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The map label for this gene is znuC [C]

Identifier: 158336211

GI number: 158336211

Start: 3097460

End: 3098230

Strand: Direct

Name: znuC [C]

Synonym: AM1_3073

Alternate gene names: 158336211

Gene position: 3097460-3098230 (Clockwise)

Preceding gene: 158336210

Following gene: 158336212

Centisome position: 47.63

GC content: 54.73

Gene sequence:

>771_bases
TTGCCAGAGGCCATTCTGCGGGTTTCAGGACTAACGGTTGTTCGCGACAAGCATGTTGCTGTCGAACAGGTATCGTTTGC
CGTGCAGCCGGGGACTAATGTGGCCATCGTTGGCCCCAATGGCGCGGGAAAGAGTAGCTTGATTCAAGCTGTTCTGGGGG
TACTCCCGCGTCAGGTGGGCCAGGTAGAGGTGCTGGGTCATACCCTGAGTCCCCAAGGCCGACTGCCAACCAAGATTCGG
GATGCGATCGCATATCTACCGCAAAACTTTAGTTTCGATCGCCGGATTCCCATGACCGTCGAAGAAGTGGTGGGCTTAGG
CTGGCATACCCTCGGTCTCCAGTGGCCCTGGACCGGGCATAGAGCGAGACAGATTGCGGTTCGTCAAGCCCTGGGCCAGG
TGGAGGCGCTCCATCTGAAACGAAAACGGATCAGCGATCTATCGGGGGGCGAAACTAAGCGAGTCCTGCTGGCCTATTGT
CTGGTTAGGCCGCGTCGTTTGTTGATTTTAGATGAGGCCCCTGCAGGTCTAGATCTGCGGGCGGAAGCAGAATTCTACCA
ATTGCTGAACCAGCTCAAACAACAGCATGGATGGGCCATTTTACAAGTCTCTCACGATCTGAATATGGTGCAGCGCCAGT
GTGATCATGTGTTGTGTATTAACCGCACGTTACTCTGTGAGGGAGTTCCTGAAGTGGCTCTGTCTAGGGAAAGCTTGAGC
ACAGTCTATGGTCCCGAATTTGCCCGCTATCACCATTCCTGTTCGTTGTAG

Upstream 100 bases:

>100_bases
TTGGTAACCAGCCTCAAGCTTGGGTGCCAGCGCGACCCAGACAACGGACTATCGCAACCTTGCCCCAGTGGGTTCAGGTG
AAATTCTAGGAGGTTCAAAT

Downstream 100 bases:

>100_bases
TTTGTAACCCCATTCCATGCCTCTTGCCAGCGAAATCACTCGAATTATCGACCTGTTTCAGTTTCCGTTTATGCAGCGGG
CAGTGATCAGCGGCATCCTG

Product: zinc ABC transporter ATP-binding protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MPEAILRVSGLTVVRDKHVAVEQVSFAVQPGTNVAIVGPNGAGKSSLIQAVLGVLPRQVGQVEVLGHTLSPQGRLPTKIR
DAIAYLPQNFSFDRRIPMTVEEVVGLGWHTLGLQWPWTGHRARQIAVRQALGQVEALHLKRKRISDLSGGETKRVLLAYC
LVRPRRLLILDEAPAGLDLRAEAEFYQLLNQLKQQHGWAILQVSHDLNMVQRQCDHVLCINRTLLCEGVPEVALSRESLS
TVYGPEFARYHHSCSL

Sequences:

>Translated_256_residues
MPEAILRVSGLTVVRDKHVAVEQVSFAVQPGTNVAIVGPNGAGKSSLIQAVLGVLPRQVGQVEVLGHTLSPQGRLPTKIR
DAIAYLPQNFSFDRRIPMTVEEVVGLGWHTLGLQWPWTGHRARQIAVRQALGQVEALHLKRKRISDLSGGETKRVLLAYC
LVRPRRLLILDEAPAGLDLRAEAEFYQLLNQLKQQHGWAILQVSHDLNMVQRQCDHVLCINRTLLCEGVPEVALSRESLS
TVYGPEFARYHHSCSL
>Mature_255_residues
PEAILRVSGLTVVRDKHVAVEQVSFAVQPGTNVAIVGPNGAGKSSLIQAVLGVLPRQVGQVEVLGHTLSPQGRLPTKIRD
AIAYLPQNFSFDRRIPMTVEEVVGLGWHTLGLQWPWTGHRARQIAVRQALGQVEALHLKRKRISDLSGGETKRVLLAYCL
VRPRRLLILDEAPAGLDLRAEAEFYQLLNQLKQQHGWAILQVSHDLNMVQRQCDHVLCINRTLLCEGVPEVALSRESLST
VYGPEFARYHHSCSL

Specific function: Part of an ATP-driven transport system TM_0123/TM_0124/TM_0125 for a metal. Probably responsible for energy coupling to the transport system [H]

COG id: COG1121

COG function: function code P; ABC-type Mn/Zn transport systems, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI47078218, Length=224, Percent_Identity=29.0178571428571, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI45446740, Length=224, Percent_Identity=29.0178571428571, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI21536376, Length=224, Percent_Identity=25.8928571428571, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1788165, Length=240, Percent_Identity=35, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI1790739, Length=248, Percent_Identity=31.0483870967742, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1790544, Length=229, Percent_Identity=29.6943231441048, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1786803, Length=250, Percent_Identity=27.2, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786345, Length=227, Percent_Identity=28.1938325991189, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789991, Length=257, Percent_Identity=32.6848249027237, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1789593, Length=234, Percent_Identity=28.6324786324786, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1789891, Length=220, Percent_Identity=32.2727272727273, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1788506, Length=232, Percent_Identity=30.6034482758621, Blast_Score=80, Evalue=9e-17,
Organism=Escherichia coli, GI1789864, Length=244, Percent_Identity=27.8688524590164, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790525, Length=252, Percent_Identity=27.7777777777778, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790190, Length=210, Percent_Identity=30.4761904761905, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1786253, Length=196, Percent_Identity=32.1428571428571, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787712, Length=203, Percent_Identity=28.0788177339901, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786319, Length=218, Percent_Identity=27.5229357798165, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87081834, Length=195, Percent_Identity=32.3076923076923, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI48994943, Length=230, Percent_Identity=26.5217391304348, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1787500, Length=204, Percent_Identity=27.4509803921569, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87081709, Length=208, Percent_Identity=25.9615384615385, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87081791, Length=245, Percent_Identity=27.7551020408163, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87081782, Length=233, Percent_Identity=27.8969957081545, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI145693107, Length=205, Percent_Identity=32.6829268292683, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786398, Length=210, Percent_Identity=30, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788761, Length=202, Percent_Identity=26.7326732673267, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787548, Length=237, Percent_Identity=27.0042194092827, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1788225, Length=211, Percent_Identity=24.6445497630332, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788002, Length=235, Percent_Identity=31.063829787234, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789032, Length=237, Percent_Identity=27.8481012658228, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786975, Length=245, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1786563, Length=204, Percent_Identity=25.4901960784314, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789890, Length=243, Percent_Identity=26.7489711934156, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786703, Length=199, Percent_Identity=28.643216080402, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789672, Length=215, Percent_Identity=24.1860465116279, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1787792, Length=240, Percent_Identity=24.5833333333333, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788540, Length=197, Percent_Identity=28.9340101522843, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI48994997, Length=232, Percent_Identity=26.2931034482759, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1787370, Length=219, Percent_Identity=22.3744292237443, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1787164, Length=206, Percent_Identity=30.5825242718447, Blast_Score=61, Evalue=8e-11,
Organism=Escherichia coli, GI1788897, Length=206, Percent_Identity=23.3009708737864, Blast_Score=60, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17541710, Length=190, Percent_Identity=26.8421052631579, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71983523, Length=244, Percent_Identity=23.7704918032787, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71983516, Length=244, Percent_Identity=23.7704918032787, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71983510, Length=244, Percent_Identity=23.7704918032787, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17510237, Length=245, Percent_Identity=23.6734693877551, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24666092, Length=211, Percent_Identity=27.0142180094787, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 28429; Mature: 28298

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEAILRVSGLTVVRDKHVAVEQVSFAVQPGTNVAIVGPNGAGKSSLIQAVLGVLPRQVG
CCCHHEEECCEEEEECCCHHHHHHEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHCC
QVEVLGHTLSPQGRLPTKIRDAIAYLPQNFSFDRRIPMTVEEVVGLGWHTLGLQWPWTGH
CEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCHHCCEECCCCCH
RARQIAVRQALGQVEALHLKRKRISDLSGGETKRVLLAYCLVRPRRLLILDEAPAGLDLR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCC
AEAEFYQLLNQLKQQHGWAILQVSHDLNMVQRQCDHVLCINRTLLCEGVPEVALSRESLS
CHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHCCCEEECCCCHHHCCCHHHHHHHHHHH
TVYGPEFARYHHSCSL
HHCCCHHHHHHHCCCC
>Mature Secondary Structure 
PEAILRVSGLTVVRDKHVAVEQVSFAVQPGTNVAIVGPNGAGKSSLIQAVLGVLPRQVG
CCHHEEECCEEEEECCCHHHHHHEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHCC
QVEVLGHTLSPQGRLPTKIRDAIAYLPQNFSFDRRIPMTVEEVVGLGWHTLGLQWPWTGH
CEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCHHCCEECCCCCH
RARQIAVRQALGQVEALHLKRKRISDLSGGETKRVLLAYCLVRPRRLLILDEAPAGLDLR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCC
AEAEFYQLLNQLKQQHGWAILQVSHDLNMVQRQCDHVLCINRTLLCEGVPEVALSRESLS
CHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHCCCEEECCCCHHHCCCHHHHHHHHHHH
TVYGPEFARYHHSCSL
HHCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]