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The map label for this gene is cph2 [H]

Identifier: 158334794

GI number: 158334794

Start: 1596554

End: 1597735

Strand: Direct

Name: cph2 [H]

Synonym: AM1_1629

Alternate gene names: 158334794

Gene position: 1596554-1597735 (Clockwise)

Preceding gene: 158334793

Following gene: 158334798

Centisome position: 24.55

GC content: 44.67

Gene sequence:

>1182_bases
ATGCATTATCATTCTGGCATTCGACCAGCGGCCCGACAGTCCTGGATAAAGCAGTGGCAACTCGTTTTATTCCCCGGAAT
TATGCTGATCCTACTGATCGGAATTGTTGCTGGTGGACAATCATTACGGCAACAAATTGAAACGCAAGACAAGTCCCTAG
AACTTAACTTAGTCAGAGGCGTTCATGATTTTAATCAACTCCAGAGGGAAGTGAATCGTCTACGACTTCAGCTGACCCGT
AACCCTACTACCAGTACCAAGAACTTAAATCTACAGCTGAAGATTACGCAAAGCCGATTCACGATTATTCAACGGCACTC
TCTAGCTCGCAACTTAAATACTCAAGTTGCCACCATTAAAGATCATTTAATTCAATCTTGGTTGTCGTTAAAACCTGAGA
TCCAACGCTGGCAGCTAGACCCCAGCAATACTAAGCTCAAAACTCAAATTATTGACCAGCTTGACAACCTAGAACTCGAT
ATCAATCAAGTTTCTCTTCTCCACCAACGCCAACAGTGGAAGCAATATCAAAGTCGAATCCGACGTCATTCCCATTCGCT
ACAGCTATTGAGCATCATCACCATTTTGTTTTGTGGTTTTACCTTGCTGGTTGGTTACCTACTGATGCAATTTGTGCGTG
CTCGTCAGCGCTTATTAGAAAAAGTAGAACAGTTGGCCACCATTGATGATGTTACGCAAATTGCCAATCGACGCCATTTT
AATGCCGTTTTTGCCCAAGAGTGGCAAAGAATGCTCCGGGAACAATCTTGCTTATCTCTACTCCTGTGTGACGTTGATTG
CTTTAAGGCCTACAACGATCATTATGGTCATCAAGCAGGGGATAGTTGCTTGTTTCAAATTGCCCAAACCATTCATAACT
GTATGCGCAGACCCAGTGATTTTGCAGCTCGATATGGTGGCGAAGAATTTGTGATTATCCTGCCTCATACCCAGCTGTCT
GGGGCTCAAGCTCAAGCTCAGGTTATCCAAGAGAACCTACAAAAGCTAGCCTTGGCCCATGCTGAATCCAGCATCAGTGA
CTATGTCACTATCAGTATTGGCATTGCCAGTGGGATTCCACAACTAGAGCTGAATGCCCATCAGATCATCGAACAGGCAG
ATAAAGCACTGTACCAAGCCAAAGCTCAGGGCCGTAACCGTTCCTGCTTCAGTGAGTTCTAA

Upstream 100 bases:

>100_bases
TGCTGGTATTTCCATATCAACACTTCCCATCCGTATCGGAATTTGCAGAAGAATCCTACTGGATCTGGCAAATCGCAGAA
ATTAATGTTCAGTAATAGCA

Downstream 100 bases:

>100_bases
AGAATCTGTGCCTTATCTGTTATTCTTCAGCTCACGGGCATCCCTAAAATATCTTCAATTTTAGGTAACTCCTCCAAAGG
AATCACGCGACCTTCATCAA

Product: diguanylate cyclase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MHYHSGIRPAARQSWIKQWQLVLFPGIMLILLIGIVAGGQSLRQQIETQDKSLELNLVRGVHDFNQLQREVNRLRLQLTR
NPTTSTKNLNLQLKITQSRFTIIQRHSLARNLNTQVATIKDHLIQSWLSLKPEIQRWQLDPSNTKLKTQIIDQLDNLELD
INQVSLLHQRQQWKQYQSRIRRHSHSLQLLSIITILFCGFTLLVGYLLMQFVRARQRLLEKVEQLATIDDVTQIANRRHF
NAVFAQEWQRMLREQSCLSLLLCDVDCFKAYNDHYGHQAGDSCLFQIAQTIHNCMRRPSDFAARYGGEEFVIILPHTQLS
GAQAQAQVIQENLQKLALAHAESSISDYVTISIGIASGIPQLELNAHQIIEQADKALYQAKAQGRNRSCFSEF

Sequences:

>Translated_393_residues
MHYHSGIRPAARQSWIKQWQLVLFPGIMLILLIGIVAGGQSLRQQIETQDKSLELNLVRGVHDFNQLQREVNRLRLQLTR
NPTTSTKNLNLQLKITQSRFTIIQRHSLARNLNTQVATIKDHLIQSWLSLKPEIQRWQLDPSNTKLKTQIIDQLDNLELD
INQVSLLHQRQQWKQYQSRIRRHSHSLQLLSIITILFCGFTLLVGYLLMQFVRARQRLLEKVEQLATIDDVTQIANRRHF
NAVFAQEWQRMLREQSCLSLLLCDVDCFKAYNDHYGHQAGDSCLFQIAQTIHNCMRRPSDFAARYGGEEFVIILPHTQLS
GAQAQAQVIQENLQKLALAHAESSISDYVTISIGIASGIPQLELNAHQIIEQADKALYQAKAQGRNRSCFSEF
>Mature_393_residues
MHYHSGIRPAARQSWIKQWQLVLFPGIMLILLIGIVAGGQSLRQQIETQDKSLELNLVRGVHDFNQLQREVNRLRLQLTR
NPTTSTKNLNLQLKITQSRFTIIQRHSLARNLNTQVATIKDHLIQSWLSLKPEIQRWQLDPSNTKLKTQIIDQLDNLELD
INQVSLLHQRQQWKQYQSRIRRHSHSLQLLSIITILFCGFTLLVGYLLMQFVRARQRLLEKVEQLATIDDVTQIANRRHF
NAVFAQEWQRMLREQSCLSLLLCDVDCFKAYNDHYGHQAGDSCLFQIAQTIHNCMRRPSDFAARYGGEEFVIILPHTQLS
GAQAQAQVIQENLQKLALAHAESSISDYVTISIGIASGIPQLELNAHQIIEQADKALYQAKAQGRNRSCFSEF

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG3706

COG function: function code T; Response regulator containing a CheY-like receiver domain and a GGDEF domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI87081881, Length=176, Percent_Identity=36.3636363636364, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI145693134, Length=194, Percent_Identity=32.9896907216495, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786584, Length=199, Percent_Identity=30.6532663316583, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1787262, Length=172, Percent_Identity=36.046511627907, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87082007, Length=208, Percent_Identity=33.1730769230769, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787802, Length=192, Percent_Identity=28.6458333333333, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1788381, Length=195, Percent_Identity=31.7948717948718, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1787816, Length=165, Percent_Identity=32.1212121212121, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI87081974, Length=211, Percent_Identity=30.3317535545024, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788085, Length=167, Percent_Identity=32.3353293413174, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787541, Length=174, Percent_Identity=31.0344827586207, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 45299; Mature: 45299

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCHHHHHHHHHHHHHHHHHCCCCCCHHCCC
>Mature Secondary Structure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CCCCCHHHHHHHHHHHHHHHHHCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]