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The map label for this gene is gloA [C]

Identifier: 158336052

GI number: 158336052

Start: 2946529

End: 2946912

Strand: Direct

Name: gloA [C]

Synonym: AM1_2911

Alternate gene names: 158336052

Gene position: 2946529-2946912 (Clockwise)

Preceding gene: 158336051

Following gene: 158336053

Centisome position: 45.31

GC content: 49.48

Gene sequence:

>384_bases
ATGACAGTAACTCAGTTTTTACATGCAGCCTTGCTTGTACAGGATTTAGAGCGCTCTCGGCAGTTTTATGGTGAGTTGCT
GGGCCTAACGGAATGTCCTCGTCCCTTTGATTTCTCTGGGGCTTGGTATCAAATCGGTCCTCAACAGCTCCATATCATGG
TGTCTCCAGAGTATTCTGCCCAACAAGCCGATCAAGAACGTTGGGGGCGCAATCGCCATGTGGCTTTGGCGGTTTCCAAT
CTAGAGGACTGTCAAACCCAGCTCAAAGCAGCTGGAGTGACCTATCAGTTAAGCCATTCGGGCCGAGCTGCATTATTTGT
GCACGATCCAGATGGCAACATTATTGAGCTAAGCCAAGTCGATGCCCCATCTAGCCAGAATTGA

Upstream 100 bases:

>100_bases
CTCCCGTAGATGTGATGATCGATATTACGGGTGCCTTGATTGCAGTGGGCTTGATCAGTATTTGGAAAACCCAATTTCAA
CCTGAGACGAAACAAGATCG

Downstream 100 bases:

>100_bases
TCTGTATCCCTTTAAGTCTTTGGATGGCGTTACGGTCCGATCCGCCAATATTTTGGCGAGTGGAGCCCTAGAACATGATC
GGGAATATGCTTGCTTTGAT

Product: glyoxalase/bleomycin resistance protein/dioxygenase

Products: (R)-S-Lactoylglutathione [C]

Alternate protein names: Glyoxalase Family Protein; Glyoxalase Family Protein Superfamily

Number of amino acids: Translated: 127; Mature: 126

Protein sequence:

>127_residues
MTVTQFLHAALLVQDLERSRQFYGELLGLTECPRPFDFSGAWYQIGPQQLHIMVSPEYSAQQADQERWGRNRHVALAVSN
LEDCQTQLKAAGVTYQLSHSGRAALFVHDPDGNIIELSQVDAPSSQN

Sequences:

>Translated_127_residues
MTVTQFLHAALLVQDLERSRQFYGELLGLTECPRPFDFSGAWYQIGPQQLHIMVSPEYSAQQADQERWGRNRHVALAVSN
LEDCQTQLKAAGVTYQLSHSGRAALFVHDPDGNIIELSQVDAPSSQN
>Mature_126_residues
TVTQFLHAALLVQDLERSRQFYGELLGLTECPRPFDFSGAWYQIGPQQLHIMVSPEYSAQQADQERWGRNRHVALAVSNL
EDCQTQLKAAGVTYQLSHSGRAALFVHDPDGNIIELSQVDAPSSQN

Specific function: Catalyzes The Conversion Of Hemimercaptal, Formed From Methylglyoxal And Glutathione, To S-Lactoylglutathione. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.4.1.5 [C]

Molecular weight: Translated: 14213; Mature: 14082

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVTQFLHAALLVQDLERSRQFYGELLGLTECPRPFDFSGAWYQIGPQQLHIMVSPEYSA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCEEEEEEECCCCCH
QQADQERWGRNRHVALAVSNLEDCQTQLKAAGVTYQLSHSGRAALFVHDPDGNIIELSQV
HHHHHHHCCCCCEEEEEECCHHHHHHHHHHCCCEEEECCCCCEEEEEECCCCCEEEEEEC
DAPSSQN
CCCCCCC
>Mature Secondary Structure 
TVTQFLHAALLVQDLERSRQFYGELLGLTECPRPFDFSGAWYQIGPQQLHIMVSPEYSA
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCEEEEEEECCCCCH
QQADQERWGRNRHVALAVSNLEDCQTQLKAAGVTYQLSHSGRAALFVHDPDGNIIELSQV
HHHHHHHCCCCCEEEEEECCHHHHHHHHHHCCCEEEECCCCCEEEEEECCCCCEEEEEEC
DAPSSQN
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): 20280 [C]

Specific activity: NA

Km value (mM): 0.0272 {methylglyoxal/glutathione} [C]

Substrates: Reduced glutathione; Methylglyoxal [C]

Specific reaction: Reduced glutathione + Methylglyoxal --> (R)-S-Lactoylglutathione [C]

General reaction: addition of RSH [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA