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The map label for this gene is pdxJ

Identifier: 158335900

GI number: 158335900

Start: 2792766

End: 2793488

Strand: Direct

Name: pdxJ

Synonym: AM1_2758

Alternate gene names: 158335900

Gene position: 2792766-2793488 (Clockwise)

Preceding gene: 158335899

Following gene: 158335902

Centisome position: 42.94

GC content: 52.84

Gene sequence:

>723_bases
ATGCCTACCCTTGGTGTCAATATCGATCATGTGGCGACGATTCGCCAAGCCCGTCGCACTGTGGAACCGGATCCCGTCGC
GGCAGCCGTATTAGCTGAATTAGCGGGAGCCGATGGTATAACAGTCCATTTACGAGAAGATCGGCGGCATATTCAGGATC
GAGATGTCGAGGTACTGCGGAAAACGGTTCGTACCCATTTGAATTTGGAAATGGCGGCGACAGCAGAAATGGTTGAAATC
GCACTTCGTATCCAACCGGATTATGTCACCCTAGTGCCGGAAAAGCGGGAGGAAGTGACCACGGAAGGAGGGCTAGATGT
CATTGGTCAGCAAACCCATATGGCGGATGTGGTCCAGACCTTACAAGCCGCTAATATTCCCGTCAGTCTGTTTATTGATG
CTGATGCTGCCCAGATTGAAGCAGCCGCTCAGGTGCAGGCCAAGTTTATTGAACTGCATACGGGGACTTACGCTGAAGCC
AAGGGTGAGGCCCAGCAGACCCAGGAGTTGGACGTGTTGAAACAGGGATGTGATCGCGCCGCTGCATTAGGGCTACGAGT
CAATGCAGGACATGGTTTGACCTATTGGAATACCTATCCTGTGGCCTGTCTACCGGGGATGGAAGAACTGAATATTGGCC
ACACGATTATTAGTCGGTCGGTGTTGGTGGGTTTGGAACGAGCCGTGCGGGAAATGAAGGACGTGATTGCGGGTCGAGGT
TAG

Upstream 100 bases:

>100_bases
GGGTACTGTTCAAGCCGAGAACTCACCAACGCTCTATCCCATGCTTCGGCACCCGCAATAACCTCTATAATTAATCTTCC
CCCTAGCCAGGAGTGTTATC

Downstream 100 bases:

>100_bases
GTTTGCAGCAGTTGCTGAGCGGAGGTAATCAGCTGCTGCGTTTTTCCGATATCCAATTGGCCTTGGTGGTTCAGGGGAAC
GGCAACATCTGGAGAAAGCC

Product: pyridoxine 5'-phosphate synthase

Products: NA

Alternate protein names: PNP synthase

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MPTLGVNIDHVATIRQARRTVEPDPVAAAVLAELAGADGITVHLREDRRHIQDRDVEVLRKTVRTHLNLEMAATAEMVEI
ALRIQPDYVTLVPEKREEVTTEGGLDVIGQQTHMADVVQTLQAANIPVSLFIDADAAQIEAAAQVQAKFIELHTGTYAEA
KGEAQQTQELDVLKQGCDRAAALGLRVNAGHGLTYWNTYPVACLPGMEELNIGHTIISRSVLVGLERAVREMKDVIAGRG

Sequences:

>Translated_240_residues
MPTLGVNIDHVATIRQARRTVEPDPVAAAVLAELAGADGITVHLREDRRHIQDRDVEVLRKTVRTHLNLEMAATAEMVEI
ALRIQPDYVTLVPEKREEVTTEGGLDVIGQQTHMADVVQTLQAANIPVSLFIDADAAQIEAAAQVQAKFIELHTGTYAEA
KGEAQQTQELDVLKQGCDRAAALGLRVNAGHGLTYWNTYPVACLPGMEELNIGHTIISRSVLVGLERAVREMKDVIAGRG
>Mature_239_residues
PTLGVNIDHVATIRQARRTVEPDPVAAAVLAELAGADGITVHLREDRRHIQDRDVEVLRKTVRTHLNLEMAATAEMVEIA
LRIQPDYVTLVPEKREEVTTEGGLDVIGQQTHMADVVQTLQAANIPVSLFIDADAAQIEAAAQVQAKFIELHTGTYAEAK
GEAQQTQELDVLKQGCDRAAALGLRVNAGHGLTYWNTYPVACLPGMEELNIGHTIISRSVLVGLERAVREMKDVIAGRG

Specific function: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate

COG id: COG0854

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:
GO:0003824: Pyridoxine 5'-phosphate synthase
GO:0005737: Pyridoxine 5'-phosphate synthase
GO:0008152: Pyridoxine 5'-phosphate synthase
GO:0008615: Pyridoxine 5'-phosphate synthase
GO:0016740: Pyridoxine 5'-phosphate synthase
GO:0033856: Pyridoxine 5'-phosphate synthase

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP synthase family

Homologues:

Organism=Escherichia coli, GI1788917, Length=233, Percent_Identity=62.2317596566524, Blast_Score=288, Evalue=3e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXJ_ACAM1 (B0C977)

Other databases:

- EMBL:   CP000828
- RefSeq:   YP_001517074.1
- ProteinModelPortal:   B0C977
- SMR:   B0C977
- GeneID:   5681566
- GenomeReviews:   CP000828_GR
- KEGG:   amr:AM1_2758
- HOGENOM:   HBG299314
- OMA:   AGHGLNY
- ProtClustDB:   PRK05265
- BioCyc:   AMAR329726:AM1_2758-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00279
- InterPro:   IPR013785
- InterPro:   IPR004569
- Gene3D:   G3DSA:3.20.20.70
- TIGRFAMs:   TIGR00559

Pfam domain/function: PF03740 PdxJ; SSF63892 PyrdxlP_synth_PdxJ

EC number: =2.6.99.2

Molecular weight: Translated: 26106; Mature: 25975

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: ACT_SITE 43-43 ACT_SITE 70-70 ACT_SITE 191-191 BINDING 7-7 BINDING 18-18 BINDING 45-45 BINDING 50-50 BINDING 100-100 BINDING 192-192

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTLGVNIDHVATIRQARRTVEPDPVAAAVLAELAGADGITVHLREDRRHIQDRDVEVLR
CCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEECHHHHHCCCCHHHHH
KTVRTHLNLEMAATAEMVEIALRIQPDYVTLVPEKREEVTTEGGLDVIGQQTHMADVVQT
HHHHHHCCHHHHHHHHHHHHHEEECCCEEEECCCCHHHHCCCCCCHHHCCHHHHHHHHHH
LQAANIPVSLFIDADAAQIEAAAQVQAKFIELHTGTYAEAKGEAQQTQELDVLKQGCDRA
HHHCCCCEEEEECCCHHHHHHHHHHHHHHHEEECCCCHHCCCCHHHHHHHHHHHHCCCHH
AALGLRVNAGHGLTYWNTYPVACLPGMEELNIGHTIISRSVLVGLERAVREMKDVIAGRG
HHHCEEEECCCCEEEECCCCEEECCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PTLGVNIDHVATIRQARRTVEPDPVAAAVLAELAGADGITVHLREDRRHIQDRDVEVLR
CCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEECHHHHHCCCCHHHHH
KTVRTHLNLEMAATAEMVEIALRIQPDYVTLVPEKREEVTTEGGLDVIGQQTHMADVVQT
HHHHHHCCHHHHHHHHHHHHHEEECCCEEEECCCCHHHHCCCCCCHHHCCHHHHHHHHHH
LQAANIPVSLFIDADAAQIEAAAQVQAKFIELHTGTYAEAKGEAQQTQELDVLKQGCDRA
HHHCCCCEEEEECCCHHHHHHHHHHHHHHHEEECCCCHHCCCCHHHHHHHHHHHHCCCHH
AALGLRVNAGHGLTYWNTYPVACLPGMEELNIGHTIISRSVLVGLERAVREMKDVIAGRG
HHHCEEEECCCCEEEECCCCEEECCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA