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The map label for this gene is ppa [H]

Identifier: 158335459

GI number: 158335459

Start: 2306358

End: 2306870

Strand: Reverse

Name: ppa [H]

Synonym: AM1_2307

Alternate gene names: 158335459

Gene position: 2306870-2306358 (Counterclockwise)

Preceding gene: 158335460

Following gene: 158335458

Centisome position: 35.47

GC content: 44.83

Gene sequence:

>513_bases
GTGGATTTATCTTTAATACCCGCTCAGCCTAAACCGGGCTTGATCAATGTCTTGATTGAAATTCCTGCAGGCAGCAAAAA
CAAATACGAATTTGATAAGGACATGAATGCCTTTGCTTTGGATCGGGTGCTATTTGCTTCTGTGCAATATCCCTATGACT
ATGGGTTTATTCCCAATACCTTGGCAGATGATGGCGATCCCCTAGATGGCATGGTGATCATGGATCAGCCGACCTTCCCT
GGTTGTGTGATTACCGCCCGTCCCATTGGCATGTTGGAAATGATTGATGGTGGCGATCGCGATGAGAAAATTCTCTGCGT
ACCTGAGGAAGATCCTCGCTATGCCGATGTCAAATCTTTGGCTGATGTGGCCTCTCACCGTTTAGATGAAATCGCTGAGT
TTTTCCGCACCTATAAAAACCTCGAGAAAAAAGTTACAGAAATTTTAGGGTGGCAAGATGTGGATAAGGTCAATCCTTTA
GTGGCTGAGTGCATTAAAGCTGGCCAAAAATAG

Upstream 100 bases:

>100_bases
TACGGCGCTGTCATTGTCTATTACGCGAAATATTTTAGGAAATCTGCGCCGGAAACAAAGGTCTTGTAGGCCATCCCACC
CTTACATCTGGAGAACAATT

Downstream 100 bases:

>100_bases
GTCGAGAGACTGTAAAGGCTAGCGTTTTATAGGTGTATTAATTCTTTTTTTTAGGTATAACCACACCTTAAGATCTCAGC
CTTACCTCTCTCCTACTCTC

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 170; Mature: 170

Protein sequence:

>170_residues
MDLSLIPAQPKPGLINVLIEIPAGSKNKYEFDKDMNAFALDRVLFASVQYPYDYGFIPNTLADDGDPLDGMVIMDQPTFP
GCVITARPIGMLEMIDGGDRDEKILCVPEEDPRYADVKSLADVASHRLDEIAEFFRTYKNLEKKVTEILGWQDVDKVNPL
VAECIKAGQK

Sequences:

>Translated_170_residues
MDLSLIPAQPKPGLINVLIEIPAGSKNKYEFDKDMNAFALDRVLFASVQYPYDYGFIPNTLADDGDPLDGMVIMDQPTFP
GCVITARPIGMLEMIDGGDRDEKILCVPEEDPRYADVKSLADVASHRLDEIAEFFRTYKNLEKKVTEILGWQDVDKVNPL
VAECIKAGQK
>Mature_170_residues
MDLSLIPAQPKPGLINVLIEIPAGSKNKYEFDKDMNAFALDRVLFASVQYPYDYGFIPNTLADDGDPLDGMVIMDQPTFP
GCVITARPIGMLEMIDGGDRDEKILCVPEEDPRYADVKSLADVASHRLDEIAEFFRTYKNLEKKVTEILGWQDVDKVNPL
VAECIKAGQK

Specific function: Hydrolyzes PPi generated in anabolic reactions [H]

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=176, Percent_Identity=38.0681818181818, Blast_Score=103, Evalue=6e-24,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 18968; Mature: 18968

Theoretical pI: Translated: 4.23; Mature: 4.23

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLSLIPAQPKPGLINVLIEIPAGSKNKYEFDKDMNAFALDRVLFASVQYPYDYGFIPNT
CCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
LADDGDPLDGMVIMDQPTFPGCVITARPIGMLEMIDGGDRDEKILCVPEEDPRYADVKSL
CCCCCCCCCCEEEEECCCCCCEEEEECCCCEEEECCCCCCCCEEEEECCCCCCHHHHHHH
ADVASHRLDEIAEFFRTYKNLEKKVTEILGWQDVDKVNPLVAECIKAGQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHCCCC
>Mature Secondary Structure
MDLSLIPAQPKPGLINVLIEIPAGSKNKYEFDKDMNAFALDRVLFASVQYPYDYGFIPNT
CCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
LADDGDPLDGMVIMDQPTFPGCVITARPIGMLEMIDGGDRDEKILCVPEEDPRYADVKSL
CCCCCCCCCCEEEEECCCCCCEEEEECCCCEEEECCCCCCCCEEEEECCCCCCHHHHHHH
ADVASHRLDEIAEFFRTYKNLEKKVTEILGWQDVDKVNPLVAECIKAGQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]