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The map label for this gene is crtI [H]

Identifier: 158334644

GI number: 158334644

Start: 1461171

End: 1462709

Strand: Reverse

Name: crtI [H]

Synonym: AM1_1474

Alternate gene names: 158334644

Gene position: 1462709-1461171 (Counterclockwise)

Preceding gene: 158334645

Following gene: 158334637

Centisome position: 22.49

GC content: 54.13

Gene sequence:

>1539_bases
ATGGCAGATTATGACGTCCTCGTGATTGGTAGCGGCATCGGAGGACTGATCGCTGGCAGTTTGTTGGCCCGATACGGTAA
ACGTGTACTCATCTGTGAGAGCCATGCAATTCCAGGTGGGGCAGCCCATGGGTTTCAGCGCCAAGGTTTTCATTTTGATA
CTGGCCCCTCCTTTTATTGTGGTCTCAGTGACCCTCACAGCCTGAATCCAGTTCGCCAAGTCTTGCAGGTTTTAGGCGAA
ACCGTCGATGCGATCGCATATGACCCTCTTGGCTACTATCACTTCCCCGCAGACGACCCGGCTGGGCATTTAGCAAGGGG
CTTCCCCATCTATGGAGATGCCCAAAAGTACCGAGACGCCGTCGCTCAAATTACCCCTGACGGTGCTCGTCAGCTCCAGA
AACTGGAACAAGATTTTCTGGCCCTATTTGCCCCGCTGAAACAAATTCCTCTCCTCACCCTCCGCAGCAATTGGACCTTG
ATTCCCTGGCTGATCCGGCATCAGCCTATGGCTTTAGCCCAGCTATTGCCCCAGCTCCGCAATATTCAGAGTTCTGCTGG
AGCCATGCTCGATCGCACCGTGAGGGATCCTTGGGTGCGTCGCTTGTTCGATTTGGAATGCTTTCTACTCTCAGGGCTTA
CAGCCCAAGACACCGTTGCCCCGGAAATGGCGTTTATGTTTGGGGAACGGTCTGGTTCCACCATTGATTATCCCGTCGGC
GGCAGTCCTGCCATAATCCAAGCCCTGATTCGAGGTTTAAAGAAGTGGGGGGGAGACCTGCGCCTCAAGGCCCATGTGGA
CCAAATCCTCGTGAAAGGTGGAAAAGTTCAGGGGATTCAGCTTAAGAATGGGGAACGCTTAACGGCCCCCATTGTCATTT
CCAATGCTACGGTCTGGGACACCTTCAATCAGCTTCTCAAACCGGAGGATGTACCGCCGGCCTATCGACGACGATCCTTA
GCTACCCCTGCGGTTGATAGCTTTATGCACCTCCATGTGGGCATCTGCTCTGATGGACTGTCGGACCTCCCAGGACATCA
TGTGGTCATCCATAGCAACCAGCAGCCCATCATTCATCCTGGTAATACCTGCATGGTGTCGATTCCCTCAGTTTGGGATG
CGTCCCTCGCCCCCGAAGGACATCATGTTATTCATACCTATACCCTGGAACCCTTTGCCCCCTGGGAGCAGGTGGTGGAT
TATGAACAGTTGAAGCAGGAGCGGGCCCAGTCACTCTATCGAGCCTTAGAAACCGTGATACCGGATGTGCGATCGCGCAT
CACTCTAGAACTCATCGGCACCCCCCTCACCCATCGTCATTATCTCCGCCGCCATCGAGGCACCTATGGTCCTGCTATTG
CTGCTGGCAATGGAACCTTCCCTAGTTGCCATACCCCTATATCGGGCCTGTATCGAGTGGGGGATTCAACCATGCCTGGC
ATTGGTGTACCCGCAGTGGCTGCTTCCGGTATCCTCTGCGCCAATACCCTAGTCTCCCCACAGCAGATTCAGGATTTACT
ACAAACACTAGTGCCGTAA

Upstream 100 bases:

>100_bases
GAAAGCCCTAATATTAGAGTCTCGATTGGCAAAGGATTCACACCTTAACTGATCCTAGCGTTAACATTTCATTAGATACG
CAAAAGGCCCTAAAGCATCA

Downstream 100 bases:

>100_bases
AGCATCAGTCTTGTTTTACCGTGCTTGGCCTTTGACAATAACCGTTTGATCCTGAAAATTCAGATCTTTAATTTGGAGCT
GTCCCAACTGAAGATTAACA

Product: carotenoid isomerase

Products: NA

Alternate protein names: Phytoene desaturase [H]

Number of amino acids: Translated: 512; Mature: 511

Protein sequence:

>512_residues
MADYDVLVIGSGIGGLIAGSLLARYGKRVLICESHAIPGGAAHGFQRQGFHFDTGPSFYCGLSDPHSLNPVRQVLQVLGE
TVDAIAYDPLGYYHFPADDPAGHLARGFPIYGDAQKYRDAVAQITPDGARQLQKLEQDFLALFAPLKQIPLLTLRSNWTL
IPWLIRHQPMALAQLLPQLRNIQSSAGAMLDRTVRDPWVRRLFDLECFLLSGLTAQDTVAPEMAFMFGERSGSTIDYPVG
GSPAIIQALIRGLKKWGGDLRLKAHVDQILVKGGKVQGIQLKNGERLTAPIVISNATVWDTFNQLLKPEDVPPAYRRRSL
ATPAVDSFMHLHVGICSDGLSDLPGHHVVIHSNQQPIIHPGNTCMVSIPSVWDASLAPEGHHVIHTYTLEPFAPWEQVVD
YEQLKQERAQSLYRALETVIPDVRSRITLELIGTPLTHRHYLRRHRGTYGPAIAAGNGTFPSCHTPISGLYRVGDSTMPG
IGVPAVAASGILCANTLVSPQQIQDLLQTLVP

Sequences:

>Translated_512_residues
MADYDVLVIGSGIGGLIAGSLLARYGKRVLICESHAIPGGAAHGFQRQGFHFDTGPSFYCGLSDPHSLNPVRQVLQVLGE
TVDAIAYDPLGYYHFPADDPAGHLARGFPIYGDAQKYRDAVAQITPDGARQLQKLEQDFLALFAPLKQIPLLTLRSNWTL
IPWLIRHQPMALAQLLPQLRNIQSSAGAMLDRTVRDPWVRRLFDLECFLLSGLTAQDTVAPEMAFMFGERSGSTIDYPVG
GSPAIIQALIRGLKKWGGDLRLKAHVDQILVKGGKVQGIQLKNGERLTAPIVISNATVWDTFNQLLKPEDVPPAYRRRSL
ATPAVDSFMHLHVGICSDGLSDLPGHHVVIHSNQQPIIHPGNTCMVSIPSVWDASLAPEGHHVIHTYTLEPFAPWEQVVD
YEQLKQERAQSLYRALETVIPDVRSRITLELIGTPLTHRHYLRRHRGTYGPAIAAGNGTFPSCHTPISGLYRVGDSTMPG
IGVPAVAASGILCANTLVSPQQIQDLLQTLVP
>Mature_511_residues
ADYDVLVIGSGIGGLIAGSLLARYGKRVLICESHAIPGGAAHGFQRQGFHFDTGPSFYCGLSDPHSLNPVRQVLQVLGET
VDAIAYDPLGYYHFPADDPAGHLARGFPIYGDAQKYRDAVAQITPDGARQLQKLEQDFLALFAPLKQIPLLTLRSNWTLI
PWLIRHQPMALAQLLPQLRNIQSSAGAMLDRTVRDPWVRRLFDLECFLLSGLTAQDTVAPEMAFMFGERSGSTIDYPVGG
SPAIIQALIRGLKKWGGDLRLKAHVDQILVKGGKVQGIQLKNGERLTAPIVISNATVWDTFNQLLKPEDVPPAYRRRSLA
TPAVDSFMHLHVGICSDGLSDLPGHHVVIHSNQQPIIHPGNTCMVSIPSVWDASLAPEGHHVIHTYTLEPFAPWEQVVDY
EQLKQERAQSLYRALETVIPDVRSRITLELIGTPLTHRHYLRRHRGTYGPAIAAGNGTFPSCHTPISGLYRVGDSTMPGI
GVPAVAASGILCANTLVSPQQIQDLLQTLVP

Specific function: This enzyme converts phytoene into zeta-carotene via the intermediary of phytofluene by the symmetrical introduction of two double bonds at the C-11 and C-11' positions of phytoene [H]

COG id: COG1233

COG function: function code Q; Phytoene dehydrogenase and related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carotenoid/retinoid oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI203098013, Length=559, Percent_Identity=24.3291592128801, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17540238, Length=560, Percent_Identity=22.5, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002937
- InterPro:   IPR008150
- InterPro:   IPR014105 [H]

Pfam domain/function: PF01593 Amino_oxidase [H]

EC number: NA

Molecular weight: Translated: 56010; Mature: 55879

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADYDVLVIGSGIGGLIAGSLLARYGKRVLICESHAIPGGAAHGFQRQGFHFDTGPSFYC
CCCCEEEEEECCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEE
GLSDPHSLNPVRQVLQVLGETVDAIAYDPLGYYHFPADDPAGHLARGFPIYGDAQKYRDA
CCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCEECCCCCCCCHHHCCCCCCCCHHHHHHH
VAQITPDGARQLQKLEQDFLALFAPLKQIPLLTLRSNWTLIPWLIRHQPMALAQLLPQLR
HHHCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEHHHHHCCCHHHHHHHHHHH
NIQSSAGAMLDRTVRDPWVRRLFDLECFLLSGLTAQDTVAPEMAFMFGERSGSTIDYPVG
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHCHHHHHHHCCCCCCEEECCCC
GSPAIIQALIRGLKKWGGDLRLKAHVDQILVKGGKVQGIQLKNGERLTAPIVISNATVWD
CCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCEEEEEECCCCEEEEEEEEECCHHHH
TFNQLLKPEDVPPAYRRRSLATPAVDSFMHLHVGICSDGLSDLPGHHVVIHSNQQPIIHP
HHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHCCCCEEEEECCCCCEEEC
GNTCMVSIPSVWDASLAPEGHHVIHTYTLEPFAPWEQVVDYEQLKQERAQSLYRALETVI
CCEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHH
PDVRSRITLELIGTPLTHRHYLRRHRGTYGPAIAAGNGTFPSCHTPISGLYRVGDSTMPG
HHHHHEEEEEEECCCHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCHHHHHHCCCCCCCC
IGVPAVAASGILCANTLVSPQQIQDLLQTLVP
CCCHHHHHCCHHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
ADYDVLVIGSGIGGLIAGSLLARYGKRVLICESHAIPGGAAHGFQRQGFHFDTGPSFYC
CCCEEEEEECCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEE
GLSDPHSLNPVRQVLQVLGETVDAIAYDPLGYYHFPADDPAGHLARGFPIYGDAQKYRDA
CCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCEECCCCCCCCHHHCCCCCCCCHHHHHHH
VAQITPDGARQLQKLEQDFLALFAPLKQIPLLTLRSNWTLIPWLIRHQPMALAQLLPQLR
HHHCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEHHHHHCCCHHHHHHHHHHH
NIQSSAGAMLDRTVRDPWVRRLFDLECFLLSGLTAQDTVAPEMAFMFGERSGSTIDYPVG
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHCHHHHHHHCCCCCCEEECCCC
GSPAIIQALIRGLKKWGGDLRLKAHVDQILVKGGKVQGIQLKNGERLTAPIVISNATVWD
CCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCEEEEEECCCCEEEEEEEEECCHHHH
TFNQLLKPEDVPPAYRRRSLATPAVDSFMHLHVGICSDGLSDLPGHHVVIHSNQQPIIHP
HHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHCCCCEEEEECCCCCEEEC
GNTCMVSIPSVWDASLAPEGHHVIHTYTLEPFAPWEQVVDYEQLKQERAQSLYRALETVI
CCEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHH
PDVRSRITLELIGTPLTHRHYLRRHRGTYGPAIAAGNGTFPSCHTPISGLYRVGDSTMPG
HHHHHEEEEEEECCCHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCHHHHHHCCCCCCCC
IGVPAVAASGILCANTLVSPQQIQDLLQTLVP
CCCHHHHHCCHHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2747617; 2546948; 2144293 [H]