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The map label for this gene is uppP

Identifier: 158334246

GI number: 158334246

Start: 1032608

End: 1033408

Strand: Direct

Name: uppP

Synonym: AM1_1064

Alternate gene names: 158334246

Gene position: 1032608-1033408 (Clockwise)

Preceding gene: 158334242

Following gene: 158334250

Centisome position: 15.88

GC content: 50.19

Gene sequence:

>801_bases
ATGACCTTACTGCAAGCAATTATTTTGGGGATTGTGCAGGGGCTCACAGAGTTTCTGCCCGTCTCCAGCTCTGGGCATTT
AGTGCTCGCCAGCTATTACTTAGGTTGGTGGGAAAAGCTACCCCTTTATGTAGATATCGCCACCAATACAGGCACATTCT
TCGCCGTTCTAGTTGTCCTCCGTAAAGATGTCTGGCAAGCTTTATCTGGCTTTTTTGCGGGCCTGACTTCGTCTACGGCT
CGGCAACAAGAGGGATGGCGAATGGCGTTACTGGTGGTTTTAGGATCCATCCCCACAGCCATGATTGGGTTGGGCTTGAA
ACCCATTTTTGAGGAACTCAATCAGCCTCTCTATGTGTCCTTTGCCTTGATCGTGACTGGGCTGGTGTTATGGTTCACCC
CCAAGTCCGGTCTCAAGCGCAATGCCATGTCCCTTAGCTGGCTGGATGCCACCATTGGCGGCATTGCTCAAGGATGTGCT
GTTATTCCAGGCATCTCCCGGTCTGGCAGCACCATTTCCACTATGTTGTGGCGCGGTGCGACCTCCGATTTAGCCCCCCG
ATTTTCTTTTCTCATGTATTTGGTGGTGTCCTTTGGTGTAGCTATTTTGGGCATTGATGAAGTGCGAGAAGAAGGACTAC
AACTCGCTCCCCTTCTAGGCATGATTATTGCCTCTTTTGTTACGGGCTACATCGCGTTGCTTTGGCTGTTTTCCGTTTTA
AAAAAGGGACAGTTCAAATGGTTTGCCCCCTACCTCTGGGTCGTTGCGGCGATCACATTAATTAAAGTTGCCATGGGCTA
G

Upstream 100 bases:

>100_bases
TCGTCCTTAACCATCCTTGGTTACTCCATACCTCGGTTATTAATGGTAAATTCGCCAAGGATATTAAAACAACGCGATTT
CTCTTCTCCTCTAAACGCCT

Downstream 100 bases:

>100_bases
CCCGCCTCTAAAAATGATCGCTCAGCCATGGTTGAGGGCCACTAAAGAGCGTGGTTGCCAAAGCTAGCACCTCCCTCGAT
CCATCTACAGCCCCCAGCAG

Product: undecaprenyl-diphosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MTLLQAIILGIVQGLTEFLPVSSSGHLVLASYYLGWWEKLPLYVDIATNTGTFFAVLVVLRKDVWQALSGFFAGLTSSTA
RQQEGWRMALLVVLGSIPTAMIGLGLKPIFEELNQPLYVSFALIVTGLVLWFTPKSGLKRNAMSLSWLDATIGGIAQGCA
VIPGISRSGSTISTMLWRGATSDLAPRFSFLMYLVVSFGVAILGIDEVREEGLQLAPLLGMIIASFVTGYIALLWLFSVL
KKGQFKWFAPYLWVVAAITLIKVAMG

Sequences:

>Translated_266_residues
MTLLQAIILGIVQGLTEFLPVSSSGHLVLASYYLGWWEKLPLYVDIATNTGTFFAVLVVLRKDVWQALSGFFAGLTSSTA
RQQEGWRMALLVVLGSIPTAMIGLGLKPIFEELNQPLYVSFALIVTGLVLWFTPKSGLKRNAMSLSWLDATIGGIAQGCA
VIPGISRSGSTISTMLWRGATSDLAPRFSFLMYLVVSFGVAILGIDEVREEGLQLAPLLGMIIASFVTGYIALLWLFSVL
KKGQFKWFAPYLWVVAAITLIKVAMG
>Mature_265_residues
TLLQAIILGIVQGLTEFLPVSSSGHLVLASYYLGWWEKLPLYVDIATNTGTFFAVLVVLRKDVWQALSGFFAGLTSSTAR
QQEGWRMALLVVLGSIPTAMIGLGLKPIFEELNQPLYVSFALIVTGLVLWFTPKSGLKRNAMSLSWLDATIGGIAQGCAV
IPGISRSGSTISTMLWRGATSDLAPRFSFLMYLVVSFGVAILGIDEVREEGLQLAPLLGMIIASFVTGYIALLWLFSVLK
KGQFKWFAPYLWVVAAITLIKVAMG

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=268, Percent_Identity=32.8358208955224, Blast_Score=106, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_ACAM1 (B0C1T8)

Other databases:

- EMBL:   CP000828
- RefSeq:   YP_001515418.1
- GeneID:   5679889
- GenomeReviews:   CP000828_GR
- KEGG:   amr:AM1_1064
- HOGENOM:   HBG391969
- OMA:   KEIDWIF
- BioCyc:   AMAR329726:AM1_1064-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 28930; Mature: 28799

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x208f1db4)-; HASH(0x23549a6c)-; HASH(0x23122bd8)-; HASH(0x20a0fd2c)-; HASH(0x22cb1b40)-; HASH(0x40be337c)-; HASH(0x23423bac)-; HASH(0x229df12c)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLQAIILGIVQGLTEFLPVSSSGHLVLASYYLGWWEKLPLYVDIATNTGTFFAVLVVL
CHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHH
RKDVWQALSGFFAGLTSSTARQQEGWRMALLVVLGSIPTAMIGLGLKPIFEELNQPLYVS
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHH
FALIVTGLVLWFTPKSGLKRNAMSLSWLDATIGGIAQGCAVIPGISRSGSTISTMLWRGA
HHHHHHHHHHHCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCC
TSDLAPRFSFLMYLVVSFGVAILGIDEVREEGLQLAPLLGMIIASFVTGYIALLWLFSVL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKGQFKWFAPYLWVVAAITLIKVAMG
HCCCCHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure 
TLLQAIILGIVQGLTEFLPVSSSGHLVLASYYLGWWEKLPLYVDIATNTGTFFAVLVVL
HHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHH
RKDVWQALSGFFAGLTSSTARQQEGWRMALLVVLGSIPTAMIGLGLKPIFEELNQPLYVS
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHH
FALIVTGLVLWFTPKSGLKRNAMSLSWLDATIGGIAQGCAVIPGISRSGSTISTMLWRGA
HHHHHHHHHHHCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCC
TSDLAPRFSFLMYLVVSFGVAILGIDEVREEGLQLAPLLGMIIASFVTGYIALLWLFSVL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKGQFKWFAPYLWVVAAITLIKVAMG
HCCCCHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA