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The map label for this gene is 158334155

Identifier: 158334155

GI number: 158334155

Start: 944849

End: 946549

Strand: Direct

Name: 158334155

Synonym: AM1_0971

Alternate gene names: NA

Gene position: 944849-946549 (Clockwise)

Preceding gene: 158334154

Following gene: 158334156

Centisome position: 14.53

GC content: 49.38

Gene sequence:

>1701_bases
ATGAAATTTGCTGCTAGTCTTCCGGTTGTTTTGGTTGGGGCTGCTGCCGTGGTGGTGCAACCCCAGATTAGTCACGCTTT
AAATGCGGCTGAAGTTGCCAAAATTGCCCGCAATGTCACGGTCCGAGTCGATAGTCAAGCACCCGGTTCCGGGGTGATTA
TTAAGCAGGATGGAGACACCTATACGGTGTTAACGGCAGCCCATGTGGTGGGCAGCGAAGATACTTATGAAGTGATCACG
CCGGATCGGGCTCGACATTCGGTGGCCAATACAACTATCCAGCGGTTACCCAATGTCGATCTGGCGTTGATTCAGTTTTC
TAGTAGCCAGGCTTATAAGGTGGCAGAAGTGGGCAATGCCCAGCAAATTTCTGCGGGAATGCCCTGCTATGTTGCAGGAT
TCCCAGGGAAAACGGCGGCCATCAATGAGGTGGTTTACAACTTTACAGCCGGACAAATTACGGCGAATGCTGTGCAACCT
TTACGAGATGGGTATGGACTGGTCTATTCCAATGCCACGTTGCCAGGGATGAGTGGTGGCGCGGTTCTAGATAGCCAAGG
TCAACTGATTGGGATTCATGGTCGAGCAGATACGACGCCTCAAGCCCAAAATCCTAATCTGAATCCCGATATTTACGTCA
AAACCGGATTTAACTTAGGCATTCCTATCAATACATTTTTGCAAAAAGCCGACGATGCCAACCTGGATTTGGGCTTTACG
ACGCCACCACCCAAACCCGCTGCTCCTGCATCGGTTGATCAAGCGCTGGCTGAGGCAGGACAGGCTTTAGGCCGGGGAGA
GAGTAGCAAAGCGGTCTCTAAGTTTAATCAGGTATTGGGGAGCGATCGCAAAGCCGTAGCGCTACATGGCCGAGGATTAG
CCCATTACCAACGAGGTAATTACAAGGAAGCTTTAGCAGACTTGAACCATGCGATCGCCATCGATCCTTATAACGCTTTG
TTCTTCAACAGTCGAGGGTCAGTCCATTTAGCCCAGGCGCTCCAGCCTAATCGAAATCTACAGTCTGGGGCCTCACGGGC
CGAGAGAGATTTTAGTGAAGCCCTTAAGCTCAATCCCGACGATAGCAATGCTTACAATAATCGCGGATTAGCCAACTTCT
ATATGGGTGCCAGAACCCAAGCAATTGACGATTACAATCAGGCTTTGCGTCTAGATCCGGGATTGGCCAAAGCCTATAAA
AATCGAGGGTTCACTCGCTGGCTAGAGCAAGATATTCGCGGCGCTTTGTTGGATCTCAAGCAAGCCCTCACCATCGATCC
AACCTACGCACCAGCCTATCAAACCCGTGGTCGGTTACAGTTTCGACAGGGAGAAGTAGCTAAGGCAATAGCCGATTACG
ATCAGGCTATCCAGTTAAAACCGAAAGCGGGTAAAACCTATATTTATCGAGGAATTGCCCGCTATGAGAACTCCGAAGTT
CCTGGAGCAATCCAAGACTGGCAAGCTGCCATTAAAGCTAGTCCCGAAGAGTCTGCTGGTGCTCATTTGCTGATTGGTGC
GACTTTATTAACTCAAGGTCGAGAAAATGAGGCTTTACAGAAATTGAAAACAGCTAAACAACTTGAACGAACCTGGACCA
ATCAAGGCTTTCTAAGCCAAGTGTTAGGCAAACGGTTACTGAAGGAGGCTACTGCATTACTGGAGCATCCTAAGGCTCAA
GCATTACTTAAATCCCGCTAA

Upstream 100 bases:

>100_bases
TAGAGAAACAACTGTCAATTTATTACGGTCAAAGTTTATGAGGTTATGGGATGGGGCATGCTAGAACGTATCCATTGCGA
CAATTTTAATAAACGAAGTG

Downstream 100 bases:

>100_bases
TAGCGTTTGGTGGGCCTCATGTTGTTCAGAAAAGAGAAGCAGCCTCTTAAGGGCTAAATTTTAGAAATTTCGGAATTATA
CCTGATGTAGCTGGAGCAGT

Product: TPR domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 566; Mature: 566

Protein sequence:

>566_residues
MKFAASLPVVLVGAAAVVVQPQISHALNAAEVAKIARNVTVRVDSQAPGSGVIIKQDGDTYTVLTAAHVVGSEDTYEVIT
PDRARHSVANTTIQRLPNVDLALIQFSSSQAYKVAEVGNAQQISAGMPCYVAGFPGKTAAINEVVYNFTAGQITANAVQP
LRDGYGLVYSNATLPGMSGGAVLDSQGQLIGIHGRADTTPQAQNPNLNPDIYVKTGFNLGIPINTFLQKADDANLDLGFT
TPPPKPAAPASVDQALAEAGQALGRGESSKAVSKFNQVLGSDRKAVALHGRGLAHYQRGNYKEALADLNHAIAIDPYNAL
FFNSRGSVHLAQALQPNRNLQSGASRAERDFSEALKLNPDDSNAYNNRGLANFYMGARTQAIDDYNQALRLDPGLAKAYK
NRGFTRWLEQDIRGALLDLKQALTIDPTYAPAYQTRGRLQFRQGEVAKAIADYDQAIQLKPKAGKTYIYRGIARYENSEV
PGAIQDWQAAIKASPEESAGAHLLIGATLLTQGRENEALQKLKTAKQLERTWTNQGFLSQVLGKRLLKEATALLEHPKAQ
ALLKSR

Sequences:

>Translated_566_residues
MKFAASLPVVLVGAAAVVVQPQISHALNAAEVAKIARNVTVRVDSQAPGSGVIIKQDGDTYTVLTAAHVVGSEDTYEVIT
PDRARHSVANTTIQRLPNVDLALIQFSSSQAYKVAEVGNAQQISAGMPCYVAGFPGKTAAINEVVYNFTAGQITANAVQP
LRDGYGLVYSNATLPGMSGGAVLDSQGQLIGIHGRADTTPQAQNPNLNPDIYVKTGFNLGIPINTFLQKADDANLDLGFT
TPPPKPAAPASVDQALAEAGQALGRGESSKAVSKFNQVLGSDRKAVALHGRGLAHYQRGNYKEALADLNHAIAIDPYNAL
FFNSRGSVHLAQALQPNRNLQSGASRAERDFSEALKLNPDDSNAYNNRGLANFYMGARTQAIDDYNQALRLDPGLAKAYK
NRGFTRWLEQDIRGALLDLKQALTIDPTYAPAYQTRGRLQFRQGEVAKAIADYDQAIQLKPKAGKTYIYRGIARYENSEV
PGAIQDWQAAIKASPEESAGAHLLIGATLLTQGRENEALQKLKTAKQLERTWTNQGFLSQVLGKRLLKEATALLEHPKAQ
ALLKSR
>Mature_566_residues
MKFAASLPVVLVGAAAVVVQPQISHALNAAEVAKIARNVTVRVDSQAPGSGVIIKQDGDTYTVLTAAHVVGSEDTYEVIT
PDRARHSVANTTIQRLPNVDLALIQFSSSQAYKVAEVGNAQQISAGMPCYVAGFPGKTAAINEVVYNFTAGQITANAVQP
LRDGYGLVYSNATLPGMSGGAVLDSQGQLIGIHGRADTTPQAQNPNLNPDIYVKTGFNLGIPINTFLQKADDANLDLGFT
TPPPKPAAPASVDQALAEAGQALGRGESSKAVSKFNQVLGSDRKAVALHGRGLAHYQRGNYKEALADLNHAIAIDPYNAL
FFNSRGSVHLAQALQPNRNLQSGASRAERDFSEALKLNPDDSNAYNNRGLANFYMGARTQAIDDYNQALRLDPGLAKAYK
NRGFTRWLEQDIRGALLDLKQALTIDPTYAPAYQTRGRLQFRQGEVAKAIADYDQAIQLKPKAGKTYIYRGIARYENSEV
PGAIQDWQAAIKASPEESAGAHLLIGATLLTQGRENEALQKLKTAKQLERTWTNQGFLSQVLGKRLLKEATALLEHPKAQ
ALLKSR

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI310131789, Length=244, Percent_Identity=26.6393442622951, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI310110582, Length=244, Percent_Identity=26.6393442622951, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI310123097, Length=244, Percent_Identity=26.6393442622951, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI32307150, Length=172, Percent_Identity=27.906976744186, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI32307148, Length=172, Percent_Identity=27.906976744186, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI170784867, Length=251, Percent_Identity=24.3027888446215, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115532690, Length=228, Percent_Identity=25.8771929824561, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115532692, Length=228, Percent_Identity=25.8771929824561, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 60818; Mature: 60818

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFAASLPVVLVGAAAVVVQPQISHALNAAEVAKIARNVTVRVDSQAPGSGVIIKQDGDT
CCCCCCCCCCEECCCCEEECCHHHHHCCHHHHHHHHCCEEEEECCCCCCCCEEEEECCCE
YTVLTAAHVVGSEDTYEVITPDRARHSVANTTIQRLPNVDLALIQFSSSQAYKVAEVGNA
EEEEEEEHHHCCCCCEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEHHCCCC
QQISAGMPCYVAGFPGKTAAINEVVYNFTAGQITANAVQPLRDGYGLVYSNATLPGMSGG
HHHCCCCCEEEECCCCCHHHHHHHHHCCCCCCEEHHHHHHHHCCCEEEEECCCCCCCCCC
AVLDSQGQLIGIHGRADTTPQAQNPNLNPDIYVKTGFNLGIPINTFLQKADDANLDLGFT
EEEECCCCEEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHCCCCCCCEECCC
TPPPKPAAPASVDQALAEAGQALGRGESSKAVSKFNQVLGSDRKAVALHGRGLAHYQRGN
CCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHCCCC
YKEALADLNHAIAIDPYNALFFNSRGSVHLAQALQPNRNLQSGASRAERDFSEALKLNPD
HHHHHHHCCCEEEECCCCEEEECCCCCEEEHHHCCCCCCHHHHHHHHHHHHHHHHCCCCC
DSNAYNNRGLANFYMGARTQAIDDYNQALRLDPGLAKAYKNRGFTRWLEQDIRGALLDLK
CCCCCCCCCCHHHHHCCCHHHHHHHHHHEECCCHHHHHHHCCCHHHHHHHHHHHHHHHHH
QALTIDPTYAPAYQTRGRLQFRQGEVAKAIADYDQAIQLKPKAGKTYIYRGIARYENSEV
HHHCCCCCCCCCHHCCCCEEECCCHHHHHHHCCCHHEEECCCCCCCHHHHHHHHCCCCCC
PGAIQDWQAAIKASPEESAGAHLLIGATLLTQGRENEALQKLKTAKQLERTWTNQGFLSQ
CCHHHHHHHHHHCCCCCCCCCEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHH
VLGKRLLKEATALLEHPKAQALLKSR
HHHHHHHHHHHHHHHCCHHHHHHCCC
>Mature Secondary Structure
MKFAASLPVVLVGAAAVVVQPQISHALNAAEVAKIARNVTVRVDSQAPGSGVIIKQDGDT
CCCCCCCCCCEECCCCEEECCHHHHHCCHHHHHHHHCCEEEEECCCCCCCCEEEEECCCE
YTVLTAAHVVGSEDTYEVITPDRARHSVANTTIQRLPNVDLALIQFSSSQAYKVAEVGNA
EEEEEEEHHHCCCCCEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEHHCCCC
QQISAGMPCYVAGFPGKTAAINEVVYNFTAGQITANAVQPLRDGYGLVYSNATLPGMSGG
HHHCCCCCEEEECCCCCHHHHHHHHHCCCCCCEEHHHHHHHHCCCEEEEECCCCCCCCCC
AVLDSQGQLIGIHGRADTTPQAQNPNLNPDIYVKTGFNLGIPINTFLQKADDANLDLGFT
EEEECCCCEEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHCCCCCCCEECCC
TPPPKPAAPASVDQALAEAGQALGRGESSKAVSKFNQVLGSDRKAVALHGRGLAHYQRGN
CCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHCCCC
YKEALADLNHAIAIDPYNALFFNSRGSVHLAQALQPNRNLQSGASRAERDFSEALKLNPD
HHHHHHHCCCEEEECCCCEEEECCCCCEEEHHHCCCCCCHHHHHHHHHHHHHHHHCCCCC
DSNAYNNRGLANFYMGARTQAIDDYNQALRLDPGLAKAYKNRGFTRWLEQDIRGALLDLK
CCCCCCCCCCHHHHHCCCHHHHHHHHHHEECCCHHHHHHHCCCHHHHHHHHHHHHHHHHH
QALTIDPTYAPAYQTRGRLQFRQGEVAKAIADYDQAIQLKPKAGKTYIYRGIARYENSEV
HHHCCCCCCCCCHHCCCCEEECCCHHHHHHHCCCHHEEECCCCCCCHHHHHHHHCCCCCC
PGAIQDWQAAIKASPEESAGAHLLIGATLLTQGRENEALQKLKTAKQLERTWTNQGFLSQ
CCHHHHHHHHHHCCCCCCCCCEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHH
VLGKRLLKEATALLEHPKAQALLKSR
HHHHHHHHHHHHHHHCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1368342; 8905231 [H]