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The map label for this gene is 158335987

Identifier: 158335987

GI number: 158335987

Start: 2888633

End: 2889547

Strand: Direct

Name: 158335987

Synonym: AM1_2845

Alternate gene names: NA

Gene position: 2888633-2889547 (Clockwise)

Preceding gene: 158335980

Following gene: 158335988

Centisome position: 44.42

GC content: 47.1

Gene sequence:

>915_bases
GTGGTGTTTTTTCAAAGATTATTTCGTCAACCTCAGCCGCCTAACCATGCCACACCTTCTGAAAGCCTAGAAGCGCGTTT
AGCTGAGTATGATCAGGCGATCGCCCATGGAACAGATAATAACGATGTTTGGTTTGGGCGAGGGTGCGTCCAAGTTGAAC
TGAAGCGGTATCAAGAAGCCATTCGTAGCTTCGATAAGGCTTTGGCCCATCGTCCTAACCATTTAGATAGTTGGCACAAT
CGGTCTTTAGCCTTTTGTCAATTGGGTCTCTATGAAGAAGCGGTGAGTAGCTATGAACAAGCGCTTCATTTTAGTAGCGT
CCCCTCTCAAGATTGGTATTTCTACGGCACCTTACTCGCTCAGCTCGATCGCTATGAAGAAGCCATTGATAGTTACGAGG
AAGCGCTAAAGAAGGATCCTGAACGGGCTTTGATTTGGTACGACCGGGGGATTGCCTTGTCTTGGTTAGGGCAGTTCGAA
GATGCGATCGCAAGTTACGATCAAGCCCTCAATCTAGATGCCACCCTTCACCAAGCCTGGTTCCGACGCGGCTTAGCCTT
TAATCAATGTCACAACTATACCCAAGCTCTAAAATCCTTTGATAAGGCCCTATCAATAGACACCAAAGGTTCTGAAGTAT
GGGCTGCCAAGGGATTAGCACTCCTCCAACTTCAGCAATATAAAGACGCCATTACCGCCCATGATCAAGCGATCAAACTC
AATGCCAAGGATGATCAAGTTTGGTACAACCAAGCCTGCTGCCATGCCCATTGTCAACAGTTAGATCAAGCCATATCCAG
TCTTGAACAAGCCATACACCTCAATCCAGACGCCATCCGTGAATTGGCGAGTACGGATCCCGACTTACAGGTTTTGCATC
AACACCCCACTTTTCAAAAGCTGATTTCGATGTAA

Upstream 100 bases:

>100_bases
TTGCGGTCTCAGCGGTCGGGGGAGCCTGCATTAAGTTGCAGTAGGCCATCGCTTTTTTCAGCAATAGAGTCACGTCCTCT
TTCGAGATGTAAGTTTTACA

Downstream 100 bases:

>100_bases
GTCTCAGTTCTCAGGATTCTTATAAAACGTTCATGGACGATTCAGTCAATCCGATGACTTTACCCAGATAGTCATCATTC
CAGCTTCAGGTACCTCTCTT

Product: TPR domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MVFFQRLFRQPQPPNHATPSESLEARLAEYDQAIAHGTDNNDVWFGRGCVQVELKRYQEAIRSFDKALAHRPNHLDSWHN
RSLAFCQLGLYEEAVSSYEQALHFSSVPSQDWYFYGTLLAQLDRYEEAIDSYEEALKKDPERALIWYDRGIALSWLGQFE
DAIASYDQALNLDATLHQAWFRRGLAFNQCHNYTQALKSFDKALSIDTKGSEVWAAKGLALLQLQQYKDAITAHDQAIKL
NAKDDQVWYNQACCHAHCQQLDQAISSLEQAIHLNPDAIRELASTDPDLQVLHQHPTFQKLISM

Sequences:

>Translated_304_residues
MVFFQRLFRQPQPPNHATPSESLEARLAEYDQAIAHGTDNNDVWFGRGCVQVELKRYQEAIRSFDKALAHRPNHLDSWHN
RSLAFCQLGLYEEAVSSYEQALHFSSVPSQDWYFYGTLLAQLDRYEEAIDSYEEALKKDPERALIWYDRGIALSWLGQFE
DAIASYDQALNLDATLHQAWFRRGLAFNQCHNYTQALKSFDKALSIDTKGSEVWAAKGLALLQLQQYKDAITAHDQAIKL
NAKDDQVWYNQACCHAHCQQLDQAISSLEQAIHLNPDAIRELASTDPDLQVLHQHPTFQKLISM
>Mature_304_residues
MVFFQRLFRQPQPPNHATPSESLEARLAEYDQAIAHGTDNNDVWFGRGCVQVELKRYQEAIRSFDKALAHRPNHLDSWHN
RSLAFCQLGLYEEAVSSYEQALHFSSVPSQDWYFYGTLLAQLDRYEEAIDSYEEALKKDPERALIWYDRGIALSWLGQFE
DAIASYDQALNLDATLHQAWFRRGLAFNQCHNYTQALKSFDKALSIDTKGSEVWAAKGLALLQLQQYKDAITAHDQAIKL
NAKDDQVWYNQACCHAHCQQLDQAISSLEQAIHLNPDAIRELASTDPDLQVLHQHPTFQKLISM

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 8 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307148, Length=238, Percent_Identity=23.9495798319328, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI32307150, Length=238, Percent_Identity=23.9495798319328, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115532690, Length=190, Percent_Identity=25.7894736842105, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI115532692, Length=190, Percent_Identity=25.7894736842105, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319589, Length=299, Percent_Identity=22.4080267558528, Blast_Score=73, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6319387, Length=162, Percent_Identity=29.0123456790123, Blast_Score=69, Evalue=7e-13,
Organism=Drosophila melanogaster, GI17647755, Length=240, Percent_Identity=23.3333333333333, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24585827, Length=240, Percent_Identity=23.3333333333333, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24585829, Length=240, Percent_Identity=23.3333333333333, Blast_Score=74, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 34900; Mature: 34900

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFFQRLFRQPQPPNHATPSESLEARLAEYDQAIAHGTDNNDVWFGRGCVQVELKRYQEA
CCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHH
IRSFDKALAHRPNHLDSWHNRSLAFCQLGLYEEAVSSYEQALHFSSVPSQDWYFYGTLLA
HHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
QLDRYEEAIDSYEEALKKDPERALIWYDRGIALSWLGQFEDAIASYDQALNLDATLHQAW
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
FRRGLAFNQCHNYTQALKSFDKALSIDTKGSEVWAAKGLALLQLQQYKDAITAHDQAIKL
HHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
NAKDDQVWYNQACCHAHCQQLDQAISSLEQAIHLNPDAIRELASTDPDLQVLHQHPTFQK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHCCCHHHH
LISM
HHCC
>Mature Secondary Structure
MVFFQRLFRQPQPPNHATPSESLEARLAEYDQAIAHGTDNNDVWFGRGCVQVELKRYQEA
CCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHH
IRSFDKALAHRPNHLDSWHNRSLAFCQLGLYEEAVSSYEQALHFSSVPSQDWYFYGTLLA
HHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
QLDRYEEAIDSYEEALKKDPERALIWYDRGIALSWLGQFEDAIASYDQALNLDATLHQAW
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
FRRGLAFNQCHNYTQALKSFDKALSIDTKGSEVWAAKGLALLQLQQYKDAITAHDQAIKL
HHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
NAKDDQVWYNQACCHAHCQQLDQAISSLEQAIHLNPDAIRELASTDPDLQVLHQHPTFQK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHCCCHHHH
LISM
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]