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The map label for this gene is thrC [H]

Identifier: 158334424

GI number: 158334424

Start: 1230767

End: 1232125

Strand: Direct

Name: thrC [H]

Synonym: AM1_1245

Alternate gene names: 158334424

Gene position: 1230767-1232125 (Clockwise)

Preceding gene: 158334421

Following gene: 158334435

Centisome position: 18.92

GC content: 52.1

Gene sequence:

>1359_bases
ATGTCCCTAGCTCTAGACTCCAAACCCGATACCGATAAACTGACGACTTATTTTCGCTGCATTGCCGGGTGTCCTGGCAA
GCACTCCATCTATGACGTCATATACACCTGTCCCATCTGTGGCAGCTTACTAGAGGTGCATCATGAGCGGGAACCGCTGA
AAAAGCGCAATGCCCTCCAATGGCAGCAATTGCTCAGCTCCCGAGCCAGCACCTCCATCTGGCCCTACGGGAGTGGTGTT
TGGGGCATGCGGGAGTGGGTGGTTCCATCCCTAGCCGATGAAAATGTCGTCAGCATGTTCGAAGGCAATACCAACTTATT
TTGGGCCGAACGCTTAGGCAAACAACTTGGCGTCCCCGACTTATGGATTAAGCTTTGCGGCAATAGCCATACGGGTAGCT
TCAAAGACCTAGGCATGACCGTCTTGGTCAGCGTCGTCAAACAAATGATGGCCCAAGGCAGTTCCGTCAAAGCCGTGGCC
TGCGCCAGTACAGGAGACACCAGCGCCGCCCTCGCCGCCTATGCCGCCTATGCGGGCATACCGGCCATTATTTTCTTGCC
TGCCGGTAAAGTCAGTACGGCTCAGCTTATTCAGCCCGTCTGCAACGGTGCCCATGTCTTAGCCCTCGACACTGACTTCG
ATGGCTGTATGAATATTGTCAAAGAGGTCACGCAAGACAATTCAATTTACCTCGCTAACTCGATGAACAGTCTGCGCATC
GAAGGACAAAAAACCGTCGGCATCGAAATTATTCGGCAGTTTAATTGGCAAGTCCCCGACTGGATCATCATTCCTGTGGG
CAATTTGGGCAATATCAGCGCCCTCTATAAAGGCTTCAAGTTAATGATGGATCTGGGGTTGATCACTCGGATGCCCAGAC
TCGTCGCCGCCCAAACGCAGAAAGCCAATCCTTTTTACGAGTCCTTTAAAAACGGATTCAAAGAAAAAATTAGCGTAACA
GCCCAAGACACCCTAGCCAACGCCATCCGAATTGGTGACCCGGTCAGTTATGACAAAGCCGTCACTGCGATCACCGAAAC
AAACGGTATTGTCGAACAGGCCAGCGAAGACGAATTAGCTGCCGCAGCTGCCAAAGCTGATTTAACTGGGATGTTTACCT
GTCCCCATACAGGCGTTGCCTTAGCCGTTCTCACCAAGCTGATCGAACGGGGTGAAATCAAATCCAGCGATAAAACCGTG
GTGATTAGCACCGCCCACGGTTTGAAGTTCACCGACTTCAAAGTGGGCTACCACGAATCGACCCTGGCTGATGTCAACAG
CCAGCATGCGAACCCTGCTGTTCACCTGCCCGCCAATGCGGATGCCGTCAAAGCTGAAATCGAAAAACGACTGGGCTAA

Upstream 100 bases:

>100_bases
TAGGGTGATTGAATTGAACCCGCGAAGAAACAGCAGTCCATAGCCTTCCAATACAGCTATAAAATAATCTCAAGTGATGA
ATCCATCTCCAGGAACCCCC

Downstream 100 bases:

>100_bases
AAAAGCGCCAACCCTGCCCAGTTAGGGCAGGGTTAATGCTCTCAAGATTAATTGTCTCGTTAGCGAATCACCTTTACAGG
CGTCCCCACGGCGACGAGTT

Product: threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MSLALDSKPDTDKLTTYFRCIAGCPGKHSIYDVIYTCPICGSLLEVHHEREPLKKRNALQWQQLLSSRASTSIWPYGSGV
WGMREWVVPSLADENVVSMFEGNTNLFWAERLGKQLGVPDLWIKLCGNSHTGSFKDLGMTVLVSVVKQMMAQGSSVKAVA
CASTGDTSAALAAYAAYAGIPAIIFLPAGKVSTAQLIQPVCNGAHVLALDTDFDGCMNIVKEVTQDNSIYLANSMNSLRI
EGQKTVGIEIIRQFNWQVPDWIIIPVGNLGNISALYKGFKLMMDLGLITRMPRLVAAQTQKANPFYESFKNGFKEKISVT
AQDTLANAIRIGDPVSYDKAVTAITETNGIVEQASEDELAAAAAKADLTGMFTCPHTGVALAVLTKLIERGEIKSSDKTV
VISTAHGLKFTDFKVGYHESTLADVNSQHANPAVHLPANADAVKAEIEKRLG

Sequences:

>Translated_452_residues
MSLALDSKPDTDKLTTYFRCIAGCPGKHSIYDVIYTCPICGSLLEVHHEREPLKKRNALQWQQLLSSRASTSIWPYGSGV
WGMREWVVPSLADENVVSMFEGNTNLFWAERLGKQLGVPDLWIKLCGNSHTGSFKDLGMTVLVSVVKQMMAQGSSVKAVA
CASTGDTSAALAAYAAYAGIPAIIFLPAGKVSTAQLIQPVCNGAHVLALDTDFDGCMNIVKEVTQDNSIYLANSMNSLRI
EGQKTVGIEIIRQFNWQVPDWIIIPVGNLGNISALYKGFKLMMDLGLITRMPRLVAAQTQKANPFYESFKNGFKEKISVT
AQDTLANAIRIGDPVSYDKAVTAITETNGIVEQASEDELAAAAAKADLTGMFTCPHTGVALAVLTKLIERGEIKSSDKTV
VISTAHGLKFTDFKVGYHESTLADVNSQHANPAVHLPANADAVKAEIEKRLG
>Mature_451_residues
SLALDSKPDTDKLTTYFRCIAGCPGKHSIYDVIYTCPICGSLLEVHHEREPLKKRNALQWQQLLSSRASTSIWPYGSGVW
GMREWVVPSLADENVVSMFEGNTNLFWAERLGKQLGVPDLWIKLCGNSHTGSFKDLGMTVLVSVVKQMMAQGSSVKAVAC
ASTGDTSAALAAYAAYAGIPAIIFLPAGKVSTAQLIQPVCNGAHVLALDTDFDGCMNIVKEVTQDNSIYLANSMNSLRIE
GQKTVGIEIIRQFNWQVPDWIIIPVGNLGNISALYKGFKLMMDLGLITRMPRLVAAQTQKANPFYESFKNGFKEKISVTA
QDTLANAIRIGDPVSYDKAVTAITETNGIVEQASEDELAAAAAKADLTGMFTCPHTGVALAVLTKLIERGEIKSSDKTVV
ISTAHGLKFTDFKVGYHESTLADVNSQHANPAVHLPANADAVKAEIEKRLG

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786185, Length=298, Percent_Identity=25.503355704698, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 48899; Mature: 48767

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLALDSKPDTDKLTTYFRCIAGCPGKHSIYDVIYTCPICGSLLEVHHEREPLKKRNALQ
CCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
WQQLLSSRASTSIWPYGSGVWGMREWVVPSLADENVVSMFEGNTNLFWAERLGKQLGVPD
HHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCCCCHHHHCCCCCCEEHHHHHHHHCCCCH
LWIKLCGNSHTGSFKDLGMTVLVSVVKQMMAQGSSVKAVACASTGDTSAALAAYAAYAGI
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHCC
PAIIFLPAGKVSTAQLIQPVCNGAHVLALDTDFDGCMNIVKEVTQDNSIYLANSMNSLRI
CEEEEECCCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCEEE
EGQKTVGIEIIRQFNWQVPDWIIIPVGNLGNISALYKGFKLMMDLGLITRMPRLVAAQTQ
CCCCHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHCC
KANPFYESFKNGFKEKISVTAQDTLANAIRIGDPVSYDKAVTAITETNGIVEQASEDELA
CCCHHHHHHHHCHHHHEEEEHHHHHHHHHHCCCCCCCCHHHEEEECCCCHHHCCCCHHHH
AAAAKADLTGMFTCPHTGVALAVLTKLIERGEIKSSDKTVVISTAHGLKFTDFKVGYHES
HHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEECCCCCH
TLADVNSQHANPAVHLPANADAVKAEIEKRLG
HHHHCCCCCCCCEEECCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SLALDSKPDTDKLTTYFRCIAGCPGKHSIYDVIYTCPICGSLLEVHHEREPLKKRNALQ
CCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
WQQLLSSRASTSIWPYGSGVWGMREWVVPSLADENVVSMFEGNTNLFWAERLGKQLGVPD
HHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCCCCHHHHCCCCCCEEHHHHHHHHCCCCH
LWIKLCGNSHTGSFKDLGMTVLVSVVKQMMAQGSSVKAVACASTGDTSAALAAYAAYAGI
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHCC
PAIIFLPAGKVSTAQLIQPVCNGAHVLALDTDFDGCMNIVKEVTQDNSIYLANSMNSLRI
CEEEEECCCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCEEE
EGQKTVGIEIIRQFNWQVPDWIIIPVGNLGNISALYKGFKLMMDLGLITRMPRLVAAQTQ
CCCCHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHCC
KANPFYESFKNGFKEKISVTAQDTLANAIRIGDPVSYDKAVTAITETNGIVEQASEDELA
CCCHHHHHHHHCHHHHEEEEHHHHHHHHHHCCCCCCCCHHHEEEECCCCHHHCCCCHHHH
AAAAKADLTGMFTCPHTGVALAVLTKLIERGEIKSSDKTVVISTAHGLKFTDFKVGYHES
HHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEECCCCCH
TLADVNSQHANPAVHLPANADAVKAEIEKRLG
HHHHCCCCCCCCEEECCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]