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The map label for this gene is yfhR [C]

Identifier: 158335789

GI number: 158335789

Start: 2679755

End: 2680705

Strand: Direct

Name: yfhR [C]

Synonym: AM1_2640

Alternate gene names: 158335789

Gene position: 2679755-2680705 (Clockwise)

Preceding gene: 158335788

Following gene: 158335793

Centisome position: 41.2

GC content: 50.47

Gene sequence:

>951_bases
TTGCTACTCCCCTCCAACAATCCCTGGACCTCTAGATTACGACAGCTCGGCATTCGGCTGGCCCAAGGTTTAGTGGCTTG
CACCCTCTTGGTCTATTCAGGGATCTGTATCTTCTTTTTTGTGCGGCAAGAAGCACTACTTTACGATTCTAAGCTAACTC
TGGAAACGGTACCCAGCGATCAACCCTTTCAACTACCGTTCCAAACTGTCAAAATCCCCGTGGGGTCAAGCTCTGAGCAC
CTAAATAGTTGGTGGGTACCTGCCCCTCAATCCTCCGAAGACACCATTGCTCTACCCGAAGAACCTCACGATATCCTGAC
TGAACCGAAAGTGATTCTGTATTTCAACGGACGGGCAGGCAATAAGGGGTCTCGAAGTCACTTAGAACGCGTCAAAGGTT
TCCGTCAGCTGGGCTTTTCTGTCTTGCTCGTTGATTATCGGGGCTATGGGAATAGCTCACCTCGCCAACCTAGTGAGGCC
AGCTTGTACGAAGATAGCCAAGCCGCCTGGCGCTATCTGACTCAAACACGGAGGATGGCTGCCCACCAAATTGTGATTTA
TGGCGAATCCTTAGGTGGAGCCGTCGCCCTCGATTTAGCGGTTAAGCAGCCCAATGCAGCGGGCGTTATTGTCCAAAGTT
CTTTTACGACGCTACCCGCAGCAGCGAGGGAGATGGACTGGTTTCGATACCTTCCTGTGGATTGGATTCTGACCCAACGA
TTTAATTCCCTAGCTAAGGTGCGGTCTTTGAAAACCCCCGTCCTTTTCCTCCATGGCACCGCAGATCAGATTGTGCCGGT
ATGGATGAGTCATAGGCTTTATCAGGCAGTGCCCTCAGAGACCCCTAAAGAATTAGTGATAGTGCCCGATGCTAGCCATT
TCCGTATTTATCGTCCAGGTCAGCATTCTTATCTGAAAGCCATACAGCGCTTGGTAACCAAGATGCAATAA

Upstream 100 bases:

>100_bases
TGTCCCTCTACGATATCAGCAGAAATGTGACATCAGCTTCTAGGGTTGAACTCCAGCGCCTAGGAGTAATGATGGTTGTT
TTAAACTCTCCCTGCGGACA

Downstream 100 bases:

>100_bases
CGCTACTTCCCTCTCCATTGATGGGCCTTGAGCTGAGTACTGAACTTCGTGCTGAACTCATCAAGACTGAGAAAGCTGTC
TCATAGTGGTCTGCACCTTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MLLPSNNPWTSRLRQLGIRLAQGLVACTLLVYSGICIFFFVRQEALLYDSKLTLETVPSDQPFQLPFQTVKIPVGSSSEH
LNSWWVPAPQSSEDTIALPEEPHDILTEPKVILYFNGRAGNKGSRSHLERVKGFRQLGFSVLLVDYRGYGNSSPRQPSEA
SLYEDSQAAWRYLTQTRRMAAHQIVIYGESLGGAVALDLAVKQPNAAGVIVQSSFTTLPAAAREMDWFRYLPVDWILTQR
FNSLAKVRSLKTPVLFLHGTADQIVPVWMSHRLYQAVPSETPKELVIVPDASHFRIYRPGQHSYLKAIQRLVTKMQ

Sequences:

>Translated_316_residues
MLLPSNNPWTSRLRQLGIRLAQGLVACTLLVYSGICIFFFVRQEALLYDSKLTLETVPSDQPFQLPFQTVKIPVGSSSEH
LNSWWVPAPQSSEDTIALPEEPHDILTEPKVILYFNGRAGNKGSRSHLERVKGFRQLGFSVLLVDYRGYGNSSPRQPSEA
SLYEDSQAAWRYLTQTRRMAAHQIVIYGESLGGAVALDLAVKQPNAAGVIVQSSFTTLPAAAREMDWFRYLPVDWILTQR
FNSLAKVRSLKTPVLFLHGTADQIVPVWMSHRLYQAVPSETPKELVIVPDASHFRIYRPGQHSYLKAIQRLVTKMQ
>Mature_316_residues
MLLPSNNPWTSRLRQLGIRLAQGLVACTLLVYSGICIFFFVRQEALLYDSKLTLETVPSDQPFQLPFQTVKIPVGSSSEH
LNSWWVPAPQSSEDTIALPEEPHDILTEPKVILYFNGRAGNKGSRSHLERVKGFRQLGFSVLLVDYRGYGNSSPRQPSEA
SLYEDSQAAWRYLTQTRRMAAHQIVIYGESLGGAVALDLAVKQPNAAGVIVQSSFTTLPAAAREMDWFRYLPVDWILTQR
FNSLAKVRSLKTPVLFLHGTADQIVPVWMSHRLYQAVPSETPKELVIVPDASHFRIYRPGQHSYLKAIQRLVTKMQ

Specific function: Unknown

COG id: COG1073

COG function: function code R; Hydrolases of the alpha/beta superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To S.pombe bem46 and yeast YNL320w [H]

Homologues:

Organism=Homo sapiens, GI49355781, Length=209, Percent_Identity=34.9282296650718, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI24308097, Length=193, Percent_Identity=27.979274611399, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI109689718, Length=193, Percent_Identity=27.979274611399, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI71051602, Length=204, Percent_Identity=29.9019607843137, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI71051600, Length=204, Percent_Identity=29.9019607843137, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI194306564, Length=204, Percent_Identity=30.8823529411765, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI194306562, Length=204, Percent_Identity=30.8823529411765, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI32528310, Length=180, Percent_Identity=27.7777777777778, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI151301175, Length=206, Percent_Identity=27.6699029126214, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI32451492, Length=180, Percent_Identity=27.7777777777778, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI226510965, Length=221, Percent_Identity=26.6968325791855, Blast_Score=87, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17566318, Length=187, Percent_Identity=25.668449197861, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI71988362, Length=183, Percent_Identity=30.6010928961749, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17532877, Length=155, Percent_Identity=31.6129032258064, Blast_Score=68, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6324009, Length=215, Percent_Identity=32.5581395348837, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17137566, Length=276, Percent_Identity=31.5217391304348, Blast_Score=107, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24655464, Length=206, Percent_Identity=30.0970873786408, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24655467, Length=206, Percent_Identity=30.0970873786408, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281362521, Length=167, Percent_Identity=31.7365269461078, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI281362519, Length=167, Percent_Identity=31.7365269461078, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI28571878, Length=167, Percent_Identity=31.7365269461078, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002925 [H]

Pfam domain/function: PF01738 DLH [H]

EC number: NA

Molecular weight: Translated: 35622; Mature: 35622

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLPSNNPWTSRLRQLGIRLAQGLVACTLLVYSGICIFFFVRQEALLYDSKLTLETVPSD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
QPFQLPFQTVKIPVGSSSEHLNSWWVPAPQSSEDTIALPEEPHDILTEPKVILYFNGRAG
CCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHHCCCEEEEEECCCCC
NKGSRSHLERVKGFRQLGFSVLLVDYRGYGNSSPRQPSEASLYEDSQAAWRYLTQTRRMA
CCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHH
AHQIVIYGESLGGAVALDLAVKQPNAAGVIVQSSFTTLPAAAREMDWFRYLPVDWILTQR
HEEEEEEECCCCCEEEEEEEEECCCCCEEEEECCCCCCCHHHHHCCHHHHCCHHHHHHHH
FNSLAKVRSLKTPVLFLHGTADQIVPVWMSHRLYQAVPSETPKELVIVPDASHFRIYRPG
HHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEECCC
QHSYLKAIQRLVTKMQ
CHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLLPSNNPWTSRLRQLGIRLAQGLVACTLLVYSGICIFFFVRQEALLYDSKLTLETVPSD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
QPFQLPFQTVKIPVGSSSEHLNSWWVPAPQSSEDTIALPEEPHDILTEPKVILYFNGRAG
CCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHHCCCEEEEEECCCCC
NKGSRSHLERVKGFRQLGFSVLLVDYRGYGNSSPRQPSEASLYEDSQAAWRYLTQTRRMA
CCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHH
AHQIVIYGESLGGAVALDLAVKQPNAAGVIVQSSFTTLPAAAREMDWFRYLPVDWILTQR
HEEEEEEECCCCCEEEEEEEEECCCCCEEEEECCCCCCCHHHHHCCHHHHCCHHHHHHHH
FNSLAKVRSLKTPVLFLHGTADQIVPVWMSHRLYQAVPSETPKELVIVPDASHFRIYRPG
HHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEECCC
QHSYLKAIQRLVTKMQ
CHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]