRLIIDKVTYQFNSPQRGDIIVFRPPQ
ALRQHVDRQDAPLSMDTIIKRVIGIPGDQLELKDGAVYRNQVKIREQYVAHKAKTSVQVCPPSLSKSFLGLPQVVPADHY
LVLGDNRLNSYDGRCWGLVSRSDLLGRAVFRYWPVHRIGNLE
>Mature_202_residues
MLKKSFFFSTKVGWREATKTVGLSLLLAFGIRSFVAEARFIPSGSMEPTLQIHDRLIIDKVTYQFNSPQRGDIIVFRPPQ
ALRQHVDRQDAPLSMDTIIKRVIGIPGDQLELKDGAVYRNQVKIREQYVAHKAKTSVQVCPPSLSKSFLGLPQVVPADHY
LVLGDNRLNSYDGRCWGLVSRSDLLGRAVFRYWPVHRIGNLE

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=114, Percent_Identity=35.0877192982456, Blast_Score=61, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 22906; Mature: 22906

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKKSFFFSTKVGWREATKTVGLSLLLAFGIRSFVAEARFIPSGSMEPTLQIHDRLIIDK
CCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHEEEH
VTYQFNSPQRGDIIVFRPPQALRQHVDRQDAPLSMDTIIKRVIGIPGDQLELKDGAVYRN
EEEEECCCCCCCEEEECCCHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCEEECCCCEEHH
QVKIREQYVAHKAKTSVQVCPPSLSKSFLGLPQVVPADHYLVLGDNRLNSYDGRCWGLVS
HHHHHHHHHHHHHCCCEEECCCHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCEEEEECC
RSDLLGRAVFRYWPVHRIGNLE
HHHHHHHHHHHHCCHHHCCCCC
>Mature Secondary Structure
MLKKSFFFSTKVGWREATKTVGLSLLLAFGIRSFVAEARFIPSGSMEPTLQIHDRLIIDK
CCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHEEEH
VTYQFNSPQRGDIIVFRPPQALRQHVDRQDAPLSMDTIIKRVIGIPGDQLELKDGAVYRN
EEEEECCCCCCCEEEECCCHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCEEECCCCEEHH
QVKIREQYVAHKAKTSVQVCPPSLSKSFLGLPQVVPADHYLVLGDNRLNSYDGRCWGLVS
HHHHHHHHHHHHHCCCEEECCCHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCEEEEECC
RSDLLGRAVFRYWPVHRIGNLE
HHHHHHHHHHHHCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7865790 [H]