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The map label for this gene is mhpA [C]

Identifier: 158335321

GI number: 158335321

Start: 2165374

End: 2166567

Strand: Direct

Name: mhpA [C]

Synonym: AM1_2165

Alternate gene names: 158335321

Gene position: 2165374-2166567 (Clockwise)

Preceding gene: 158335320

Following gene: 158335325

Centisome position: 33.29

GC content: 50.25

Gene sequence:

>1194_bases
ATGCAATCTGAACAGTCCCCTTACCTCAATAAAGTTGGCATTATCGGTGCAGGCCCCGCAGGACTCGCCACAGCCATCGC
CCTCAGAAAGCAAGGCATAGAAGTCCATATCTATGAACGCGCCACAGCCTTGCGGCCCATCGGCGCAGGCGTCACCCTCT
CCCCCAACGGCATCAGAAGCCTAGCCGCCATTGATACCGATATTGTTCAACAACTACAACAGCAAGGCTCCCAACTCAAT
CGCTTCCGCATCAGAACCGCTAAAGGATGGCCCCTCCTCAACCAACCCGTCAAAGATGACGATTACGATCAGCCCTTTCT
AGCCATTCGCTGGTTTAGCCTCCAAGAAATAATGAGGGCCAAACTCCCCCCAGAAATTCTTCACCTCAATCATCAACTCA
CTCACTTTGAGCAAACCCATCAAAACGTCAATCTGTCCTTTGCCAACGGTGAAATGGCAACCGTTGATCTACTGATTGGC
GCAGACGGCATTCGTTCCATCGTCCGCAAACAACTCTTTGACCTAGAAGACCCAGCTTATGGTGGTTGGATGACCTGGCG
CGGCGTCCAAAAATATCAGCATCCCTTGCTTCCCCCTCACCACACCACGATTTTTGCCAAACGAGGCAAAAGTTTAATCC
TCCTAGATAACGGCCAAGGCTATGTCTCATGGGCATTAGAGATACCCATGCCCACCATTCATCGATCCCAACATCCCGAA
GCAGCAAAAACCCGAGTCCTACAGGAACTCTCCAAATGGCATCCTACCTTACAAGAACTGGTGAACCTCACAGATGCAGA
CACCATCGTTGAAAGACCCGTATGCGAGCCTATGATCTTGCCTCAATGGAGCAACGGCAGAGTCACCCTCGTCGGGGATG
CCGCCCATCCAATGGCACCCTTCTTAGGCCAAGGCACTAACACCACCTTCGAAGACGTGTGGGCCTTATCCACCTATTTA
TCTCAACAGGGCAATCTAGCAAACGCTTTGAAAAACTACGAAAACAACCGTATTGAGCGCGCCCATACTATTCAATATCG
GACAATGTACTCCGCTGCTCAAATGCGCAACCCTTTCCTACGACCTCGATGGTTCAAAACATCCTTAGGAAAAGTACCAG
ACCAGGCCAAAGTCAGCGAAAAGGCATTTTCAGATTGGCTCTACCAGTATGAGCTAACAACTGAATCAACTTAA

Upstream 100 bases:

>100_bases
AAATGGTAAAAAACAGATTCGACAGATCGAATTTGTGGGTGAACGCTTTGACGTGATGAGTGTCAGACATTGGCGGGAGA
AAGCTCTAAAGCCGTAATCT

Downstream 100 bases:

>100_bases
CTCGCCTCCGTCAGGCCAAGAAAAGACTGGAGTCCTATACGCATTTACACAAAAATAAAGCGCCCCCGGAGGAGCGCTTT
ATTCAAATTAGGTTCTCAGT

Product: salicylate 1-monooxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MQSEQSPYLNKVGIIGAGPAGLATAIALRKQGIEVHIYERATALRPIGAGVTLSPNGIRSLAAIDTDIVQQLQQQGSQLN
RFRIRTAKGWPLLNQPVKDDDYDQPFLAIRWFSLQEIMRAKLPPEILHLNHQLTHFEQTHQNVNLSFANGEMATVDLLIG
ADGIRSIVRKQLFDLEDPAYGGWMTWRGVQKYQHPLLPPHHTTIFAKRGKSLILLDNGQGYVSWALEIPMPTIHRSQHPE
AAKTRVLQELSKWHPTLQELVNLTDADTIVERPVCEPMILPQWSNGRVTLVGDAAHPMAPFLGQGTNTTFEDVWALSTYL
SQQGNLANALKNYENNRIERAHTIQYRTMYSAAQMRNPFLRPRWFKTSLGKVPDQAKVSEKAFSDWLYQYELTTEST

Sequences:

>Translated_397_residues
MQSEQSPYLNKVGIIGAGPAGLATAIALRKQGIEVHIYERATALRPIGAGVTLSPNGIRSLAAIDTDIVQQLQQQGSQLN
RFRIRTAKGWPLLNQPVKDDDYDQPFLAIRWFSLQEIMRAKLPPEILHLNHQLTHFEQTHQNVNLSFANGEMATVDLLIG
ADGIRSIVRKQLFDLEDPAYGGWMTWRGVQKYQHPLLPPHHTTIFAKRGKSLILLDNGQGYVSWALEIPMPTIHRSQHPE
AAKTRVLQELSKWHPTLQELVNLTDADTIVERPVCEPMILPQWSNGRVTLVGDAAHPMAPFLGQGTNTTFEDVWALSTYL
SQQGNLANALKNYENNRIERAHTIQYRTMYSAAQMRNPFLRPRWFKTSLGKVPDQAKVSEKAFSDWLYQYELTTEST
>Mature_397_residues
MQSEQSPYLNKVGIIGAGPAGLATAIALRKQGIEVHIYERATALRPIGAGVTLSPNGIRSLAAIDTDIVQQLQQQGSQLN
RFRIRTAKGWPLLNQPVKDDDYDQPFLAIRWFSLQEIMRAKLPPEILHLNHQLTHFEQTHQNVNLSFANGEMATVDLLIG
ADGIRSIVRKQLFDLEDPAYGGWMTWRGVQKYQHPLLPPHHTTIFAKRGKSLILLDNGQGYVSWALEIPMPTIHRSQHPE
AAKTRVLQELSKWHPTLQELVNLTDADTIVERPVCEPMILPQWSNGRVTLVGDAAHPMAPFLGQGTNTTFEDVWALSTYL
SQQGNLANALKNYENNRIERAHTIQYRTMYSAAQMRNPFLRPRWFKTSLGKVPDQAKVSEKAFSDWLYQYELTTEST

Specific function: Catalyzes the oxidative decarboxylation of 6- hydroxynicotinic acid to 2,5-dihydroxypyridine. Uses NADH in preference to NADPH as an electron donor [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI187960045, Length=382, Percent_Identity=24.869109947644, Blast_Score=79, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6319372, Length=377, Percent_Identity=25.4641909814324, Blast_Score=90, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: =1.14.13.114 [H]

Molecular weight: Translated: 44888; Mature: 44888

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSEQSPYLNKVGIIGAGPAGLATAIALRKQGIEVHIYERATALRPIGAGVTLSPNGIRS
CCCCCCCCHHCCCEEECCHHHHHHHHHHHHCCCEEEEEECHHHCCCCCCCCEECCCHHHH
LAAIDTDIVQQLQQQGSQLNRFRIRTAKGWPLLNQPVKDDDYDQPFLAIRWFSLQEIMRA
HHHHHHHHHHHHHHHCCHHCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHH
KLPPEILHLNHQLTHFEQTHQNVNLSFANGEMATVDLLIGADGIRSIVRKQLFDLEDPAY
CCCHHHHHCCCHHHHHHHHHCCEEEEECCCCEEEEEEEECCHHHHHHHHHHHHCCCCCCC
GGWMTWRGVQKYQHPLLPPHHTTIFAKRGKSLILLDNGQGYVSWALEIPMPTIHRSQHPE
CCCHHHHHHHHHCCCCCCCCCCEEEEECCCEEEEEECCCCEEEEEEECCCCCCCCCCCCH
AAKTRVLQELSKWHPTLQELVNLTDADTIVERPVCEPMILPQWSNGRVTLVGDAAHPMAP
HHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHCCCCCCEECCCCCCCEEEEEECCCCCCHH
FLGQGTNTTFEDVWALSTYLSQQGNLANALKNYENNRIERAHTIQYRTMYSAAQMRNPFL
HHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHEEHHHHHHHHHHHCCCCC
RPRWFKTSLGKVPDQAKVSEKAFSDWLYQYELTTEST
CCCHHHHHHCCCCCHHHHHHHHHHHHEEEEEEECCCC
>Mature Secondary Structure
MQSEQSPYLNKVGIIGAGPAGLATAIALRKQGIEVHIYERATALRPIGAGVTLSPNGIRS
CCCCCCCCHHCCCEEECCHHHHHHHHHHHHCCCEEEEEECHHHCCCCCCCCEECCCHHHH
LAAIDTDIVQQLQQQGSQLNRFRIRTAKGWPLLNQPVKDDDYDQPFLAIRWFSLQEIMRA
HHHHHHHHHHHHHHHCCHHCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHH
KLPPEILHLNHQLTHFEQTHQNVNLSFANGEMATVDLLIGADGIRSIVRKQLFDLEDPAY
CCCHHHHHCCCHHHHHHHHHCCEEEEECCCCEEEEEEEECCHHHHHHHHHHHHCCCCCCC
GGWMTWRGVQKYQHPLLPPHHTTIFAKRGKSLILLDNGQGYVSWALEIPMPTIHRSQHPE
CCCHHHHHHHHHCCCCCCCCCCEEEEECCCEEEEEECCCCEEEEEEECCCCCCCCCCCCH
AAKTRVLQELSKWHPTLQELVNLTDADTIVERPVCEPMILPQWSNGRVTLVGDAAHPMAP
HHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHCCCCCCEECCCCCCCEEEEEECCCCCCHH
FLGQGTNTTFEDVWALSTYLSQQGNLANALKNYENNRIERAHTIQYRTMYSAAQMRNPFL
HHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHEEHHHHHHHHHHHCCCCC
RPRWFKTSLGKVPDQAKVSEKAFSDWLYQYELTTEST
CCCHHHHHHCCCCCHHHHHHHHHHHHEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA