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The map label for this gene is sodA2 [H]

Identifier: 158336100

GI number: 158336100

Start: 2992273

End: 2992953

Strand: Direct

Name: sodA2 [H]

Synonym: AM1_2962

Alternate gene names: 158336100

Gene position: 2992273-2992953 (Clockwise)

Preceding gene: 158336099

Following gene: 158336102

Centisome position: 46.01

GC content: 50.07

Gene sequence:

>681_bases
ATGCAGCCTGCGGCATGGTCTCAAGCATTGACGGACTCTCCAGATAGCAATCTGATTGCCCAGGCTGATGAAGGCTTTAC
AGTGCCTCCCCTTCCCTATAGCTACTTTGCCCTGGAAAAATACATCGATACCAAAACCATGAAAATCCATCATGATAAGC
ATCATGCTGGGTATGTCAATAATTTGAATGCTGCCATCGCCAAGCACCCCAACTTAGCGGGTAAATCCGTTGAAGATCTC
CTAACAGATCTGAATGCCGTGCCCGAGGATATTCGCACCGCAGTTCGCAACAATGGGGGCGGCCATGCGAATCACACCTT
ATTTTGGGACAGCATGACCCCGAATGCCGAAGGCAAACCGAAGGGCAAACTCGCCGACGCGATTGAGGAAAGCTTTGGCA
GTTTTGTGGCCTTCCAATCCGAATTCAAAAAAGCGGGTTTAACGCGATTCGGGAGCGGTTGGGCTTGGTTAGTGCTGACG
AAAGATGGCAAGCTAGCCGTTACCAGTACCCCCAACCAAGATAGCCCTCTTCTAGACGGCAATATTCCGCTACTGGGCAA
TGACGTCTGGGAACATGCCTACTATCTGAAATATCAAAATCGCCGCGGTGACTATCTAGACGCTTGGTGGAATGTCGTGA
ATTGGGCAGAAGTGGAATCCCGCTATGAGAAAGCAACCTAA

Upstream 100 bases:

>100_bases
CAAGAACTGAGGACTTTTTCGGGTGTAAGTTATGCGGTTTCGATTCTCCAATACGCTTCTAGTGATCGTTATGTTCGTCA
GCGTGGTGACCTGGAATGCC

Downstream 100 bases:

>100_bases
CCGGTCGTTGGGCGATTTAATTCATTGAGGTCCGTCGAAAAATAAATATGTCAAATTTTGCAGTCTTGCTGATGGCATTC
GAGAAAAAAGTCGACCGGAC

Product: superoxide dismutase Mn/Fe domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MQPAAWSQALTDSPDSNLIAQADEGFTVPPLPYSYFALEKYIDTKTMKIHHDKHHAGYVNNLNAAIAKHPNLAGKSVEDL
LTDLNAVPEDIRTAVRNNGGGHANHTLFWDSMTPNAEGKPKGKLADAIEESFGSFVAFQSEFKKAGLTRFGSGWAWLVLT
KDGKLAVTSTPNQDSPLLDGNIPLLGNDVWEHAYYLKYQNRRGDYLDAWWNVVNWAEVESRYEKAT

Sequences:

>Translated_226_residues
MQPAAWSQALTDSPDSNLIAQADEGFTVPPLPYSYFALEKYIDTKTMKIHHDKHHAGYVNNLNAAIAKHPNLAGKSVEDL
LTDLNAVPEDIRTAVRNNGGGHANHTLFWDSMTPNAEGKPKGKLADAIEESFGSFVAFQSEFKKAGLTRFGSGWAWLVLT
KDGKLAVTSTPNQDSPLLDGNIPLLGNDVWEHAYYLKYQNRRGDYLDAWWNVVNWAEVESRYEKAT
>Mature_226_residues
MQPAAWSQALTDSPDSNLIAQADEGFTVPPLPYSYFALEKYIDTKTMKIHHDKHHAGYVNNLNAAIAKHPNLAGKSVEDL
LTDLNAVPEDIRTAVRNNGGGHANHTLFWDSMTPNAEGKPKGKLADAIEESFGSFVAFQSEFKKAGLTRFGSGWAWLVLT
KDGKLAVTSTPNQDSPLLDGNIPLLGNDVWEHAYYLKYQNRRGDYLDAWWNVVNWAEVESRYEKAT

Specific function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems [H]

COG id: COG0605

COG function: function code P; Superoxide dismutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron/manganese superoxide dismutase family [H]

Homologues:

Organism=Homo sapiens, GI67782307, Length=199, Percent_Identity=48.2412060301507, Blast_Score=186, Evalue=2e-47,
Organism=Homo sapiens, GI67782305, Length=199, Percent_Identity=48.2412060301507, Blast_Score=186, Evalue=2e-47,
Organism=Homo sapiens, GI67782309, Length=199, Percent_Identity=40.2010050251256, Blast_Score=136, Evalue=2e-32,
Organism=Escherichia coli, GI1790342, Length=203, Percent_Identity=54.679802955665, Blast_Score=223, Evalue=1e-59,
Organism=Escherichia coli, GI1787946, Length=193, Percent_Identity=45.5958549222798, Blast_Score=171, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17506561, Length=211, Percent_Identity=40.2843601895735, Blast_Score=155, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17569479, Length=201, Percent_Identity=39.3034825870647, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6321796, Length=213, Percent_Identity=41.7840375586854, Blast_Score=144, Evalue=1e-35,
Organism=Drosophila melanogaster, GI17136812, Length=202, Percent_Identity=44.5544554455446, Blast_Score=164, Evalue=5e-41,

Paralogues:

None

Copy number: 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001189
- InterPro:   IPR019833
- InterPro:   IPR019832
- InterPro:   IPR019831 [H]

Pfam domain/function: PF02777 Sod_Fe_C; PF00081 Sod_Fe_N [H]

EC number: =1.15.1.1 [H]

Molecular weight: Translated: 25149; Mature: 25149

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS00088 SOD_MN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPAAWSQALTDSPDSNLIAQADEGFTVPPLPYSYFALEKYIDTKTMKIHHDKHHAGYVN
CCCCHHHHHHCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCC
NLNAAIAKHPNLAGKSVEDLLTDLNAVPEDIRTAVRNNGGGHANHTLFWDSMTPNAEGKP
CCCHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCC
KGKLADAIEESFGSFVAFQSEFKKAGLTRFGSGWAWLVLTKDGKLAVTSTPNQDSPLLDG
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEECCCCCCCCEECC
NIPLLGNDVWEHAYYLKYQNRRGDYLDAWWNVVNWAEVESRYEKAT
CCCCCCCHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQPAAWSQALTDSPDSNLIAQADEGFTVPPLPYSYFALEKYIDTKTMKIHHDKHHAGYVN
CCCCHHHHHHCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCC
NLNAAIAKHPNLAGKSVEDLLTDLNAVPEDIRTAVRNNGGGHANHTLFWDSMTPNAEGKP
CCCHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCC
KGKLADAIEESFGSFVAFQSEFKKAGLTRFGSGWAWLVLTKDGKLAVTSTPNQDSPLLDG
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEECCCCCCCCEECC
NIPLLGNDVWEHAYYLKYQNRRGDYLDAWWNVVNWAEVESRYEKAT
CCCCCCCHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7860607 [H]