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The map label for this gene is yccK [H]

Identifier: 158335682

GI number: 158335682

Start: 2565842

End: 2566807

Strand: Reverse

Name: yccK [H]

Synonym: AM1_2531

Alternate gene names: 158335682

Gene position: 2566807-2565842 (Counterclockwise)

Preceding gene: 158335683

Following gene: 158335680

Centisome position: 39.47

GC content: 46.38

Gene sequence:

>966_bases
ATGTTGACCATTAATTCAACGCCAATCAAGCAAATCGGCTATGGTGCCATGGTATTGGAAGGTTACTACGGTGCCAGCGA
AGATCAAACGGCAGTAGAAACCCTGACCTATGCCATTGAGCAGAATATGATGATCGATACGGCTGATGCCTATGGTGCAG
GACATAACGAAAGCTTACTTAAACAAGCCATACAGCAATCCACCCAAACGCCTTTTGTGGCAACCAAGTTCGGCATTGTA
TTTGAAGAAGATCAAACGGGCCATCAAATAGACACCGGTTGGGGATTTCCCCTCACCATCAACGGCACTCGGTCCTACGT
TAAACGTGCGATTGACAACAGCCTTGAGCGCCTGGGTGTCAATCAAATTGATTTACTGTATGCACACTACCTTGATCCCA
GTACCTCCCTGGAAGAAACGGTCTCTGCCATGGCAGAAGCTGTTCAAGCGGGCAAGGTGAAAGCGATTGGATTGTCTAAT
GTAACCGCTGAGGAAATTATTCAAGCAAATCAGGTCCATCCCATTTCAGCGGTTCAATACGAATATTCCTTATTTAGACG
TGAAGCGGAGACTGATATTTTGCCAGCCATTAACAGTATCAGCGCATCCCTTGTTTGTTGGTCCCCCCTTGGCGCTGGAT
TCCTAACAGGTACTGTTAAGCAGTTAGATGACGGTGATTTCCGCACTAATAATCCTAAAATGCAAGGCGAGAATCTCAGC
AAAAACCTTCAGCGTCTTGAGGACATCAAAAAGATTGCTCTTGATTTGAACATTACGCCTGCACAGCTTGCCCTGGCTTG
GTTAATTGCCCAAGGTGACAATATCATTCCGATTCCAGGGAGTCGCAAAAAATCCCGTATCGATGAAAATCTTGCGGCTC
TTGGTATTCAGTTAAGTGCAGAAACGTTGCGAAACCTGGATGAGATCGCACCCATCGGGGCATTTCAAGGGGCAACTTTG
GTTTAG

Upstream 100 bases:

>100_bases
GGCTGCGATTCGTGCCTTTTTGGGGTTTAGTAACCTGGCTAATTATTTAAGTGGCAGAGCCATTCAATCGTAACTATAAG
CATCTCCCTAGGAGTAAATT

Downstream 100 bases:

>100_bases
CCCTGGGGGATTAAACCCTCAAGAATAGTGAGTACTTCATCCATTCCTGCATTGTGATCGACGAACGAAAACATATGGCG
GAAGCGGATTGTGCCGTCTA

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MLTINSTPIKQIGYGAMVLEGYYGASEDQTAVETLTYAIEQNMMIDTADAYGAGHNESLLKQAIQQSTQTPFVATKFGIV
FEEDQTGHQIDTGWGFPLTINGTRSYVKRAIDNSLERLGVNQIDLLYAHYLDPSTSLEETVSAMAEAVQAGKVKAIGLSN
VTAEEIIQANQVHPISAVQYEYSLFRREAETDILPAINSISASLVCWSPLGAGFLTGTVKQLDDGDFRTNNPKMQGENLS
KNLQRLEDIKKIALDLNITPAQLALAWLIAQGDNIIPIPGSRKKSRIDENLAALGIQLSAETLRNLDEIAPIGAFQGATL
V

Sequences:

>Translated_321_residues
MLTINSTPIKQIGYGAMVLEGYYGASEDQTAVETLTYAIEQNMMIDTADAYGAGHNESLLKQAIQQSTQTPFVATKFGIV
FEEDQTGHQIDTGWGFPLTINGTRSYVKRAIDNSLERLGVNQIDLLYAHYLDPSTSLEETVSAMAEAVQAGKVKAIGLSN
VTAEEIIQANQVHPISAVQYEYSLFRREAETDILPAINSISASLVCWSPLGAGFLTGTVKQLDDGDFRTNNPKMQGENLS
KNLQRLEDIKKIALDLNITPAQLALAWLIAQGDNIIPIPGSRKKSRIDENLAALGIQLSAETLRNLDEIAPIGAFQGATL
V
>Mature_321_residues
MLTINSTPIKQIGYGAMVLEGYYGASEDQTAVETLTYAIEQNMMIDTADAYGAGHNESLLKQAIQQSTQTPFVATKFGIV
FEEDQTGHQIDTGWGFPLTINGTRSYVKRAIDNSLERLGVNQIDLLYAHYLDPSTSLEETVSAMAEAVQAGKVKAIGLSN
VTAEEIIQANQVHPISAVQYEYSLFRREAETDILPAINSISASLVCWSPLGAGFLTGTVKQLDDGDFRTNNPKMQGENLS
KNLQRLEDIKKIALDLNITPAQLALAWLIAQGDNIIPIPGSRKKSRIDENLAALGIQLSAETLRNLDEIAPIGAFQGATL
V

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=324, Percent_Identity=26.5432098765432, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI4504825, Length=324, Percent_Identity=26.5432098765432, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI27436971, Length=301, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI27436962, Length=322, Percent_Identity=26.3975155279503, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI27436964, Length=322, Percent_Identity=26.3975155279503, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI27436966, Length=322, Percent_Identity=26.3975155279503, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI41152114, Length=142, Percent_Identity=31.6901408450704, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1788070, Length=312, Percent_Identity=30.4487179487179, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI87081735, Length=276, Percent_Identity=31.1594202898551, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1787674, Length=319, Percent_Identity=28.8401253918495, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789375, Length=258, Percent_Identity=27.5193798449612, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1788081, Length=291, Percent_Identity=26.1168384879725, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789199, Length=243, Percent_Identity=25.5144032921811, Blast_Score=65, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=336, Percent_Identity=27.9761904761905, Blast_Score=105, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6323998, Length=312, Percent_Identity=25.9615384615385, Blast_Score=90, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6322615, Length=260, Percent_Identity=26.5384615384615, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6319958, Length=288, Percent_Identity=25.3472222222222, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6325384, Length=218, Percent_Identity=30.2752293577982, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6319951, Length=215, Percent_Identity=26.046511627907, Blast_Score=76, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24640980, Length=323, Percent_Identity=24.4582043343653, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45549126, Length=323, Percent_Identity=24.4582043343653, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34873; Mature: 34873

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTINSTPIKQIGYGAMVLEGYYGASEDQTAVETLTYAIEQNMMIDTADAYGAGHNESLL
CEECCCCCHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEECHHHCCCCCCHHHH
KQAIQQSTQTPFVATKFGIVFEEDQTGHQIDTGWGFPLTINGTRSYVKRAIDNSLERLGV
HHHHHHHCCCCEEEEEECEEEECCCCCCEEECCCCCEEEECCHHHHHHHHHHHHHHHCCC
NQIDLLYAHYLDPSTSLEETVSAMAEAVQAGKVKAIGLSNVTAEEIIQANQVHPISAVQY
CHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHCCCCCCHHHHH
EYSLFRREAETDILPAINSISASLVCWSPLGAGFLTGTVKQLDDGDFRTNNPKMQGENLS
HHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHH
KNLQRLEDIKKIALDLNITPAQLALAWLIAQGDNIIPIPGSRKKSRIDENLAALGIQLSA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHEEEECH
ETLRNLDEIAPIGAFQGATLV
HHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MLTINSTPIKQIGYGAMVLEGYYGASEDQTAVETLTYAIEQNMMIDTADAYGAGHNESLL
CEECCCCCHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEECHHHCCCCCCHHHH
KQAIQQSTQTPFVATKFGIVFEEDQTGHQIDTGWGFPLTINGTRSYVKRAIDNSLERLGV
HHHHHHHCCCCEEEEEECEEEECCCCCCEEECCCCCEEEECCHHHHHHHHHHHHHHHCCC
NQIDLLYAHYLDPSTSLEETVSAMAEAVQAGKVKAIGLSNVTAEEIIQANQVHPISAVQY
CHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHCCCCCCHHHHH
EYSLFRREAETDILPAINSISASLVCWSPLGAGFLTGTVKQLDDGDFRTNNPKMQGENLS
HHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHH
KNLQRLEDIKKIALDLNITPAQLALAWLIAQGDNIIPIPGSRKKSRIDENLAALGIQLSA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHEEEECH
ETLRNLDEIAPIGAFQGATLV
HHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]