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The map label for this gene is yoeB [H]

Identifier: 158335753

GI number: 158335753

Start: 2641553

End: 2641825

Strand: Direct

Name: yoeB [H]

Synonym: AM1_2604

Alternate gene names: 158335753

Gene position: 2641553-2641825 (Clockwise)

Preceding gene: 158335752

Following gene: 158335757

Centisome position: 40.62

GC content: 41.76

Gene sequence:

>273_bases
ATGAGATCTTTAGTCTTTGAAGGTAATACCTGGAGCGCCTATGAAAAGTTGAGAGAGAAAGACAAGAAACTGCATCGGAA
TCTTTGTAAGATCCTCAAAGAGATGCTGCGAGGAGATCCTAGCTCAGGACTCGGCAAGCCAGAACTTCTAAAACATAATC
TTTCTGGTTTGTGGTCTCGAAGGATATCGCAAAAAGATAGACTCGTCTATCGATTTGATGATAACTACATCTACATCTTC
GCCATCGGTGGTCATTATGACCAAATCACCTAG

Upstream 100 bases:

>100_bases
CTGCGTATATTACAAAGTAGTGACTTGATGCAGCAGATTTCTGAGTCTTTTGCCACTCATCTAAACCAGCAAGGCTACAC
ACCATCCACCGAGGAAATGG

Downstream 100 bases:

>100_bases
AGCTAGCACATTCCATAATCGGACTGCCATGTACGATAAAAAACACACTACCAATGGTCTTCTTGATATCGAGACACTCG
ATCAGCTATCCGTTTCACAT

Product: addiction module antitoxin

Products: NA

Alternate protein names: Putative endoribonuclease YoeB; Putative mRNA interferase Yoeb [H]

Number of amino acids: Translated: 90; Mature: 90

Protein sequence:

>90_residues
MRSLVFEGNTWSAYEKLREKDKKLHRNLCKILKEMLRGDPSSGLGKPELLKHNLSGLWSRRISQKDRLVYRFDDNYIYIF
AIGGHYDQIT

Sequences:

>Translated_90_residues
MRSLVFEGNTWSAYEKLREKDKKLHRNLCKILKEMLRGDPSSGLGKPELLKHNLSGLWSRRISQKDRLVYRFDDNYIYIF
AIGGHYDQIT
>Mature_90_residues
MRSLVFEGNTWSAYEKLREKDKKLHRNLCKILKEMLRGDPSSGLGKPELLKHNLSGLWSRRISQKDRLVYRFDDNYIYIF
AIGGHYDQIT

Specific function: Part of a toxin-antitoxin (TA) module. It has been proposed to be an mRNA interferase but also an inhibitor of translation initiation. Has an in vitro RNase activity and preferentially cleaves at the 3'-end of purine ribonucleotides. YefM binds to the pro

COG id: COG4115

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the YoeB family [H]

Homologues:

Organism=Escherichia coli, GI87082025, Length=83, Percent_Identity=42.1686746987952, Blast_Score=69, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009614 [H]

Pfam domain/function: PF06769 Plasmid_Txe [H]

EC number: NA

Molecular weight: Translated: 10659; Mature: 10659

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSLVFEGNTWSAYEKLREKDKKLHRNLCKILKEMLRGDPSSGLGKPELLKHNLSGLWSR
CCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
RISQKDRLVYRFDDNYIYIFAIGGHYDQIT
HCCCCCCEEEEECCCEEEEEEECCCCCCCC
>Mature Secondary Structure
MRSLVFEGNTWSAYEKLREKDKKLHRNLCKILKEMLRGDPSSGLGKPELLKHNLSGLWSR
CCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
RISQKDRLVYRFDDNYIYIFAIGGHYDQIT
HCCCCCCEEEEECCCEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]