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The map label for this gene is rad50 [H]

Identifier: 158335965

GI number: 158335965

Start: 2864439

End: 2867180

Strand: Direct

Name: rad50 [H]

Synonym: AM1_2823

Alternate gene names: 158335965

Gene position: 2864439-2867180 (Clockwise)

Preceding gene: 158335964

Following gene: 158335967

Centisome position: 44.04

GC content: 51.53

Gene sequence:

>2742_bases
ATGGAAGTTCTCTCCGTTACGCTGAAAAACTTTAAGGCCCATCGCGATCGCTACTATGAATTCCGACCGGGGGCCAATGC
CATTTGCGGTGAAAATGGATCAGGGAAGACTAGCATCCTGGAAGCCATTGCCTGGGTTCTATTCGATCACAGTGAATATA
AACGAGCCGAACTGATTAGCGTCGGGGCTAAAAGTGCCCAGGCCATGGTCAGCTTTATCTCCCACTTGGATGGGCGGATC
TATGAGGTGCGTCGCTGTACCAGCCGTGGCTATGAGGTTCACGACCCCCAACTCAACCGCAAGCTAGAACTGAAAAAACT
GGATGATGTTCGCTGCTGGCTCTGTGAGCACTTGGGGGTGGGGGTCCATACGGAACTCGCCAAACTCTTTGCGGAAACCA
TTGGCATTCCCCAGGGCACCTTTACAGTAGATTTCCTCAAATCGGCGGGCGATCGCAAAAAGGTATTCGATCCCATCCTC
AAGGTGGAAGAGTATAAACAGGCCTACGATCAGGCCCAAAAATTAACCAGCTATGCCCAGGCCCAAGTCCAACAGCTAGA
ACAGCAATTACAGAGCTATGACCAGCAACTCGAAGGCTGGGAAGCACTGAAACAACAGAAGCTAGAGCTGGCCAACACCT
TGACTCAACAGCAGGCCCAGATGCAAACCCTGGCCCAGCAGTTGGCCGAGATGCAGACGGAACTCCAATATTTAAAGGCC
AAAGACCAGGCCATCCAAACCCTAGAAAAACAGGTTCAGCATCTCCAAACCCAATGGACCAGTAAACAGGAAATTCTCCA
GCTCTTAGAAGAGAATTGGCAGCAGGCCGATCAAGCCGTTCAGATTTGCCGTCAGCATCGGCCCCAATTTCAGGCCTATC
AAACAGCCCAAGAGTCCCTCAAAGACCTCGCTCAGCAGCAGAAGCAACGACAGCAACTGTTGCAAGAACGCGATCGCATC
CAAACTACCCTGCGGGATCAGCAAGTCTTGCTCTCCCAAAACCAAGGCCAGCTTTCCACCTTCGCCAAAATGGAAACAGA
ACTCCAGGACTGGCAAACCAAAGTTCCCCAGCAACAGCACCTCGAACAAGAAAAGACTACCTGCCAGCAAGCTCTACAAA
CCCTGGTCTCAGAACAACAGCAGCTGCAACGACTGCAAGAACTGCGCCACAAACAGCAGCAGCATCGGGAAACCCTCAGC
CAGACTATTAGCCAACTGGTCACCCTAGAGCCCCAAGTTCAAGCCATTCCGAACTTTGAAACTCAGCAGCAGCAGATTCA
AGAACGACTGGGACGGATTGCCGCCGCCCAGCAATTTGCCACAGAATTACAGACCTTAATCACCGAAGCTGAACCCCAAC
AGCAGCAATACCAACAACAAGTCGGCAAAGCCAAAGCGCTCCTCAAGAGCCTATCTCTCACCCAAGCCCAAACTACCCAA
CTCTCCACTCTCCTAGACCAGGGGGCGGCCCTCACCCACCAAATTATTCAGCAGCTACAAACGGCGTTTGCCGACATTAT
TGATCCGCAGGCGGTTACCAAGCTCAAGCAACAGCTTCAACAGATTAAAACCCAACTCAAAGCCGCCCAAAAAGCCCAGA
CCCAGTGGCTGATGTTAGAGGCCAAGCAGCAGCAGCTGACAGAGCTGGATCAAGGGATGGAGTCCTGGCAGCAGGAGTGC
GATCGCATCCAAGTCTCCCTCAACCAAGAACCCCAACTCCAAAGCCAGCTCAAACAGCTCAACACCCAGCTCACAGAGCT
AAACAACCCCCAGGGCCATGTCAGCATCCTAACCAAACAGTTGCAAGAGGCTGCCCAACTAGAAGCCGAAATTGCCCGTC
TCCAACAGGCTTGTCAACGGCATGAACAGTCCCTCACCACCGTTGATACCCAGATCAAAGCCTTGGGAGATCTGGAGGCC
CAAGTCGATGCCCAACAGCAGATCCAGCAGGAGCATCAGGAGGTCTATCAGCTCTATTTACGCCATCGAAATCAGGCTAA
TACGTTTAAAGAACTGGATCAGCAACGCCGAGGGGCAATGGCAACCCAAGCTCAGCTTCAAACTCAGCTCACAGCAGCTC
AAGCCCAATGGCAGGAGAAGCTGCACGTCCATAAACCGGAGCGTTTAGCAGAATTAAGTCAAACCTATGAACAACTGCAG
CGCCAGCATGATCAACTTCAGGGTGGGTTGGCACCGCAACAGGCACAGCTTCAATATTTAGACCAACAACTGCAAGCTAA
GCAAGCCCTTGCCCAAGAGCGTGATCAAATCCTAATCACCCTAGACAGCAAGCGCCAAATCTCACAGTTTGTCACGGACG
CTCGCAATATCTATAAGCAAAGCGGTCCCCGGATCACCAAATTCTATCTCACGGAAATTTCTTGGGAAGCCGATCGGTTG
TATCGAGAACTGCTAGATCGACCAGACGTGGCTTTACAGTGGACTGAAGATTATGAAATCCAGGTACAAGAACAGGGCCA
CTGGCGTACCTTCAAGAGCCTGTCTGGTGGTGAGCAAATGTGTGCGGCGCTAGCGGTGCGATTAGCCTTACTGAAAGTCC
TAGTGGATATCAATATTGCGTTTTTCGACGAGCCCACCACGAACATGGATGAACTGCGTCGTCGGCAGTTGGCCGAAGCC
TTAGGGCATCTCAAATCCTTTCATCAGCTATTTGTAATTAGCCATGATGACACCTTTGAGAGCGTTACAGAAAATATTAT
TCGGGTCGAGCGAGCCAGTTAA

Upstream 100 bases:

>100_bases
GCCAGCCCATAAGCGCTGCCCACAGTCTTCAAGTCAGAGCGTAAAAAAACCGCAATAATGATGGGAATGCTCATTTTCAT
GAGGTGCAACATCCTGCCGG

Downstream 100 bases:

>100_bases
AGCTTCAGGCTCAGAGGCTCTCACTCCTTTAAGGGGTCGTCCATTGGGTCACAGGTGCCGCAATTTGCTGCTGTTTTTGG
TAGGCCGCCACTTCTTGCTG

Product: RecF/RecN/SMC domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 913; Mature: 913

Protein sequence:

>913_residues
MEVLSVTLKNFKAHRDRYYEFRPGANAICGENGSGKTSILEAIAWVLFDHSEYKRAELISVGAKSAQAMVSFISHLDGRI
YEVRRCTSRGYEVHDPQLNRKLELKKLDDVRCWLCEHLGVGVHTELAKLFAETIGIPQGTFTVDFLKSAGDRKKVFDPIL
KVEEYKQAYDQAQKLTSYAQAQVQQLEQQLQSYDQQLEGWEALKQQKLELANTLTQQQAQMQTLAQQLAEMQTELQYLKA
KDQAIQTLEKQVQHLQTQWTSKQEILQLLEENWQQADQAVQICRQHRPQFQAYQTAQESLKDLAQQQKQRQQLLQERDRI
QTTLRDQQVLLSQNQGQLSTFAKMETELQDWQTKVPQQQHLEQEKTTCQQALQTLVSEQQQLQRLQELRHKQQQHRETLS
QTISQLVTLEPQVQAIPNFETQQQQIQERLGRIAAAQQFATELQTLITEAEPQQQQYQQQVGKAKALLKSLSLTQAQTTQ
LSTLLDQGAALTHQIIQQLQTAFADIIDPQAVTKLKQQLQQIKTQLKAAQKAQTQWLMLEAKQQQLTELDQGMESWQQEC
DRIQVSLNQEPQLQSQLKQLNTQLTELNNPQGHVSILTKQLQEAAQLEAEIARLQQACQRHEQSLTTVDTQIKALGDLEA
QVDAQQQIQQEHQEVYQLYLRHRNQANTFKELDQQRRGAMATQAQLQTQLTAAQAQWQEKLHVHKPERLAELSQTYEQLQ
RQHDQLQGGLAPQQAQLQYLDQQLQAKQALAQERDQILITLDSKRQISQFVTDARNIYKQSGPRITKFYLTEISWEADRL
YRELLDRPDVALQWTEDYEIQVQEQGHWRTFKSLSGGEQMCAALAVRLALLKVLVDINIAFFDEPTTNMDELRRRQLAEA
LGHLKSFHQLFVISHDDTFESVTENIIRVERAS

Sequences:

>Translated_913_residues
MEVLSVTLKNFKAHRDRYYEFRPGANAICGENGSGKTSILEAIAWVLFDHSEYKRAELISVGAKSAQAMVSFISHLDGRI
YEVRRCTSRGYEVHDPQLNRKLELKKLDDVRCWLCEHLGVGVHTELAKLFAETIGIPQGTFTVDFLKSAGDRKKVFDPIL
KVEEYKQAYDQAQKLTSYAQAQVQQLEQQLQSYDQQLEGWEALKQQKLELANTLTQQQAQMQTLAQQLAEMQTELQYLKA
KDQAIQTLEKQVQHLQTQWTSKQEILQLLEENWQQADQAVQICRQHRPQFQAYQTAQESLKDLAQQQKQRQQLLQERDRI
QTTLRDQQVLLSQNQGQLSTFAKMETELQDWQTKVPQQQHLEQEKTTCQQALQTLVSEQQQLQRLQELRHKQQQHRETLS
QTISQLVTLEPQVQAIPNFETQQQQIQERLGRIAAAQQFATELQTLITEAEPQQQQYQQQVGKAKALLKSLSLTQAQTTQ
LSTLLDQGAALTHQIIQQLQTAFADIIDPQAVTKLKQQLQQIKTQLKAAQKAQTQWLMLEAKQQQLTELDQGMESWQQEC
DRIQVSLNQEPQLQSQLKQLNTQLTELNNPQGHVSILTKQLQEAAQLEAEIARLQQACQRHEQSLTTVDTQIKALGDLEA
QVDAQQQIQQEHQEVYQLYLRHRNQANTFKELDQQRRGAMATQAQLQTQLTAAQAQWQEKLHVHKPERLAELSQTYEQLQ
RQHDQLQGGLAPQQAQLQYLDQQLQAKQALAQERDQILITLDSKRQISQFVTDARNIYKQSGPRITKFYLTEISWEADRL
YRELLDRPDVALQWTEDYEIQVQEQGHWRTFKSLSGGEQMCAALAVRLALLKVLVDINIAFFDEPTTNMDELRRRQLAEA
LGHLKSFHQLFVISHDDTFESVTENIIRVERAS
>Mature_913_residues
MEVLSVTLKNFKAHRDRYYEFRPGANAICGENGSGKTSILEAIAWVLFDHSEYKRAELISVGAKSAQAMVSFISHLDGRI
YEVRRCTSRGYEVHDPQLNRKLELKKLDDVRCWLCEHLGVGVHTELAKLFAETIGIPQGTFTVDFLKSAGDRKKVFDPIL
KVEEYKQAYDQAQKLTSYAQAQVQQLEQQLQSYDQQLEGWEALKQQKLELANTLTQQQAQMQTLAQQLAEMQTELQYLKA
KDQAIQTLEKQVQHLQTQWTSKQEILQLLEENWQQADQAVQICRQHRPQFQAYQTAQESLKDLAQQQKQRQQLLQERDRI
QTTLRDQQVLLSQNQGQLSTFAKMETELQDWQTKVPQQQHLEQEKTTCQQALQTLVSEQQQLQRLQELRHKQQQHRETLS
QTISQLVTLEPQVQAIPNFETQQQQIQERLGRIAAAQQFATELQTLITEAEPQQQQYQQQVGKAKALLKSLSLTQAQTTQ
LSTLLDQGAALTHQIIQQLQTAFADIIDPQAVTKLKQQLQQIKTQLKAAQKAQTQWLMLEAKQQQLTELDQGMESWQQEC
DRIQVSLNQEPQLQSQLKQLNTQLTELNNPQGHVSILTKQLQEAAQLEAEIARLQQACQRHEQSLTTVDTQIKALGDLEA
QVDAQQQIQQEHQEVYQLYLRHRNQANTFKELDQQRRGAMATQAQLQTQLTAAQAQWQEKLHVHKPERLAELSQTYEQLQ
RQHDQLQGGLAPQQAQLQYLDQQLQAKQALAQERDQILITLDSKRQISQFVTDARNIYKQSGPRITKFYLTEISWEADRL
YRELLDRPDVALQWTEDYEIQVQEQGHWRTFKSLSGGEQMCAALAVRLALLKVLVDINIAFFDEPTTNMDELRRRQLAEA
LGHLKSFHQLFVISHDDTFESVTENIIRVERAS

Specific function: Involved in DNA double-strand break repair (DSBR). The rad50/mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific 3'-5' exonuclease activity. Rad50 provides an ATP-dependent control of mre11 by unwinding and

COG id: COG0419

COG function: function code L; ATPase involved in DNA repair

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 zinc-hook domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR022982
- InterPro:   IPR007517
- InterPro:   IPR003395
- InterPro:   IPR013134 [H]

Pfam domain/function: PF04423 Rad50_zn_hook; PF02463 SMC_N [H]

EC number: NA

Molecular weight: Translated: 105639; Mature: 105639

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVLSVTLKNFKAHRDRYYEFRPGANAICGENGSGKTSILEAIAWVLFDHSEYKRAELIS
CCHHHHHHHHHHHHHHHCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHH
VGAKSAQAMVSFISHLDGRIYEVRRCTSRGYEVHDPQLNRKLELKKLDDVRCWLCEHLGV
HHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
GVHTELAKLFAETIGIPQGTFTVDFLKSAGDRKKVFDPILKVEEYKQAYDQAQKLTSYAQ
CHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQVQQLEQQLQSYDQQLEGWEALKQQKLELANTLTQQQAQMQTLAQQLAEMQTELQYLKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KDQAIQTLEKQVQHLQTQWTSKQEILQLLEENWQQADQAVQICRQHRPQFQAYQTAQESL
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
KDLAQQQKQRQQLLQERDRIQTTLRDQQVLLSQNQGQLSTFAKMETELQDWQTKVPQQQH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHH
LEQEKTTCQQALQTLVSEQQQLQRLQELRHKQQQHRETLSQTISQLVTLEPQVQAIPNFE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCC
TQQQQIQERLGRIAAAQQFATELQTLITEAEPQQQQYQQQVGKAKALLKSLSLTQAQTTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSTLLDQGAALTHQIIQQLQTAFADIIDPQAVTKLKQQLQQIKTQLKAAQKAQTQWLMLE
HHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKQQQLTELDQGMESWQQECDRIQVSLNQEPQLQSQLKQLNTQLTELNNPQGHVSILTKQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
LQEAAQLEAEIARLQQACQRHEQSLTTVDTQIKALGDLEAQVDAQQQIQQEHQEVYQLYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RHRNQANTFKELDQQRRGAMATQAQLQTQLTAAQAQWQEKLHVHKPERLAELSQTYEQLQ
HHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RQHDQLQGGLAPQQAQLQYLDQQLQAKQALAQERDQILITLDSKRQISQFVTDARNIYKQ
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHH
SGPRITKFYLTEISWEADRLYRELLDRPDVALQWTEDYEIQVQEQGHWRTFKSLSGGEQM
CCCCEEHHHHHHHCCHHHHHHHHHHCCCCCEEEECCCCEEEEECCCCHHHHHHCCCHHHH
CAALAVRLALLKVLVDINIAFFDEPTTNMDELRRRQLAEALGHLKSFHQLFVISHDDTFE
HHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHH
SVTENIIRVERAS
HHHHHHHHHHCCC
>Mature Secondary Structure
MEVLSVTLKNFKAHRDRYYEFRPGANAICGENGSGKTSILEAIAWVLFDHSEYKRAELIS
CCHHHHHHHHHHHHHHHCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHH
VGAKSAQAMVSFISHLDGRIYEVRRCTSRGYEVHDPQLNRKLELKKLDDVRCWLCEHLGV
HHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
GVHTELAKLFAETIGIPQGTFTVDFLKSAGDRKKVFDPILKVEEYKQAYDQAQKLTSYAQ
CHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQVQQLEQQLQSYDQQLEGWEALKQQKLELANTLTQQQAQMQTLAQQLAEMQTELQYLKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KDQAIQTLEKQVQHLQTQWTSKQEILQLLEENWQQADQAVQICRQHRPQFQAYQTAQESL
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
KDLAQQQKQRQQLLQERDRIQTTLRDQQVLLSQNQGQLSTFAKMETELQDWQTKVPQQQH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHH
LEQEKTTCQQALQTLVSEQQQLQRLQELRHKQQQHRETLSQTISQLVTLEPQVQAIPNFE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCC
TQQQQIQERLGRIAAAQQFATELQTLITEAEPQQQQYQQQVGKAKALLKSLSLTQAQTTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSTLLDQGAALTHQIIQQLQTAFADIIDPQAVTKLKQQLQQIKTQLKAAQKAQTQWLMLE
HHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKQQQLTELDQGMESWQQECDRIQVSLNQEPQLQSQLKQLNTQLTELNNPQGHVSILTKQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
LQEAAQLEAEIARLQQACQRHEQSLTTVDTQIKALGDLEAQVDAQQQIQQEHQEVYQLYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RHRNQANTFKELDQQRRGAMATQAQLQTQLTAAQAQWQEKLHVHKPERLAELSQTYEQLQ
HHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RQHDQLQGGLAPQQAQLQYLDQQLQAKQALAQERDQILITLDSKRQISQFVTDARNIYKQ
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHH
SGPRITKFYLTEISWEADRLYRELLDRPDVALQWTEDYEIQVQEQGHWRTFKSLSGGEQM
CCCCEEHHHHHHHCCHHHHHHHHHHCCCCCEEEECCCCEEEEECCCCHHHHHHCCCHHHH
CAALAVRLALLKVLVDINIAFFDEPTTNMDELRRRQLAEALGHLKSFHQLFVISHDDTFE
HHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHH
SVTENIIRVERAS
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]