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The map label for this gene is spkF [H]

Identifier: 158336027

GI number: 158336027

Start: 2925365

End: 2926969

Strand: Direct

Name: spkF [H]

Synonym: AM1_2886

Alternate gene names: 158336027

Gene position: 2925365-2926969 (Clockwise)

Preceding gene: 158336026

Following gene: 158336029

Centisome position: 44.98

GC content: 49.84

Gene sequence:

>1605_bases
ATGACTCTCTGTATCGCCCCTCAATGTTCCAAGCCAGAAAATCCTGACAACAGTGTATTTTGCCAAACCTGTGGATCAGA
ATTGCTCTTAGAAGGTCGATATCGCGTCACCAAACTGATCGGCCAAGGTGGATTTGGCAAAACCTACGAAGTGCGTGAAG
TCGTCAGAGCTACAGGCACCAGCAATAGCGGCATTCCTAAAGTGCTCAAAGTCTTAACCGATCAACAGCCCAAAGCCGTT
GAACTCTTTACGCGCGAAGCACAAGTTCTCAGCCAGCTCCGCCATCCTGGGATTCCCCAGGTCGATACAGACGGTCACTT
TATCTTCTGGCCTCGGGACAGCCAAACTGCCCTGCACTGCCTCATCATGGAAAAAATCGAGGGGCTAGATCTGTGCGGTT
ATATGAAGCAGCGCCAGTTTCGGCCCATTAGCGAACAGCTGGCCTTGGAATGGTTGATGCAAATCATGACCATTCTCAAT
GAAGTCCATGGCCAGCTGTTTTTCCATCGTGACATCAAACCCTCCAACATCATGCTGCGTCCAGATGGTCAATTGGTGCT
GATTGACTTTGGTGCCGTCAGAGCGGTCACCCAAACTTACATGGCCAAGCAAGGGGCTCAAGGGATAACCGGCATTCATT
CTATGGGGTTTACGCCTCCTGAGCAGATGAATGGACAGGCTGTGATGCAGTCTGACTTCTACGCCCTGGGCCGAACATGG
GTCTATCTACTAACCGGTAAAGAGCCCACGGATAGCAGCATCTATGATCCCTATAACGATCAATGCCAATGGCGAGAATC
AGCGACCCATATTTCACCCCCCTTAGCCAATTTAGTGGATGACTTAATGGCCCGATTACCCAAAGATCGGCCTGCCAACA
CCCAAATTATTCTGCAGCGCCTACGAACACTAGATCGAGAGTTCGAGCAATCCCGCCAGCAAACTGAAGTCAGCCAAGGG
TCTAATCCACCCCCTTTTCCCCAGTCATCAGCCACACCCAGCTCTGCAGCTCAGCCGCCTCCTGTCCCTCCATCAAACGT
GCCTCCTACAGATATTCAGGCACCGCCTGAAGCATTACCAATCTATACGCCGCCTTCAACTGCGCCTTTCTCCACTTCAC
AACCGTCTGCAGGTGTACCACCTACGGATATTCAGGCACCTGGGTATTCCACACCATCCCATCCCCCTAACCAACCCAGT
CAACCACAACAAAGTCCACCGCCGTTAACATCTTCAGCCCATGAACTAGAGGAGGCCAACAGACAGATCAAAACCGCCTG
GATTGCAGGTACTGTCACTACGGTTATCACGCTGCTGGCCATGCTGGTGCTATCAGGGTCAGAAGAAGGAGGCTTACTAT
GGATCGATGTCTTGCTAACCGCAAGTTTTACGTTTGGTATTTATAAAAAAATCCGCGCCTGCGCTGTACTGATGTTGATC
TACTTTATTTTGAGTAAATTGCTACAAATCATTGCCGCTCTTGAAGCCGATGCAGGGATTAATCCGATTGCCATCGGATT
TGGAGGGCTCTTTCTTTATTTCTATGCTCAAGGTGTCAAAGGAACTTATACATATCATCGATTGTCAAATCAACAGCAGC
CTTAA

Upstream 100 bases:

>100_bases
GTCTCGATAACTGAAATTTGCAAGATGACGCTCCCCTCAGCTTTTTTGTCAGACTATGGGAGAGTAATATTCTCTCAGCA
GCCAAGATCACATCCTTGCT

Downstream 100 bases:

>100_bases
GTGCATCAGGATAAAGACGATCTATTTCTCCGGGTGAGTGGCAATCCAGTTGCTCACTATCTGGTTAACTTGATGCGGCT
CTTCATCCTGAGGACAGTGC

Product: serine/threonine protein kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 534; Mature: 533

Protein sequence:

>534_residues
MTLCIAPQCSKPENPDNSVFCQTCGSELLLEGRYRVTKLIGQGGFGKTYEVREVVRATGTSNSGIPKVLKVLTDQQPKAV
ELFTREAQVLSQLRHPGIPQVDTDGHFIFWPRDSQTALHCLIMEKIEGLDLCGYMKQRQFRPISEQLALEWLMQIMTILN
EVHGQLFFHRDIKPSNIMLRPDGQLVLIDFGAVRAVTQTYMAKQGAQGITGIHSMGFTPPEQMNGQAVMQSDFYALGRTW
VYLLTGKEPTDSSIYDPYNDQCQWRESATHISPPLANLVDDLMARLPKDRPANTQIILQRLRTLDREFEQSRQQTEVSQG
SNPPPFPQSSATPSSAAQPPPVPPSNVPPTDIQAPPEALPIYTPPSTAPFSTSQPSAGVPPTDIQAPGYSTPSHPPNQPS
QPQQSPPPLTSSAHELEEANRQIKTAWIAGTVTTVITLLAMLVLSGSEEGGLLWIDVLLTASFTFGIYKKIRACAVLMLI
YFILSKLLQIIAALEADAGINPIAIGFGGLFLYFYAQGVKGTYTYHRLSNQQQP

Sequences:

>Translated_534_residues
MTLCIAPQCSKPENPDNSVFCQTCGSELLLEGRYRVTKLIGQGGFGKTYEVREVVRATGTSNSGIPKVLKVLTDQQPKAV
ELFTREAQVLSQLRHPGIPQVDTDGHFIFWPRDSQTALHCLIMEKIEGLDLCGYMKQRQFRPISEQLALEWLMQIMTILN
EVHGQLFFHRDIKPSNIMLRPDGQLVLIDFGAVRAVTQTYMAKQGAQGITGIHSMGFTPPEQMNGQAVMQSDFYALGRTW
VYLLTGKEPTDSSIYDPYNDQCQWRESATHISPPLANLVDDLMARLPKDRPANTQIILQRLRTLDREFEQSRQQTEVSQG
SNPPPFPQSSATPSSAAQPPPVPPSNVPPTDIQAPPEALPIYTPPSTAPFSTSQPSAGVPPTDIQAPGYSTPSHPPNQPS
QPQQSPPPLTSSAHELEEANRQIKTAWIAGTVTTVITLLAMLVLSGSEEGGLLWIDVLLTASFTFGIYKKIRACAVLMLI
YFILSKLLQIIAALEADAGINPIAIGFGGLFLYFYAQGVKGTYTYHRLSNQQQP
>Mature_533_residues
TLCIAPQCSKPENPDNSVFCQTCGSELLLEGRYRVTKLIGQGGFGKTYEVREVVRATGTSNSGIPKVLKVLTDQQPKAVE
LFTREAQVLSQLRHPGIPQVDTDGHFIFWPRDSQTALHCLIMEKIEGLDLCGYMKQRQFRPISEQLALEWLMQIMTILNE
VHGQLFFHRDIKPSNIMLRPDGQLVLIDFGAVRAVTQTYMAKQGAQGITGIHSMGFTPPEQMNGQAVMQSDFYALGRTWV
YLLTGKEPTDSSIYDPYNDQCQWRESATHISPPLANLVDDLMARLPKDRPANTQIILQRLRTLDREFEQSRQQTEVSQGS
NPPPFPQSSATPSSAAQPPPVPPSNVPPTDIQAPPEALPIYTPPSTAPFSTSQPSAGVPPTDIQAPGYSTPSHPPNQPSQ
PQQSPPPLTSSAHELEEANRQIKTAWIAGTVTTVITLLAMLVLSGSEEGGLLWIDVLLTASFTFGIYKKIRACAVLMLIY
FILSKLLQIIAALEADAGINPIAIGFGGLFLYFYAQGVKGTYTYHRLSNQQQP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI225735561, Length=272, Percent_Identity=26.1029411764706, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI41872673, Length=278, Percent_Identity=26.978417266187, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI83627721, Length=275, Percent_Identity=26.5454545454545, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI32528295, Length=313, Percent_Identity=26.8370607028754, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI32528297, Length=313, Percent_Identity=26.8370607028754, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI42794767, Length=217, Percent_Identity=27.6497695852535, Blast_Score=76, Evalue=9e-14,
Organism=Homo sapiens, GI42794765, Length=217, Percent_Identity=27.6497695852535, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI13569922, Length=226, Percent_Identity=26.5486725663717, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI85838511, Length=217, Percent_Identity=26.7281105990783, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI55953117, Length=267, Percent_Identity=25.8426966292135, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI4506735, Length=274, Percent_Identity=25.1824817518248, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI55743138, Length=274, Percent_Identity=25.1824817518248, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI148839316, Length=272, Percent_Identity=24.6323529411765, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI4557511, Length=229, Percent_Identity=26.6375545851528, Blast_Score=66, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI193210728, Length=259, Percent_Identity=25.8687258687259, Blast_Score=79, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17570595, Length=219, Percent_Identity=30.5936073059361, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193203107, Length=226, Percent_Identity=27.4336283185841, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71989893, Length=226, Percent_Identity=27.4336283185841, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71989905, Length=226, Percent_Identity=27.4336283185841, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71989911, Length=226, Percent_Identity=27.8761061946903, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71989900, Length=226, Percent_Identity=27.4336283185841, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17555466, Length=309, Percent_Identity=23.3009708737864, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6319502, Length=287, Percent_Identity=22.9965156794425, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI161077455, Length=281, Percent_Identity=24.1992882562278, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI161077453, Length=281, Percent_Identity=24.1992882562278, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17136516, Length=275, Percent_Identity=24.7272727272727, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI21358073, Length=263, Percent_Identity=23.574144486692, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017441
- InterPro:   IPR017442 [H]

Pfam domain/function: PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 58839; Mature: 58708

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00108 PROTEIN_KINASE_ST ; PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLCIAPQCSKPENPDNSVFCQTCGSELLLEGRYRVTKLIGQGGFGKTYEVREVVRATGT
CEEEECCCCCCCCCCCCCEEHHHCCCHHEECCHHHHHHHHCCCCCCCHHHHHHHHHHCCC
SNSGIPKVLKVLTDQQPKAVELFTREAQVLSQLRHPGIPQVDTDGHFIFWPRDSQTALHC
CCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHH
LIMEKIEGLDLCGYMKQRQFRPISEQLALEWLMQIMTILNEVHGQLFFHRDIKPSNIMLR
HHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCEEEC
PDGQLVLIDFGAVRAVTQTYMAKQGAQGITGIHSMGFTPPEQMNGQAVMQSDFYALGRTW
CCCCEEEEECHHHHHHHHHHHHHCCCCCCCHHHHCCCCCHHHCCCCEEHHHHHHHHCCEE
VYLLTGKEPTDSSIYDPYNDQCQWRESATHISPPLANLVDDLMARLPKDRPANTQIILQR
EEEEECCCCCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHH
LRTLDREFEQSRQQTEVSQGSNPPPFPQSSATPSSAAQPPPVPPSNVPPTDIQAPPEALP
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCE
IYTPPSTAPFSTSQPSAGVPPTDIQAPGYSTPSHPPNQPSQPQQSPPPLTSSAHELEEAN
EECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
RQIKTAWIAGTVTTVITLLAMLVLSGSEEGGLLWIDVLLTASFTFGIYKKIRACAVLMLI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
YFILSKLLQIIAALEADAGINPIAIGFGGLFLYFYAQGVKGTYTYHRLSNQQQP
HHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHCCCCCCCHHHHCCCCCCC
>Mature Secondary Structure 
TLCIAPQCSKPENPDNSVFCQTCGSELLLEGRYRVTKLIGQGGFGKTYEVREVVRATGT
EEEECCCCCCCCCCCCCEEHHHCCCHHEECCHHHHHHHHCCCCCCCHHHHHHHHHHCCC
SNSGIPKVLKVLTDQQPKAVELFTREAQVLSQLRHPGIPQVDTDGHFIFWPRDSQTALHC
CCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHH
LIMEKIEGLDLCGYMKQRQFRPISEQLALEWLMQIMTILNEVHGQLFFHRDIKPSNIMLR
HHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCEEEC
PDGQLVLIDFGAVRAVTQTYMAKQGAQGITGIHSMGFTPPEQMNGQAVMQSDFYALGRTW
CCCCEEEEECHHHHHHHHHHHHHCCCCCCCHHHHCCCCCHHHCCCCEEHHHHHHHHCCEE
VYLLTGKEPTDSSIYDPYNDQCQWRESATHISPPLANLVDDLMARLPKDRPANTQIILQR
EEEEECCCCCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHH
LRTLDREFEQSRQQTEVSQGSNPPPFPQSSATPSSAAQPPPVPPSNVPPTDIQAPPEALP
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCE
IYTPPSTAPFSTSQPSAGVPPTDIQAPGYSTPSHPPNQPSQPQQSPPPLTSSAHELEEAN
EECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
RQIKTAWIAGTVTTVITLLAMLVLSGSEEGGLLWIDVLLTASFTFGIYKKIRACAVLMLI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
YFILSKLLQIIAALEADAGINPIAIGFGGLFLYFYAQGVKGTYTYHRLSNQQQP
HHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHCCCCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12168951; 8905231 [H]