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The map label for this gene is yajO [H]

Identifier: 158334500

GI number: 158334500

Start: 1308303

End: 1309376

Strand: Direct

Name: yajO [H]

Synonym: AM1_1324

Alternate gene names: 158334500

Gene position: 1308303-1309376 (Clockwise)

Preceding gene: 158334498

Following gene: 158334501

Centisome position: 20.12

GC content: 50.37

Gene sequence:

>1074_bases
TTGACTGCGTTAAATCACTATCGCTTGTTGGGGCATTCTGGATTACGGGTCTCCCCCCTTTGTCTAGGGACGATGACCTT
TGGGACTGAATGGGGATGGGGAGCGGATCTAGATACTAGTCGCCAAATTCTGGATACCTATGCGAATCGGGGTGGCAATT
TCATTGATACTGCCAATGCCTATACCAATGGGACCAGCGAGCAATTTTTAGGAGAGCTGTTGCAGGGGCGGCGTGATCGC
TTTGTCCTGGCTACCAAATATTCTCTCAATATGGATTCCACAAACCCCAATGCAGGAGGGAATCATCGCCGCAGTCTGGT
ACGGGCAGTGGAAGGCAGCCTCAAGCGTCTGGCCACCGATTACATTGACCTTTACTGGCTGCATGCTTGGGATTATCGCA
ACGCCATTGAAGAGGTGATGCGGGCGCTAGATGATTTGGTGCGTCAGGGTAAGATCTTGCATATAGGGCTATCGGATACA
CCCTCGTGGATTGTCTCCGAAGGGCATGCCATCTCAAGACTTCGAGGTTGGACCTCTGTATCCGCCATCCAGGTTCACTA
CAATTTGGTGGAGCGTACCTCCGAAGCAGACATGCTTCCGATGGCCCGACAGTATGGAATTACACCCTTAGCTTGGTCGC
CCTTAGCTGGTGGGATCTTGTCTGGCAAGTACAGCCGAGAAGATTTACAAGATACGAGTACTGAAAAAGAGGAGTCTGGC
CGCAAAGGCGTCACCCAAGATATCGGTCAATTGAATGAGCGTAGCTTAGAAATTGTCGATATTGTCAAAGAAATCTCCAC
CGAAATAGGTCGCTCTCCCAGTCAGGTGGCCCTCAATTGGCTCCTGCAGCAACCGAGTCGGCCCATTCCCATCATAGGTG
CCCGTAAGCTGGCGCACCTGGAGGATAACTTGGGTGCCCTGGAGTTCACACTCAGTGACGAACATATTGAGCGTCTATAC
CAAATGAGTGCCTTTGATCTGCCATTTCCCCATAACTTTATTGGTTTGGATATGTATAAAGGTGTGGTGGATGGCGAGAA
CACGATTGAGTCAGGATTTACAGTTTACCCATAG

Upstream 100 bases:

>100_bases
TCTATAATATTGATTTGAATTATATACTGACTCTCGTTAAGCTGTAGTCAAAATGAGCTAGTCACTCAAGTGTGGGAGCT
TGCATGCCATGCATCAGTTT

Downstream 100 bases:

>100_bases
GACTCAATAGCCATGAAACCTAAGCACCACAAACAGGCATTGGTAACAGGGGGCAATCGCGGGATTGGTTTTGAGATCGC
AAAGGGCCTTCTCGCCAAAG

Product: aldo/keto reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MTALNHYRLLGHSGLRVSPLCLGTMTFGTEWGWGADLDTSRQILDTYANRGGNFIDTANAYTNGTSEQFLGELLQGRRDR
FVLATKYSLNMDSTNPNAGGNHRRSLVRAVEGSLKRLATDYIDLYWLHAWDYRNAIEEVMRALDDLVRQGKILHIGLSDT
PSWIVSEGHAISRLRGWTSVSAIQVHYNLVERTSEADMLPMARQYGITPLAWSPLAGGILSGKYSREDLQDTSTEKEESG
RKGVTQDIGQLNERSLEIVDIVKEISTEIGRSPSQVALNWLLQQPSRPIPIIGARKLAHLEDNLGALEFTLSDEHIERLY
QMSAFDLPFPHNFIGLDMYKGVVDGENTIESGFTVYP

Sequences:

>Translated_357_residues
MTALNHYRLLGHSGLRVSPLCLGTMTFGTEWGWGADLDTSRQILDTYANRGGNFIDTANAYTNGTSEQFLGELLQGRRDR
FVLATKYSLNMDSTNPNAGGNHRRSLVRAVEGSLKRLATDYIDLYWLHAWDYRNAIEEVMRALDDLVRQGKILHIGLSDT
PSWIVSEGHAISRLRGWTSVSAIQVHYNLVERTSEADMLPMARQYGITPLAWSPLAGGILSGKYSREDLQDTSTEKEESG
RKGVTQDIGQLNERSLEIVDIVKEISTEIGRSPSQVALNWLLQQPSRPIPIIGARKLAHLEDNLGALEFTLSDEHIERLY
QMSAFDLPFPHNFIGLDMYKGVVDGENTIESGFTVYP
>Mature_356_residues
TALNHYRLLGHSGLRVSPLCLGTMTFGTEWGWGADLDTSRQILDTYANRGGNFIDTANAYTNGTSEQFLGELLQGRRDRF
VLATKYSLNMDSTNPNAGGNHRRSLVRAVEGSLKRLATDYIDLYWLHAWDYRNAIEEVMRALDDLVRQGKILHIGLSDTP
SWIVSEGHAISRLRGWTSVSAIQVHYNLVERTSEADMLPMARQYGITPLAWSPLAGGILSGKYSREDLQDTSTEKEESGR
KGVTQDIGQLNERSLEIVDIVKEISTEIGRSPSQVALNWLLQQPSRPIPIIGARKLAHLEDNLGALEFTLSDEHIERLYQ
MSAFDLPFPHNFIGLDMYKGVVDGENTIESGFTVYP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI223718702, Length=305, Percent_Identity=34.4262295081967, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI27436964, Length=321, Percent_Identity=30.5295950155763, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI27436962, Length=321, Percent_Identity=30.5295950155763, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI4504825, Length=317, Percent_Identity=29.0220820189274, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI27436969, Length=314, Percent_Identity=28.9808917197452, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI27436966, Length=319, Percent_Identity=29.7805642633229, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI41152114, Length=308, Percent_Identity=30.5194805194805, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI41327764, Length=310, Percent_Identity=32.5806451612903, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI27436971, Length=310, Percent_Identity=27.4193548387097, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI223718708, Length=168, Percent_Identity=35.1190476190476, Blast_Score=83, Evalue=4e-16,
Organism=Escherichia coli, GI87081735, Length=338, Percent_Identity=34.6153846153846, Blast_Score=195, Evalue=5e-51,
Organism=Escherichia coli, GI1789375, Length=328, Percent_Identity=31.0975609756098, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1789199, Length=358, Percent_Identity=28.2122905027933, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1788081, Length=313, Percent_Identity=30.6709265175719, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1788070, Length=334, Percent_Identity=27.8443113772455, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI48994888, Length=302, Percent_Identity=25.4966887417219, Blast_Score=76, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6323998, Length=351, Percent_Identity=36.7521367521368, Blast_Score=216, Evalue=4e-57,
Organism=Saccharomyces cerevisiae, GI6319958, Length=305, Percent_Identity=36.3934426229508, Blast_Score=201, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6319951, Length=351, Percent_Identity=33.9031339031339, Blast_Score=198, Evalue=9e-52,
Organism=Saccharomyces cerevisiae, GI6322615, Length=269, Percent_Identity=35.3159851301115, Blast_Score=170, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6325169, Length=332, Percent_Identity=29.8192771084337, Blast_Score=149, Evalue=5e-37,
Organism=Saccharomyces cerevisiae, GI6321052, Length=162, Percent_Identity=41.9753086419753, Blast_Score=118, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6321051, Length=140, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24646155, Length=344, Percent_Identity=27.0348837209302, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24640980, Length=326, Percent_Identity=26.0736196319018, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI45549126, Length=326, Percent_Identity=26.3803680981595, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 39943; Mature: 39812

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALNHYRLLGHSGLRVSPLCLGTMTFGTEWGWGADLDTSRQILDTYANRGGNFIDTANA
CCCCCCCCEECCCCCEECCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCC
YTNGTSEQFLGELLQGRRDRFVLATKYSLNMDSTNPNAGGNHRRSLVRAVEGSLKRLATD
CCCCCHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
YIDLYWLHAWDYRNAIEEVMRALDDLVRQGKILHIGLSDTPSWIVSEGHAISRLRGWTSV
HHHHHEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHCCCCHHHHHCCCCCH
SAIQVHYNLVERTSEADMLPMARQYGITPLAWSPLAGGILSGKYSREDLQDTSTEKEESG
HHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCHHCCCCCHHHHHHCCCHHHHCC
RKGVTQDIGQLNERSLEIVDIVKEISTEIGRSPSQVALNWLLQQPSRPIPIIGARKLAHL
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEECHHHHHHH
EDNLGALEFTLSDEHIERLYQMSAFDLPFPHNFIGLDMYKGVVDGENTIESGFTVYP
HCCCCEEEEEECHHHHHHHHHHHHCCCCCCCCEECHHHHHCCCCCCCHHHCCCEECC
>Mature Secondary Structure 
TALNHYRLLGHSGLRVSPLCLGTMTFGTEWGWGADLDTSRQILDTYANRGGNFIDTANA
CCCCCCCEECCCCCEECCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCC
YTNGTSEQFLGELLQGRRDRFVLATKYSLNMDSTNPNAGGNHRRSLVRAVEGSLKRLATD
CCCCCHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
YIDLYWLHAWDYRNAIEEVMRALDDLVRQGKILHIGLSDTPSWIVSEGHAISRLRGWTSV
HHHHHEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHCCCCHHHHHCCCCCH
SAIQVHYNLVERTSEADMLPMARQYGITPLAWSPLAGGILSGKYSREDLQDTSTEKEESG
HHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCHHCCCCCHHHHHHCCCHHHHCC
RKGVTQDIGQLNERSLEIVDIVKEISTEIGRSPSQVALNWLLQQPSRPIPIIGARKLAHL
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEECHHHHHHH
EDNLGALEFTLSDEHIERLYQMSAFDLPFPHNFIGLDMYKGVVDGENTIESGFTVYP
HCCCCEEEEEECHHHHHHHHHHHHCCCCCCCCEECHHHHHCCCCCCCHHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]