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The map label for this gene is mdh [H]

Identifier: 158335747

GI number: 158335747

Start: 2638040

End: 2639107

Strand: Direct

Name: mdh [H]

Synonym: AM1_2598

Alternate gene names: 158335747

Gene position: 2638040-2639107 (Clockwise)

Preceding gene: 158335746

Following gene: 158335748

Centisome position: 40.56

GC content: 54.78

Gene sequence:

>1068_bases
ATGAACCCACTGATTCAGGTTTCTGCCGCTCAGCTTCGCGCCTTTCTCACCGCTGTTTTAGCGAACTATCCCCTGCAATC
CGAGGCTGCTACTGCGATCACCGATCACTTAGTCCAAGCCAATTTATGGGGCATGGATTCCCACGGGTTGCAGCAAATTA
TGGGGTATGACAAAAGTCTGCGGAGCGGTCGGATTAACCCTCAACCCAAGTTACACATCCAAACGGATCGCCCCACGATG
ATCCGGATCGAAGCCGATCGTGCGCCTGGACAGTATGCCGGTCAGATAGCCATGCAACAGGCGATTACCAAGGCTCAGGA
GATGGGCATGGCAGTGGTGGGGGTCACCAACAGCAACCATTTTGGCATGGCAGGCTACTATACACGGATGGCCGCCGCTG
CTGGGATGATCGGTTTTGCTACCAGCGACACTAATGTCGTGGATTTAGCCCCCTATGGTGGCAAAGAAGCCCGCCTTGGC
AATAACCCTTTTTCCTGGGGCATTCCCAACGGTGATATGCCCATCGTGTTGGATATGGCGGCGGGAACCGTGAGTGGCGG
CAAAATTAAGCATTTCGGCTATCAAGGACTGCCCATCCCACCAGAGTGGGGTTTAACGGCAGCAGGCGAGACCACCTCTG
AAGCGCAAGCGGTGGCGGTCAATCAAGCCGCTTCGCCCAAAGGAGCGGGGATGGCCCTGGTTGCGGATCTGCTCTGTGGC
CCGCTTTTGGGAACGGCAGCAGCTCTATTTAAAACCAAATCCAGGCATGATCGCATGAACGGTACGGGGCATTTTTTCTG
GGTGATGGATCTGGCAGTCTGGTCTGATCCAGAGGAATTTGCAGAGCGGGTGGGGGATGCGATCGCAACCCTAAAACAAA
CCCCACGCCTCGACCCCCAACAGCCCATCTATTTCCCCGGTGAGTTGGAAGTTGTAACAGAGCAGACGCGCATACACCAG
GGAATTCCTGTACCCTATGCTCTAATCCAGGATTTGGCCCGTCACTTCGGCCCTGACTTGGTAAATCAACACCTAACGCC
TGATCTGTCTATCTCGATTAACGCTTGA

Upstream 100 bases:

>100_bases
TTCCAGGCTGGCGGGTGCGCACCCAACGATGGGTCCAACCCCCTGAATCCCCCAAAATCCTCACCTACCAAACCGAAGAT
ACCTACCATCCCTACCCCCT

Downstream 100 bases:

>100_bases
ATCCATCCACCCCAACAAGCCAAGGCCGCTTAACAGCGGCAGGTTTTATCGGTCTCTACCTCCACGGCATTGTGGTCGCC
ATGCCCGGTGCGTTCCTCCA

Product: malate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MNPLIQVSAAQLRAFLTAVLANYPLQSEAATAITDHLVQANLWGMDSHGLQQIMGYDKSLRSGRINPQPKLHIQTDRPTM
IRIEADRAPGQYAGQIAMQQAITKAQEMGMAVVGVTNSNHFGMAGYYTRMAAAAGMIGFATSDTNVVDLAPYGGKEARLG
NNPFSWGIPNGDMPIVLDMAAGTVSGGKIKHFGYQGLPIPPEWGLTAAGETTSEAQAVAVNQAASPKGAGMALVADLLCG
PLLGTAAALFKTKSRHDRMNGTGHFFWVMDLAVWSDPEEFAERVGDAIATLKQTPRLDPQQPIYFPGELEVVTEQTRIHQ
GIPVPYALIQDLARHFGPDLVNQHLTPDLSISINA

Sequences:

>Translated_355_residues
MNPLIQVSAAQLRAFLTAVLANYPLQSEAATAITDHLVQANLWGMDSHGLQQIMGYDKSLRSGRINPQPKLHIQTDRPTM
IRIEADRAPGQYAGQIAMQQAITKAQEMGMAVVGVTNSNHFGMAGYYTRMAAAAGMIGFATSDTNVVDLAPYGGKEARLG
NNPFSWGIPNGDMPIVLDMAAGTVSGGKIKHFGYQGLPIPPEWGLTAAGETTSEAQAVAVNQAASPKGAGMALVADLLCG
PLLGTAAALFKTKSRHDRMNGTGHFFWVMDLAVWSDPEEFAERVGDAIATLKQTPRLDPQQPIYFPGELEVVTEQTRIHQ
GIPVPYALIQDLARHFGPDLVNQHLTPDLSISINA
>Mature_355_residues
MNPLIQVSAAQLRAFLTAVLANYPLQSEAATAITDHLVQANLWGMDSHGLQQIMGYDKSLRSGRINPQPKLHIQTDRPTM
IRIEADRAPGQYAGQIAMQQAITKAQEMGMAVVGVTNSNHFGMAGYYTRMAAAAGMIGFATSDTNVVDLAPYGGKEARLG
NNPFSWGIPNGDMPIVLDMAAGTVSGGKIKHFGYQGLPIPPEWGLTAAGETTSEAQAVAVNQAASPKGAGMALVADLLCG
PLLGTAAALFKTKSRHDRMNGTGHFFWVMDLAVWSDPEEFAERVGDAIATLKQTPRLDPQQPIYFPGELEVVTEQTRIHQ
GIPVPYALIQDLARHFGPDLVNQHLTPDLSISINA

Specific function: Unknown

COG id: COG2055

COG function: function code C; Malate/L-lactate dehydrogenases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LDH2/MDH2 oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787020, Length=347, Percent_Identity=29.971181556196, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1786727, Length=333, Percent_Identity=27.9279279279279, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1790000, Length=336, Percent_Identity=26.4880952380952, Blast_Score=103, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17507179, Length=329, Percent_Identity=27.9635258358663, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17536633, Length=362, Percent_Identity=26.2430939226519, Blast_Score=111, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24667904, Length=319, Percent_Identity=29.153605015674, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI45553211, Length=319, Percent_Identity=29.153605015674, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24667912, Length=319, Percent_Identity=29.153605015674, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24667908, Length=321, Percent_Identity=29.9065420560748, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24658010, Length=308, Percent_Identity=26.2987012987013, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24648360, Length=349, Percent_Identity=25.5014326647564, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003767 [H]

Pfam domain/function: PF02615 Ldh_2 [H]

EC number: =1.1.1.37 [H]

Molecular weight: Translated: 38067; Mature: 38067

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPLIQVSAAQLRAFLTAVLANYPLQSEAATAITDHLVQANLWGMDSHGLQQIMGYDKSL
CCCCEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHH
RSGRINPQPKLHIQTDRPTMIRIEADRAPGQYAGQIAMQQAITKAQEMGMAVVGVTNSNH
HCCCCCCCCCEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCC
FGMAGYYTRMAAAAGMIGFATSDTNVVDLAPYGGKEARLGNNPFSWGIPNGDMPIVLDMA
CCCHHHHHHHHHHHHHEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEC
AGTVSGGKIKHFGYQGLPIPPEWGLTAAGETTSEAQAVAVNQAASPKGAGMALVADLLCG
CCCCCCCEEEECCCCCCCCCCCCCCEECCCCCCCHHEEEECCCCCCCCCCHHHHHHHHHH
PLLGTAAALFKTKSRHDRMNGTGHFFWVMDLAVWSDPEEFAERVGDAIATLKQTPRLDPQ
HHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEHHCCCHHHHHHHHHHHHHHHHHCCCCCCC
QPIYFPGELEVVTEQTRIHQGIPVPYALIQDLARHFGPDLVNQHLTPDLSISINA
CCEECCCCEEEEEHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHCCCCCCEEEECC
>Mature Secondary Structure
MNPLIQVSAAQLRAFLTAVLANYPLQSEAATAITDHLVQANLWGMDSHGLQQIMGYDKSL
CCCCEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHH
RSGRINPQPKLHIQTDRPTMIRIEADRAPGQYAGQIAMQQAITKAQEMGMAVVGVTNSNH
HCCCCCCCCCEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCC
FGMAGYYTRMAAAAGMIGFATSDTNVVDLAPYGGKEARLGNNPFSWGIPNGDMPIVLDMA
CCCHHHHHHHHHHHHHEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEC
AGTVSGGKIKHFGYQGLPIPPEWGLTAAGETTSEAQAVAVNQAASPKGAGMALVADLLCG
CCCCCCCEEEECCCCCCCCCCCCCCEECCCCCCCHHEEEECCCCCCCCCCHHHHHHHHHH
PLLGTAAALFKTKSRHDRMNGTGHFFWVMDLAVWSDPEEFAERVGDAIATLKQTPRLDPQ
HHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEHHCCCHHHHHHHHHHHHHHHHHCCCCCCC
QPIYFPGELEVVTEQTRIHQGIPVPYALIQDLARHFGPDLVNQHLTPDLSISINA
CCEECCCCEEEEEHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]