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The map label for this gene is frzE [H]

Identifier: 158334552

GI number: 158334552

Start: 1357980

End: 1359800

Strand: Direct

Name: frzE [H]

Synonym: AM1_1379

Alternate gene names: 158334552

Gene position: 1357980-1359800 (Clockwise)

Preceding gene: 158334551

Following gene: 158334554

Centisome position: 20.88

GC content: 48.05

Gene sequence:

>1821_bases
ATGGCTAATGAGACGCCGCTGCGCGATCCTGCTTATCAACTGTTTTTTCAAGAAGCATTAGAACTTTTACTGCAGATTGA
TACGACCTTACAAGAGGTTCTGCAAATTCCGAGTAAAACATCCATTGATTTTTTACTGGAGATGACGCAGATCTTATATG
AGGGAGCCCAATCCCTCAATCTCACTCAGTTAGCCCATCAGGTCCAAGCCTTTTCGAGCTTAATGCTGAATTTACAGCAA
GATCCCTTGGGAACGACACCAGAGGATGCATATCAGTTGAGGCAAGCTTATAAAGAGATGCAAACCGCTTTAGAGGCTTA
TATCTCTGGTCCACCTGTCTTAGATATGTCTTCAAACCTCGATGCTTCTTCAGAACGAGAGTCTGCTTCCCATGGGTCTA
TTGCTTTAGACGTCGCAGAAGATGAGTTAGCCACCAATGGTAATTTAATGCTGCCCGCAGGGGGGAGTGATGTTACCTCT
TTAATCTTGATCTCTGATGTCGCGGAAATTTTGGATCAGCTGCAGCAGGTCTTGGTTAATCCCCAGGTATTTGACCTGGC
GGCCGAGTTAAAAGCCTTGACAGAAGCATTATTGGGTTGGGGAGAAGTTTTAGAGCTCAATGAATTGACCACGATTGCTC
AATCGACCTTAGACATGTTGGACAGCAATCCCCAATCTGCGATTTCGATTGGTCAATTATCTTTGGCTGGCTTTCGAGCC
GCCCATAAAACGGCTTTACAAGCATTGCAGGCTGACTCAGGTTCGCAGAATGCTGACCATCACCCACAAAGCTCGAAGAA
GCTGGATCTTCCATCGAGTCCCACGGCCATGTCTCCCATGGCTGCCGAAATTCCCACTGCTGAGTCATTATCAGCGTCAG
ATGAAGTGATTTTAAATGCCACTCAGCTGTTTGTCTGGCAGCAAGAAAGGCTGCTCTTTACGATTCCATCCGAGGCGGTG
GCAGAAATCCTCATTCCCAGGGCTGAACAGTTAATGGGCAATGAGCATCAGCGTTGTTTAAGTTGGCAGCAGCAGTTTAT
CCCGATTCATCCATTGGGGCATCTGCTCAATCGAGGGGAGTCTCATTGGCCCCGACTCACCGCTGCGGTCTTACCTGGAC
GTGGAGCCAATAGTGCGACGGTATTTGGCAGTTCTCCCTTGATCATTATTCATCAAGGGGGCCAAACCCTGGCCTTAGAA
GTTGAAATCACCCGCTTAGTGACGGAGTCAGAGCTGGTTCTGCAAATTCCGGAAGGACAGATCCATTGTCCTTATTTTTC
TGGCGAGACGGCCTTGGAGTCGGAGCAGTACGGAGTGGTTGATATTGCCGCCCTGCTCAATGAAATGTTGAATTTAAGTC
CCCTGCCAATGCCCAAGGCAGTAAGGCTATCGAGTCCAGCAGTGTCTGTCAGTCCAAAGCCCAAACGCCCTCCCAAAGTT
CCGAAGAAAACGCGATCGCAAACCACAATACTCGTAGTTGACGATTCCAAAATGGTACGCATGATGGTCAGCACGGCGCT
GCAATCCGCTGGTTACGACGTCCTTGAGGCGGCTGATGGTCAATTAGCCATCGAACAGGTAGAGCGGGCAGATATTCAGC
TGATTATTTGTGATGTAGAAATGCCCAATATGAATGGGTTTGAGTTTCTAGAATATCGGTGCCGTCAGCCAGCCATAATG
AACCTACCAGTGGTGATGCTCAGTACATGTAATAGTGACCAGCACCGACAATTAGCAACAACCTTGGGTGCTAACGCTTA
TCTGACAAAACCTTACGATGAATCCAATCTCTTAGCCACCTTACAAGCATTGGTGGGCTAA

Upstream 100 bases:

>100_bases
CATCCTTTGCTTTGTCTTGTCTTCAGTCCCATCTTATTTATGTTGGGACTCTCCCCTCTAATCTGCCAATCAGTTCATGA
CCTATACAAGGAAGCCAGAC

Downstream 100 bases:

>100_bases
CAGCATTCGCCATTCTCTTCGGAGAATCGTTTGGTGTTCGGGGATAGATTCAGACTAGACGCTAGACAGACTCTATTTCA
TGCTCGCCCAAATGAATGCG

Product: chemotaxis response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 606; Mature: 605

Protein sequence:

>606_residues
MANETPLRDPAYQLFFQEALELLLQIDTTLQEVLQIPSKTSIDFLLEMTQILYEGAQSLNLTQLAHQVQAFSSLMLNLQQ
DPLGTTPEDAYQLRQAYKEMQTALEAYISGPPVLDMSSNLDASSERESASHGSIALDVAEDELATNGNLMLPAGGSDVTS
LILISDVAEILDQLQQVLVNPQVFDLAAELKALTEALLGWGEVLELNELTTIAQSTLDMLDSNPQSAISIGQLSLAGFRA
AHKTALQALQADSGSQNADHHPQSSKKLDLPSSPTAMSPMAAEIPTAESLSASDEVILNATQLFVWQQERLLFTIPSEAV
AEILIPRAEQLMGNEHQRCLSWQQQFIPIHPLGHLLNRGESHWPRLTAAVLPGRGANSATVFGSSPLIIIHQGGQTLALE
VEITRLVTESELVLQIPEGQIHCPYFSGETALESEQYGVVDIAALLNEMLNLSPLPMPKAVRLSSPAVSVSPKPKRPPKV
PKKTRSQTTILVVDDSKMVRMMVSTALQSAGYDVLEAADGQLAIEQVERADIQLIICDVEMPNMNGFEFLEYRCRQPAIM
NLPVVMLSTCNSDQHRQLATTLGANAYLTKPYDESNLLATLQALVG

Sequences:

>Translated_606_residues
MANETPLRDPAYQLFFQEALELLLQIDTTLQEVLQIPSKTSIDFLLEMTQILYEGAQSLNLTQLAHQVQAFSSLMLNLQQ
DPLGTTPEDAYQLRQAYKEMQTALEAYISGPPVLDMSSNLDASSERESASHGSIALDVAEDELATNGNLMLPAGGSDVTS
LILISDVAEILDQLQQVLVNPQVFDLAAELKALTEALLGWGEVLELNELTTIAQSTLDMLDSNPQSAISIGQLSLAGFRA
AHKTALQALQADSGSQNADHHPQSSKKLDLPSSPTAMSPMAAEIPTAESLSASDEVILNATQLFVWQQERLLFTIPSEAV
AEILIPRAEQLMGNEHQRCLSWQQQFIPIHPLGHLLNRGESHWPRLTAAVLPGRGANSATVFGSSPLIIIHQGGQTLALE
VEITRLVTESELVLQIPEGQIHCPYFSGETALESEQYGVVDIAALLNEMLNLSPLPMPKAVRLSSPAVSVSPKPKRPPKV
PKKTRSQTTILVVDDSKMVRMMVSTALQSAGYDVLEAADGQLAIEQVERADIQLIICDVEMPNMNGFEFLEYRCRQPAIM
NLPVVMLSTCNSDQHRQLATTLGANAYLTKPYDESNLLATLQALVG
>Mature_605_residues
ANETPLRDPAYQLFFQEALELLLQIDTTLQEVLQIPSKTSIDFLLEMTQILYEGAQSLNLTQLAHQVQAFSSLMLNLQQD
PLGTTPEDAYQLRQAYKEMQTALEAYISGPPVLDMSSNLDASSERESASHGSIALDVAEDELATNGNLMLPAGGSDVTSL
ILISDVAEILDQLQQVLVNPQVFDLAAELKALTEALLGWGEVLELNELTTIAQSTLDMLDSNPQSAISIGQLSLAGFRAA
HKTALQALQADSGSQNADHHPQSSKKLDLPSSPTAMSPMAAEIPTAESLSASDEVILNATQLFVWQQERLLFTIPSEAVA
EILIPRAEQLMGNEHQRCLSWQQQFIPIHPLGHLLNRGESHWPRLTAAVLPGRGANSATVFGSSPLIIIHQGGQTLALEV
EITRLVTESELVLQIPEGQIHCPYFSGETALESEQYGVVDIAALLNEMLNLSPLPMPKAVRLSSPAVSVSPKPKRPPKVP
KKTRSQTTILVVDDSKMVRMMVSTALQSAGYDVLEAADGQLAIEQVERADIQLIICDVEMPNMNGFEFLEYRCRQPAIMN
LPVVMLSTCNSDQHRQLATTLGANAYLTKPYDESNLLATLQALVG

Specific function: FrzE is involved in a sensory transduction pathway that controls the frequency at which cells reverse their gliding direction. FrzE seems to be capable of autophosphorylating itself on an histidine residue and then to transfer that group to an aspartate r

COG id: COG0784

COG function: function code T; FOG: CheY-like receiver

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=116, Percent_Identity=31.8965517241379, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788713, Length=131, Percent_Identity=33.587786259542, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1790437, Length=120, Percent_Identity=37.5, Blast_Score=66, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR011006
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR005467
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01584 CheW; PF02518 HATPase_c; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 65995; Mature: 65864

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANETPLRDPAYQLFFQEALELLLQIDTTLQEVLQIPSKTSIDFLLEMTQILYEGAQSLN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCC
LTQLAHQVQAFSSLMLNLQQDPLGTTPEDAYQLRQAYKEMQTALEAYISGPPVLDMSSNL
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
DASSERESASHGSIALDVAEDELATNGNLMLPAGGSDVTSLILISDVAEILDQLQQVLVN
CCCCCCCCCCCCCEEEEECHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCC
PQVFDLAAELKALTEALLGWGEVLELNELTTIAQSTLDMLDSNPQSAISIGQLSLAGFRA
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AHKTALQALQADSGSQNADHHPQSSKKLDLPSSPTAMSPMAAEIPTAESLSASDEVILNA
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCEEEEH
TQLFVWQQERLLFTIPSEAVAEILIPRAEQLMGNEHQRCLSWQQQFIPIHPLGHLLNRGE
HHEEEEECCCEEEECCHHHHHHHHHCCHHHHCCCHHHHHHHHHHHCCCCCHHHHHHCCCC
SHWPRLTAAVLPGRGANSATVFGSSPLIIIHQGGQTLALEVEITRLVTESELVLQIPEGQ
CCCCEEEEEECCCCCCCCEEEECCCCEEEEECCCCEEEEEEEEEEHCCCCCEEEECCCCC
IHCPYFSGETALESEQYGVVDIAALLNEMLNLSPLPMPKAVRLSSPAVSVSPKPKRPPKV
EECCEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCCCEECCCCCCCCCCC
PKKTRSQTTILVVDDSKMVRMMVSTALQSAGYDVLEAADGQLAIEQVERADIQLIICDVE
CCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHCCCEEEEEEEEE
MPNMNGFEFLEYRCRQPAIMNLPVVMLSTCNSDQHRQLATTLGANAYLTKPYDESNLLAT
CCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEECCCCCHHHHHH
LQALVG
HHHHHC
>Mature Secondary Structure 
ANETPLRDPAYQLFFQEALELLLQIDTTLQEVLQIPSKTSIDFLLEMTQILYEGAQSLN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCC
LTQLAHQVQAFSSLMLNLQQDPLGTTPEDAYQLRQAYKEMQTALEAYISGPPVLDMSSNL
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
DASSERESASHGSIALDVAEDELATNGNLMLPAGGSDVTSLILISDVAEILDQLQQVLVN
CCCCCCCCCCCCCEEEEECHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCC
PQVFDLAAELKALTEALLGWGEVLELNELTTIAQSTLDMLDSNPQSAISIGQLSLAGFRA
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AHKTALQALQADSGSQNADHHPQSSKKLDLPSSPTAMSPMAAEIPTAESLSASDEVILNA
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCEEEEH
TQLFVWQQERLLFTIPSEAVAEILIPRAEQLMGNEHQRCLSWQQQFIPIHPLGHLLNRGE
HHEEEEECCCEEEECCHHHHHHHHHCCHHHHCCCHHHHHHHHHHHCCCCCHHHHHHCCCC
SHWPRLTAAVLPGRGANSATVFGSSPLIIIHQGGQTLALEVEITRLVTESELVLQIPEGQ
CCCCEEEEEECCCCCCCCEEEECCCCEEEEECCCCEEEEEEEEEEHCCCCCEEEECCCCC
IHCPYFSGETALESEQYGVVDIAALLNEMLNLSPLPMPKAVRLSSPAVSVSPKPKRPPKV
EECCEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCCCEECCCCCCCCCCC
PKKTRSQTTILVVDDSKMVRMMVSTALQSAGYDVLEAADGQLAIEQVERADIQLIICDVE
CCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHCCCEEEEEEEEE
MPNMNGFEFLEYRCRQPAIMNLPVVMLSTCNSDQHRQLATTLGANAYLTKPYDESNLLAT
CCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEECCCCCHHHHHH
LQALVG
HHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2165608; 2123853 [H]