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The map label for this gene is nahR [H]

Identifier: 158334499

GI number: 158334499

Start: 1307283

End: 1308185

Strand: Reverse

Name: nahR [H]

Synonym: AM1_1322

Alternate gene names: 158334499

Gene position: 1308185-1307283 (Counterclockwise)

Preceding gene: 158334509

Following gene: 158334497

Centisome position: 20.11

GC content: 47.07

Gene sequence:

>903_bases
ATGGATTTAAGAGGATTTGATCTTAATTTGCTCGTTGTACTCCACATTTTGTTGAAGGAGAGGAGTGTCTCGAAAACAGC
AGAGCGACTTCAGTTGAGTCAACCAGCAGTAAGCGCAGCCCTCAACCGATTACGAACAGCGCTGAAGGATCCGATTTTGG
TCCGGGACGGCTTGCAGATGGTACCCACACCACGAGCAGAGCAGTTAGTAGAACCGGTGCAAGCAATTGTCTCAGCCATT
GAACAAACCCTGGCTGATCCTCAGCCTTTTGACTACAGTTCCATCAGTCGAACCTTTCGGATCGCTACCAACGACTACGG
TGCATTTGTTCTAGTACCGTTCCTGATGAACCGTATGCAGAAGATTGCCCCCCATTTAACATTCGAAATTTGGGATATTG
CCCTAGATGTGGAAACGGCTCTGCGTGAGGGAGAGATTGACTTAGTCATTGCTGATGCCTGGACCTTGAGAAATTGCAAA
TGCCGCAAAACTCTGTTCTCAGAAACGTTTACTTGCCTAGTGCGACAAAATCATCCTCGGGTTGATACCCAACTCACTAT
GGATGATTACCTGCAAGAAAAACATGCTCTTGTTTCTGCGCGTGGACGAGTGACAGGCAATGTAGATATTGCGCTGTCGC
AGCAAAATAAGCAACGGCAAGTTCAGATAACCTTACCTCACATTTTGGCAATACCAGCTATGATGGCTGCTACAGACATG
ATCGTGACCGTTGCCACCCGGATTGCAAACCGATTTGCTGTAGATTATCACCTGCAAACATTTCCACCCCCAATCACACT
GGACGGTTTTGATATAGCAATGGCATGGCCACACCGCATGGATAATGACACAGCAATTCGATGGTTACGTAATGAACTTG
TTGCAATCGGAGTAGGGCTATAG

Upstream 100 bases:

>100_bases
GCAAGCTCCCACACTTGAGTGACTAGCTCATTTTGACTACAGCTTAACGAGAGTCAGTATATAATTCAAATCAATATTAT
AGATATAGTCTATTCATGAA

Downstream 100 bases:

>100_bases
CCAGGACAATATCTTCCCAAACTGCACGAGCTGCCCTGAGGGTTGGTTGATGTGGAGGTGTGAAAGCAATAGGTCGACGA
TTGCCAGCGCTGCCTTATCT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MDLRGFDLNLLVVLHILLKERSVSKTAERLQLSQPAVSAALNRLRTALKDPILVRDGLQMVPTPRAEQLVEPVQAIVSAI
EQTLADPQPFDYSSISRTFRIATNDYGAFVLVPFLMNRMQKIAPHLTFEIWDIALDVETALREGEIDLVIADAWTLRNCK
CRKTLFSETFTCLVRQNHPRVDTQLTMDDYLQEKHALVSARGRVTGNVDIALSQQNKQRQVQITLPHILAIPAMMAATDM
IVTVATRIANRFAVDYHLQTFPPPITLDGFDIAMAWPHRMDNDTAIRWLRNELVAIGVGL

Sequences:

>Translated_300_residues
MDLRGFDLNLLVVLHILLKERSVSKTAERLQLSQPAVSAALNRLRTALKDPILVRDGLQMVPTPRAEQLVEPVQAIVSAI
EQTLADPQPFDYSSISRTFRIATNDYGAFVLVPFLMNRMQKIAPHLTFEIWDIALDVETALREGEIDLVIADAWTLRNCK
CRKTLFSETFTCLVRQNHPRVDTQLTMDDYLQEKHALVSARGRVTGNVDIALSQQNKQRQVQITLPHILAIPAMMAATDM
IVTVATRIANRFAVDYHLQTFPPPITLDGFDIAMAWPHRMDNDTAIRWLRNELVAIGVGL
>Mature_300_residues
MDLRGFDLNLLVVLHILLKERSVSKTAERLQLSQPAVSAALNRLRTALKDPILVRDGLQMVPTPRAEQLVEPVQAIVSAI
EQTLADPQPFDYSSISRTFRIATNDYGAFVLVPFLMNRMQKIAPHLTFEIWDIALDVETALREGEIDLVIADAWTLRNCK
CRKTLFSETFTCLVRQNHPRVDTQLTMDDYLQEKHALVSARGRVTGNVDIALSQQNKQRQVQITLPHILAIPAMMAATDM
IVTVATRIANRFAVDYHLQTFPPPITLDGFDIAMAWPHRMDNDTAIRWLRNELVAIGVGL

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=296, Percent_Identity=26.6891891891892, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI87081766, Length=284, Percent_Identity=26.056338028169, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1786820, Length=257, Percent_Identity=24.5136186770428, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790147, Length=304, Percent_Identity=21.7105263157895, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33845; Mature: 33845

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLRGFDLNLLVVLHILLKERSVSKTAERLQLSQPAVSAALNRLRTALKDPILVRDGLQM
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEECCCCC
VPTPRAEQLVEPVQAIVSAIEQTLADPQPFDYSSISRTFRIATNDYGAFVLVPFLMNRMQ
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCEEEEEECCCCHHHHHHHHHHHHH
KIAPHLTFEIWDIALDVETALREGEIDLVIADAWTLRNCKCRKTLFSETFTCLVRQNHPR
HHCCCCEEEEEHEEEEHHHHHCCCCEEEEEECCEECCCCHHHHHHHHHHHHHHHCCCCCC
VDTQLTMDDYLQEKHALVSARGRVTGNVDIALSQQNKQRQVQITLPHILAIPAMMAATDM
CCCEECHHHHHHHHHHHHHHCCCEECCEEEEECCCCCCEEEEEECHHHHHHHHHHHHHHH
IVTVATRIANRFAVDYHLQTFPPPITLDGFDIAMAWPHRMDNDTAIRWLRNELVAIGVGL
HHHHHHHHHHHHEEEEEEECCCCCEEECCCEEEEECCCCCCCHHHHHHHHHHHHEEECCC
>Mature Secondary Structure
MDLRGFDLNLLVVLHILLKERSVSKTAERLQLSQPAVSAALNRLRTALKDPILVRDGLQM
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEECCCCC
VPTPRAEQLVEPVQAIVSAIEQTLADPQPFDYSSISRTFRIATNDYGAFVLVPFLMNRMQ
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCEEEEEECCCCHHHHHHHHHHHHH
KIAPHLTFEIWDIALDVETALREGEIDLVIADAWTLRNCKCRKTLFSETFTCLVRQNHPR
HHCCCCEEEEEHEEEEHHHHHCCCCEEEEEECCEECCCCHHHHHHHHHHHHHHHCCCCCC
VDTQLTMDDYLQEKHALVSARGRVTGNVDIALSQQNKQRQVQITLPHILAIPAMMAATDM
CCCEECHHHHHHHHHHHHHHCCCEECCEEEEECCCCCCEEEEEECHHHHHHHHHHHHHHH
IVTVATRIANRFAVDYHLQTFPPPITLDGFDIAMAWPHRMDNDTAIRWLRNELVAIGVGL
HHHHHHHHHHHHEEEEEEECCCCCEEECCCEEEEECCCCCCCHHHHHHHHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]