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The map label for this gene is aroC

Identifier: 158334320

GI number: 158334320

Start: 1109770

End: 1110864

Strand: Reverse

Name: aroC

Synonym: AM1_1139

Alternate gene names: 158334320

Gene position: 1110864-1109770 (Counterclockwise)

Preceding gene: 158334321

Following gene: 158334319

Centisome position: 17.08

GC content: 49.86

Gene sequence:

>1095_bases
ATGGGAAATACCTTTGGACATTTATTTCGGATTACAACCTTTGGTGAATCTCATGGTGGTGGTGTTGGGGTTGTTATTGA
TGGCTGCCCACCTCAAATTGAAATTGCGGCAGAAGACATTCAGTTTGAGTTAGATCGTCGACGACCGGGGCAAAGTCGAA
TTACCACGCCCCGTAAAGAAACAGATACCTGCGAAATCGTTTCGGGCATGTTTCAGGGAAAAACATTAGGGACACCGATC
ACCATTTTGGTGCGGAATAAAGATACTCGCCCCCAAGACTACAGTGAGATGGCCCAGGTCTATCGTCCGTCCCATGCGGA
TGCCACCTATGACGCGAAATATGGCATTCGGAATTGGCAAGGAGGTGGCCGCTCATCTGCTCGGGAAACCATTGGTCGAG
TCGCGGCAGGGGCGATTGCGAAAAAGATTCTTCAGCAAGCGGCTGGGGTGGAGGTGATCGGCTATGTCAAACGGATTAAA
ACCGTGGAAGCGGATATTGATCCAGATCAAGTGACCTTAGCTCAGGTAGAAGCCAATATGGTGCGCTGTCCCAATCCTGA
AACTGCAGAGGAAATGATTGATTTGATCGATCAAACCCGACGAGATGCTAATTCGATCGGAGGAGTGGTGGAATGTGTGG
CTCGTCAGGTGCCGAAAGGATTAGGCGCTCCTGTCTTTGACAAGCTGGAGGCCGAACTAGCCAAAGCAGTGATGTCTTTG
CCTGCCTGTAAAGGGTTTGAGATTGGCTCTGGGTTTGCGGGTACTCAGCTGACGGGGCTAGAACATAATGATGAGTTTTA
TACCGATGAGACAGGTCGTATTCGAACTGTAACCAATCGGTCTGGTGGGATCCAAGGTGGCATTTCTAATGGCGAAAATA
TTGTGCTGCGGGCGGCATTTAAACCAACCGCAACCATTGGCAAACCCCAAAAAACGGTCAATCAGGCTGGTGAAGCCACA
ACATTAGCAGCGAAAGGCCGCCATGATCCTTGCGTATTGCCGAGGGCCGTACCTATGGTAGAAGCGATGGTTGCTTTAGT
GTTGTGCGATCATCTACTCCGCCATCATGCCCAGTGTGAATTGTTGACAGAGTAA

Upstream 100 bases:

>100_bases
AATATTTCCCTCTCTTTTTTTGGCTATTTAACAAGGTCGAATGAGATAGTGAAGACAGGCAGCTTGCCCGGTATATGTTT
AGCACGGTCAGATCAAGAGC

Downstream 100 bases:

>100_bases
TTTTGTTGGAATTACATCGCCCATGCGATTGCTGTTGATTCGCCATGCCGAGGCCCAGGGAAATGCCCAACATAGGATGT
TAGGGCAGTTAGATGAGCTA

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MGNTFGHLFRITTFGESHGGGVGVVIDGCPPQIEIAAEDIQFELDRRRPGQSRITTPRKETDTCEIVSGMFQGKTLGTPI
TILVRNKDTRPQDYSEMAQVYRPSHADATYDAKYGIRNWQGGGRSSARETIGRVAAGAIAKKILQQAAGVEVIGYVKRIK
TVEADIDPDQVTLAQVEANMVRCPNPETAEEMIDLIDQTRRDANSIGGVVECVARQVPKGLGAPVFDKLEAELAKAVMSL
PACKGFEIGSGFAGTQLTGLEHNDEFYTDETGRIRTVTNRSGGIQGGISNGENIVLRAAFKPTATIGKPQKTVNQAGEAT
TLAAKGRHDPCVLPRAVPMVEAMVALVLCDHLLRHHAQCELLTE

Sequences:

>Translated_364_residues
MGNTFGHLFRITTFGESHGGGVGVVIDGCPPQIEIAAEDIQFELDRRRPGQSRITTPRKETDTCEIVSGMFQGKTLGTPI
TILVRNKDTRPQDYSEMAQVYRPSHADATYDAKYGIRNWQGGGRSSARETIGRVAAGAIAKKILQQAAGVEVIGYVKRIK
TVEADIDPDQVTLAQVEANMVRCPNPETAEEMIDLIDQTRRDANSIGGVVECVARQVPKGLGAPVFDKLEAELAKAVMSL
PACKGFEIGSGFAGTQLTGLEHNDEFYTDETGRIRTVTNRSGGIQGGISNGENIVLRAAFKPTATIGKPQKTVNQAGEAT
TLAAKGRHDPCVLPRAVPMVEAMVALVLCDHLLRHHAQCELLTE
>Mature_363_residues
GNTFGHLFRITTFGESHGGGVGVVIDGCPPQIEIAAEDIQFELDRRRPGQSRITTPRKETDTCEIVSGMFQGKTLGTPIT
ILVRNKDTRPQDYSEMAQVYRPSHADATYDAKYGIRNWQGGGRSSARETIGRVAAGAIAKKILQQAAGVEVIGYVKRIKT
VEADIDPDQVTLAQVEANMVRCPNPETAEEMIDLIDQTRRDANSIGGVVECVARQVPKGLGAPVFDKLEAELAKAVMSLP
ACKGFEIGSGFAGTQLTGLEHNDEFYTDETGRIRTVTNRSGGIQGGISNGENIVLRAAFKPTATIGKPQKTVNQAGEATT
LAAKGRHDPCVLPRAVPMVEAMVALVLCDHLLRHHAQCELLTE

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:
GO:0004107: Chorismate synthase
GO:0008652: Chorismate synthase
GO:0009073: Chorismate synthase
GO:0016829: Chorismate synthase

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=357, Percent_Identity=50.140056022409, Blast_Score=333, Evalue=7e-93,
Organism=Saccharomyces cerevisiae, GI6321290, Length=367, Percent_Identity=54.4959128065395, Blast_Score=394, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_ACAM1 (B0C2W2)

Other databases:

- EMBL:   CP000828
- RefSeq:   YP_001515492.1
- ProteinModelPortal:   B0C2W2
- SMR:   B0C2W2
- GeneID:   5679964
- GenomeReviews:   CP000828_GR
- KEGG:   amr:AM1_1139
- HOGENOM:   HBG292336
- OMA:   TATIGKE
- ProtClustDB:   PRK05382
- BioCyc:   AMAR329726:AM1_1139-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 39234; Mature: 39103

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNTFGHLFRITTFGESHGGGVGVVIDGCPPQIEIAAEDIQFELDRRRPGQSRITTPRKE
CCCCCEEEEEEEECCCCCCCEEEEEECCCCCCEEEECCCCEEEHHCCCCCCCCCCCCCCC
TDTCEIVSGMFQGKTLGTPITILVRNKDTRPQDYSEMAQVYRPSHADATYDAKYGIRNWQ
CCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCC
GGGRSSARETIGRVAAGAIAKKILQQAAGVEVIGYVKRIKTVEADIDPDQVTLAQVEANM
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEHEEHHCCC
VRCPNPETAEEMIDLIDQTRRDANSIGGVVECVARQVPKGLGAPVFDKLEAELAKAVMSL
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHC
PACKGFEIGSGFAGTQLTGLEHNDEFYTDETGRIRTVTNRSGGIQGGISNGENIVLRAAF
CCCCCCCCCCCCCCCEEECCCCCCCEEECCCCCEEEEECCCCCCCCCCCCCCEEEEEEEC
KPTATIGKPQKTVNQAGEATTLAAKGRHDPCVLPRAVPMVEAMVALVLCDHLLRHHAQCE
CCCCCCCCCHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCE
LLTE
ECCC
>Mature Secondary Structure 
GNTFGHLFRITTFGESHGGGVGVVIDGCPPQIEIAAEDIQFELDRRRPGQSRITTPRKE
CCCCEEEEEEEECCCCCCCEEEEEECCCCCCEEEECCCCEEEHHCCCCCCCCCCCCCCC
TDTCEIVSGMFQGKTLGTPITILVRNKDTRPQDYSEMAQVYRPSHADATYDAKYGIRNWQ
CCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCC
GGGRSSARETIGRVAAGAIAKKILQQAAGVEVIGYVKRIKTVEADIDPDQVTLAQVEANM
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEHEEHHCCC
VRCPNPETAEEMIDLIDQTRRDANSIGGVVECVARQVPKGLGAPVFDKLEAELAKAVMSL
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHC
PACKGFEIGSGFAGTQLTGLEHNDEFYTDETGRIRTVTNRSGGIQGGISNGENIVLRAAF
CCCCCCCCCCCCCCCEEECCCCCCCEEECCCCCEEEEECCCCCCCCCCCCCCEEEEEEEC
KPTATIGKPQKTVNQAGEATTLAAKGRHDPCVLPRAVPMVEAMVALVLCDHLLRHHAQCE
CCCCCCCCCHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCE
LLTE
ECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA