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The map label for this gene is trx [H]

Identifier: 158335645

GI number: 158335645

Start: 2519258

End: 2519608

Strand: Direct

Name: trx [H]

Synonym: AM1_2495

Alternate gene names: 158335645

Gene position: 2519258-2519608 (Clockwise)

Preceding gene: 158335644

Following gene: 158335646

Centisome position: 38.74

GC content: 49.29

Gene sequence:

>351_bases
ATGCTGTCTACGACTAGTACCCAGACTTTCAACCCAGACGTTTTACAATCTGAGACGCCCGTTCTAGTTAGCTTTTGGGC
GCCTTGGTGTGGAGTCTGTCGTTGGGTGGAGCCGATGCTGATCCAGGTACAAGCAGATTACGGTTCGGCACTCAAAATTG
TCACCATCAATGCCGACGAAAATTTTCTCATTGCCAGCCAATATCGGCTCACGAATATTCCGAGTTTGTTGCTATTCCAG
CAGGGCCGTCTGGTTCACCGAATTGACCAGTTTTGCGATCGCACCGAAGCATTGAACTTACTAGAGAAAGCCCTCGGCAA
GATTGTTCCATCCCTAATGTCTGCCGGGTAA

Upstream 100 bases:

>100_bases
ATTTTGGATTGCCCATCCCTTAATGATGCGTGCAGCATTCAACGTTCGCTGGTAGCATGATCCCAGCTTATAAAATCTCT
TGTTTAAAACACCGTTGAGC

Downstream 100 bases:

>100_bases
CCTAACTTTACATACCTTAGTGCTCACAACCAAAATTTTCCAAGATATCCCAAATAGTCTTTGGGACTCATATTCGATGG
GTTAATCTTAAGATTTCTCA

Product: thioredoxin

Products: NA

Alternate protein names: Trx-1; Thioredoxin-M [H]

Number of amino acids: Translated: 116; Mature: 116

Protein sequence:

>116_residues
MLSTTSTQTFNPDVLQSETPVLVSFWAPWCGVCRWVEPMLIQVQADYGSALKIVTINADENFLIASQYRLTNIPSLLLFQ
QGRLVHRIDQFCDRTEALNLLEKALGKIVPSLMSAG

Sequences:

>Translated_116_residues
MLSTTSTQTFNPDVLQSETPVLVSFWAPWCGVCRWVEPMLIQVQADYGSALKIVTINADENFLIASQYRLTNIPSLLLFQ
QGRLVHRIDQFCDRTEALNLLEKALGKIVPSLMSAG
>Mature_116_residues
MLSTTSTQTFNPDVLQSETPVLVSFWAPWCGVCRWVEPMLIQVQADYGSALKIVTINADENFLIASQYRLTNIPSLLLFQ
QGRLVHRIDQFCDRTEALNLLEKALGKIVPSLMSAG

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI87082331, Length=80, Percent_Identity=36.25, Blast_Score=75, Evalue=1e-15,
Organism=Escherichia coli, GI1788936, Length=72, Percent_Identity=30.5555555555556, Blast_Score=63, Evalue=6e-12,

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: NA

Molecular weight: Translated: 12985; Mature: 12985

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSTTSTQTFNPDVLQSETPVLVSFWAPWCGVCRWVEPMLIQVQADYGSALKIVTINADE
CCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHCCEEEEEECCCCCEEEEEEEECCC
NFLIASQYRLTNIPSLLLFQQGRLVHRIDQFCDRTEALNLLEKALGKIVPSLMSAG
CEEEECCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLSTTSTQTFNPDVLQSETPVLVSFWAPWCGVCRWVEPMLIQVQADYGSALKIVTINADE
CCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHCCEEEEEECCCCCEEEEEEEECCC
NFLIASQYRLTNIPSLLLFQQGRLVHRIDQFCDRTEALNLLEKALGKIVPSLMSAG
CEEEECCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2492995 [H]