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The map label for this gene is emrA [C]

Identifier: 158335629

GI number: 158335629

Start: 2502816

End: 2504300

Strand: Direct

Name: emrA [C]

Synonym: AM1_2479

Alternate gene names: 158335629

Gene position: 2502816-2504300 (Clockwise)

Preceding gene: 158335628

Following gene: 158335630

Centisome position: 38.48

GC content: 51.25

Gene sequence:

>1485_bases
ATGAAGACGGATGAACGTACGCCAAAGGATACAGGAGATTTGGCTAATACTGATACTCCTTCTCAATTGGAACTAGATAT
TCAAGTCCCTGGAGACAAGCAGCCCCCCCACTCCAGACCTTCAGTATTTAGTAAAAAATCTCCCTGGCCCATTGCCATTC
TCGTCATGTTGGTGATTGCAGGGTTGTTCGGATGGCGACTCTACAACAACAGTCAGTCTCCGGCCGTATCGGAACCTGAA
ACCACGTCTACAGCCAAATTACCGGTGCGGGCAGTGCGGGCTCAACTCTCACCGATTCGCCGTTGGGTCACCAGCCCGGA
TGGCGATGTGAGAGCAGAACGATACAAACAACTGATTTTTGAATCCAGTGGAGAAGTCACCCAACTCGCCAAAATCAATG
GCCGCTTCCTGCGAGAAGGCGATCGCGTGGGTAAAGGTCAATTACTCGCAACCCTGGATGATCGCAAATATCAATCCGAT
ATTCGAGCCGCTGCCGCCGATCGCGAAGTTGCCAAACGTACAGAAGAGCAGGCGGTGGCCAGCTTACGTCAGACAGAAGC
CAATCTCAGGCAAGCCAAAGCTGACCTAGAACTCGCAAAAATAGAAGCCAAACGACGACAAACCTTGTACAAACAGGGAG
TGATTCCAGCGACGGAACGGGATACCTACAATAACCGCGTTATTCAGGCCCAAGTTGGGGTCAAGGTAGCCCAAGAAAAT
GTCAAAACGGCCCAAGATCAAATTGCCGTATCCAAGGCAGGGGTGGTCTCCAACCAAGCTCGATTATTAAACACAGTGAT
TGCCAGGGAAGATACGCAGCTCGTGTCTCCCATCAATGGCATTGTCGCCTATATGAATATTCGGGAAGGAGAATATTGGA
GTCCTTCCAGAGTACAGTCCGCCACCAGTTATCAAGCTGCTATCGAATCCGTCCCTATTGTGGTGGTTGACCCCAATAGT
TTTGAGGTTGCCTTTGAACTTCCCGCCTCAGAAGGGAGTTTGCTGCGCCCCAATCAACCCGCCTATGTTGCCTTAGATGA
CGATATTAGCCAAGCCTTTGTCCAAGGGCTCAATCAAAGCAATCTCGTTAGTGTGTCTAAAGCTCGAGGCAAGGTGTTTT
CCGTCACGCCAGCGGTCACTCCTGGGGGCAGAGCCGTCCAAGTGAGGGTTCGGATCACAGAAGGGCGAGAGAACTTACGC
CTAGGAGCCCGTGTGCAAACCTGGATTGCTGCTCAATCCAGAAGCCAAGCCATTACGTTGCCCTTTGGGTCCGTGATCAC
CCGCGATCGCAAATCCTATGTGTTTGTTGTCAATGAGGAGACGGGCCGAGTGGAGCAGCGTCCTGTGGTTTTAGATATTG
AAGGGTTAGATCGGATCTCGATTGCTCAGGGACTACAGCCCGGTGAATTGGTGGTCACCGAAGGCAGTAATCGACTGGTG
AATGATTCTCCCGTCGATGTTGTCGATATTGAAGATCCGGCCTAA

Upstream 100 bases:

>100_bases
AATGCTATAGAAATCCCGTAAAGTAATAGCTATAAGCTTTATCACATCAGCCTTATGGGTTCAACCAGCGGCATAATCCT
ATCAACATGGAACGAAACAC

Downstream 100 bases:

>100_bases
GTCAGCAGATTGCATTACCGCACTACACCGCAAGGATAAACCCCATGCAAACAGAGGATCGGCCAACTACCCTGGACGTT
CGGGATGCCCCCGTGCATGG

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: RND Family Efflux Transporter MFP Subunit; Membrane-Fusion Protein; Multidrug Efflux System Subunit MdtA; RND Efflux Membrane Fusion Protein; Cation/Multidrug Efflux System Mebrane-Fusion Component; Secretion Protein HlyD; Multidrug Efflux System Inner Membrane Protein; Acriflavin Resistance Protein A; Multidrug Efflux Transporter; Auxiliary Transport Protein MFP Family; Hlyd Family Secretion Protein; Multidrug Efflux System Subunit A; Efflux System

Number of amino acids: Translated: 494; Mature: 494

Protein sequence:

>494_residues
MKTDERTPKDTGDLANTDTPSQLELDIQVPGDKQPPHSRPSVFSKKSPWPIAILVMLVIAGLFGWRLYNNSQSPAVSEPE
TTSTAKLPVRAVRAQLSPIRRWVTSPDGDVRAERYKQLIFESSGEVTQLAKINGRFLREGDRVGKGQLLATLDDRKYQSD
IRAAAADREVAKRTEEQAVASLRQTEANLRQAKADLELAKIEAKRRQTLYKQGVIPATERDTYNNRVIQAQVGVKVAQEN
VKTAQDQIAVSKAGVVSNQARLLNTVIAREDTQLVSPINGIVAYMNIREGEYWSPSRVQSATSYQAAIESVPIVVVDPNS
FEVAFELPASEGSLLRPNQPAYVALDDDISQAFVQGLNQSNLVSVSKARGKVFSVTPAVTPGGRAVQVRVRITEGRENLR
LGARVQTWIAAQSRSQAITLPFGSVITRDRKSYVFVVNEETGRVEQRPVVLDIEGLDRISIAQGLQPGELVVTEGSNRLV
NDSPVDVVDIEDPA

Sequences:

>Translated_494_residues
MKTDERTPKDTGDLANTDTPSQLELDIQVPGDKQPPHSRPSVFSKKSPWPIAILVMLVIAGLFGWRLYNNSQSPAVSEPE
TTSTAKLPVRAVRAQLSPIRRWVTSPDGDVRAERYKQLIFESSGEVTQLAKINGRFLREGDRVGKGQLLATLDDRKYQSD
IRAAAADREVAKRTEEQAVASLRQTEANLRQAKADLELAKIEAKRRQTLYKQGVIPATERDTYNNRVIQAQVGVKVAQEN
VKTAQDQIAVSKAGVVSNQARLLNTVIAREDTQLVSPINGIVAYMNIREGEYWSPSRVQSATSYQAAIESVPIVVVDPNS
FEVAFELPASEGSLLRPNQPAYVALDDDISQAFVQGLNQSNLVSVSKARGKVFSVTPAVTPGGRAVQVRVRITEGRENLR
LGARVQTWIAAQSRSQAITLPFGSVITRDRKSYVFVVNEETGRVEQRPVVLDIEGLDRISIAQGLQPGELVVTEGSNRLV
NDSPVDVVDIEDPA
>Mature_494_residues
MKTDERTPKDTGDLANTDTPSQLELDIQVPGDKQPPHSRPSVFSKKSPWPIAILVMLVIAGLFGWRLYNNSQSPAVSEPE
TTSTAKLPVRAVRAQLSPIRRWVTSPDGDVRAERYKQLIFESSGEVTQLAKINGRFLREGDRVGKGQLLATLDDRKYQSD
IRAAAADREVAKRTEEQAVASLRQTEANLRQAKADLELAKIEAKRRQTLYKQGVIPATERDTYNNRVIQAQVGVKVAQEN
VKTAQDQIAVSKAGVVSNQARLLNTVIAREDTQLVSPINGIVAYMNIREGEYWSPSRVQSATSYQAAIESVPIVVVDPNS
FEVAFELPASEGSLLRPNQPAYVALDDDISQAFVQGLNQSNLVSVSKARGKVFSVTPAVTPGGRAVQVRVRITEGRENLR
LGARVQTWIAAQSRSQAITLPFGSVITRDRKSYVFVVNEETGRVEQRPVVLDIEGLDRISIAQGLQPGELVVTEGSNRLV
NDSPVDVVDIEDPA

Specific function: The Emr Locus Confers Resistance To Substances Of High Hydrophobicity. Emra Probably Participate In A Transport System To Extrude Toxins And Drugs From The Cell. [C]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Inner Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 54235; Mature: 54235

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTDERTPKDTGDLANTDTPSQLELDIQVPGDKQPPHSRPSVFSKKSPWPIAILVMLVIA
CCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
GLFGWRLYNNSQSPAVSEPETTSTAKLPVRAVRAQLSPIRRWVTSPDGDVRAERYKQLIF
HHHHHEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
ESSGEVTQLAKINGRFLREGDRVGKGQLLATLDDRKYQSDIRAAAADREVAKRTEEQAVA
CCCCCEEEHHHHCCHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
SLRQTEANLRQAKADLELAKIEAKRRQTLYKQGVIPATERDTYNNRVIQAQVGVKVAQEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHHHH
VKTAQDQIAVSKAGVVSNQARLLNTVIAREDTQLVSPINGIVAYMNIREGEYWSPSRVQS
HHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHCCCCCEEEEEEECCCCCCCHHHHHH
ATSYQAAIESVPIVVVDPNSFEVAFELPASEGSLLRPNQPAYVALDDDISQAFVQGLNQS
HHHHHHHHHHCCEEEECCCCEEEEEECCCCCCCEECCCCCEEEEECCHHHHHHHHCCCCC
NLVSVSKARGKVFSVTPAVTPGGRAVQVRVRITEGRENLRLGARVQTWIAAQSRSQAITL
CEEEEECCCCEEEEECCCCCCCCCEEEEEEEEECCCCCCEECCHHHHHHHHCCCCCEEEE
PFGSVITRDRKSYVFVVNEETGRVEQRPVVLDIEGLDRISIAQGLQPGELVVTEGSNRLV
CCHHHHCCCCCCEEEEEECCCCCCCCCCEEEEECCCCHHHHHHCCCCCCEEEECCCCCCC
NDSPVDVVDIEDPA
CCCCCEEEECCCCC
>Mature Secondary Structure
MKTDERTPKDTGDLANTDTPSQLELDIQVPGDKQPPHSRPSVFSKKSPWPIAILVMLVIA
CCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
GLFGWRLYNNSQSPAVSEPETTSTAKLPVRAVRAQLSPIRRWVTSPDGDVRAERYKQLIF
HHHHHEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
ESSGEVTQLAKINGRFLREGDRVGKGQLLATLDDRKYQSDIRAAAADREVAKRTEEQAVA
CCCCCEEEHHHHCCHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
SLRQTEANLRQAKADLELAKIEAKRRQTLYKQGVIPATERDTYNNRVIQAQVGVKVAQEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHHHH
VKTAQDQIAVSKAGVVSNQARLLNTVIAREDTQLVSPINGIVAYMNIREGEYWSPSRVQS
HHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHCCCCCEEEEEEECCCCCCCHHHHHH
ATSYQAAIESVPIVVVDPNSFEVAFELPASEGSLLRPNQPAYVALDDDISQAFVQGLNQS
HHHHHHHHHHCCEEEECCCCEEEEEECCCCCCCEECCCCCEEEEECCHHHHHHHHCCCCC
NLVSVSKARGKVFSVTPAVTPGGRAVQVRVRITEGRENLRLGARVQTWIAAQSRSQAITL
CEEEEECCCCEEEEECCCCCCCCCEEEEEEEEECCCCCCEECCHHHHHHHHCCCCCEEEE
PFGSVITRDRKSYVFVVNEETGRVEQRPVVLDIEGLDRISIAQGLQPGELVVTEGSNRLV
CCHHHHCCCCCCEEEEEECCCCCCCCCCEEEEECCCCHHHHHHCCCCCCEEEECCCCCCC
NDSPVDVVDIEDPA
CCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA