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The map label for this gene is fdhA [H]

Identifier: 158334935

GI number: 158334935

Start: 1761541

End: 1763838

Strand: Reverse

Name: fdhA [H]

Synonym: AM1_1772

Alternate gene names: 158334935

Gene position: 1763838-1761541 (Counterclockwise)

Preceding gene: 158334937

Following gene: 158334934

Centisome position: 27.12

GC content: 53.66

Gene sequence:

>2298_bases
ATGACCGATTGGCAGCCGACGGCTTGTATTTTATGTTCCCGCAACTGCGGCCTCCAGGTCCAAGTCGCAGACGGCCATCT
CACCAAGATTCGTGGCGATAAAAACCACCCGGTTAGTGCAGGCTATATCTGCCAAAAAGCCGCCCAACTCGACCACTATC
AAAACAATGCCGATCGCCTCACCCAACCCCTTAAACGGCAGGAAGATGGATCCTATCAACCCATTGACTGGCAAACCGCT
ATTACCGAAATTGCCGCTCGCCTGCTGGATCTAAAGCAGACCTACGGCAAAGAGTGCCTCGCCTTTTATGGCGGGGGCGG
CCAAGGCAATCACCTCGGCTCCATGTACAGCAGCACCTTTCGCGATGCCTTGGAGATTCCCTACTACTATTCCGCCCTGG
CTCAGGAAAAAACCGGGGACTTTTGGGCGAATGGCAAGCTGTTTGGTCGTCAAAACTGCCATACCACCGAAGATATTGAA
CAGACAGAGTGCGTATTGTTTATTGGCACCAATCCTTGGCAAGCCCACGGCATCCGTAATGCCCGCCCCACCCTTAAACA
GATTGCCCAGGACGATCAGCGAACCATGATTGTGATCGATCCGCGCCGGACGGAAACGGCAGAGTTAGCGGATATTCATC
TGCAGTTGCGGCCTGGAACCGATGCCTTTTTACTATCAGCCATGCTGGCAATTCTGGTGCAGGAAGGCTGGGAAGATCAA
GCCTTTCTCCAGGAGCATACGATTGGATATACAGAGGTGCGGGCTTGTCTCCTAACCATTCCCATTGCGGATCATATTGA
ACGGGCTGGAGTAGATGCCGATCAGGTTTATGAGGCCGTGCGCCGCTTTGCCACCGCGAAGTCTGCCAATGTCCGGGTGG
ATTTGGGTTTGCAGCAAAGCCTCAACAGCACCCTCAATTCCTATCTAGAGAAACTGTTCTTTCTGCTAACGGGCAATTTA
GGCAAACCTGGCGGTAACAACTTCCATACCTTTTTCCTGCCTTGGGTTGGCCATTCTGATGCCGAGGCTAAAACGCTATG
CCAAACGAAGGCAACGGGTATCACGGAAATTGCCCAGCTATTTCCCCCCAATGTGTTGCCTGCTGAAATTGAGTCCGATC
ATCCTCAGCGTATCCGGGGCTTAATCGTCGATAGTGCCAATCCGGTGGTGTCCGGGGCAGATACCCAAGCCTATCAGCGT
GCCTTTCCCAAGCTGGATCTGCTGGTGGTTGTAGATGTGGCGATGACAGAGACGGCTCGCTATGCCGACTACATCCTGTC
GGCTGCGTCGCAGTTTGAAAAATGGGAAGCCGCCTTTTTTAATTTGGAATTTCCCACCAATGCCTTTCATTTACGAAAGC
CTCTGTTTGCTCCTTTAGCCGATACTCTGCCAGAGTCAGAAATCTATCGGCGATTGGCGGTTGCGATTGGGGCGATTCCT
GAACGCTATCCAGTGTTGGAACAGGTGGCTCGTTGGCATGGGCGGTGGCCTCAGCTAGGACTGTATCGAGTGGCTTTGGT
GGCGGCCATGGCCCTACAGCCTCAGCTGAGACGTACCGTTGCTTTTGCCTTGCAAGGATCCTTGGGCAAGACCTTACCGG
ATGACAGCATTGCCCCGTTTTGGGGGGTGAGCCAGCTTTATGTTCAGCACCATGGCGAAGCAGTGGCCCGGACGGGTTTG
CCTGGCCGAGGGGGGCGATTGGCAGAAGCATTATTTCAGCGGATTTTGCATGGCCATAGTGGCGCACCTATTAGCCAACA
TCGCTATGAAGAGACCTGGGCATTGATGGGCTACAAAGACCAAAAAGTGCGGTTAGTGATTTCTGAACTGATTGAGGAGT
TGCAGACCCTCTCCTCCCACCATGCCTGGCCAGAGTATCCCTTGATGCTGATTGCAGGTGAGCGCCGCATGTATAACGCC
AACACCATCTACCGTAATCCCCAATGGCGACAAAATGACGCTGAGGGGGTGCTCAAGATCCATCCTGTCGATGCTAAAGC
GTTAGCGCTAGCTGAAGGGAGTCATGCAGTGTGTGAATCCCCCTGGGGACAGCTGACGGTACAGGTCAAACTTTGCGATA
CCCTTCGTCCGGGGGTGGTCAGTTTGCCCCACGGCTATGGGTTGGACTATCCCGATGCGAATGGAACGCGCACCCGCTAC
GGCCCGCTCTTGAATTTGTTGACCGACGCCCAACATTGCGACACCATCAGTGCCACCCCTTTCCATAAAAATGTACCTGT
GAGATTAAGACCCATAGAGATGGCGAGGGCAGCAAGCTTGCACGAAAGTTTGCCGTGA

Upstream 100 bases:

>100_bases
ATCTGTCTCGGTGACCAAAGAAGAGGTTTATCACAGGGCATTGGATTGCAACCCAAAGGCCCCTATGCTGACAGTAGTTC
CCCTCTACTCGACCTGAATC

Downstream 100 bases:

>100_bases
ATTAGCTCTAGAGTATTGACTTATCAGTTTTTTTATAGATTATCTTGGATCCCTTTTTTGTCTGAATTTCTAGATTTTGT
TACAGGGATTTTATCGAGTG

Product: molybdopterin oxidoreductase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 765; Mature: 764

Protein sequence:

>765_residues
MTDWQPTACILCSRNCGLQVQVADGHLTKIRGDKNHPVSAGYICQKAAQLDHYQNNADRLTQPLKRQEDGSYQPIDWQTA
ITEIAARLLDLKQTYGKECLAFYGGGGQGNHLGSMYSSTFRDALEIPYYYSALAQEKTGDFWANGKLFGRQNCHTTEDIE
QTECVLFIGTNPWQAHGIRNARPTLKQIAQDDQRTMIVIDPRRTETAELADIHLQLRPGTDAFLLSAMLAILVQEGWEDQ
AFLQEHTIGYTEVRACLLTIPIADHIERAGVDADQVYEAVRRFATAKSANVRVDLGLQQSLNSTLNSYLEKLFFLLTGNL
GKPGGNNFHTFFLPWVGHSDAEAKTLCQTKATGITEIAQLFPPNVLPAEIESDHPQRIRGLIVDSANPVVSGADTQAYQR
AFPKLDLLVVVDVAMTETARYADYILSAASQFEKWEAAFFNLEFPTNAFHLRKPLFAPLADTLPESEIYRRLAVAIGAIP
ERYPVLEQVARWHGRWPQLGLYRVALVAAMALQPQLRRTVAFALQGSLGKTLPDDSIAPFWGVSQLYVQHHGEAVARTGL
PGRGGRLAEALFQRILHGHSGAPISQHRYEETWALMGYKDQKVRLVISELIEELQTLSSHHAWPEYPLMLIAGERRMYNA
NTIYRNPQWRQNDAEGVLKIHPVDAKALALAEGSHAVCESPWGQLTVQVKLCDTLRPGVVSLPHGYGLDYPDANGTRTRY
GPLLNLLTDAQHCDTISATPFHKNVPVRLRPIEMARAASLHESLP

Sequences:

>Translated_765_residues
MTDWQPTACILCSRNCGLQVQVADGHLTKIRGDKNHPVSAGYICQKAAQLDHYQNNADRLTQPLKRQEDGSYQPIDWQTA
ITEIAARLLDLKQTYGKECLAFYGGGGQGNHLGSMYSSTFRDALEIPYYYSALAQEKTGDFWANGKLFGRQNCHTTEDIE
QTECVLFIGTNPWQAHGIRNARPTLKQIAQDDQRTMIVIDPRRTETAELADIHLQLRPGTDAFLLSAMLAILVQEGWEDQ
AFLQEHTIGYTEVRACLLTIPIADHIERAGVDADQVYEAVRRFATAKSANVRVDLGLQQSLNSTLNSYLEKLFFLLTGNL
GKPGGNNFHTFFLPWVGHSDAEAKTLCQTKATGITEIAQLFPPNVLPAEIESDHPQRIRGLIVDSANPVVSGADTQAYQR
AFPKLDLLVVVDVAMTETARYADYILSAASQFEKWEAAFFNLEFPTNAFHLRKPLFAPLADTLPESEIYRRLAVAIGAIP
ERYPVLEQVARWHGRWPQLGLYRVALVAAMALQPQLRRTVAFALQGSLGKTLPDDSIAPFWGVSQLYVQHHGEAVARTGL
PGRGGRLAEALFQRILHGHSGAPISQHRYEETWALMGYKDQKVRLVISELIEELQTLSSHHAWPEYPLMLIAGERRMYNA
NTIYRNPQWRQNDAEGVLKIHPVDAKALALAEGSHAVCESPWGQLTVQVKLCDTLRPGVVSLPHGYGLDYPDANGTRTRY
GPLLNLLTDAQHCDTISATPFHKNVPVRLRPIEMARAASLHESLP
>Mature_764_residues
TDWQPTACILCSRNCGLQVQVADGHLTKIRGDKNHPVSAGYICQKAAQLDHYQNNADRLTQPLKRQEDGSYQPIDWQTAI
TEIAARLLDLKQTYGKECLAFYGGGGQGNHLGSMYSSTFRDALEIPYYYSALAQEKTGDFWANGKLFGRQNCHTTEDIEQ
TECVLFIGTNPWQAHGIRNARPTLKQIAQDDQRTMIVIDPRRTETAELADIHLQLRPGTDAFLLSAMLAILVQEGWEDQA
FLQEHTIGYTEVRACLLTIPIADHIERAGVDADQVYEAVRRFATAKSANVRVDLGLQQSLNSTLNSYLEKLFFLLTGNLG
KPGGNNFHTFFLPWVGHSDAEAKTLCQTKATGITEIAQLFPPNVLPAEIESDHPQRIRGLIVDSANPVVSGADTQAYQRA
FPKLDLLVVVDVAMTETARYADYILSAASQFEKWEAAFFNLEFPTNAFHLRKPLFAPLADTLPESEIYRRLAVAIGAIPE
RYPVLEQVARWHGRWPQLGLYRVALVAAMALQPQLRRTVAFALQGSLGKTLPDDSIAPFWGVSQLYVQHHGEAVARTGLP
GRGGRLAEALFQRILHGHSGAPISQHRYEETWALMGYKDQKVRLVISELIEELQTLSSHHAWPEYPLMLIAGERRMYNAN
TIYRNPQWRQNDAEGVLKIHPVDAKALALAEGSHAVCESPWGQLTVQVKLCDTLRPGVVSLPHGYGLDYPDANGTRTRYG
PLLNLLTDAQHCDTISATPFHKNVPVRLRPIEMARAASLHESLP

Specific function: Catalyzes the oxidation of formate [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI3868721, Length=459, Percent_Identity=27.2331154684096, Blast_Score=139, Evalue=6e-34,
Organism=Escherichia coli, GI87081797, Length=545, Percent_Identity=24.7706422018349, Blast_Score=121, Evalue=2e-28,
Organism=Escherichia coli, GI1787870, Length=472, Percent_Identity=25.635593220339, Blast_Score=116, Evalue=5e-27,
Organism=Escherichia coli, GI171474008, Length=354, Percent_Identity=27.683615819209, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1788534, Length=806, Percent_Identity=23.2009925558313, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1787778, Length=514, Percent_Identity=26.4591439688716, Blast_Score=95, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006478
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.2.1.2 [H]

Molecular weight: Translated: 85288; Mature: 85157

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDWQPTACILCSRNCGLQVQVADGHLTKIRGDKNHPVSAGYICQKAAQLDHYQNNADRL
CCCCCCCEEEEEECCCCEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCHHHH
TQPLKRQEDGSYQPIDWQTAITEIAARLLDLKQTYGKECLAFYGGGGQGNHLGSMYSSTF
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHH
RDALEIPYYYSALAQEKTGDFWANGKLFGRQNCHTTEDIEQTECVLFIGTNPWQAHGIRN
HHHHCCCHHHHHHHHHCCCCEEECCEEECCCCCCCCCCCCCCCEEEEEECCCHHHCCCCC
ARPTLKQIAQDDQRTMIVIDPRRTETAELADIHLQLRPGTDAFLLSAMLAILVQEGWEDQ
CCHHHHHHHCCCCCEEEEECCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCH
AFLQEHTIGYTEVRACLLTIPIADHIERAGVDADQVYEAVRRFATAKSANVRVDLGLQQS
HHHHHHCCCHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEECHHHH
LNSTLNSYLEKLFFLLTGNLGKPGGNNFHTFFLPWVGHSDAEAKTLCQTKATGITEIAQL
HHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHCCCHHHHHHH
FPPNVLPAEIESDHPQRIRGLIVDSANPVVSGADTQAYQRAFPKLDLLVVVDVAMTETAR
CCCCCCCCCCCCCCHHHHHEEEEECCCCCCCCCCHHHHHHHCCCCEEEEEEEHHHHHHHH
YADYILSAASQFEKWEAAFFNLEFPTNAFHLRKPLFAPLADTLPESEIYRRLAVAIGAIP
HHHHHHHHHHHHHHHHHEEEEEECCCCHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHCCC
ERYPVLEQVARWHGRWPQLGLYRVALVAAMALQPQLRRTVAFALQGSLGKTLPDDSIAPF
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCC
WGVSQLYVQHHGEAVARTGLPGRGGRLAEALFQRILHGHSGAPISQHRYEETWALMGYKD
CCHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCC
QKVRLVISELIEELQTLSSHHAWPEYPLMLIAGERRMYNANTIYRNPQWRQNDAEGVLKI
CHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEECCCEEECCCCCCCCCCCCEEEE
HPVDAKALALAEGSHAVCESPWGQLTVQVKLCDTLRPGVVSLPHGYGLDYPDANGTRTRY
ECCCCHHEEEECCCCHHHCCCCCCEEEEEEEECCCCCCCEECCCCCCCCCCCCCCCCCHH
GPLLNLLTDAQHCDTISATPFHKNVPVRLRPIEMARAASLHESLP
HHHHHHHHCHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TDWQPTACILCSRNCGLQVQVADGHLTKIRGDKNHPVSAGYICQKAAQLDHYQNNADRL
CCCCCCEEEEEECCCCEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCHHHH
TQPLKRQEDGSYQPIDWQTAITEIAARLLDLKQTYGKECLAFYGGGGQGNHLGSMYSSTF
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHH
RDALEIPYYYSALAQEKTGDFWANGKLFGRQNCHTTEDIEQTECVLFIGTNPWQAHGIRN
HHHHCCCHHHHHHHHHCCCCEEECCEEECCCCCCCCCCCCCCCEEEEEECCCHHHCCCCC
ARPTLKQIAQDDQRTMIVIDPRRTETAELADIHLQLRPGTDAFLLSAMLAILVQEGWEDQ
CCHHHHHHHCCCCCEEEEECCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCH
AFLQEHTIGYTEVRACLLTIPIADHIERAGVDADQVYEAVRRFATAKSANVRVDLGLQQS
HHHHHHCCCHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEECHHHH
LNSTLNSYLEKLFFLLTGNLGKPGGNNFHTFFLPWVGHSDAEAKTLCQTKATGITEIAQL
HHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHCCCHHHHHHH
FPPNVLPAEIESDHPQRIRGLIVDSANPVVSGADTQAYQRAFPKLDLLVVVDVAMTETAR
CCCCCCCCCCCCCCHHHHHEEEEECCCCCCCCCCHHHHHHHCCCCEEEEEEEHHHHHHHH
YADYILSAASQFEKWEAAFFNLEFPTNAFHLRKPLFAPLADTLPESEIYRRLAVAIGAIP
HHHHHHHHHHHHHHHHHEEEEEECCCCHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHCCC
ERYPVLEQVARWHGRWPQLGLYRVALVAAMALQPQLRRTVAFALQGSLGKTLPDDSIAPF
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCC
WGVSQLYVQHHGEAVARTGLPGRGGRLAEALFQRILHGHSGAPISQHRYEETWALMGYKD
CCHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCC
QKVRLVISELIEELQTLSSHHAWPEYPLMLIAGERRMYNANTIYRNPQWRQNDAEGVLKI
CHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEECCCEEECCCCCCCCCCCCEEEE
HPVDAKALALAEGSHAVCESPWGQLTVQVKLCDTLRPGVVSLPHGYGLDYPDANGTRTRY
ECCCCHHEEEECCCCHHHCCCCCCEEEEEEEECCCCCCCEECCCCCCCCCCCCCCCCCHH
GPLLNLLTDAQHCDTISATPFHKNVPVRLRPIEMARAASLHESLP
HHHHHHHHCHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]