Click here to switch to the map view.

The map label for this gene is pksA [H]

Identifier: 158336156

GI number: 158336156

Start: 3045534

End: 3046121

Strand: Direct

Name: pksA [H]

Synonym: AM1_3018

Alternate gene names: 158336156

Gene position: 3045534-3046121 (Clockwise)

Preceding gene: 158336152

Following gene: 158336159

Centisome position: 46.83

GC content: 51.19

Gene sequence:

>588_bases
ATGTCTCAGCAAGACCGGCGTCTTGAAGTCTCTGAAGCTGCCTGGCGTGTCATCGTCAGGGAGGGGTTAGACCGTGCCAG
TATGCGTGCGATCGCACAGGAAATGAATTGCACGACAGGGGTCGTCACCCATTATTTCCGAAATAAGCAGGAGCTAATTC
TGTTTGCCTTGCATCAGGTCACAGAACGCTTGAAAGTGAGGATGCAGGTGGCAATTGAGAATGTCGCGGGAATTGATCGA
TTGGCAACAATGCTATTGTCCTTTCTGCCACTAGACCAAGAACGGCAAGAAATCCTCCGGGTATGGGTTGCTTTTTTAGG
CTACGCCGTTGGCCGTGATGGTTTGATGGAAGAGCATCGACAGAGTGCCGCAGAACTGCGGGCAGTCATCATTCAGGAGT
TGCAAGCTCTCCAATCCAAGGGGCTTATTCAGGCAGATCTCGTGCCTCAAGTGGAGGCCAATGCCCTACTTGCCCTTGTC
AATGGCATTGGTATAGATACCTTGATTCAGGCTGACCATCTAGGTCCTGGTCAGCAAGAGGCAATCATTCATCGGTACAT
CGCAGGTATGGTGACAGGTCAGTGTTGA

Upstream 100 bases:

>100_bases
TCTTTCATATTCGTAGCATCATAACAGTTGTTATGTAATCAACATAATGACTGTTATGATATTTGTCAATCGAGTTTGTA
CTTCGTTGTAGTTAACGTTT

Downstream 100 bases:

>100_bases
AGATGATTTAAATTGAACGGACAGAGATCCCTCAATTGATCTTCGATATCTCAGCAAGCCAAGCGAATGAAATCCTGAAA
GCATAGATACACCGCCTATA

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MSQQDRRLEVSEAAWRVIVREGLDRASMRAIAQEMNCTTGVVTHYFRNKQELILFALHQVTERLKVRMQVAIENVAGIDR
LATMLLSFLPLDQERQEILRVWVAFLGYAVGRDGLMEEHRQSAAELRAVIIQELQALQSKGLIQADLVPQVEANALLALV
NGIGIDTLIQADHLGPGQQEAIIHRYIAGMVTGQC

Sequences:

>Translated_195_residues
MSQQDRRLEVSEAAWRVIVREGLDRASMRAIAQEMNCTTGVVTHYFRNKQELILFALHQVTERLKVRMQVAIENVAGIDR
LATMLLSFLPLDQERQEILRVWVAFLGYAVGRDGLMEEHRQSAAELRAVIIQELQALQSKGLIQADLVPQVEANALLALV
NGIGIDTLIQADHLGPGQQEAIIHRYIAGMVTGQC
>Mature_194_residues
SQQDRRLEVSEAAWRVIVREGLDRASMRAIAQEMNCTTGVVTHYFRNKQELILFALHQVTERLKVRMQVAIENVAGIDRL
ATMLLSFLPLDQERQEILRVWVAFLGYAVGRDGLMEEHRQSAAELRAVIIQELQALQSKGLIQADLVPQVEANALLALVN
GIGIDTLIQADHLGPGQQEAIIHRYIAGMVTGQC

Specific function: Transcriptional regulation of the polyketide synthase operon [H]

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 21823; Mature: 21692

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQQDRRLEVSEAAWRVIVREGLDRASMRAIAQEMNCTTGVVTHYFRNKQELILFALHQV
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHH
TERLKVRMQVAIENVAGIDRLATMLLSFLPLDQERQEILRVWVAFLGYAVGRDGLMEEHR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
QSAAELRAVIIQELQALQSKGLIQADLVPQVEANALLALVNGIGIDTLIQADHLGPGQQE
HHHHHHHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCHHH
AIIHRYIAGMVTGQC
HHHHHHHHHHHCCCC
>Mature Secondary Structure 
SQQDRRLEVSEAAWRVIVREGLDRASMRAIAQEMNCTTGVVTHYFRNKQELILFALHQV
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHH
TERLKVRMQVAIENVAGIDRLATMLLSFLPLDQERQEILRVWVAFLGYAVGRDGLMEEHR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
QSAAELRAVIIQELQALQSKGLIQADLVPQVEANALLALVNGIGIDTLIQADHLGPGQQE
HHHHHHHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCHHH
AIIHRYIAGMVTGQC
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]