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The map label for this gene is yhdP [H]

Identifier: 158335336

GI number: 158335336

Start: 2183026

End: 2184108

Strand: Direct

Name: yhdP [H]

Synonym: AM1_2181

Alternate gene names: 158335336

Gene position: 2183026-2184108 (Clockwise)

Preceding gene: 158335333

Following gene: 158335338

Centisome position: 33.57

GC content: 47.65

Gene sequence:

>1083_bases
GTGGCTAGTACAGTCAGGCCCTTATTAGGAGATGTTCGCCTGGATCTAATGATCTTGGTGATTTTGCTATTTTTATCTGC
TTTCTTTGCCGGATCTGAAACTGCCATCACGGCCCTCGACAACCTGAAGCTCAGGGCTCTAATGAAAGCAGAAGGGGATC
CTGATGGGCTCTACCGACTGGTGCTAGAGAAACGGGCTCGCTTTATCACAACCCTGCTGGTGGGCAACAATTTGGTCAAC
AACTTTGCGGCCATTTTAACCAGCAATTTATTTGTGATTTGGTTTGGAGGGGCAGGGGTTGGATTGGCAACAGCTGTGGT
CACATTCTTGCTGTTACTGTTCGGTGAAATCACCCCCAAATCCTTAGCTGTCAATAACGCCATGCCCATTTTTCAATGGG
TGGTGCGCCCTATCTACTGGTTGTCGGTTTTGTTACTACCGATCATTCGTCTGTTTGAATCTATCGTGCAGGTGGTGATT
CGTTTTTTCCAAAGTGGTTTGAAACAACAAAATGAATCCCTGCAAGATTTGCAGCTGTTGATTGAAGTGCTTGGGGGGCG
AGGGCAGCTTGATTTACAGAAACGCCAACTCCTCAACAAAGCGTTGATGCTGGATAGCTTGACGGTGCGCCAAGTCGTCA
AACCCCGGGTAGAAATGCAGACCGTGGACCATGAAGCCACCATGCAAGACGTGATTGATATTTGCTTAGAGAGCGGATAT
TCACGGATTCCGGTTCAAGAAGAATCCAAAGACTCCATTGTAGGAGTGATCCACTTAAAAAGCGCCGTTCAGCACCTTAA
AACCCAGGGTAATGAAGTCGTGACGGCAGCGATGGATCCACCTGTTTATATTCCCGAAACCAAGCGGGTTGCCGATCTCA
TGAAAGAGATGTTACATCAACGTCTTCATTTAGCCATTGCGGTCGATGAGTATGGCGGTACGGTGGGTTTAGTGACCTTA
GAAGATTTGCTAGAGGAGTTGGTGGGCGAAATCTATGATGAAAGTGATTCCCCTAGCTCTACAAAGCCGCGACGATATCT
AGGATTAGGATTATTGTCCCGACCCGGATCCACCTCTTCTTAG

Upstream 100 bases:

>100_bases
GCGATTAAAATATATCTCTGGACGATTATTTCAACGATATACTTGCATTCTGACCCTCATATTCAAATGAATGGTTCTGT
TGCCTTTCTCCCAATTATCA

Downstream 100 bases:

>100_bases
TCGGTGGACCGTAGACGGGATTGAGCAATTTGCCAACTGAGAAAAATGACCGGCAATAGCCCCACCAACACGATGGCTAA
AGCAGGGGCTGCCGCTTCCA

Product: CBS domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MASTVRPLLGDVRLDLMILVILLFLSAFFAGSETAITALDNLKLRALMKAEGDPDGLYRLVLEKRARFITTLLVGNNLVN
NFAAILTSNLFVIWFGGAGVGLATAVVTFLLLLFGEITPKSLAVNNAMPIFQWVVRPIYWLSVLLLPIIRLFESIVQVVI
RFFQSGLKQQNESLQDLQLLIEVLGGRGQLDLQKRQLLNKALMLDSLTVRQVVKPRVEMQTVDHEATMQDVIDICLESGY
SRIPVQEESKDSIVGVIHLKSAVQHLKTQGNEVVTAAMDPPVYIPETKRVADLMKEMLHQRLHLAIAVDEYGGTVGLVTL
EDLLEELVGEIYDESDSPSSTKPRRYLGLGLLSRPGSTSS

Sequences:

>Translated_360_residues
MASTVRPLLGDVRLDLMILVILLFLSAFFAGSETAITALDNLKLRALMKAEGDPDGLYRLVLEKRARFITTLLVGNNLVN
NFAAILTSNLFVIWFGGAGVGLATAVVTFLLLLFGEITPKSLAVNNAMPIFQWVVRPIYWLSVLLLPIIRLFESIVQVVI
RFFQSGLKQQNESLQDLQLLIEVLGGRGQLDLQKRQLLNKALMLDSLTVRQVVKPRVEMQTVDHEATMQDVIDICLESGY
SRIPVQEESKDSIVGVIHLKSAVQHLKTQGNEVVTAAMDPPVYIPETKRVADLMKEMLHQRLHLAIAVDEYGGTVGLVTL
EDLLEELVGEIYDESDSPSSTKPRRYLGLGLLSRPGSTSS
>Mature_359_residues
ASTVRPLLGDVRLDLMILVILLFLSAFFAGSETAITALDNLKLRALMKAEGDPDGLYRLVLEKRARFITTLLVGNNLVNN
FAAILTSNLFVIWFGGAGVGLATAVVTFLLLLFGEITPKSLAVNNAMPIFQWVVRPIYWLSVLLLPIIRLFESIVQVVIR
FFQSGLKQQNESLQDLQLLIEVLGGRGQLDLQKRQLLNKALMLDSLTVRQVVKPRVEMQTVDHEATMQDVIDICLESGYS
RIPVQEESKDSIVGVIHLKSAVQHLKTQGNEVVTAAMDPPVYIPETKRVADLMKEMLHQRLHLAIAVDEYGGTVGLVTLE
DLLEELVGEIYDESDSPSSTKPRRYLGLGLLSRPGSTSS

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=257, Percent_Identity=27.2373540856031, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI94681046, Length=340, Percent_Identity=26.4705882352941, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI40068053, Length=344, Percent_Identity=26.1627906976744, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI40068055, Length=344, Percent_Identity=26.1627906976744, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI40068051, Length=256, Percent_Identity=26.5625, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI145693175, Length=323, Percent_Identity=29.1021671826625, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786879, Length=151, Percent_Identity=35.0993377483444, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI1790664, Length=333, Percent_Identity=21.021021021021, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1788119, Length=152, Percent_Identity=28.2894736842105, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71980512, Length=363, Percent_Identity=26.4462809917355, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324512, Length=334, Percent_Identity=22.4550898203593, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 39847; Mature: 39716

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASTVRPLLGDVRLDLMILVILLFLSAFFAGSETAITALDNLKLRALMKAEGDPDGLYRL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
VLEKRARFITTLLVGNNLVNNFAAILTSNLFVIWFGGAGVGLATAVVTFLLLLFGEITPK
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCH
SLAVNNAMPIFQWVVRPIYWLSVLLLPIIRLFESIVQVVIRFFQSGLKQQNESLQDLQLL
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
IEVLGGRGQLDLQKRQLLNKALMLDSLTVRQVVKPRVEMQTVDHEATMQDVIDICLESGY
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHCCC
SRIPVQEESKDSIVGVIHLKSAVQHLKTQGNEVVTAAMDPPVYIPETKRVADLMKEMLHQ
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCEECCCHHHHHHHHHHHHHH
RLHLAIAVDEYGGTVGLVTLEDLLEELVGEIYDESDSPSSTKPRRYLGLGLLSRPGSTSS
HHHHEEEEECCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCHHHCCCCCCCC
>Mature Secondary Structure 
ASTVRPLLGDVRLDLMILVILLFLSAFFAGSETAITALDNLKLRALMKAEGDPDGLYRL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
VLEKRARFITTLLVGNNLVNNFAAILTSNLFVIWFGGAGVGLATAVVTFLLLLFGEITPK
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCH
SLAVNNAMPIFQWVVRPIYWLSVLLLPIIRLFESIVQVVIRFFQSGLKQQNESLQDLQLL
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
IEVLGGRGQLDLQKRQLLNKALMLDSLTVRQVVKPRVEMQTVDHEATMQDVIDICLESGY
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHCCC
SRIPVQEESKDSIVGVIHLKSAVQHLKTQGNEVVTAAMDPPVYIPETKRVADLMKEMLHQ
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCEECCCHHHHHHHHHHHHHH
RLHLAIAVDEYGGTVGLVTLEDLLEELVGEIYDESDSPSSTKPRRYLGLGLLSRPGSTSS
HHHHEEEEECCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]