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The map label for this gene is rpiA [H]

Identifier: 158335565

GI number: 158335565

Start: 2421138

End: 2421845

Strand: Direct

Name: rpiA [H]

Synonym: AM1_2415

Alternate gene names: 158335565

Gene position: 2421138-2421845 (Clockwise)

Preceding gene: 158335558

Following gene: 158335571

Centisome position: 37.23

GC content: 49.01

Gene sequence:

>708_bases
ATGAGCGCAGTTGATCCCGTTAAGTTAATGAAACAACAGGTGGGTAAAGCCGCTGCCGATCGGGTTCAGTCTGGCTCAAT
CGTGGGGTTAGGCACTGGGTCTACCACCGCCTTTGCGATTCAGTTTTTGGGTGATCGGATTAAGTCAGGTGCATTAACGG
ATATCAAAGGTATTCCCACTTCCTTCCAAGCTTCTGTGTTAGCGAAGCAGTATGGCATTCCCCTCACCACCCTAGATGAA
GTGGATCGGATTCATATCGGCATTGATGGTGCCGATGAAGTGGATCCGCAGAAGAATTTAATCAAAGGTGGTGGCGCAGC
TCATACCCGCGAAAAGGTCGTGGATTCCCTAGCTGAGCAGTTTATTGTGGTGGTCGATCAATCCAAAATTGTCGATAAAT
TAGGGTCCACTTTCCCGGTCCCGGTGGAAGTATTGCCAATGGCGATCGCACCAGTCGTCAAAGCCTTAGAGAAGCTCGGT
GGTAAGCCCGAACTGCGGATGGGTATCAAAAAAGACGGTCCTGTGATTACCGACCAGGGCAATATGGTGCTGGACGTCAC
CTTTAGCGATATTCCTAATCCCCCCGAACTGGAGAAAACCATTAACAATATTCCAGGAGTTCTGGAAAACGGCATCTTCG
TGGGCATGACTGACATTGTTTTAATTGGCGAAATCAAAGATGGCAATCCCACCGTCCGTGAGATGTAA

Upstream 100 bases:

>100_bases
TTTCTGCGCTATCGCTTGAGAATGGTCTAGGCAGGTGTACCGCTTTACGTCATGCTAGAAATCGTCAGTTTTCGCAAGCA
GCTTTTTTAGGAGGTTCAGT

Downstream 100 bases:

>100_bases
TCTCCCATCGTTATCAAGGAAGTATGGGTGATACTTCCTTCTGATCATTTCACCTCCGGCTACCTTCGGGGGTATATTTT
TTCCCTTCCTGTGGAGCCTC

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MSAVDPVKLMKQQVGKAAADRVQSGSIVGLGTGSTTAFAIQFLGDRIKSGALTDIKGIPTSFQASVLAKQYGIPLTTLDE
VDRIHIGIDGADEVDPQKNLIKGGGAAHTREKVVDSLAEQFIVVVDQSKIVDKLGSTFPVPVEVLPMAIAPVVKALEKLG
GKPELRMGIKKDGPVITDQGNMVLDVTFSDIPNPPELEKTINNIPGVLENGIFVGMTDIVLIGEIKDGNPTVREM

Sequences:

>Translated_235_residues
MSAVDPVKLMKQQVGKAAADRVQSGSIVGLGTGSTTAFAIQFLGDRIKSGALTDIKGIPTSFQASVLAKQYGIPLTTLDE
VDRIHIGIDGADEVDPQKNLIKGGGAAHTREKVVDSLAEQFIVVVDQSKIVDKLGSTFPVPVEVLPMAIAPVVKALEKLG
GKPELRMGIKKDGPVITDQGNMVLDVTFSDIPNPPELEKTINNIPGVLENGIFVGMTDIVLIGEIKDGNPTVREM
>Mature_234_residues
SAVDPVKLMKQQVGKAAADRVQSGSIVGLGTGSTTAFAIQFLGDRIKSGALTDIKGIPTSFQASVLAKQYGIPLTTLDEV
DRIHIGIDGADEVDPQKNLIKGGGAAHTREKVVDSLAEQFIVVVDQSKIVDKLGSTFPVPVEVLPMAIAPVVKALEKLGG
KPELRMGIKKDGPVITDQGNMVLDVTFSDIPNPPELEKTINNIPGVLENGIFVGMTDIVLIGEIKDGNPTVREM

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=237, Percent_Identity=42.1940928270042, Blast_Score=178, Evalue=4e-45,
Organism=Escherichia coli, GI1789280, Length=216, Percent_Identity=48.1481481481481, Blast_Score=166, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17551758, Length=236, Percent_Identity=36.0169491525424, Blast_Score=157, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6324669, Length=243, Percent_Identity=33.7448559670782, Blast_Score=115, Evalue=5e-27,
Organism=Drosophila melanogaster, GI281364072, Length=205, Percent_Identity=44.8780487804878, Blast_Score=156, Evalue=9e-39,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 24847; Mature: 24716

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVDPVKLMKQQVGKAAADRVQSGSIVGLGTGSTTAFAIQFLGDRIKSGALTDIKGIPT
CCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
SFQASVLAKQYGIPLTTLDEVDRIHIGIDGADEVDPQKNLIKGGGAAHTREKVVDSLAEQ
HHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHH
FIVVVDQSKIVDKLGSTFPVPVEVLPMAIAPVVKALEKLGGKPELRMGIKKDGPVITDQG
EEEEECHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCEEECCC
NMVLDVTFSDIPNPPELEKTINNIPGVLENGIFVGMTDIVLIGEIKDGNPTVREM
CEEEEEEECCCCCCHHHHHHHHHCCHHHHCCEEEEEEEEEEEEEECCCCCHHCCC
>Mature Secondary Structure 
SAVDPVKLMKQQVGKAAADRVQSGSIVGLGTGSTTAFAIQFLGDRIKSGALTDIKGIPT
CCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
SFQASVLAKQYGIPLTTLDEVDRIHIGIDGADEVDPQKNLIKGGGAAHTREKVVDSLAEQ
HHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHH
FIVVVDQSKIVDKLGSTFPVPVEVLPMAIAPVVKALEKLGGKPELRMGIKKDGPVITDQG
EEEEECHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCEEECCC
NMVLDVTFSDIPNPPELEKTINNIPGVLENGIFVGMTDIVLIGEIKDGNPTVREM
CEEEEEEECCCCCCHHHHHHHHHCCHHHHCCEEEEEEEEEEEEEECCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]