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The map label for this gene is cbiX [H]

Identifier: 158335167

GI number: 158335167

Start: 1998174

End: 1999184

Strand: Reverse

Name: cbiX [H]

Synonym: AM1_2009

Alternate gene names: 158335167

Gene position: 1999184-1998174 (Counterclockwise)

Preceding gene: 158335168

Following gene: 158335165

Centisome position: 30.74

GC content: 49.65

Gene sequence:

>1011_bases
TTGGTGGTCAGACCTGCCCCCCTCAGTTTGCCGATCGCTGGTGATCTAACGCCATTACCCCTTCAAAGACCTTTACTTAT
GATTGGCCATGGCACCCGAAATCCCAACGGCAGACAATGTTTCCTAGATTTTGCAACCCTCTACCAGGAACTCGATCGAT
CAAGACCGGTGTTTCCCTGCTTTTTAGAACTGACGGGACCCAGTATTCAAGAAGTCGTCGATCACTGTGTTGAGCAAGGC
TATACGGAACTCTCGGCGCTACCGATTCTGCTATTTGCCGCCCGCCACAACAAGTTTGATGTCACCAACGAACTCGATCT
AGCCCGCAAACGCCATCCCCAGTTGAAATATCACTATGGCCGTCATTTTGGGATTACGCCTGGGATTTTAGACCTATGGA
AACAACGGTTAGAACTACTGGATAACCCCGAGCATAATCCTCAAGGCATTTCCCGTGAAGAGACTGTTTTGCTATTTGTG
GGACGAGGCTCCAGCGACCCTGATGCCAATAGCGATGTCAGTAAAATGGCCCGCATCCTCTGGGAAGGCAGTAACTATCA
GACTGTGGAAACCTGCTTTATTGGCATTACCCATCCCCGATTGGAAGAAGGATTCCGACGCGCACGGCTGTATCAGCCTA
AGCGCATTGTTGTACTGCCCTATTTTCTGTTTACGGGCACGTTGGTGGAAAAGATTTTTGATATCTCAGCCCATCAGCAA
GTGGCCTATCCAGATATTCAAGTGACTTGCTTGCCGGAAATGGGGCTGCATCCGGCCTTGGTTCAGGTGTTGCGCCAGCG
GGAATTGGAAACTCAGTTAGGGCAAGTCCAGATGAATTGTGAGCTATGTAAATTTCGGCTGGCAGCTCTCAATGGTGAAG
AACCCCATAGCCATAGTCATGATCATGGCCATAGCCACGATCACGGCCATCATGGTCACGGGCATAGCCACGCCACTATC
AATGTGGATAAAGAAGCGGATTACCACAATCGTATTTGGCAAGTACCTTAA

Upstream 100 bases:

>100_bases
AACCCATAAGATTGCTTAGCCATCTCGTGGGGAATCCTCAGTCAACGCTTGTGATTCACAGGCAGGGAGTTCTTTAATGT
CCATTGCTCATATGCCAGAC

Downstream 100 bases:

>100_bases
ACTGCGTGGGTTTGTAACTGTCTAAGGGGTGGCTCATCTCGGTGGTGAGGGCTTGTCCCTGCCGTTAGTTGGTGAATCCA
GCCGAGGTATCGGGTGCTGA

Product: sirohydrochlorin cobaltochelatase CbiX

Products: NA

Alternate protein names: CbiXL [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MVVRPAPLSLPIAGDLTPLPLQRPLLMIGHGTRNPNGRQCFLDFATLYQELDRSRPVFPCFLELTGPSIQEVVDHCVEQG
YTELSALPILLFAARHNKFDVTNELDLARKRHPQLKYHYGRHFGITPGILDLWKQRLELLDNPEHNPQGISREETVLLFV
GRGSSDPDANSDVSKMARILWEGSNYQTVETCFIGITHPRLEEGFRRARLYQPKRIVVLPYFLFTGTLVEKIFDISAHQQ
VAYPDIQVTCLPEMGLHPALVQVLRQRELETQLGQVQMNCELCKFRLAALNGEEPHSHSHDHGHSHDHGHHGHGHSHATI
NVDKEADYHNRIWQVP

Sequences:

>Translated_336_residues
MVVRPAPLSLPIAGDLTPLPLQRPLLMIGHGTRNPNGRQCFLDFATLYQELDRSRPVFPCFLELTGPSIQEVVDHCVEQG
YTELSALPILLFAARHNKFDVTNELDLARKRHPQLKYHYGRHFGITPGILDLWKQRLELLDNPEHNPQGISREETVLLFV
GRGSSDPDANSDVSKMARILWEGSNYQTVETCFIGITHPRLEEGFRRARLYQPKRIVVLPYFLFTGTLVEKIFDISAHQQ
VAYPDIQVTCLPEMGLHPALVQVLRQRELETQLGQVQMNCELCKFRLAALNGEEPHSHSHDHGHSHDHGHHGHGHSHATI
NVDKEADYHNRIWQVP
>Mature_336_residues
MVVRPAPLSLPIAGDLTPLPLQRPLLMIGHGTRNPNGRQCFLDFATLYQELDRSRPVFPCFLELTGPSIQEVVDHCVEQG
YTELSALPILLFAARHNKFDVTNELDLARKRHPQLKYHYGRHFGITPGILDLWKQRLELLDNPEHNPQGISREETVLLFV
GRGSSDPDANSDVSKMARILWEGSNYQTVETCFIGITHPRLEEGFRRARLYQPKRIVVLPYFLFTGTLVEKIFDISAHQQ
VAYPDIQVTCLPEMGLHPALVQVLRQRELETQLGQVQMNCELCKFRLAALNGEEPHSHSHDHGHSHDHGHHGHGHSHATI
NVDKEADYHNRIWQVP

Specific function: Chelates cobalt to the cobalamin precursor as part of the anaerobic pathway to cobalamin biosynthesis [H]

COG id: COG2138

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CbiX family. CbiXL subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002762 [H]

Pfam domain/function: PF01903 CbiX [H]

EC number: =4.99.1.3 [H]

Molecular weight: Translated: 38292; Mature: 38292

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS00028 ZINC_FINGER_C2H2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVRPAPLSLPIAGDLTPLPLQRPLLMIGHGTRNPNGRQCFLDFATLYQELDRSRPVFPC
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEHHHHHHHHHHHHHCCCCCEE
FLELTGPSIQEVVDHCVEQGYTELSALPILLFAARHNKFDVTNELDLARKRHPQLKYHYG
EEEECCCCHHHHHHHHHHCCCHHHHHHHHHEEECCCCCCCCCCHHHHHHHCCCCCEEECC
RHFGITPGILDLWKQRLELLDNPEHNPQGISREETVLLFVGRGSSDPDANSDVSKMARIL
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHH
WEGSNYQTVETCFIGITHPRLEEGFRRARLYQPKRIVVLPYFLFTGTLVEKIFDISAHQQ
HCCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCCCE
VAYPDIQVTCLPEMGLHPALVQVLRQRELETQLGQVQMNCELCKFRLAALNGEEPHSHSH
ECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHCCCCCCCCCCC
DHGHSHDHGHHGHGHSHATINVDKEADYHNRIWQVP
CCCCCCCCCCCCCCCCEEEEEECCCCCHHCCCCCCC
>Mature Secondary Structure
MVVRPAPLSLPIAGDLTPLPLQRPLLMIGHGTRNPNGRQCFLDFATLYQELDRSRPVFPC
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEHHHHHHHHHHHHHCCCCCEE
FLELTGPSIQEVVDHCVEQGYTELSALPILLFAARHNKFDVTNELDLARKRHPQLKYHYG
EEEECCCCHHHHHHHHHHCCCHHHHHHHHHEEECCCCCCCCCCHHHHHHHCCCCCEEECC
RHFGITPGILDLWKQRLELLDNPEHNPQGISREETVLLFVGRGSSDPDANSDVSKMARIL
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHH
WEGSNYQTVETCFIGITHPRLEEGFRRARLYQPKRIVVLPYFLFTGTLVEKIFDISAHQQ
HCCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCCCE
VAYPDIQVTCLPEMGLHPALVQVLRQRELETQLGQVQMNCELCKFRLAALNGEEPHSHSH
ECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHCCCCCCCCCCC
DHGHSHDHGHHGHGHSHATINVDKEADYHNRIWQVP
CCCCCCCCCCCCCCCCEEEEEECCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 12917443 [H]