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The map label for this gene is cadC [H]

Identifier: 158336158

GI number: 158336158

Start: 3046934

End: 3047299

Strand: Reverse

Name: cadC [H]

Synonym: AM1_3020

Alternate gene names: 158336158

Gene position: 3047299-3046934 (Counterclockwise)

Preceding gene: 158336163

Following gene: 158336157

Centisome position: 46.85

GC content: 48.63

Gene sequence:

>366_bases
GTGACCCAGACTAAGCCCACAGATATTTGCCAAGTCCGTTGTTTTAACCAAGACTTGGTCACCCAAGCGAATGAAGCACT
GCCGGGAGAAGATCTGCTGGTGGAGGCTCAAGTGCTGTTCAGTGCGTTAGCGGATCGGTCCCGATTAAAGATTTTGTATG
CCCTGAGTGAAGGAACTGAACTCTGTGTTTGTGATGTTGCGTCTTTGCTGGGGATGAAGATCGCAACGGCATCCCACCAC
TTACGAAAGCTACGGGATCTCCAAATTCTGAAGTATCGCAATGATGGCAAATTAGCGTACTACTCTCTCAAGGATCAGCG
CGTCGCTGAGATTCTCCACCATACACTGAACCAACTGGTTGAATAA

Upstream 100 bases:

>100_bases
TATCTGCGATTTCATCCTTTTAGATAGCAGCATTGGGTACAACGCCTCAACAGTTGGTCGTTAAAATCTAAGAGCAGGTA
AGGTGTAACCCTTCAAATTT

Downstream 100 bases:

>100_bases
GTCATTCTAATGTTGGCTTGAATGTTTGAATTGGGTGCGGTAACGTTCTAATACTGCTTTGAATGTTTGAATGTGGAGAG
CCACTATGGGTGATCATTGC

Product: cadmium efflux system accessory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 121; Mature: 120

Protein sequence:

>121_residues
MTQTKPTDICQVRCFNQDLVTQANEALPGEDLLVEAQVLFSALADRSRLKILYALSEGTELCVCDVASLLGMKIATASHH
LRKLRDLQILKYRNDGKLAYYSLKDQRVAEILHHTLNQLVE

Sequences:

>Translated_121_residues
MTQTKPTDICQVRCFNQDLVTQANEALPGEDLLVEAQVLFSALADRSRLKILYALSEGTELCVCDVASLLGMKIATASHH
LRKLRDLQILKYRNDGKLAYYSLKDQRVAEILHHTLNQLVE
>Mature_120_residues
TQTKPTDICQVRCFNQDLVTQANEALPGEDLLVEAQVLFSALADRSRLKILYALSEGTELCVCDVASLLGMKIATASHHL
RKLRDLQILKYRNDGKLAYYSLKDQRVAEILHHTLNQLVE

Specific function: Metal-binding repressor for the cad operon. Involved in resistance to heavy metals, such as cadmium, bismuth, zinc or lead. Metal binding causes the repressor to dissociate from the DNA [H]

COG id: NA

COG function: NA

Gene ontology:
GO:0003677: Cadmium efflux system accessory protein
GO:0003700: Cadmium efflux system accessory protein
GO:0005622: Cadmium efflux system accessory protein
GO:0006351: Cadmium efflux system accessory protein
GO:0006355: Cadmium efflux system accessory protein

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 13655; Mature: 13524

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTKPTDICQVRCFNQDLVTQANEALPGEDLLVEAQVLFSALADRSRLKILYALSEGTE
CCCCCCCCEEEEEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCE
LCVCDVASLLGMKIATASHHLRKLRDLQILKYRNDGKLAYYSLKDQRVAEILHHTLNQLV
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCHHHHHHHHHHHHHHHC
E
C
>Mature Secondary Structure 
TQTKPTDICQVRCFNQDLVTQANEALPGEDLLVEAQVLFSALADRSRLKILYALSEGTE
CCCCCCCEEEEEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCE
LCVCDVASLLGMKIATASHHLRKLRDLQILKYRNDGKLAYYSLKDQRVAEILHHTLNQLV
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCHHHHHHHHHHHHHHHC
E
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1321115 [H]