Click here to switch to the map view.

The map label for this gene is gluP [H]

Identifier: 158335670

GI number: 158335670

Start: 2557978

End: 2558697

Strand: Reverse

Name: gluP [H]

Synonym: AM1_2520

Alternate gene names: 158335670

Gene position: 2558697-2557978 (Counterclockwise)

Preceding gene: 158335671

Following gene: 158335669

Centisome position: 39.34

GC content: 50.97

Gene sequence:

>720_bases
GTGGTTCCTCTTCGCGATGAAAATCCAACTCAAATCACGCCCTATGTGACCTATGGCCTGATTGTTCTCAATGTATTGAT
CTTTGGCTATGAGTTGAGCTTGTCTCCGGGACAGCTCAGCCTCTTTATGCAGCATTGGGCGGTGGTTCCCATCGAACTGA
CTGCGAGTTTTGGCGGCTTTTCTGCGGTGGATGCCGGAGAGTGGGGCACCTTGATTACCTCCCAATTTCTCCATGGCGGT
TTTTTGCATGTGGCGGGCAATATGCTCTACCTATGGATTTTTGGCAATAACGTGGAAGAGCAGCTGGGACGTATACGGTT
TCTGCTCTTTTATTTAGCCTGCGGGGCTTTGGCAGTTCTAACCCAATGGTTTTTCAACCCCCTGTCGGTGGTGCCATCCT
TAGGAGCCAGCGGTGCGATCGCAGGGGTGATGGGGGCCTATATCTTTCGCTTCCCCCAAGTCAGAATTCTAACCCTAGTC
CCCTTGGGCATCTATCTGACTACCTTTAGAATTCCCGCGATTCTCTACCTGGGATTTTGGTTTTTGCAGCAAGCTTTTTA
CGGTGTTGCCAGTTTAGACGCTCCCGTCACTGTCGGTATGGAAGCGGGTGGAATTGCCTATTGGGCCCATGCCGGTGGAT
TTGTATTTGGCGCAATTCTGGGGCCGCTTCTGGGGTTATTTAGCAAAGCAGATAGCGCTGTGCTTTCTGCTGAAGATTAG

Upstream 100 bases:

>100_bases
AACGCTGCGCATTGAACCTGCTAAGACTCAGGGATAACACACCCGTTCACGGGATAAATAAACTAAGCTGCATAGTAGTC
CCCCCAGCGAGGTTGTACAA

Downstream 100 bases:

>100_bases
GCCCTCCATGAAGTTGATTGCGGATCCTGCCGTCGCCGTCAAAATTGCCAAAATGCAGGAGCGGGTATGTTGGCAGCATC
CTGTTCTACAGGCTAGAGGG

Product: rhomboid family protein

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MVPLRDENPTQITPYVTYGLIVLNVLIFGYELSLSPGQLSLFMQHWAVVPIELTASFGGFSAVDAGEWGTLITSQFLHGG
FLHVAGNMLYLWIFGNNVEEQLGRIRFLLFYLACGALAVLTQWFFNPLSVVPSLGASGAIAGVMGAYIFRFPQVRILTLV
PLGIYLTTFRIPAILYLGFWFLQQAFYGVASLDAPVTVGMEAGGIAYWAHAGGFVFGAILGPLLGLFSKADSAVLSAED

Sequences:

>Translated_239_residues
MVPLRDENPTQITPYVTYGLIVLNVLIFGYELSLSPGQLSLFMQHWAVVPIELTASFGGFSAVDAGEWGTLITSQFLHGG
FLHVAGNMLYLWIFGNNVEEQLGRIRFLLFYLACGALAVLTQWFFNPLSVVPSLGASGAIAGVMGAYIFRFPQVRILTLV
PLGIYLTTFRIPAILYLGFWFLQQAFYGVASLDAPVTVGMEAGGIAYWAHAGGFVFGAILGPLLGLFSKADSAVLSAED
>Mature_239_residues
MVPLRDENPTQITPYVTYGLIVLNVLIFGYELSLSPGQLSLFMQHWAVVPIELTASFGGFSAVDAGEWGTLITSQFLHGG
FLHVAGNMLYLWIFGNNVEEQLGRIRFLLFYLACGALAVLTQWFFNPLSVVPSLGASGAIAGVMGAYIFRFPQVRILTLV
PLGIYLTTFRIPAILYLGFWFLQQAFYGVASLDAPVTVGMEAGGIAYWAHAGGFVFGAILGPLLGLFSKADSAVLSAED

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis. Important for normal cell division and sporulation. May act as a glucose exporter [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 TPR repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002610
- InterPro:   IPR022764
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF01694 Rhomboid; PF00515 TPR_1 [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 25884; Mature: 25884

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPLRDENPTQITPYVTYGLIVLNVLIFGYELSLSPGQLSLFMQHWAVVPIELTASFGGF
CCCCCCCCCCEECHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHEEEEEEEEECCCCC
SAVDAGEWGTLITSQFLHGGFLHVAGNMLYLWIFGNNVEEQLGRIRFLLFYLACGALAVL
CCCCCCCCHHHHHHHHHHCCHHEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
TQWFFNPLSVVPSLGASGAIAGVMGAYIFRFPQVRILTLVPLGIYLTTFRIPAILYLGFW
HHHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHH
FLQQAFYGVASLDAPVTVGMEAGGIAYWAHAGGFVFGAILGPLLGLFSKADSAVLSAED
HHHHHHHHHHCCCCCEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEECCC
>Mature Secondary Structure
MVPLRDENPTQITPYVTYGLIVLNVLIFGYELSLSPGQLSLFMQHWAVVPIELTASFGGF
CCCCCCCCCCEECHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHEEEEEEEEECCCCC
SAVDAGEWGTLITSQFLHGGFLHVAGNMLYLWIFGNNVEEQLGRIRFLLFYLACGALAVL
CCCCCCCCHHHHHHHHHHCCHHEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
TQWFFNPLSVVPSLGASGAIAGVMGAYIFRFPQVRILTLVPLGIYLTTFRIPAILYLGFW
HHHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHH
FLQQAFYGVASLDAPVTVGMEAGGIAYWAHAGGFVFGAILGPLLGLFSKADSAVLSAED
HHHHHHHHHHCCCCCEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]