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The map label for this gene is mmuM [C]

Identifier: 158334087

GI number: 158334087

Start: 871586

End: 872551

Strand: Direct

Name: mmuM [C]

Synonym: AM1_0903

Alternate gene names: 158334087

Gene position: 871586-872551 (Clockwise)

Preceding gene: 158334086

Following gene: 158334088

Centisome position: 13.4

GC content: 50.93

Gene sequence:

>966_bases
ATGCCTCAATATCGACAAAATTTACCCCAATTATCGAGCGACGTTTTTTTGACGGATGGAGGGCTGGAAACCACTCTGAT
CTTTCATGAAGGCATCGATTTACCTGACTTTGCTGCCTTCGATTTATTGAAAGATAACCAAGGTTATGAAGCCCTTTACG
AGTACTTTCAAACTTATGCTCAGCTCGCTCAGACCTATGAAGTGGGCCTGATCCTAGAAAGTGCGACCTGGCGGGCTAAT
CCAGACTGGGGAACCAAGCTCGGGTATGATGCAGCCGAGTTGGCCGCTGTGAATCGAAATGCGATCGCACTTCTCCATAC
CATTCGCCAGCAATACGAAACCGAAGCTAGCCGCATGGTCATTAGTGGCTGTATCGGCCCTCGGGGAGACGGGTATCAGG
TCGATACGGCCATGACTCCTGCCGAAGCTCAGGTGTATCATCTGCCCCAAATTGAAGCGTTTAAAGAGGCCGAAGCCGAT
ATGGTCAGTGCCGTCACCATGACCTATACCGAGGAAGCCATTGGCATTACTCGGGCGGCCCACCTAGTCGGTATGCCTGT
GGTCATCTCCTTCACTGTGGAAACCGACGGCAAGCTACCGACAGGGCAGGGATTAAAAGATGCGATCGCACAAGTTGATG
CGGCCACGGGCAATGGGCCAATTTATTACATGATTAACTGTGCCCATCCGTCCCATTTCGAGCAGATATTCGCAACCAAC
GAACCTTGGTTAACCCGCATTCATGGACTCCGGGCCAATGCCTCCACCAAAAGTCATGCAGAACTGGATGAAGCGGTCGA
TTTGGATGATGGCAATCCCCAAGAGCTGGGTCAGCAATATTTAAATTTAAGTGATGCTTTGCCCAACCTAAATGTCCTCG
GTGGATGTTGTGGCACCGACCATCGGCATATTGAAGCAATCTGCAAAGCCTGTCTACCAGCGCGGTCAGCCGTCCATGCA
TCCTAA

Upstream 100 bases:

>100_bases
GCTGTGATTGGGACTAGGATCTGGGGTGATAGTGATCATTGTTCTGTTTGTTGAAATCCCACACCCTGAAAGGTATATGC
ATCTAACAGGGGAGCAGCCC

Downstream 100 bases:

>100_bases
GCCAGATCCCCTCATAGCCCCTATGGTCGTCACTGCAGACAAATTTCAATATGGTAATCATAGACATGACCCCTTTCACT
AGCGTCCGGCCATGAGTACC

Product: homocysteine S-methyltransferase

Products: S-adenosyl-L-homocysteine; @METH01txt*L-methionine! [C]

Alternate protein names: Homocysteine/Selenocysteine Methylase; Homocysteine S-Methyltransferase Domain-Containing Protein

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MPQYRQNLPQLSSDVFLTDGGLETTLIFHEGIDLPDFAAFDLLKDNQGYEALYEYFQTYAQLAQTYEVGLILESATWRAN
PDWGTKLGYDAAELAAVNRNAIALLHTIRQQYETEASRMVISGCIGPRGDGYQVDTAMTPAEAQVYHLPQIEAFKEAEAD
MVSAVTMTYTEEAIGITRAAHLVGMPVVISFTVETDGKLPTGQGLKDAIAQVDAATGNGPIYYMINCAHPSHFEQIFATN
EPWLTRIHGLRANASTKSHAELDEAVDLDDGNPQELGQQYLNLSDALPNLNVLGGCCGTDHRHIEAICKACLPARSAVHA
S

Sequences:

>Translated_321_residues
MPQYRQNLPQLSSDVFLTDGGLETTLIFHEGIDLPDFAAFDLLKDNQGYEALYEYFQTYAQLAQTYEVGLILESATWRAN
PDWGTKLGYDAAELAAVNRNAIALLHTIRQQYETEASRMVISGCIGPRGDGYQVDTAMTPAEAQVYHLPQIEAFKEAEAD
MVSAVTMTYTEEAIGITRAAHLVGMPVVISFTVETDGKLPTGQGLKDAIAQVDAATGNGPIYYMINCAHPSHFEQIFATN
EPWLTRIHGLRANASTKSHAELDEAVDLDDGNPQELGQQYLNLSDALPNLNVLGGCCGTDHRHIEAICKACLPARSAVHA
S
>Mature_320_residues
PQYRQNLPQLSSDVFLTDGGLETTLIFHEGIDLPDFAAFDLLKDNQGYEALYEYFQTYAQLAQTYEVGLILESATWRANP
DWGTKLGYDAAELAAVNRNAIALLHTIRQQYETEASRMVISGCIGPRGDGYQVDTAMTPAEAQVYHLPQIEAFKEAEADM
VSAVTMTYTEEAIGITRAAHLVGMPVVISFTVETDGKLPTGQGLKDAIAQVDAATGNGPIYYMINCAHPSHFEQIFATNE
PWLTRIHGLRANASTKSHAELDEAVDLDDGNPQELGQQYLNLSDALPNLNVLGGCCGTDHRHIEAICKACLPARSAVHAS

Specific function: Catalyzes Methyl Transfer From S-Methylmethionine Or S- Adenosylmethionine (Less Efficient) To Homocysteine, Selenohomocysteine And Less Efficiently Selenocysteine. [C]

COG id: COG2040

COG function: function code E; Homocysteine/selenocysteine methylase (S-methylmethionine-dependent)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.10 [C]

Molecular weight: Translated: 35037; Mature: 34905

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: PS50970 HCY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQYRQNLPQLSSDVFLTDGGLETTLIFHEGIDLPDFAAFDLLKDNQGYEALYEYFQTYA
CCCHHHHCCCCCCCEEEECCCCEEEEEEECCCCCCCHHHHHHHCCCCCHHHHHHHHHHHH
QLAQTYEVGLILESATWRANPDWGTKLGYDAAELAAVNRNAIALLHTIRQQYETEASRMV
HHHHHHHHEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHEE
ISGCIGPRGDGYQVDTAMTPAEAQVYHLPQIEAFKEAEADMVSAVTMTYTEEAIGITRAA
HHHCCCCCCCCEEECCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLVGMPVVISFTVETDGKLPTGQGLKDAIAQVDAATGNGPIYYMINCAHPSHFEQIFATN
HHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHCCC
EPWLTRIHGLRANASTKSHAELDEAVDLDDGNPQELGQQYLNLSDALPNLNVLGGCCGTD
CCHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCC
HRHIEAICKACLPARSAVHAS
HHHHHHHHHHHHCCCHHCCCC
>Mature Secondary Structure 
PQYRQNLPQLSSDVFLTDGGLETTLIFHEGIDLPDFAAFDLLKDNQGYEALYEYFQTYA
CCHHHHCCCCCCCEEEECCCCEEEEEEECCCCCCCHHHHHHHCCCCCHHHHHHHHHHHH
QLAQTYEVGLILESATWRANPDWGTKLGYDAAELAAVNRNAIALLHTIRQQYETEASRMV
HHHHHHHHEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHEE
ISGCIGPRGDGYQVDTAMTPAEAQVYHLPQIEAFKEAEADMVSAVTMTYTEEAIGITRAA
HHHCCCCCCCCEEECCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLVGMPVVISFTVETDGKLPTGQGLKDAIAQVDAATGNGPIYYMINCAHPSHFEQIFATN
HHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHCCC
EPWLTRIHGLRANASTKSHAELDEAVDLDDGNPQELGQQYLNLSDALPNLNVLGGCCGTD
CCHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCC
HRHIEAICKACLPARSAVHAS
HHHHHHHHHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-homocysteine; S-Methyl-L-methionine [C]

Specific reaction: S-Adenosyl-L-methionine + L-homocysteine =S-adenosyl-L-homocysteine + @METH01.txt*L-methionine! S-Methyl-L-methionine + homocysteine = 2 L-methionine [C]

General reaction: Methyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA