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The map label for this gene is btuR [C]

Identifier: 158334016

GI number: 158334016

Start: 810156

End: 811286

Strand: Reverse

Name: btuR [C]

Synonym: AM1_0830

Alternate gene names: 158334016

Gene position: 811286-810156 (Counterclockwise)

Preceding gene: 158334024

Following gene: 158334015

Centisome position: 12.47

GC content: 50.49

Gene sequence:

>1131_bases
ATGGCCAGAAATGGGATTGGTATCAATACAGCCCAAGATCGCTCAGAACGTATTGTTGGCCAAATTCACGTTTATGATGG
AGCCGGCAAAGGCAAATCACAAGCGGCCTTGGGGGTGGTATTACGTTCAATTGGTTTAGGCATTGCGTCTGCATTCCCGA
CCCGTGTTCTACTACTACGGTTTTTAAAGGGGCCTGGCCGTCCCTATGCTGAAGATGCTGCCATTGAAGCCTTACAGCGT
GCCTTTCCCCACTTAATTGATCAAGTGCGAACAGGAAGGGCTGAGTTCTTTGGGGCGGACGATATCACCAAGTTTGACCG
CCAAGAAGCTCAACGGGGATGGGATATTGCCAAAGGTGCGATCGCATCCGGTCTCTACTCGGTTGTAGTTCTAGATGAGC
TGAATCCGGTTCTAGATTTAGGACTCCTAGACATCAATGACGTAGTTCAGTCGCTCCGCAAAAAACCTGACCATTTAGAA
GTGATCTCCACAGGGAGAGGGACACCCCAAGGCCTGCTTAATGTTGCCGATCTCCATTCCGAGATGAAACCCCACTCCCA
TGAAGGGACTCGCCAAGGGATTGAAGGGATTGAAATTTATACCGGATCTGGTAAAGGTAAGTCTACGAGTGCTCTCGGTA
AAGCACTTCAGGCCATTGGTCGTGGTATTAGCCAAGACCAATCCCATCGGGTTCTGATTATGCAGTGGCTCAAAGGTGGG
CTTGGGTATACGGAAGATGCAGCCATTTCTGCCATGCAGCAAAGCTATCCCAACCTGGTGGATCATCAGCGTTGTGGTCG
CGATGCCATTGTGTGGCGGGGGCAACAGCAAGAGATTGATTATGTAGAAGCAGAGCGAGGCTGGGAGATTGCCCGAGCAG
CGATCGCATCCGGTCTTTACAAGACCATTATTCTCGATGAGCTGAATCCCACCGTGGATCTGGAACTTCTGCCGGAAGAA
CCGATTATGCAGGCTTTTTTACGTAAACCCCGAGATACCGAAATCATCATCACCGGGCGCTGCCAAAACCCTCCCGCCTA
TTTTGAGTTAGCCAGCACCCATTCCGAGATGGTTTGCCACAAACACTATGCCGAGAAGGGCGTTGATCTCAAACGCGGTG
TAGACTTTTAA

Upstream 100 bases:

>100_bases
GAGAACTTAGTCTTTAAGATAGATTTTGCCCCTCACCATAGGGGATGCCTAAATTACAATCTACCCATTTAATGATTAAA
AGGATAAAGACAGAGTAATT

Downstream 100 bases:

>100_bases
CGAATCTGTTGCAGTTTGCTCATAGATGCCCAGACCCCTCGTTTGACCTTTATGATGGGGGCAGATTCTTATTTCTAGAC
TGAAACAGTTGCTATCCGAA

Product: hypothetical protein

Products: Adenosylcobalamin; Phosphate; Diphosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MARNGIGINTAQDRSERIVGQIHVYDGAGKGKSQAALGVVLRSIGLGIASAFPTRVLLLRFLKGPGRPYAEDAAIEALQR
AFPHLIDQVRTGRAEFFGADDITKFDRQEAQRGWDIAKGAIASGLYSVVVLDELNPVLDLGLLDINDVVQSLRKKPDHLE
VISTGRGTPQGLLNVADLHSEMKPHSHEGTRQGIEGIEIYTGSGKGKSTSALGKALQAIGRGISQDQSHRVLIMQWLKGG
LGYTEDAAISAMQQSYPNLVDHQRCGRDAIVWRGQQQEIDYVEAERGWEIARAAIASGLYKTIILDELNPTVDLELLPEE
PIMQAFLRKPRDTEIIITGRCQNPPAYFELASTHSEMVCHKHYAEKGVDLKRGVDF

Sequences:

>Translated_376_residues
MARNGIGINTAQDRSERIVGQIHVYDGAGKGKSQAALGVVLRSIGLGIASAFPTRVLLLRFLKGPGRPYAEDAAIEALQR
AFPHLIDQVRTGRAEFFGADDITKFDRQEAQRGWDIAKGAIASGLYSVVVLDELNPVLDLGLLDINDVVQSLRKKPDHLE
VISTGRGTPQGLLNVADLHSEMKPHSHEGTRQGIEGIEIYTGSGKGKSTSALGKALQAIGRGISQDQSHRVLIMQWLKGG
LGYTEDAAISAMQQSYPNLVDHQRCGRDAIVWRGQQQEIDYVEAERGWEIARAAIASGLYKTIILDELNPTVDLELLPEE
PIMQAFLRKPRDTEIIITGRCQNPPAYFELASTHSEMVCHKHYAEKGVDLKRGVDF
>Mature_375_residues
ARNGIGINTAQDRSERIVGQIHVYDGAGKGKSQAALGVVLRSIGLGIASAFPTRVLLLRFLKGPGRPYAEDAAIEALQRA
FPHLIDQVRTGRAEFFGADDITKFDRQEAQRGWDIAKGAIASGLYSVVVLDELNPVLDLGLLDINDVVQSLRKKPDHLEV
ISTGRGTPQGLLNVADLHSEMKPHSHEGTRQGIEGIEIYTGSGKGKSTSALGKALQAIGRGISQDQSHRVLIMQWLKGGL
GYTEDAAISAMQQSYPNLVDHQRCGRDAIVWRGQQQEIDYVEAERGWEIARAAIASGLYKTIILDELNPTVDLELLPEEP
IMQAFLRKPRDTEIIITGRCQNPPAYFELASTHSEMVCHKHYAEKGVDLKRGVDF

Specific function: Required For Both De Novo Synthesis Of The Corrin Ring For The Assimilation Of Exogenous Corrinoids. Participates In The Adenosylation Of A Variety Of Incomplete And Complete Corrinoids (By Similarity). [C]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787525, Length=181, Percent_Identity=32.0441988950276, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: 2.5.1.17 [C]

Molecular weight: Translated: 41234; Mature: 41103

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARNGIGINTAQDRSERIVGQIHVYDGAGKGKSQAALGVVLRSIGLGIASAFPTRVLLLR
CCCCCCCCCCCHHHHHCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLKGPGRPYAEDAAIEALQRAFPHLIDQVRTGRAEFFGADDITKFDRQEAQRGWDIAKGA
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHCHHHHHHH
IASGLYSVVVLDELNPVLDLGLLDINDVVQSLRKKPDHLEVISTGRGTPQGLLNVADLHS
HHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHH
EMKPHSHEGTRQGIEGIEIYTGSGKGKSTSALGKALQAIGRGISQDQSHRVLIMQWLKGG
HCCCCCCCCHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCC
LGYTEDAAISAMQQSYPNLVDHQRCGRDAIVWRGQQQEIDYVEAERGWEIARAAIASGLY
CCCCHHHHHHHHHHHCCCHHHHHHCCCCCEEECCCCCCCCHHHHHCCHHHHHHHHHHHHH
KTIILDELNPTVDLELLPEEPIMQAFLRKPRDTEIIITGRCQNPPAYFELASTHSEMVCH
HHHHHHCCCCCEEEEECCCCHHHHHHHCCCCCCEEEEEECCCCCCHHEEEHHHHHHHHHH
KHYAEKGVDLKRGVDF
HHHHHHCCCHHCCCCC
>Mature Secondary Structure 
ARNGIGINTAQDRSERIVGQIHVYDGAGKGKSQAALGVVLRSIGLGIASAFPTRVLLLR
CCCCCCCCCCHHHHHCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLKGPGRPYAEDAAIEALQRAFPHLIDQVRTGRAEFFGADDITKFDRQEAQRGWDIAKGA
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHCHHHHHHH
IASGLYSVVVLDELNPVLDLGLLDINDVVQSLRKKPDHLEVISTGRGTPQGLLNVADLHS
HHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHH
EMKPHSHEGTRQGIEGIEIYTGSGKGKSTSALGKALQAIGRGISQDQSHRVLIMQWLKGG
HCCCCCCCCHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCC
LGYTEDAAISAMQQSYPNLVDHQRCGRDAIVWRGQQQEIDYVEAERGWEIARAAIASGLY
CCCCHHHHHHHHHHHCCCHHHHHHCCCCCEEECCCCCCCCHHHHHCCHHHHHHHHHHHHH
KTIILDELNPTVDLELLPEEPIMQAFLRKPRDTEIIITGRCQNPPAYFELASTHSEMVCH
HHHHHHCCCCCEEEEECCCCHHHHHHHCCCCCCEEEEEECCCCCCHHEEEHHHHHHHHHH
KHYAEKGVDLKRGVDF
HHHHHHCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; Cob(I)alamin; H2O [C]

Specific reaction: ATP + Cob(I)alamin + H2O <==> Adenosylcobalamin + Phosphate + Diphosphate [C]

General reaction: Adenosyl group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840; 7883709 [H]