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The map label for this gene is ribH [H]

Identifier: 158334192

GI number: 158334192

Start: 978272

End: 978865

Strand: Reverse

Name: ribH [H]

Synonym: AM1_1010

Alternate gene names: 158334192

Gene position: 978865-978272 (Counterclockwise)

Preceding gene: 158334193

Following gene: 158334191

Centisome position: 15.05

GC content: 47.98

Gene sequence:

>594_bases
ATGGCTGTCTTTGAAGGCAAATTTACGCATTCGGCATCCTTCCGGTTTGCTATTGTTATTGGGCGTTTCAATGATCTAGT
GACCAGCAAGCTGCTAGCAGGTTGCCAAGACTGTCTACAGCGTCATGGCGTTGATACCCATGAGACCGGAAGTCAGGTTG
ACTATATCTGGGTACCAGGAGGTTTTGAGATCCCCCTAGTGGCTCGACAGCTAGCTTTATCTCATGGTTACGATGCCATC
ATTTGCCTGGGTGCAGTTATCCGCGGTCAAACCCCTCATTTTGACTATGTTGCCGGTGAAGTTTCGAAAGGAATAGCGGC
TACTAGTTTGCAAACGGGTGTTCCACTTATCTTTGGCATTTTGACTGTTGATAGTATGCAACAAGCCCTGGAGCGGGCAG
GCATAAAAAGCAACAAAGGCTGGGACTTTGCCATGAATGCCTTGGAAATGGCTAGCCTAATGCACCAGCTCCGTCCACAG
CTTGCTGTAGCGGATGCGAGCAATCAAAATCTAGGTGAAGCTGCCGTATTGCCTCCAAGTGTAAGTAGCGCCCAAATTCC
TAACGCTTTAAAGTCGGAATCCAATAATTCCTAA

Upstream 100 bases:

>100_bases
TGAGTATTCTATGTTTCGTGCATCAAGCTCAAGTGTTTTAGGAATCGCTCGTATATTCTTATCTGTGTCTCTAAATTGAT
AAAGGTAAAGGCAAACTGGA

Downstream 100 bases:

>100_bases
TTTATTGACAGACTCGGCTACATTTGAGAAGCTAGATAGGCAGAAGATTTATTTGCGGGTATAGCTCAGTGGTAGAGCGT
CACCTTGCCAAGGTGAATGT

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MAVFEGKFTHSASFRFAIVIGRFNDLVTSKLLAGCQDCLQRHGVDTHETGSQVDYIWVPGGFEIPLVARQLALSHGYDAI
ICLGAVIRGQTPHFDYVAGEVSKGIAATSLQTGVPLIFGILTVDSMQQALERAGIKSNKGWDFAMNALEMASLMHQLRPQ
LAVADASNQNLGEAAVLPPSVSSAQIPNALKSESNNS

Sequences:

>Translated_197_residues
MAVFEGKFTHSASFRFAIVIGRFNDLVTSKLLAGCQDCLQRHGVDTHETGSQVDYIWVPGGFEIPLVARQLALSHGYDAI
ICLGAVIRGQTPHFDYVAGEVSKGIAATSLQTGVPLIFGILTVDSMQQALERAGIKSNKGWDFAMNALEMASLMHQLRPQ
LAVADASNQNLGEAAVLPPSVSSAQIPNALKSESNNS
>Mature_196_residues
AVFEGKFTHSASFRFAIVIGRFNDLVTSKLLAGCQDCLQRHGVDTHETGSQVDYIWVPGGFEIPLVARQLALSHGYDAII
CLGAVIRGQTPHFDYVAGEVSKGIAATSLQTGVPLIFGILTVDSMQQALERAGIKSNKGWDFAMNALEMASLMHQLRPQL
AVADASNQNLGEAAVLPPSVSSAQIPNALKSESNNS

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=145, Percent_Identity=45.5172413793103, Blast_Score=134, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6324429, Length=150, Percent_Identity=30.6666666666667, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 21040; Mature: 20909

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVFEGKFTHSASFRFAIVIGRFNDLVTSKLLAGCQDCLQRHGVDTHETGSQVDYIWVPG
CCEECCCCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECC
GFEIPLVARQLALSHGYDAIICLGAVIRGQTPHFDYVAGEVSKGIAATSLQTGVPLIFGI
CCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHCCHHHHHHH
LTVDSMQQALERAGIKSNKGWDFAMNALEMASLMHQLRPQLAVADASNQNLGEAAVLPPS
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEECCCC
VSSAQIPNALKSESNNS
CCCHHCCHHHHCCCCCC
>Mature Secondary Structure 
AVFEGKFTHSASFRFAIVIGRFNDLVTSKLLAGCQDCLQRHGVDTHETGSQVDYIWVPG
CEECCCCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECC
GFEIPLVARQLALSHGYDAIICLGAVIRGQTPHFDYVAGEVSKGIAATSLQTGVPLIFGI
CCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHCCHHHHHHH
LTVDSMQQALERAGIKSNKGWDFAMNALEMASLMHQLRPQLAVADASNQNLGEAAVLPPS
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEECCCC
VSSAQIPNALKSESNNS
CCCHHCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA