Click here to switch to the map view.

The map label for this gene is lepB [H]

Identifier: 158335724

GI number: 158335724

Start: 2613597

End: 2614373

Strand: Direct

Name: lepB [H]

Synonym: AM1_2574

Alternate gene names: 158335724

Gene position: 2613597-2614373 (Clockwise)

Preceding gene: 158335723

Following gene: 158335725

Centisome position: 40.19

GC content: 42.6

Gene sequence:

>777_bases
ATGGGGAAATGGATTTTAGGCTCAATTCTAATTGTGGCTGAAATTCTAACTTGGATTTATGCTCCGGCGCTAGTCTTCCT
GGGGCTGTGGTTTGTTTTACCCTTTGTCGCTAACCATGCTTATCAAGCTGCCTCAGATCAACGAAAAAACAGCAAAAATA
TCATATTAAAATTATTTCTGCTGCTGTTTATTGCCCCGATCGGGCTATCTATCACGTTGGGCCTCGCTATTCGCTCATTG
ATTGTAGAAGCTCGATATATTCCATCTGGAGGAATGGAGCCAACTCTACAGATTAATGATCGTATCGTTATAGATAAAGT
CAGTTATGTATTTCGAACCCCAAAACGAGGAGAAATTATTCTTTTTGAACCCACACAGGCATTAAAACGAGGTGGCTTTG
AGAATGCTTTTTTAAAGCGGATTATTGGCCTCCCTGGTGATAAGGTCGAGATTAAACAGAATGTTATATGGATTAATAAT
CAACCCTTGCAAGAACCCTACACAATGTCGGGCACCACTGAGAGTCCAAGCCCCGACATATGCCGTTCCAATTATGTAAC
GATGGACGTCGAGAGCAAGCCCATTGATCCGCCTATTCCCATCTATTTATCCCAACCTCAAACGATCCCTCCCGGTCATT
ATTTAGTATTAGGAGACCACCGAGAACTGAGTCTCGATAGTCGGTGCTGGGGGCTGGTTAAACGGAGTGAAATTATTGGC
CAAGCAACCAAAAGATTTTTCCCGTTTAACCGTATGGGTCGTTTAGATAAAAAGTAG

Upstream 100 bases:

>100_bases
CACCAACGATTCAGCATTTGAAAATCATCGAACAACGCTCAAAGATCCCTGGCTTGCCGTGTTCCTAAGTCGTTTTATAT
TAGGAGCTGGCCATCTTTAT

Downstream 100 bases:

>100_bases
GTGCTATCGATAGGTTTTGACGATTTTCTGAAGCAGATTCTCATCATCTCCATTGTCATACGCTTCCAGATCTTTATTGC
CAGACATCTCGATCTGGAAG

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MGKWILGSILIVAEILTWIYAPALVFLGLWFVLPFVANHAYQAASDQRKNSKNIILKLFLLLFIAPIGLSITLGLAIRSL
IVEARYIPSGGMEPTLQINDRIVIDKVSYVFRTPKRGEIILFEPTQALKRGGFENAFLKRIIGLPGDKVEIKQNVIWINN
QPLQEPYTMSGTTESPSPDICRSNYVTMDVESKPIDPPIPIYLSQPQTIPPGHYLVLGDHRELSLDSRCWGLVKRSEIIG
QATKRFFPFNRMGRLDKK

Sequences:

>Translated_258_residues
MGKWILGSILIVAEILTWIYAPALVFLGLWFVLPFVANHAYQAASDQRKNSKNIILKLFLLLFIAPIGLSITLGLAIRSL
IVEARYIPSGGMEPTLQINDRIVIDKVSYVFRTPKRGEIILFEPTQALKRGGFENAFLKRIIGLPGDKVEIKQNVIWINN
QPLQEPYTMSGTTESPSPDICRSNYVTMDVESKPIDPPIPIYLSQPQTIPPGHYLVLGDHRELSLDSRCWGLVKRSEIIG
QATKRFFPFNRMGRLDKK
>Mature_257_residues
GKWILGSILIVAEILTWIYAPALVFLGLWFVLPFVANHAYQAASDQRKNSKNIILKLFLLLFIAPIGLSITLGLAIRSLI
VEARYIPSGGMEPTLQINDRIVIDKVSYVFRTPKRGEIILFEPTQALKRGGFENAFLKRIIGLPGDKVEIKQNVIWINNQ
PLQEPYTMSGTTESPSPDICRSNYVTMDVESKPIDPPIPIYLSQPQTIPPGHYLVLGDHRELSLDSRCWGLVKRSEIIGQ
ATKRFFPFNRMGRLDKK

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:
GO:0006508: Signal peptidase I
GO:0008236: Signal peptidase I
GO:0016020: Signal peptidase I
GO:0016021: Signal peptidase I

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 29146; Mature: 29014

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKWILGSILIVAEILTWIYAPALVFLGLWFVLPFVANHAYQAASDQRKNSKNIILKLFL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LLFIAPIGLSITLGLAIRSLIVEARYIPSGGMEPTLQINDRIVIDKVSYVFRTPKRGEII
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCEEEEEEHHHHHCCCCCCCEE
LFEPTQALKRGGFENAFLKRIIGLPGDKVEIKQNVIWINNQPLQEPYTMSGTTESPSPDI
EECCHHHHHCCCCHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCC
CRSNYVTMDVESKPIDPPIPIYLSQPQTIPPGHYLVLGDHRELSLDSRCWGLVKRSEIIG
CCCCCEEEEECCCCCCCCCCEEECCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHH
QATKRFFPFNRMGRLDKK
HHHHHHCCCHHCCCCCCC
>Mature Secondary Structure 
GKWILGSILIVAEILTWIYAPALVFLGLWFVLPFVANHAYQAASDQRKNSKNIILKLFL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LLFIAPIGLSITLGLAIRSLIVEARYIPSGGMEPTLQINDRIVIDKVSYVFRTPKRGEII
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCEEEEEEHHHHHCCCCCCCEE
LFEPTQALKRGGFENAFLKRIIGLPGDKVEIKQNVIWINNQPLQEPYTMSGTTESPSPDI
EECCHHHHHCCCCHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCC
CRSNYVTMDVESKPIDPPIPIYLSQPQTIPPGHYLVLGDHRELSLDSRCWGLVKRSEIIG
CCCCCEEEEECCCCCCCCCCEEECCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHH
QATKRFFPFNRMGRLDKK
HHHHHHCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7865790 [H]