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The map label for this gene is nahR [H]

Identifier: 158335812

GI number: 158335812

Start: 2704926

End: 2705843

Strand: Reverse

Name: nahR [H]

Synonym: AM1_2663

Alternate gene names: 158335812

Gene position: 2705843-2704926 (Counterclockwise)

Preceding gene: 158335813

Following gene: 158335810

Centisome position: 41.6

GC content: 45.21

Gene sequence:

>918_bases
GTGCATAATCAGATCGATCTCAATCTACTCCATATCTTTGAAGCTGTGATGATGGAGTTAAATGTTAGCCGTGCTGCTGA
ACGATTAAATATGACTCAACCTGCTGTGAGTCATGCGCTTCGAAGGCTCAGACGCATTACTAATGATGAACTGTTTTTGA
AAGTTCCGAGCGGCGTGAGTCCAACGCCTAAAGCTCTAGAACTCTGGGGACCGATTCGTGAGGGGCTAGTGCATATTCGA
CTAGCGCTCTCGCCACCTTCATTTGAGCCCTTTTCATCAATGCAGACGTTTACATTGGCAATGGCTGATTACTCGGTAGC
TCTTTTTTTACCAAAGTTGCTACCAATTTTGGCTCATTCCGCACCTAATATAAATATCCGCATCGTTCCGAACACAAACA
TTAATGCGGCGAAGCTGCTCGAACAATCTGAAATTGATCTGGCCATGGGGCGATTTTATCGCTCGACCGTTCGGCTCAGA
GTGCAGGAGATTATAGGTGATCGCTACATCTGCATCATGCGTAAAGACCATCCTTTAGCCCATAAACGACTGACTCTCAA
GCAATACATCAAGGCTGATCATCTCCTTGTAACTTTAACTGGAGAGGCAACAGGACTGGTTGATAAACAACTGAGGGAGA
TGGACTTGAGTCGCCGTATTGCCCTAACGGTTAATCAGTTTACGCTGGTTCCTGAACTGATTGCAGGTTCTGATTTAATC
TCAGCAATTCCTCTCCGTATGGTGGAGCGGAATCCTTTTAGAACGGACTTACACATCACTGAGTTGCCTCTCAAAATAGC
TCCTGCTTTCTTGCAAATGATGTGGCACGAGCGTAGTCAGGTCGATCCAGCCCATGAATGGTTAAGGAGTCAACTGTTTG
AAATTGTTCAAGATTTACCAACTGTCACAATCCCTTAA

Upstream 100 bases:

>100_bases
TCTCTTGGCTCCAGCGGATTTACCGCGTTGCCATATTTCGACTATAAAAGGGCTGTATTATAATGTCTAATTCATGATAA
ATATAAACATTATGAATTCA

Downstream 100 bases:

>100_bases
GAGGACAGAAGTAGATCTCCCCATAGGTCGTTTATCATCTAACGTTCATGAAATTGTTGTTATGTCTGTACTGAGTCTTT
TGCACACATTATTCATACCT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MHNQIDLNLLHIFEAVMMELNVSRAAERLNMTQPAVSHALRRLRRITNDELFLKVPSGVSPTPKALELWGPIREGLVHIR
LALSPPSFEPFSSMQTFTLAMADYSVALFLPKLLPILAHSAPNINIRIVPNTNINAAKLLEQSEIDLAMGRFYRSTVRLR
VQEIIGDRYICIMRKDHPLAHKRLTLKQYIKADHLLVTLTGEATGLVDKQLREMDLSRRIALTVNQFTLVPELIAGSDLI
SAIPLRMVERNPFRTDLHITELPLKIAPAFLQMMWHERSQVDPAHEWLRSQLFEIVQDLPTVTIP

Sequences:

>Translated_305_residues
MHNQIDLNLLHIFEAVMMELNVSRAAERLNMTQPAVSHALRRLRRITNDELFLKVPSGVSPTPKALELWGPIREGLVHIR
LALSPPSFEPFSSMQTFTLAMADYSVALFLPKLLPILAHSAPNINIRIVPNTNINAAKLLEQSEIDLAMGRFYRSTVRLR
VQEIIGDRYICIMRKDHPLAHKRLTLKQYIKADHLLVTLTGEATGLVDKQLREMDLSRRIALTVNQFTLVPELIAGSDLI
SAIPLRMVERNPFRTDLHITELPLKIAPAFLQMMWHERSQVDPAHEWLRSQLFEIVQDLPTVTIP
>Mature_305_residues
MHNQIDLNLLHIFEAVMMELNVSRAAERLNMTQPAVSHALRRLRRITNDELFLKVPSGVSPTPKALELWGPIREGLVHIR
LALSPPSFEPFSSMQTFTLAMADYSVALFLPKLLPILAHSAPNINIRIVPNTNINAAKLLEQSEIDLAMGRFYRSTVRLR
VQEIIGDRYICIMRKDHPLAHKRLTLKQYIKADHLLVTLTGEATGLVDKQLREMDLSRRIALTVNQFTLVPELIAGSDLI
SAIPLRMVERNPFRTDLHITELPLKIAPAFLQMMWHERSQVDPAHEWLRSQLFEIVQDLPTVTIP

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=295, Percent_Identity=28.8135593220339, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI87081766, Length=244, Percent_Identity=29.0983606557377, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790147, Length=291, Percent_Identity=25.7731958762887, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789204, Length=242, Percent_Identity=24.3801652892562, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786820, Length=278, Percent_Identity=24.8201438848921, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34785; Mature: 34785

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHNQIDLNLLHIFEAVMMELNVSRAAERLNMTQPAVSHALRRLRRITNDELFLKVPSGVS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCCC
PTPKALELWGPIREGLVHIRLALSPPSFEPFSSMQTFTLAMADYSVALFLPKLLPILAHS
CCCHHHHHHHHHHHCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
APNINIRIVPNTNINAAKLLEQSEIDLAMGRFYRSTVRLRVQEIIGDRYICIMRKDHPLA
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCH
HKRLTLKQYIKADHLLVTLTGEATGLVDKQLREMDLSRRIALTVNQFTLVPELIAGSDLI
HHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCEEEEEEHHHHHHHHHHCCCHHH
SAIPLRMVERNPFRTDLHITELPLKIAPAFLQMMWHERSQVDPAHEWLRSQLFEIVQDLP
HHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
TVTIP
CCCCC
>Mature Secondary Structure
MHNQIDLNLLHIFEAVMMELNVSRAAERLNMTQPAVSHALRRLRRITNDELFLKVPSGVS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCCC
PTPKALELWGPIREGLVHIRLALSPPSFEPFSSMQTFTLAMADYSVALFLPKLLPILAHS
CCCHHHHHHHHHHHCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
APNINIRIVPNTNINAAKLLEQSEIDLAMGRFYRSTVRLRVQEIIGDRYICIMRKDHPLA
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCH
HKRLTLKQYIKADHLLVTLTGEATGLVDKQLREMDLSRRIALTVNQFTLVPELIAGSDLI
HHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCEEEEEEHHHHHHHHHHCCCHHH
SAIPLRMVERNPFRTDLHITELPLKIAPAFLQMMWHERSQVDPAHEWLRSQLFEIVQDLP
HHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
TVTIP
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]