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The map label for this gene is ribC [H]

Identifier: 158335142

GI number: 158335142

Start: 1977816

End: 1978484

Strand: Direct

Name: ribC [H]

Synonym: AM1_1983

Alternate gene names: 158335142

Gene position: 1977816-1978484 (Clockwise)

Preceding gene: 158335136

Following gene: 158335143

Centisome position: 30.41

GC content: 52.91

Gene sequence:

>669_bases
GTGTTTACAGGACTCATTCAAGGATTAGGCTATCTTCAACCCCAAGGCCCACAGCAAATTTTGGTAAAGTGCGGGGCTGT
GCCCTTTTGGGATGATCTGGCCATCGGCGATAGTGTCGCGGTGGATGGCGTCTGTTTAACCGTCGAGACGATCATTGCTC
AGGGGTTTGTCGTATCTGTTTCCCCAGAAACAGTGCAGCGCACCACCCTCTCCCAGCGGTTACATACCCACCAGGCCGTC
AATTTAGAACCGGCCCTCAGCGTCGGGGATCGGTTAGGGGGCCATTTTGTCACAGGCCATATTGACGATGTGGGGGTATT
CCAAGGGTTACAGCAAACCGATACCTCTTGGGAGTTAAGCTTCGCAGTACCGGATGCGATCGCACGCTTTATCATCCACA
AAGGCAGCGTAGCCATCAACGGTGTCAGTCTGACCGTTGCCGACTGTAACGAAAGCGGCACTCACTTCAAAGTCGCCGTC
ATTCCTCATAGCTTTGCCAACACCAACTTGAATACCTTGAGCCCAGGCGATCAGGTCAATATCGAAAACGATGTGTTAGG
CAAATATGTGGCTAAACTCCTGCACCTGCCAGATCCCCCCTCCTCAACTGCAGCTATGCCTGACATAACAACCGAGTTCC
TGACCACCCACGGCTTCGGTAGCCTGTAA

Upstream 100 bases:

>100_bases
TTTGAGAATCAAGATAAGATTCCCCGCTCCGATCCTAGCCAAGGCAATCGCAATTTGCCAATGTAGGAAATACTGATGTT
AATAATGGCTTGATAAGTAA

Downstream 100 bases:

>100_bases
TGGTAATGGGTTTTGTCCAGCCACCCATGCTATCAGACAGCACTCAATTTATACATTTTGCCCTTACCTTGCATGGGCAC
AAAGGCACCATCTCCAACAG

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MFTGLIQGLGYLQPQGPQQILVKCGAVPFWDDLAIGDSVAVDGVCLTVETIIAQGFVVSVSPETVQRTTLSQRLHTHQAV
NLEPALSVGDRLGGHFVTGHIDDVGVFQGLQQTDTSWELSFAVPDAIARFIIHKGSVAINGVSLTVADCNESGTHFKVAV
IPHSFANTNLNTLSPGDQVNIENDVLGKYVAKLLHLPDPPSSTAAMPDITTEFLTTHGFGSL

Sequences:

>Translated_222_residues
MFTGLIQGLGYLQPQGPQQILVKCGAVPFWDDLAIGDSVAVDGVCLTVETIIAQGFVVSVSPETVQRTTLSQRLHTHQAV
NLEPALSVGDRLGGHFVTGHIDDVGVFQGLQQTDTSWELSFAVPDAIARFIIHKGSVAINGVSLTVADCNESGTHFKVAV
IPHSFANTNLNTLSPGDQVNIENDVLGKYVAKLLHLPDPPSSTAAMPDITTEFLTTHGFGSL
>Mature_222_residues
MFTGLIQGLGYLQPQGPQQILVKCGAVPFWDDLAIGDSVAVDGVCLTVETIIAQGFVVSVSPETVQRTTLSQRLHTHQAV
NLEPALSVGDRLGGHFVTGHIDDVGVFQGLQQTDTSWELSFAVPDAIARFIIHKGSVAINGVSLTVADCNESGTHFKVAV
IPHSFANTNLNTLSPGDQVNIENDVLGKYVAKLLHLPDPPSSTAAMPDITTEFLTTHGFGSL

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=192, Percent_Identity=32.2916666666667, Blast_Score=86, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6319733, Length=216, Percent_Identity=34.2592592592593, Blast_Score=108, Evalue=7e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 23569; Mature: 23569

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00693 LUM_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGLIQGLGYLQPQGPQQILVKCGAVPFWDDLAIGDSVAVDGVCLTVETIIAQGFVVSV
CCHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEECCEEHHHHHHHHCCEEEEE
SPETVQRTTLSQRLHTHQAVNLEPALSVGDRLGGHFVTGHIDDVGVFQGLQQTDTSWELS
CHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEECCCCCHHHHCCHHHCCCCEEEE
FAVPDAIARFIIHKGSVAINGVSLTVADCNESGTHFKVAVIPHSFANTNLNTLSPGDQVN
EECHHHHHHHHHHCCCEEEECEEEEEEECCCCCCEEEEEEEECCCCCCCCCCCCCCCCCC
IENDVLGKYVAKLLHLPDPPSSTAAMPDITTEFLTTHGFGSL
CCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCC
>Mature Secondary Structure
MFTGLIQGLGYLQPQGPQQILVKCGAVPFWDDLAIGDSVAVDGVCLTVETIIAQGFVVSV
CCHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEECCEEHHHHHHHHCCEEEEE
SPETVQRTTLSQRLHTHQAVNLEPALSVGDRLGGHFVTGHIDDVGVFQGLQQTDTSWELS
CHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEECCCCCHHHHCCHHHCCCCEEEE
FAVPDAIARFIIHKGSVAINGVSLTVADCNESGTHFKVAVIPHSFANTNLNTLSPGDQVN
EECHHHHHHHHHHCCCEEEECEEEEEEECCCCCCEEEEEEEECCCCCCCCCCCCCCCCCC
IENDVLGKYVAKLLHLPDPPSSTAAMPDITTEFLTTHGFGSL
CCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]