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The map label for this gene is bioD [H]

Identifier: 158335776

GI number: 158335776

Start: 2666513

End: 2667238

Strand: Reverse

Name: bioD [H]

Synonym: AM1_2626

Alternate gene names: 158335776

Gene position: 2667238-2666513 (Counterclockwise)

Preceding gene: 158335777

Following gene: 158335774

Centisome position: 41.01

GC content: 47.52

Gene sequence:

>726_bases
GTGGCACAAACTCTTTTAATTAGTGGTTCAGATACAGAAATTGGCAAAACCATTGTTACATCTGCCTTATTGGCCTATTG
GCAGATCTATAGACCAAATGAAAAGATTGCAGTCTGTAAGCCAGTACAATCTGGATTGGGAGATCGGGAATGGTATACCG
AGGTCTTTGATCTGAACCAGCCCCCGGAAACCTTGAACCCTCTTTATTTTGAGCAACCGCTAGCGCCTCCCTTGGCGGCA
AAACGAGCTGGTCAGGTTGTGGATTTATTACCTGCTTGGCAAGCGGTTCAACAGTTGCAGTCTCAGTTTGACTGGGTGTT
AGTTGAAGGGGTTGGTAGTTTAGGCTCTCCAGTGACAGATGAGTTGATTGTGGCGGATATTGCTCGAGATTGGCGATTGC
CCATTGTCTTAGTGGTGCCGATTAGATTGGGATGTGTGGGGCAAGCGGTTGCTCATGTGGCTTTAGCACGACAGTTTGGA
CTGGATGTAAAAGGCATTGTTTTGAATGCTACGGGGGTATTATCCACGGAAGAAATTCAGCAATGGGCACCGGCTGATAT
GATACAAGCCTTGACCCAGGTGCCAGTGATTGGACAGGTGCCTCATTTGTCTGATCCAACGAATCGAGCAGCACTGGCTG
AGGTAGCCTCTGGGTTAGATTTAGAGATGTTAGGCTCGCTTAGCTATGCGACTCAAGATTGCCAGCGAAACTTCCAGGAT
AAATAG

Upstream 100 bases:

>100_bases
TTCGATCTGTTAGGGTTGGCAGCAGCCATATTCTCCCTATCGGTCAGTTATTGGTTAGTGTGTCAACTTAAAAAATAGTC
AATCTAAGGATATTAGTGCT

Downstream 100 bases:

>100_bases
AGAGGTAACTGGTAAAACTCTGCCAAAACCCATAAGGCGATTAAGCCATGGGTGAAGCCCACGATGCCAATCCAGAGTAA
CGGAAAGGAATGGGCAGAGC

Product: dithiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MAQTLLISGSDTEIGKTIVTSALLAYWQIYRPNEKIAVCKPVQSGLGDREWYTEVFDLNQPPETLNPLYFEQPLAPPLAA
KRAGQVVDLLPAWQAVQQLQSQFDWVLVEGVGSLGSPVTDELIVADIARDWRLPIVLVVPIRLGCVGQAVAHVALARQFG
LDVKGIVLNATGVLSTEEIQQWAPADMIQALTQVPVIGQVPHLSDPTNRAALAEVASGLDLEMLGSLSYATQDCQRNFQD
K

Sequences:

>Translated_241_residues
MAQTLLISGSDTEIGKTIVTSALLAYWQIYRPNEKIAVCKPVQSGLGDREWYTEVFDLNQPPETLNPLYFEQPLAPPLAA
KRAGQVVDLLPAWQAVQQLQSQFDWVLVEGVGSLGSPVTDELIVADIARDWRLPIVLVVPIRLGCVGQAVAHVALARQFG
LDVKGIVLNATGVLSTEEIQQWAPADMIQALTQVPVIGQVPHLSDPTNRAALAEVASGLDLEMLGSLSYATQDCQRNFQD
K
>Mature_240_residues
AQTLLISGSDTEIGKTIVTSALLAYWQIYRPNEKIAVCKPVQSGLGDREWYTEVFDLNQPPETLNPLYFEQPLAPPLAAK
RAGQVVDLLPAWQAVQQLQSQFDWVLVEGVGSLGSPVTDELIVADIARDWRLPIVLVVPIRLGCVGQAVAHVALARQFGL
DVKGIVLNATGVLSTEEIQQWAPADMIQALTQVPVIGQVPHLSDPTNRAALAEVASGLDLEMLGSLSYATQDCQRNFQDK

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=228, Percent_Identity=29.8245614035088, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 26221; Mature: 26090

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQTLLISGSDTEIGKTIVTSALLAYWQIYRPNEKIAVCKPVQSGLGDREWYTEVFDLNQ
CCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHCCCCHHHHHHHHCCCC
PPETLNPLYFEQPLAPPLAAKRAGQVVDLLPAWQAVQQLQSQFDWVLVEGVGSLGSPVTD
CCHHCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCHH
ELIVADIARDWRLPIVLVVPIRLGCVGQAVAHVALARQFGLDVKGIVLNATGVLSTEEIQ
HHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHH
QWAPADMIQALTQVPVIGQVPHLSDPTNRAALAEVASGLDLEMLGSLSYATQDCQRNFQD
HCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCC
K
C
>Mature Secondary Structure 
AQTLLISGSDTEIGKTIVTSALLAYWQIYRPNEKIAVCKPVQSGLGDREWYTEVFDLNQ
CCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHCCCCHHHHHHHHCCCC
PPETLNPLYFEQPLAPPLAAKRAGQVVDLLPAWQAVQQLQSQFDWVLVEGVGSLGSPVTD
CCHHCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCHH
ELIVADIARDWRLPIVLVVPIRLGCVGQAVAHVALARQFGLDVKGIVLNATGVLSTEEIQ
HHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHH
QWAPADMIQALTQVPVIGQVPHLSDPTNRAALAEVASGLDLEMLGSLSYATQDCQRNFQD
HCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA