Click here to switch to the map view.

The map label for this gene is fabH [H]

Identifier: 158335986

GI number: 158335986

Start: 2886947

End: 2888077

Strand: Reverse

Name: fabH [H]

Synonym: AM1_2844

Alternate gene names: 158335986

Gene position: 2888077-2886947 (Counterclockwise)

Preceding gene: 158335989

Following gene: 158335985

Centisome position: 44.41

GC content: 51.9

Gene sequence:

>1131_bases
ATGTCTCCCGGTCAAGCGGTTTTTATCACTGGAGTCGGCAAATTTTTGCCCGGAGAGCCCGTTGCTAATCAGGATATGGC
GGCGTATATCGGCAGTATTAGCAAACGTAGCTCTACCCTAGGATCTGCCATCCTACGAAAAAATGGGATTAAGCATCGCT
TCTATGCTCTCGATACGGAAGGGGGCTATCGATATACCAACGCATCGATGGCAGCCCATGCCATCCACGATGCCCTCAAG
CAAGCTCGCTGTCAGCCTGAACAGGTAGATTTACTGGCCACTAGTACGACCCAAGGGGATTATCTGGTGCCAGGTTTTGC
CAGTGCAGTCCATGGTGAATTGGGCATTCCCCCCTTAGCCATTTTTTCGTTTCAGAGTGTTTGTGCTAGCAGCCTGATGG
CGGTTAAAAATGCCTGGCTCAACGTCAAAGTGGGTGAGTCTCAGCTCGCCGTCGCCAGTGGCAGCGAATTTGCCAGCCGT
TGGTTTCGCCCTTCGGTTTATCGGCCTTTTTATGACGAAGCGGCTAGACCGGATCCGCAAATTGAATTTTTGCGGTGGAC
CCTGTCTGATGGGGCAGGAGCCTTGGTGCTAGAGCCCGGCCCTAAACCTGATGGCGTCTCTTTGCGGGTTGATTGGATTC
AATTTAAGTCCTTTGCCGATCGATTTCCGCCCTGTATGTATGCAGGGGCCAAAAGCAATACTGGGGCTGATGACCAGGGA
TGGGGATTATATGAGTCTCCTCAGGCTGCCTATGAAGCCGGTGCCATCGCCCTCAAGCAAGACTTTGAGATTCTCTATGC
CATGTTCCCCGTGTGGGTGGGCTACTATCTGGAGCTGCTAGAAAAGTACGATCTCGATCCCAACGCCATTGATTATTTTT
TACCTCACTACTCTTCCCACTCTTTGGGCGAGGAAATGAAGCGGCTGCTGCGCCGCACAGGAGCCATGATCGTGGAAGAG
AGATGGTGCAATAACCTAGAGCGCTATGGTAATACCGGGACGGCCTCCATCTTTATCATGCTAGAGGAGCTGGTCCAAAA
ACATCCATTGCAGCCCGGACAGCGGATCCTTTGTTTTGTGCCCGAAAGTGGGCGCTGTATTGCCGCCTTTATGCATTTAA
CTGTGGTGTAA

Upstream 100 bases:

>100_bases
GCGAGTCAACCCGAGACGAGCTATGATTCAGCAGTAGATGCTGCGACAGCATCGAGTATAAACCAGCCAACCATTACTGC
CCTCTGAGTTAGCTTTGCCT

Downstream 100 bases:

>100_bases
TTCCATGCAAACTCAACCCCGACTCCATAGCAACGTTACCCAGGCCCAGCGGGTGCTGCGCCAGCTCACCATGGTGTGGG
CCGATTTTGAGAGTCGGTTA

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MSPGQAVFITGVGKFLPGEPVANQDMAAYIGSISKRSSTLGSAILRKNGIKHRFYALDTEGGYRYTNASMAAHAIHDALK
QARCQPEQVDLLATSTTQGDYLVPGFASAVHGELGIPPLAIFSFQSVCASSLMAVKNAWLNVKVGESQLAVASGSEFASR
WFRPSVYRPFYDEAARPDPQIEFLRWTLSDGAGALVLEPGPKPDGVSLRVDWIQFKSFADRFPPCMYAGAKSNTGADDQG
WGLYESPQAAYEAGAIALKQDFEILYAMFPVWVGYYLELLEKYDLDPNAIDYFLPHYSSHSLGEEMKRLLRRTGAMIVEE
RWCNNLERYGNTGTASIFIMLEELVQKHPLQPGQRILCFVPESGRCIAAFMHLTVV

Sequences:

>Translated_376_residues
MSPGQAVFITGVGKFLPGEPVANQDMAAYIGSISKRSSTLGSAILRKNGIKHRFYALDTEGGYRYTNASMAAHAIHDALK
QARCQPEQVDLLATSTTQGDYLVPGFASAVHGELGIPPLAIFSFQSVCASSLMAVKNAWLNVKVGESQLAVASGSEFASR
WFRPSVYRPFYDEAARPDPQIEFLRWTLSDGAGALVLEPGPKPDGVSLRVDWIQFKSFADRFPPCMYAGAKSNTGADDQG
WGLYESPQAAYEAGAIALKQDFEILYAMFPVWVGYYLELLEKYDLDPNAIDYFLPHYSSHSLGEEMKRLLRRTGAMIVEE
RWCNNLERYGNTGTASIFIMLEELVQKHPLQPGQRILCFVPESGRCIAAFMHLTVV
>Mature_375_residues
SPGQAVFITGVGKFLPGEPVANQDMAAYIGSISKRSSTLGSAILRKNGIKHRFYALDTEGGYRYTNASMAAHAIHDALKQ
ARCQPEQVDLLATSTTQGDYLVPGFASAVHGELGIPPLAIFSFQSVCASSLMAVKNAWLNVKVGESQLAVASGSEFASRW
FRPSVYRPFYDEAARPDPQIEFLRWTLSDGAGALVLEPGPKPDGVSLRVDWIQFKSFADRFPPCMYAGAKSNTGADDQGW
GLYESPQAAYEAGAIALKQDFEILYAMFPVWVGYYLELLEKYDLDPNAIDYFLPHYSSHSLGEEMKRLLRRTGAMIVEER
WCNNLERYGNTGTASIFIMLEELVQKHPLQPGQRILCFVPESGRCIAAFMHLTVV

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 41518; Mature: 41387

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPGQAVFITGVGKFLPGEPVANQDMAAYIGSISKRSSTLGSAILRKNGIKHRFYALDTE
CCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
GGYRYTNASMAAHAIHDALKQARCQPEQVDLLATSTTQGDYLVPGFASAVHGELGIPPLA
CCEEECCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEECCCHHHHHCCCCCCCHHH
IFSFQSVCASSLMAVKNAWLNVKVGESQLAVASGSEFASRWFRPSVYRPFYDEAARPDPQ
HHHHHHHHHHHHHHHHHCEEEEEECCCEEEEECCHHHHHHHCCCCCCCCCHHHCCCCCCC
IEFLRWTLSDGAGALVLEPGPKPDGVSLRVDWIQFKSFADRFPPCMYAGAKSNTGADDQG
EEEEEEEECCCCCEEEECCCCCCCCCEEEEHHHHHHHHHHHCCCEEEECCCCCCCCCCCC
WGLYESPQAAYEAGAIALKQDFEILYAMFPVWVGYYLELLEKYDLDPNAIDYFLPHYSSH
CCCCCCCHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCC
SLGEEMKRLLRRTGAMIVEERWCNNLERYGNTGTASIFIMLEELVQKHPLQPGQRILCFV
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEE
PESGRCIAAFMHLTVV
CCCCCHHHHHHHHHCC
>Mature Secondary Structure 
SPGQAVFITGVGKFLPGEPVANQDMAAYIGSISKRSSTLGSAILRKNGIKHRFYALDTE
CCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
GGYRYTNASMAAHAIHDALKQARCQPEQVDLLATSTTQGDYLVPGFASAVHGELGIPPLA
CCEEECCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEECCCHHHHHCCCCCCCHHH
IFSFQSVCASSLMAVKNAWLNVKVGESQLAVASGSEFASRWFRPSVYRPFYDEAARPDPQ
HHHHHHHHHHHHHHHHHCEEEEEECCCEEEEECCHHHHHHHCCCCCCCCCHHHCCCCCCC
IEFLRWTLSDGAGALVLEPGPKPDGVSLRVDWIQFKSFADRFPPCMYAGAKSNTGADDQG
EEEEEEEECCCCCEEEECCCCCCCCCEEEEHHHHHHHHHHHCCCEEEECCCCCCCCCCCC
WGLYESPQAAYEAGAIALKQDFEILYAMFPVWVGYYLELLEKYDLDPNAIDYFLPHYSSH
CCCCCCCHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCC
SLGEEMKRLLRRTGAMIVEERWCNNLERYGNTGTASIFIMLEELVQKHPLQPGQRILCFV
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEE
PESGRCIAAFMHLTVV
CCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA