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The map label for this gene is fur [H]

Identifier: 158334312

GI number: 158334312

Start: 1104493

End: 1104936

Strand: Direct

Name: fur [H]

Synonym: AM1_1131

Alternate gene names: 158334312

Gene position: 1104493-1104936 (Clockwise)

Preceding gene: 158334308

Following gene: 158334315

Centisome position: 16.98

GC content: 43.24

Gene sequence:

>444_bases
ATGTATACTTCTAGCTCACTCAAAGCCGAATTAAATGAGAAAGGTTGGCGACTGACTCCTCAGCGGGAAATAATATTGAC
GGCCTTCCAAGAATTGGAGAAAGGGCAACATCTCAGCGCTGAAGATCTCTACGAGCTGTTAATGCAACAAGGTAATCCCA
TCAGCCTTTCCACCATTTATAGAAACACTAAGCTTATGTCCCATATGGGAATACTCCGAGAGCTGGAATTCGCTGAAGGG
CATAAGCACTATGAGCTAAATCAACCCTACCCGAATCATCACCATCACCTGATATGCGTCAAATGTAATCAGACGATTGA
GTTTAAAAGCGATTCCATCCTCAAAGTGGGGAAAAGTAAAGCGAAGCAATCTGGATTTCATCTCTTAGACTGTCAATTGA
CGATCCATGCCATTTGCCCAACTTGCAAAATTGCAAAGGGGTAG

Upstream 100 bases:

>100_bases
TGGAAACAATATCACAACCTCAGCTATAACTATCCGCTGCCCTTATATACAGGAATCTATCCCCTCAGGCCCATAGGAAA
ATATCTTGTCAGGACGGTAC

Downstream 100 bases:

>100_bases
CGATCCGCCCCTCTTGCCTGAACCCAATTATTTAATTTCTAAGGCTTCTGAACCGCCTTCCTCTAAAGTTCTTAGAAGTA
TTCCCAGCTGATACCACACC

Product: ferric uptake regulation protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MYTSSSLKAELNEKGWRLTPQREIILTAFQELEKGQHLSAEDLYELLMQQGNPISLSTIYRNTKLMSHMGILRELEFAEG
HKHYELNQPYPNHHHHLICVKCNQTIEFKSDSILKVGKSKAKQSGFHLLDCQLTIHAICPTCKIAKG

Sequences:

>Translated_147_residues
MYTSSSLKAELNEKGWRLTPQREIILTAFQELEKGQHLSAEDLYELLMQQGNPISLSTIYRNTKLMSHMGILRELEFAEG
HKHYELNQPYPNHHHHLICVKCNQTIEFKSDSILKVGKSKAKQSGFHLLDCQLTIHAICPTCKIAKG
>Mature_147_residues
MYTSSSLKAELNEKGWRLTPQREIILTAFQELEKGQHLSAEDLYELLMQQGNPISLSTIYRNTKLMSHMGILRELEFAEG
HKHYELNQPYPNHHHHLICVKCNQTIEFKSDSILKVGKSKAKQSGFHLLDCQLTIHAICPTCKIAKG

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulates genes involved in iron scavenging or photosynthetic electron transport [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=130, Percent_Identity=36.1538461538462, Blast_Score=77, Evalue=3e-16,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16844; Mature: 16844

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTSSSLKAELNEKGWRLTPQREIILTAFQELEKGQHLSAEDLYELLMQQGNPISLSTIY
CCCCCCHHHHHCCCCCEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEHHHH
RNTKLMSHMGILRELEFAEGHKHYELNQPYPNHHHHLICVKCNQTIEFKSDSILKVGKSK
HHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCEEEEEEECCEEEECCCCHHHHHHHH
AKQSGFHLLDCQLTIHAICPTCKIAKG
HHHCCCEEEEEEEEEEECCCCEEECCC
>Mature Secondary Structure
MYTSSSLKAELNEKGWRLTPQREIILTAFQELEKGQHLSAEDLYELLMQQGNPISLSTIY
CCCCCCHHHHHCCCCCEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEHHHH
RNTKLMSHMGILRELEFAEGHKHYELNQPYPNHHHHLICVKCNQTIEFKSDSILKVGKSK
HHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCEEEEEEECCEEEECCCCHHHHHHHH
AKQSGFHLLDCQLTIHAICPTCKIAKG
HHHCCCEEEEEEEEEEECCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8704986 [H]