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The map label for this gene is nagA [H]

Identifier: 158334041

GI number: 158334041

Start: 834100

End: 835266

Strand: Reverse

Name: nagA [H]

Synonym: AM1_0855

Alternate gene names: 158334041

Gene position: 835266-834100 (Counterclockwise)

Preceding gene: 158334042

Following gene: 158334040

Centisome position: 12.84

GC content: 53.38

Gene sequence:

>1167_bases
ATGAGCACTTTACCCATCCGGCTAGAGAATGCTCGGATCATCGGCTACTCAAAATTGCAGGAAGTAGGTATCCAAGATGG
GGTGATTCAGACGATTCAACCCATGGATGCTTTGTCCCTAACGCCCGCCCCGCAAGCAATTGATTTAGCAGGCGATTGGC
TGTCCCTAGGAGGCATTGATTTGCAGATCAATGGCGCGTTAGGCCAAGCCTTTCCCGATTTGACACATACTGACCAAGCA
AAACTACAGGAGATTTGCCAGTTTTTGTGGCAGCAGGGTGTTGACGGTTTCTTGCCAACGTTGGTGACGACGTCCATTGA
AAAGTTTCAGCAAGCCTTGGCTACCCTGTCTACTCAGCGTTCACAAAATGGTAAAGGCCAAGCACAAATTTTAGGTGCCC
ATTTGGAAGGCCCCTGTTTGAATGCCACTAAACGAGGTGCCCATCCCCAGGAATATCTGCAGCCTTTGAGTATTGAAACC
CTACAAGCGGTCATGGGGCCCTACATAGATAGGGTTCGGGTCATCACCTTAGCGCCAGAGTTAGAGCCATCTGGGGAAGC
GGTCGCCTGGTTGCGTTCCCACAATATTATCGTTAGTCTCGGCCATTCCCAGGCCACGGCAGCAGAAGCAGAGGCGGCCT
TTGAGCAGGGTGCTTCTATGGTGACCCATGCCTTTAATGCCATGCCGAGCTTGAACCATCGTCAACCCGGACTATTGGCA
GCAGCATTGATGCACCACCAAGTTTGGTGTGGTTTTATTGCCGATGGTCAGCATGTTGACCCATTGATGCTCAAGCTAAT
GCTTCAGGCTAGCCCTGAGAAGGGCCTATTTCTCGTGAGTGATGCCCTCGCCCCCCTCGGGTTACCGGATGGCGTTTACC
CTTGGGACTCTCGCCAGATTGAAGTAGTGGCAGGGACTGCTCGGCTCCCTGATGGCACTTTGTCCGGAACCACCTTGTCC
CTATTGGCTGGGGTGCAGAATCTAGTCCGCTGGAACCTTTGTTCTGTGGAGCGTGCCATTGCCTTAGGGACAGAAGCGCC
GCGACGGGCTTTAGGGCTACCCGGTCTGGGTCCAGAACAACCGGCTTGCTGTTTGCTGCGTTGGCGTCACCATCCTCAGA
CCCAAACCCTGAAGTGGCAGCGCCTGTTTCCCTCTGAAGATGCTTAA

Upstream 100 bases:

>100_bases
CCTTTTCTGCTGTTTGCCTTTGTGACGACCCTGCTGAATCACATTGAACTGACGCCCGTAGAGCCAAAAGAAGAGGTCTC
AGCTAGCTAGTGTCAAGGCC

Downstream 100 bases:

>100_bases
TGCCTTATGGAAAATCCCTTGTTGCTGATGATTCCGGGTCCCACTCCAGTGCCTGAACCCGTATTGTTTGCTTCGGCTAG
ACAGCCCATCAGCCATCGTA

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MSTLPIRLENARIIGYSKLQEVGIQDGVIQTIQPMDALSLTPAPQAIDLAGDWLSLGGIDLQINGALGQAFPDLTHTDQA
KLQEICQFLWQQGVDGFLPTLVTTSIEKFQQALATLSTQRSQNGKGQAQILGAHLEGPCLNATKRGAHPQEYLQPLSIET
LQAVMGPYIDRVRVITLAPELEPSGEAVAWLRSHNIIVSLGHSQATAAEAEAAFEQGASMVTHAFNAMPSLNHRQPGLLA
AALMHHQVWCGFIADGQHVDPLMLKLMLQASPEKGLFLVSDALAPLGLPDGVYPWDSRQIEVVAGTARLPDGTLSGTTLS
LLAGVQNLVRWNLCSVERAIALGTEAPRRALGLPGLGPEQPACCLLRWRHHPQTQTLKWQRLFPSEDA

Sequences:

>Translated_388_residues
MSTLPIRLENARIIGYSKLQEVGIQDGVIQTIQPMDALSLTPAPQAIDLAGDWLSLGGIDLQINGALGQAFPDLTHTDQA
KLQEICQFLWQQGVDGFLPTLVTTSIEKFQQALATLSTQRSQNGKGQAQILGAHLEGPCLNATKRGAHPQEYLQPLSIET
LQAVMGPYIDRVRVITLAPELEPSGEAVAWLRSHNIIVSLGHSQATAAEAEAAFEQGASMVTHAFNAMPSLNHRQPGLLA
AALMHHQVWCGFIADGQHVDPLMLKLMLQASPEKGLFLVSDALAPLGLPDGVYPWDSRQIEVVAGTARLPDGTLSGTTLS
LLAGVQNLVRWNLCSVERAIALGTEAPRRALGLPGLGPEQPACCLLRWRHHPQTQTLKWQRLFPSEDA
>Mature_387_residues
STLPIRLENARIIGYSKLQEVGIQDGVIQTIQPMDALSLTPAPQAIDLAGDWLSLGGIDLQINGALGQAFPDLTHTDQAK
LQEICQFLWQQGVDGFLPTLVTTSIEKFQQALATLSTQRSQNGKGQAQILGAHLEGPCLNATKRGAHPQEYLQPLSIETL
QAVMGPYIDRVRVITLAPELEPSGEAVAWLRSHNIIVSLGHSQATAAEAEAAFEQGASMVTHAFNAMPSLNHRQPGLLAA
ALMHHQVWCGFIADGQHVDPLMLKLMLQASPEKGLFLVSDALAPLGLPDGVYPWDSRQIEVVAGTARLPDGTLSGTTLSL
LAGVQNLVRWNLCSVERAIALGTEAPRRALGLPGLGPEQPACCLLRWRHHPQTQTLKWQRLFPSEDA

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:
GO:0006044: N-acetylglucosamine-6-phosphate deacetylase
GO:0008448: N-acetylglucosamine-6-phosphate deacetylase

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=388, Percent_Identity=31.701030927835, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI224922791, Length=388, Percent_Identity=31.701030927835, Blast_Score=168, Evalue=9e-42,
Organism=Escherichia coli, GI1786892, Length=333, Percent_Identity=36.036036036036, Blast_Score=181, Evalue=7e-47,
Organism=Caenorhabditis elegans, GI17553768, Length=328, Percent_Identity=36.890243902439, Blast_Score=177, Evalue=6e-45,
Organism=Drosophila melanogaster, GI19920392, Length=358, Percent_Identity=33.7988826815642, Blast_Score=177, Evalue=7e-45,
Organism=Drosophila melanogaster, GI281361140, Length=372, Percent_Identity=32.5268817204301, Blast_Score=172, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 41918; Mature: 41786

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLPIRLENARIIGYSKLQEVGIQDGVIQTIQPMDALSLTPAPQAIDLAGDWLSLGGID
CCCCCEEECCCEEEEHHHHHHCCCCCCHHHHHCCCHHCCCCCCCCEEECCCCCCCCCCEE
LQINGALGQAFPDLTHTDQAKLQEICQFLWQQGVDGFLPTLVTTSIEKFQQALATLSTQR
EEECCCHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SQNGKGQAQILGAHLEGPCLNATKRGAHPQEYLQPLSIETLQAVMGPYIDRVRVITLAPE
CCCCCCCEEEEEEECCCCCCCCHHCCCCHHHHHCCCCHHHHHHHHHHHHCCEEEEEECCC
LEPSGEAVAWLRSHNIIVSLGHSQATAAEAEAAFEQGASMVTHAFNAMPSLNHRQPGLLA
CCCCCCEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
AALMHHQVWCGFIADGQHVDPLMLKLMLQASPEKGLFLVSDALAPLGLPDGVYPWDSRQI
HHHHHHHHHEEEECCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCEE
EVVAGTARLPDGTLSGTTLSLLAGVQNLVRWNLCSVERAIALGTEAPRRALGLPGLGPEQ
EEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCC
PACCLLRWRHHPQTQTLKWQRLFPSEDA
CHHHHHHHCCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
STLPIRLENARIIGYSKLQEVGIQDGVIQTIQPMDALSLTPAPQAIDLAGDWLSLGGID
CCCCEEECCCEEEEHHHHHHCCCCCCHHHHHCCCHHCCCCCCCCEEECCCCCCCCCCEE
LQINGALGQAFPDLTHTDQAKLQEICQFLWQQGVDGFLPTLVTTSIEKFQQALATLSTQR
EEECCCHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SQNGKGQAQILGAHLEGPCLNATKRGAHPQEYLQPLSIETLQAVMGPYIDRVRVITLAPE
CCCCCCCEEEEEEECCCCCCCCHHCCCCHHHHHCCCCHHHHHHHHHHHHCCEEEEEECCC
LEPSGEAVAWLRSHNIIVSLGHSQATAAEAEAAFEQGASMVTHAFNAMPSLNHRQPGLLA
CCCCCCEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
AALMHHQVWCGFIADGQHVDPLMLKLMLQASPEKGLFLVSDALAPLGLPDGVYPWDSRQI
HHHHHHHHHEEEECCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCEE
EVVAGTARLPDGTLSGTTLSLLAGVQNLVRWNLCSVERAIALGTEAPRRALGLPGLGPEQ
EEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCC
PACCLLRWRHHPQTQTLKWQRLFPSEDA
CHHHHHHHCCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]