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The map label for this gene is aroG [H]

Identifier: 158334562

GI number: 158334562

Start: 1369067

End: 1370134

Strand: Direct

Name: aroG [H]

Synonym: AM1_1389

Alternate gene names: 158334562

Gene position: 1369067-1370134 (Clockwise)

Preceding gene: 158334561

Following gene: 158334564

Centisome position: 21.05

GC content: 51.4

Gene sequence:

>1068_bases
ATGTATCAGACCGCCGACCTGCATGTCGTTGAAACCCGTCCCTTGATTAGTCCTGCTTTGCTCCATCATGAAGTGCCGTT
GACAGATACAGCGGCTGCCCTCGTCGCAGAGACCCGCGATCGCATCCGCAATATTCTGCGTAACGAAGATCAGCGCCTCT
TAGTCATTGTTGGTCCTTGTTCAGTTCATGATGTCGATGCCGCCTTGGAATATGGCAAAAAGCTAGCGGGTCTACGAGAG
CAGCTCTCTGATCAGCTCGAAATCGTTATGCGAGTGTATTTTGAAAAACCTCGGACCAGCATTGGCTGGAAAGGGCTGAT
TAACGATCCGCACCTAGATGGCAGCTATGACATCAACACCGGCTTGCGCTTAGCCCGTCAACTTCTGCTGGACTTAGCCA
ACCTGGGTTTACCCGCCGCCACCGAACTACTCGATCCGATCACACCTCAATATATTGCCGACTTAATTACCTGGACCGCT
ATTGGCGCTCGCACCACAGAAAGCCAAACCCACCGAGAAATGGCTTCGGGTCTATCCATGCCCATTGGTTTCAAAAATAA
CACCGACGGGAGTTTGCAAGCCGCCAGCAATGCCATGCTAGCAGCGAACCAACCCCATCGTTTTCTAGGCATCAACCACC
ATGGTCTCGCCAGTATTGTCAAAACCACAGGCAACCCTGACACTCATTTGGTCCTTCGAGGCGGCAAACAAGGCCCCAAC
TATGCCGCTGAGAATGTGGAACAGGCCACCAAAGAACTTGCCAAACACAATCTGAATCCCAGAGTCATGGTGGACTGTAG
CCATGCCAACGCCAACAAAGACCATAACCGGCAAGTCGAGGTCCTAGAAAACGTTGCACGACAACTTGACAATGGCTCCC
AACGGCTGTTAGGGGTAATGATTGAAAGTCATTTAGTGGCTGGGAACCAACCCATTTCAGAAGATTTGAGCCAGCTAACC
TATGGACAAAGCATCACGGATGCCTGTGTCAACTTCGAAACAACCACCAAAATGCTAACCACCTTGGCAGCATCGGTTCG
CGGCGCTGACACAGTCTCAGTGAGCTAA

Upstream 100 bases:

>100_bases
AGGCAGGACCCCGTAATTTTGCCGTAAACTGTAAATACGTAAATACGCCCCTGGCCAATCTTCTGTGAGCAAGGCCAGTA
CCTGGAGTTTTTGAGACACC

Downstream 100 bases:

>100_bases
AGACCCACATCTTCTTAAGGTGTCAAAAGTTTCTTCTTTTGCTCAGCGGTCAAAATAGACAGGATACGCTGTTGGGCTAG
GGACTCAACTTCTTGTAACT

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MYQTADLHVVETRPLISPALLHHEVPLTDTAAALVAETRDRIRNILRNEDQRLLVIVGPCSVHDVDAALEYGKKLAGLRE
QLSDQLEIVMRVYFEKPRTSIGWKGLINDPHLDGSYDINTGLRLARQLLLDLANLGLPAATELLDPITPQYIADLITWTA
IGARTTESQTHREMASGLSMPIGFKNNTDGSLQAASNAMLAANQPHRFLGINHHGLASIVKTTGNPDTHLVLRGGKQGPN
YAAENVEQATKELAKHNLNPRVMVDCSHANANKDHNRQVEVLENVARQLDNGSQRLLGVMIESHLVAGNQPISEDLSQLT
YGQSITDACVNFETTTKMLTTLAASVRGADTVSVS

Sequences:

>Translated_355_residues
MYQTADLHVVETRPLISPALLHHEVPLTDTAAALVAETRDRIRNILRNEDQRLLVIVGPCSVHDVDAALEYGKKLAGLRE
QLSDQLEIVMRVYFEKPRTSIGWKGLINDPHLDGSYDINTGLRLARQLLLDLANLGLPAATELLDPITPQYIADLITWTA
IGARTTESQTHREMASGLSMPIGFKNNTDGSLQAASNAMLAANQPHRFLGINHHGLASIVKTTGNPDTHLVLRGGKQGPN
YAAENVEQATKELAKHNLNPRVMVDCSHANANKDHNRQVEVLENVARQLDNGSQRLLGVMIESHLVAGNQPISEDLSQLT
YGQSITDACVNFETTTKMLTTLAASVRGADTVSVS
>Mature_355_residues
MYQTADLHVVETRPLISPALLHHEVPLTDTAAALVAETRDRIRNILRNEDQRLLVIVGPCSVHDVDAALEYGKKLAGLRE
QLSDQLEIVMRVYFEKPRTSIGWKGLINDPHLDGSYDINTGLRLARQLLLDLANLGLPAATELLDPITPQYIADLITWTA
IGARTTESQTHREMASGLSMPIGFKNNTDGSLQAASNAMLAANQPHRFLGINHHGLASIVKTTGNPDTHLVLRGGKQGPN
YAAENVEQATKELAKHNLNPRVMVDCSHANANKDHNRQVEVLENVARQLDNGSQRLLGVMIESHLVAGNQPISEDLSQLT
YGQSITDACVNFETTTKMLTTLAASVRGADTVSVS

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:
GO:0003824: Phospho-2-dehydro-3-deoxyheptonate aldolase
GO:0003849: Phospho-2-dehydro-3-deoxyheptonate aldolase
GO:0008152: Phospho-2-dehydro-3-deoxyheptonate aldolase
GO:0008652: Phospho-2-dehydro-3-deoxyheptonate aldolase
GO:0009058: Phospho-2-dehydro-3-deoxyheptonate aldolase
GO:0009073: Phospho-2-dehydro-3-deoxyheptonate aldolase
GO:0016740: Phospho-2-dehydro-3-deoxyheptonate aldolase

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788953, Length=350, Percent_Identity=52.5714285714286, Blast_Score=403, Evalue=1e-114,
Organism=Escherichia coli, GI1786969, Length=346, Percent_Identity=54.3352601156069, Blast_Score=393, Evalue=1e-110,
Organism=Escherichia coli, GI1787996, Length=346, Percent_Identity=51.1560693641619, Blast_Score=357, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6319726, Length=343, Percent_Identity=49.5626822157434, Blast_Score=347, Evalue=2e-96,
Organism=Saccharomyces cerevisiae, GI6320240, Length=348, Percent_Identity=47.7011494252874, Blast_Score=340, Evalue=2e-94,

Paralogues:

None

Copy number: 2,200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 38729; Mature: 38729

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQTADLHVVETRPLISPALLHHEVPLTDTAAALVAETRDRIRNILRNEDQRLLVIVGPC
CCCCCCEEEEECCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
SVHDVDAALEYGKKLAGLREQLSDQLEIVMRVYFEKPRTSIGWKGLINDPHLDGSYDINT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHH
GLRLARQLLLDLANLGLPAATELLDPITPQYIADLITWTAIGARTTESQTHREMASGLSM
HHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCC
PIGFKNNTDGSLQAASNAMLAANQPHRFLGINHHGLASIVKTTGNPDTHLVLRGGKQGPN
CCCCCCCCCCCHHHHCCCEEECCCCCCEECCCCHHHHHHHHCCCCCCEEEEEECCCCCCC
YAAENVEQATKELAKHNLNPRVMVDCSHANANKDHNRQVEVLENVARQLDNGSQRLLGVM
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
IESHLVAGNQPISEDLSQLTYGQSITDACVNFETTTKMLTTLAASVRGADTVSVS
HHHHHHCCCCCHHHHHHHHHCCCHHHHHHHCHHHHHHHHHHHHHHHCCCCEECCC
>Mature Secondary Structure
MYQTADLHVVETRPLISPALLHHEVPLTDTAAALVAETRDRIRNILRNEDQRLLVIVGPC
CCCCCCEEEEECCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
SVHDVDAALEYGKKLAGLREQLSDQLEIVMRVYFEKPRTSIGWKGLINDPHLDGSYDINT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHH
GLRLARQLLLDLANLGLPAATELLDPITPQYIADLITWTAIGARTTESQTHREMASGLSM
HHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCC
PIGFKNNTDGSLQAASNAMLAANQPHRFLGINHHGLASIVKTTGNPDTHLVLRGGKQGPN
CCCCCCCCCCCHHHHCCCEEECCCCCCEECCCCHHHHHHHHCCCCCCEEEEEECCCCCCC
YAAENVEQATKELAKHNLNPRVMVDCSHANANKDHNRQVEVLENVARQLDNGSQRLLGVM
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
IESHLVAGNQPISEDLSQLTYGQSITDACVNFETTTKMLTTLAASVRGADTVSVS
HHHHHHCCCCCHHHHHHHHHCCCHHHHHHHCHHHHHHHHHHHHHHHCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6146618; 6396419; 9205837; 9278503; 1977738; 6104668; 2857723; 9056491 [H]